下腔静脉扩张成形术及支架植入术治疗节段性闭塞型Budd-Chiari综合征16例

目的　探讨下腔静脉节段性闭塞型Budd Chiari综合征的介入治疗。方法　本组 16例 ,采用Brockenbroug穿刺针行闭塞段再通术 ,而后行经皮球囊导管成形术 (PTA)及血管内支架植入术。结果　本组 16例行闭塞段再通术、PTA及血管内支架植入术均获成功 ,术后下腔静脉压由术前 ( 2 3 .6± 3 .5 )cmH2 O降至 ( 10 .5± 2 .6)cmH2 O ,术后患者主要症状及体征即有不同程度好转 ,本组随访 2～ 2 5个月 ,平均 9个月 ,5例未见临床症状及体征复发 ,2例出现支架内闭塞。结论　对节段性闭塞型BCS ,合理的治疗方法是PTA后置入内支架 ,可迅速有效地改善临床症状及体征 ,并可有防止再狭窄的发生。     

下腔静脉狭窄闭塞型布加综合征的介入治疗

近年来,介入技术以其安全、有效、微创等优点成为布加综合征(Budd-Chiari Syndrome,BCS)治疗的首选.本文介入治疗下腔静脉型BCS患者28例,总结如下.     

肝静脉狭窄或闭塞型Budd-Chiari综合征的介入治疗

近年来应用介入放射学技术治疗Budd-Chiari综合征取得了令人满意的临床效果,并已基本取代外科手术.     

肝静脉狭窄或闭塞型Budd-Chiari综合征的介入治疗

近年来应用介入放射学技术治疗Budd Chiari综合征取得了令人满意的临床效果 ,并已基本取代外科手术。但是 ,对肝内静脉分支和主干广泛狭窄或闭塞型Budd Chiari综合征 ,采用常规的球囊扩张、内支架置入等介入治疗方法效果不佳。我院于 1993年 5月～2 0 0 2年 10月应用经颈静脉肝内门体静脉分流术 ,治疗肝内静脉分支和主干均狭窄或闭塞的Budd Chiari综合征 9例 ,临床效果满意 ,现报告如下。1　临床资料1 1　一般资料　本组 9例 ,均经超声、CT和血管造影证实为肝内静脉分支和主干狭窄或闭塞型Budd Chiari综合征 ,男 6例 ,女 3例 ;年龄 2 1…     

经皮球囊扩张术治疗下腔静脉节段型完全闭塞综合征

在右房及下腔静脉对端双向造影基础上,对5例下腔静脉节段型完全闭塞者,采用房间隔穿刺针穿通过闭塞段,F14扩张器预扩后,行经皮球囊下腔静脉腔内成形术(PTA)。术后造影及多普勒超声检查示下腔静脉完全闭塞段的内径平均开通至(13.0±2.1)mm,下腔静脉压力从(4.51±1.48)kPa降至(2.53±0.79)kPa,闭塞段远端下腔静脉内径从(29.4±1.9)mm减小至(22.1±2,3)mm,症状明显改善,无并发症;文中讨论了手术方法及可能出现的并发症。此法完全可靠,疗效显著,具有较大的实用性,值得推广。     

Budd-Chiari综合征的临床研究

目的 :进行Budd Chiari综合征的临床研究 ,提高诊断水平。方法 :通过经下腔静脉造影确诊的 2 2例Budd Chiari综合征患者进行临床分析。结果 :B超检查 17例 ,下腔静脉肝段节段性闭塞 9例 ,膜状闭塞 2例 ,肝静脉闭塞 3例 ;下腔静脉造影 ,肝静脉闭塞型 (Ⅰ型 ) 6例 ,肝段下腔静脉开口处闭塞型 (Ⅱ型 ) 16例 ,下腔静脉闭塞长度 1～ 9cm。临床突出表现为门静脉和下腔静脉两个血流系统的高压征 ,可见腹水 ,肝脾肿大 ,侧枝循环形成 ,下肢水肿 ,静脉曲张和色素沉着 ,胸腹腰背部浅静脉呈垂直方向长链状上行性曲张。结论 :Budd Chiari综合征临床表现复杂多样 ,易造成误诊 ,B超检查可作为筛选本病的有效手段     

Budