Quality of life, overweight, and body fat distribution in middle-aged men

Measurements of obesity [body mass index (BMI)] and body fat distribution [waist-to-hip ratio (WHR)] were analyzed in 284 51-year-old men in relation to items about social, mental, and physical well-being from the G?teborg Quality of Life Instrument. Overweight participants (BMI > or = 25) reported a better home-family situation, appetite, and self-esteem, but decreased physical fitness and more pain in the legs compared with their leaner counterparts. Men with abdominal obesity (WHR > or = 1.0) experienced impaired health and physical fitness and lower self-esteem compared with those with WHR < 1.0. The abdominally obese participants were more often exhausted and experienced depressive symptoms. Abdominal pain was more frequent among those with WHR > or = 1.0. Overweight and abdominal obesity seem differently associated with social, mental, and physical well-being in men. Impaired quality of life may be causally related to the development of abdominal obesity; the mechanism involved might be increased cortisol secretion, which can redistribute body fat to central adipose tissue depots.     

Quality of Life,Overweight, and Body Fat Distribution in Middle-Aged Men

Abstract

Measurements of obesity [body mass index (BMI)] and body fat distribution [waist-to-hip ratio (WHR)] were analyzed in 284 51-year-old men in relation to items about social, mental, and physical well-being from the Göteborg Quality of Life Instrument. Overweight participants (BMI ≥ 25) reported a better home-family situation, appetite, and self-esteem, but decreased physical fitness and more pain in the legs compared with their leaner counterparts. Men with abdominal obesity (WHR ≥ 1.0) experienced impaired health and physical fitness and lower self-esteem compared with those with WHR < 1.0. The abdominally obese participants were more often exhausted and experienced depressive symptoms. Abdominal pain was more frequent among those with WHR ≥ 1.0. Overweight and abdominal obesity seem differently associated with social, mental, and physical well-being in men. Impaired quality of life may be causally related to the development of abdominal obesity; the mechanism involved might be increased cortisol secretion, which can redistribute body fat to central adipose tissue depots.     

Android (centralized) obesity and somatotypes in men: association with mesomorphy

The relationship between body fat distribution patterns and somatotype among 824 men was sought from Sheldon, Dupertuis and MacDermott's Atlas of Men (1954). The men were classified photoscopically into obese, overweight and normal weight classes and then into android (central), intermediate and gynoid (generalized) classes of body fat patterning independently and blindly by two observers. Android fat men were found by both observers to be older and more often classed as obese than gynoid fat men. The android obese were significantly more mesomorphic and less endomorphic than the gynoid obese (P less than 0.01). Results suggest that android obesity involves more than an upper body distribution of subcutaneous fat: it is a deep body obesity involving excess lean body mass as well.     

Muscle strengths in relation to fat storage rate in young men

Summary Hand-grip strength, elbow flexion strength, trunk extension strength and knee extension strength, and body composition (measured by densitometry) were measured in 59 male students (mean 19.2 years) in order to compare the muscle strength of obese men, in relation to fat storage rate (% fat), with those of non-obese men. Their % fat ranged from 6.2–35.6%. Correlations of body weight and lean body mass were found to be significant with each muscle strength. Our findings presented that obese men had lower muscle strengths for body weight and lean body mass than non-obese men do. This might be the result of two characteristics, inactivity and weak willpower, of obese men. Besides, the 20% fat of threshold of obesity for men proposed by Behnke and Wilmore was reasonable from the viewpoint of the muscle strength because of the differences between group D (18.8% fat) and group E (23.8% fat).     

Decreased skeletal muscle potassium in obesity

The effect of body weight on total body potassium, skeletal muscle electrolytes and fat content was studied in seven lean and seven obese middle-aged men and seven lean and eight obese middle-aged women. Total body potassium and total body fat increased with body weight (p less than 0.01 and less than 0.05 for men, and p less than 0.05 and p less than 0.001 for women, respectively). So did muscle fat in men (p less than 0.01), while muscle tissue potassium was decreased in both obese men (p less than 0.001) and obese women (p less than 0.05). The skeletal muscle Na/K-ratio tended to be higher in obese men (p less than 0.1) but was not related to body weight in women. Skeletal muscle magnesium was higher (p less than 0.01) in obese men than in lean men. No differences between lean and obese women were found. Obese men had higher diastolic blood pressure (p less than 0.05) than lean men, while there was no difference between obese and lean women. Compared with lean subjects, obese subjects thus had lower relative skeletal muscle mass and men, especially, had more fat and less potassium in the skeletal muscle.     

Variation in the anthropometric dimensions for estimating upper and lower body obesity

A literature review identified 29 anthropometric methods to estimate body fat distribution, but no valid standardized set of criterion values to categorize upper and lower body obesity. The purpose of this investigation was to observe the influence of different anthropometric methods for categorizing upper and lower body obesity. Three common girth methods (waist:iliac crest, iliac crest: hip, and waist:hip) for waist to hip ratios (WHR) and one common skinfold method for trunk to extremity ratio were compared in 119 obese women (38.4 ± 5.3% fat) and 81 obese men (31.3 ± 5.2% fat). Significant differences were found in the WHR among all three girth methods for women, but for only the waist:hip method for men. A significant interaction between method and sex was also apparent. The different WHR methods resulted in a significantly different percentages of the population categorized as having lower, normal, and upper body obesity. Kappa statistics demonstrated significant agreement among the three methods to place subjects into similar fat distribution categories for men (κ = 0.133; z = 4.03), but not for women (κ = 0.059; z = 2.20). There was also no significant correlation between any of the circumference and skinfold methods for men (r = 0.20, 0.10 and 0.15, respectively); yet, significant correlations were found between the iliac crest:hip (r = 0.30) and waist:hip (r = 0.45) methods and the skinfold method for women. In summary, girth methods for estimating body fat distribution in terms of lower and upper body obesity need validation and standardization. © 1994 Wiley-Liss, Inc.     

Insulin sensitivity, insulin secretion, and metabolic and hormonal parameters in healthy women and women with polycystic ovarian syndrome

To study the contributions of body mass, body fat distribution and family history of type 2 diabetes mellitus to hyperinsulinaemia, insulin secretion and resistance in polycystic ovarian syndrome (PCOS), 17 lean (LC) and 17 obese (OC) healthy control subjects, and 15 lean (LPCOS) and 28 obese (OPCOS) women with PCOS were investigated. Waist:hip ratio (WHR), serum concentrations of sex steroids, glucose and insulin during a 75 g oral glucose tolerance test (OGTT), and insulin and C-peptide early phase secretion, and insulin sensitivity index using a euglycaemic hyperinsulinaemic clamp were assessed. The PCOS subjects had a higher mean WHR than the controls. A trend towards hyperinsulinaemia and impairment of insulin sensitivity (including the rates of both glucose oxidation and non-oxidation) was observed in LPCOS subjects, but only in OPCOS subjects were these changes significant. Early phase insulin secretion but not the early phase C-peptide secretion was increased in PCOS subjects compared to controls, suggesting that peripheral hyperinsulinaemia in PCOS women was mainly due to the observed lowered hepatic insulin extraction and insulin resistance in skeletal muscle. Moreover, the presence of a family history of type 2 diabetes did not affect early phase insulin or C-peptide secretion in the PCOS group. These results confirm and strengthen earlier contentions, that insulin resistance is a characteristic defect in PCOS and is worsened particularly by abdominal obesity.     

Stress and body shape: stress-induced cortisol secretion is consistently greater among women with central fat

OBJECTIVE: Excessive central fat puts one at greater risk of disease. In animal studies, stress-induced cortisol secretion has been shown to increase central fat. The objective of this study was to assess whether women with central fat distribution (as indicated by a high waist-to-hip ratio [WHR]), across a range of body mass indexes, display consistently heightened cortisol reactivity to repeated laboratory stressors. METHODS: Fifty-nine healthy premenopausal women, 30 with a high WHR and 29 with a low WHR, were exposed to consecutive laboratory sessions over 4 days (three stress sessions and one rest session). During these sessions, cortisol and psychological responses were assessed. RESULTS: Women with a high WHR evaluated the laboratory challenges as more threatening, performed more poorly on them, and reported more chronic stress. These women secreted significantly more cortisol during the first stress session than women with a low WHR. Furthermore, lean women with a high WHR lacked habituation to stress in that they continued to secrete significantly more cortisol in response to now familiar challenges (days 2 and 3) than lean women with a low WHR. CONCLUSIONS: Central fat distribution is related to greater psychological vulnerability to stress and cortisol reactivity. This may be especially true among lean women, who did not habituate to repeated stress. The current cross-sectional findings support the hypothesis that stress-induced cortisol secretion may contribute to central fat and demonstrate a link between psychological stress and risk for disease.     

不同负荷运动对雄性肥胖模型小鼠性激素和精子质量的影响

BACKGROUND: Overweight and obesity can lead to a disorder of sex hormone in men. The increase in female hormone levels may inhibit the synthesis and secretion of male hormone, increase fat accumulation and form a vicious circle. Exercise can effectively reduce body fat. OBJECTIVE: To investigate the effects of different exercise loads on sex hormone and the quality of sperm in obese male mice. METHODS: Weanling male C57BL/6J mice were divided into normal control group and obesity group. Mice in the obesity group were given high fat diet for 10 weeks to establish mouse model of obesity. The amount of food and water was recorded daily. Body weight was weighed once every week. After model induction, models were assigned to obesity moderate load exercise group and obesity high load exercise group. These models did exercises for 8 weeks. Body length was measured. Body weight, abdominal fat, testis, epididymis and seminal vesicle were weighed. Sperm activity and motility were observed by the sperm counting method in the epididymis tail. Enzyme linked immunosorbent assay was used to measure serum progesterone, follicle stimulating hormone, testosterone and estradiol.  RESULTS AND CONCLUSION: Compared with the normal control group, body weight, abdominal fat weight, and lee’s index were increased (P < 0.01); the coefficient of testis and seminal vesicle were significantly decreased (P < 0.01); serum levels of luteinizing hormone, follicle stimulating hormone and testosterone were significantly decreased and estradiol level was significantly increased (P < 0.05); sperm count and activity were significantly decreased in the obesity group (P < 0.01). Compared with the obesity group, body weight, abdominal fat weight and lee’s index were significantly decreased (P < 0.05 or P < 0.01); the coefficient of testis and seminal vesicle were significantly increased in the obesity moderate load exercise group and obesity high load exercise group (P < 0.05 or P < 0.01). Serum luteinizing hormone, follicle stimulating hormone and testosterone levels were significantly increased (P < 0.05 or P < 0.01); estradiol levels were significantly decreased (P < 0.05); sperm count and activity were significantly increased (P < 0.01, P < 0.05) in the obesity moderate load exercise group. Compared with the obesity moderate load exercise group, abdominal fat weight and lee’s index were significantly reduced (P < 0.05); serum luteinizing hormone, follicle stimulating hormone, testosterone, sperm count and activity were decreased in the obesity high load exercise group (P < 0.01). These results indicate that long-term high fat diet leads to early obesity in males, inhibits the development of the reproductive gland and reproductive organs, and causes the decrease of the level of male hormone and sperm quality. Long-term moderate load exercise effectively reduces body fat, improves the inhibitory effect on male reproductive organs and glands, and relieves the negative effect of obesity on reproductive function. The effect of long-term large load exercise on reducing body fat is better than medium load exercise, but it has little effect on improving the level of male hormone in obese mice or on relieving the negative effect of obesity on reproductive function, even has a tendency to aggravate.       

Prevalence of overweight and obesity for urban adults in Cameroon

BACKGROUND: The emergence of a nutrition transition in developing countries might lead to higher prevalence of obesity and related adverse health effects. In Cameroon,urbanization growth rate is one of the highest in sub-Saharan Africa. Such dramatic demographic change favours important modifications, notably in nutritional patterns. AIM: In this paper we examine the current prevalence of overweight and obesity in Yaounde,the capital city of Cameroon and search for possible causal factors. Detrimental consequences of overweight are also discussed. MATERIAL AND METHODS: Samples of adults (519 women, 252 men) of all ages in all districts of Yaounde were subjected to anthropometric and body composition measurements, blood pressure and resting heart rate determination, and interviewer-administered questionnaires on socio-demography, smoking habits, physical activity, self-perception of body weight and health status. RESULTS: In both sexes body mass index (BMI) increases with age and peaks in the years of maturity. These changes are related to changes in adiposity. Prevalence rates of overweight(BMI >or= 25) and obesity (BMI > or = 30) increase from 20 to 29 years and peak at 40-49 years in men and at 50-59 years in women before starting to decline. One woman in two is overweight and one woman in five is obese, whereas one-third of men are overweight and only 5% are obese. Obese subjects have a larger age-adjusted waist to hip ratio(WHR) than their non-overweight counterparts, attesting that fat gain is oriented towards a more abdominal fat mass distribution. The length of residence in Yaounde, increasing education level, occupation, ethnicity, physical inactivity and smoking practices appear to influence early overweight and/or obesity. No parity effect is observed in women. From the present study, it appears that obesity, and especially obesity in women, could be less benign than that described in other studies in Africa. CONCLUSION: Research is needed in Cameroon, including aetiological and cohort studies aimed at the quantification of morbidity and mortality risks associated with overweight and obesity.     

Obesity and health‐related quality of life: Does social support moderate existing associations?

Objectives Obesity has been shown to be negatively related to physical health‐related quality of life (HQOL) much more strongly than mental HQOL. This is remarkable given findings on obesity‐related social stigmata and associations with depression. Considering obesity as a stressor, this study tests for a moderating role of social support for obesity/HQOL associations among women and men. Design Data come from N=2,732 participants aged 35–74 years in a 2004–2005 general population survey in the Augsburg region, Germany. Methods Body weight and height were assessed by anthropometric measurements (classified by body mass index using WHO standards), social support by the Social Support Questionnaire 14‐item Short‐Form (F‐SozU‐K14) and HQOL by the 12‐item Short‐Form Health Survey (SF‐12). In multiple regression and general linear models, age, education, family status, health insurance, and place of residence were adjusted for. Results Among both genders, obesity was associated with reduced physical but not mental HQOL. Among men reporting strong social support, physical HQOL was impaired neither in the moderately nor the severely obese group (compared with normal weight), while it was given less social support. Among women, poor physical HQOL was associated with obesity regardless of social support. Conclusions In this adult population sample, no association was found for obesity with mental HQOL. In contrast, a negative association with physical HQOL exists for all subgroups except men with strong social support, indicating that social support buffers obesity‐related impairments in physical HQOL in men but not in women. This suggests that obese women and men with strong social support represent distinct populations, with possible implications for obesity care.     

Age-related changes in liver and adipose tissue pyruvate dehydrogenase of genetically obese mice

Changes of the pyruvate dehydrogenase complex in liver and epididymal fat pad were examined longitudinally in obese mice (C57BL/6J-ob/ob) and their lean controls as a function of age. Total pyruvate dehydrogenase in liver was expressed on several reference bases because of differences in hepatic cellularity and protein content between obese mice and their age-matched lean controls. When total hepatic pyruvate dehydrogenase was expressed on a protein basis, the enzyme activity was elevated in obese mice older than 28 weeks in age when compared to lean controls of a similar age. However, when expressed on a DNA basis, total pyruvate dehydrogenase activity in livers of obese mice up to 10 weeks in age was increased when compared to the age-matched lean control. The proportion of hepatic pyruvate dehydrogenase in the active form was also augmented significantly in obese mice from 5 to 28 weeks of age. In 18-week-old obese mice, the proportion of total pyruvate dehydrogenase in the active form of adipose tissue was significantly higher than that of the lean controls. When expressed on a DNA basis, total pyruvate dehydrogenase in the fat pad was also increased in obese mice up to 10 weeks in age when compared to age-matched controls. Total pyruvate dehydrogenase activity in the epididymal fat pad was higher in obese mice than the lean controls in animals as old as 32 weeks in age when the enzyme activity was expressed per 100 g body weight. The increase in the active form and total activity of pyruvate dehydrogenase in both liver and epididymal fat pad during the dynamic early phase of obesity would augment the capacity for acetyl-coenzyme A formation necessary in the support of an accelerated lipogenesis and fat deposition.     

Anaerobic power output of young obese men: Comparison with non-obese men and the role of excess fat

Summary Anaerobic power output was measured by the staircase climb test in 14 obese, 16 lean, and 21 ordinary men aged from 18–22 years. Fat storage rate (%fat) was estimated by densitometry. The obese group ranked highest with an average power output of 1,012 W. This value was significantly higher than those of the other two groups, 890 W for lean subjects and 855 W for ordinary subjects. The power output per kilogram of lean body mass of the obese group was the highest also. However, the vertical velocity was the lowest although the difference among the three average values was not statistically significant. To investigate the effect of excess fat, eight non-obese subjects engaged in an added-weight experiment. The value obtained was almost the same as for the obese group. The added weights made the vertical velocity decrease but the power output increase. Consequently, it was obvious that the excess fat of an obese man played a role only as an inert mass in the power output measurement. A significantly higher power output of the obese group might be due to more excess fat, and obesity itself was an advantage in the staircase climb test.     

Behavior and metabolic disease

The link between behavioral factors and disease is not well-defined. Although connections between a fight-flight reaction to environmental stress and hypertension have been much discussed, a potential disease association to a defeat-type of reaction has been much less considered. This is characterized by an elevated activity of the hypothalamo-pituitary-adrenal (HPA) axis, which is difficult to measure over a sufficiently long period of time. There is now considerable evidence that the characteristic peripheral endocrine abnormalities following a chronic HPA axis activation is directing storage fat to central, visceral adipose tissue depots. This evidence come from detailed molecular and cellular studies, clinical observation, and intervention trials, as well as from statistical associations between visceral fat accumulation and HPA axis activation in a number of conditions. Central fat accumulation measured conveniently as the waist/hip circumference ratio (WHR), is therefore probably a surrogate measurement for a chronic or repeated activation of the HPA axis. The WHR consequently provides a possibility to examine connections between environmental factors resulting in a hyperactive HPA axis, which is a consequence of a defeat-type of reaction to perceived stress. Such statistical associations have been examined in several population samples. The WHR has been found to be linked to a number of psychosocial and socioeconomic handicaps among both men and women, as well as to traits of psychiatric disease and use of alcohol and tobacco. Measurements of moderate obesity without WHR elevation often show reverse relations. It is suggested that measurements of central fat distribution such as the WHR may be used as a surrogate for chronic or repeated HPA axis activation, a consequence of a defeat-type of reaction to perceived environmental stress. This may provide a novel, convenient method to trace adverse bodily consequences of environmental stress leading to disease. This is also suggested by the fact that the WHR is now an established, unusually powerful risk factor for several prevalent diseases, which were previously suggested to have links to psychosocial and socioeconomic handicaps.     

The effects of fatness and fat distribution on respiratory functions

BACKGROUND: Inverse relationships between respiratory function and indices of obesity and fat distribution have been reported, but it remains unclear which measure of obesity shows the strongest relationship with lung function. AIM: The study assessed the effect of fatness and fat distribution on respiratory function. SUBJECTS AND METHODS: A sample of 423 males and 509 females aged 40-50 years were examined in the Silesian Centre for Preventive Medicine, DOLMED, in Wroc?aw in 1995. The strength of influence of height, body mass index (BMI), wait-to-hip ratio (WHR) and abdominal and subscapular skinfolds upon forced vital capacity (FVC) and forced expiratory volume in a 1-s expiration (FEV1) was assessed by multiple regression analysis. RESULTS: In males, FVC was strongly positively associated with height and BMI, but negatively associated with subscapular and abdominal skinfolds, WHR, and smoking. FEV1 showed a positive relationship with height, BMI and WHR. In females, both FVC and FEV1 showed significant positive associations with height, negative ones with subscapular skinfold, and no association with either WHR or abdominal skinfold. In males, respiratory function is affected to a similar extent by fat in the abdominal region and by fatness of the chest. In females, fatness of the thorax has the strongest relationship with respiratory function. CONCLUSION: Fatness tends to impair respiratory function in both sexes but these effects show a different pattern in males and females. In males, respiratory functions are significantly, and to a similar extant, affected by fatness in the abdominal region, both subcutaneous and visceral, and by fatness on the chest. In females, it is primarily subcutaneous fat on the upper thorax that affects respiratory functions, while visceral and subcutaneous abdominal fatness play little or no role.     

Prevalence of overweight and obesity for urban adults in Cameroon

Background: The emergence of a nutrition transition in developing countries might lead to higher prevalence of obesity and related adverse health effects. In Cameroon, urbanization growth rate is one of the highest in sub-Saharan Africa. Such dramatic demographic change favours important modifications, notably in nutritional patterns. Aim: In this paper we examine the current prevalence of overweight and obesity in Yaoundé, the capital city of Cameroon and search for possible causal factors. Detrimental consequences of overweight are also discussed. Material and methods: Samples of adults (519 women, 252 men) of all ages in all districts of Yaoundé were subjected to anthropometric and body composition measurements, blood pressure and resting heart rate determination, and interviewer-administered questionnaires on socio-demography, smoking habits, physical activity, self-perception of body weight and health status. Results: In both sexes body mass index (BMI) increases with age and peaks in the years of maturity. These changes are related to changes in adiposity. Prevalence rates of overweight (BMI ≥ 25) and obesity (BMI ≥ 30) increase from 20 to 29 years and peak at 40-49 years in men and at 50-59 years in women before starting to decline. One woman in two is overweight and one woman in five is obese, whereas one-third of men are overweight and only 5% are obese. Obese subjects have a larger age-adjusted waist to hip ratio (WHR) than their non-overweight counterparts, attesting that fat gain is oriented towards a more abdominal fat mass distribution. The length of residence in Yaoundé, increasing education level, occupation, ethnicity, physical inactivity and smoking practices appear to influence early overweight and/or obesity. No parity effect is observed in women. From the present study, it appears that obesity, and especially obesity in women, could be less benign than that described in other studies in Africa. Conclusion: Research is needed in Cameroon, including aetiological and cohort studies aimed at the quantification of morbidity and mortality risks associated with overweight and obesity.     

云南省纳西、普米、傈僳族肥胖状况分析及受试者工作特征曲线对高血压的预警作用

目的 探讨云南省丽江市纳西、普米、傈僳族的肥胖流行状况和高血压的患病情况,并计算身体质量指数（BMI）、腰围、内脏脂肪等级的临界点来预警高血压,为高血压防治工作提供参考。方法 选取18～90岁纳西、普米、傈僳族1471名,采用活体测量的方法对其身体形态指标进行测量,并测量血压,使用 Logistic 回归分析肥胖对高血压的影响,以BMI、腰围、内脏脂肪等级绘制各民族受试者工作特征（ROC）曲线。使用IBM SPSS 24.0统计学软件对数据进行处理。结果 688名纳西族中肥胖108人（15.7%）,腹型肥胖385人（56%）,内脏脂肪超标197人（28.5%）;513名普米族中肥胖46人（9%）,腹型肥胖279人（54.4%）,内脏脂肪超标113人（22%）;270名傈僳族中肥胖率24人（8.9%）,腹型肥胖121人（44.8%）,内脏脂肪超标54人（20%）。3个民族肥胖、腹型肥胖、内脏脂肪超标的总体分布差异均存在统计学意义（χ2=15.724、10.007、10.886,P<0.05）。纳西族肥胖、腹型肥胖、内脏脂肪超标率最高（P<0.05）。高血压患病601人（40.9%）,腹型肥胖和内脏脂肪超标是高血压的危险因素（OR=0.676, 0.456,P<0.05）。可选用BMI、腰围、内脏脂肪等级预警高血压（AUC >0.5, P<0.05）。结论 纳西族、普米族和傈僳族的肥胖率等处于较高水平,可通过监测腰围和BMI来预防高血压的发病并对提早防治高血压具有重要意义。     

纳西族成人各项肥胖指标与体脂率的关系

目的 探讨纳西族各项肥胖指标与体脂率的关系。 方法 选取云南省丽江市玉龙县687名18~90岁成年纳西族人,运用人体测量法和生物电阻抗法测量其体重、身高、胸围、腰围、臀围、肱二头肌皮褶、肱三头肌皮褶、肩胛下皮褶、髂嵴上皮褶、髂前上棘皮褶、体质量指数（BMI）、内脏脂肪等级和体脂率等指标,并将各项指标分别与体脂率进行统计分析。 结果 纳西族成人的平均体脂率男性为正常水平,女性属于肥胖。按照内脏脂肪等级为标准,纳西族男性和女性均在正常范围内。根据腰围的判断标准,纳西族男性腰围在正常范围内,而女性腰围属于腹型肥胖。相关分析表明,纳西族成人的体重、胸围、腰围、臀围、肱二头肌皮褶、肱三头肌皮褶、肩胛下皮褶、髂嵴上皮褶、髂前上棘皮褶、BMI、内脏脂肪等级与体脂率均成正相关。纳西族男性内脏脂肪等级与体脂率相关性最强,其次是BMI;纳西族女性胸围与体脂率相关性最强,其次是腰围。 结论 纳西族成人各项肥胖指标均与体脂率成正相关,相关程度存在性别、地区和民族差异。     

The effects of fatness and fat distribution on respiratory functions

Background: Inverse relationships between respiratory function and indices of obesity and fat distribution have been reported, but it remains unclear which measure of obesity shows the strongest relationship with lung function.

Aim: The study assessed the effect of fatness and fat distribution on respiratory function.

Subjects and methods: A sample of 423 males and 509 females aged 40–50 years were examined in the Silesian Centre for Preventive Medicine, DOLMED, in Wroc?aw in 1995. The strength of influence of height, body mass index (BMI), wait-to-hip ratio (WHR) and abdominal and subscapular skinfolds upon forced vital capacity (FVC) and forced expiratory volume in a 1-s expiration (FEV₁) was assessed by multiple regression analysis.

Results: In males, FVC was strongly positively associated with height and BMI, but negatively associated with subscapular and abdominal skinfolds, WHR, and smoking. FEV₁ showed a positive relationship with height, BMI and WHR. In females, both FVC and FEV₁ showed significant positive associations with height, negative ones with subscapular skinfold, and no association with either WHR or abdominal skinfold. In males, respiratory function is affected to a similar extent by fat in the abdominal region and by fatness of the chest. In females, fatness of the thorax has the strongest relationship with respiratory function.

Conclusion: Fatness tends to impair respiratory function in both sexes but these effects show a different pattern in males and females. In males, respiratory functions are significantly, and to a similar extant, affected by fatness in the abdominal region, both subcutaneous and visceral, and by fatness on the chest. In females, it is primarily subcutaneous fat on the upper thorax that affects respiratory functions, while visceral and subcutaneous abdominal fatness play little or no role.     

哈萨克族成人6种肥胖评价指标准确性比较

目的 比较身体质量指数（BMI）、腰围（WC）、腰臀比（WHR）、腰围身高比（WHtR）、肥胖指数（BAI）、体脂率（PBF）对哈萨克族肥胖筛查的准确性,并确定6种指标在判断哈萨克族肥胖的最佳切点。方法 采用卡方检验、直线相关分析及受试者工作特征曲线（ROC）分析,比较BMI、WC、WHR、WHtR、BAI、PBF对肥胖预测的准确性,并确定各项指标的最佳切点。结果 经卡方检验分析结果显示,WC与WHtR、BMI与BAI对哈萨克族肥胖判断的结果相近。在直线相关分析中,BMI、WC与身体脂肪含量具有很强的相关性。ROC曲线分析显示,WC的曲线下面积(AUC)最大,其次是BMI。 结论 哈萨克族是超重、肥胖的高发人群,腰围对哈萨克族肥胖筛查的准确性最高,建议使用BMI、WC及WHtR 3项指标共同判定哈萨克族肥胖情况。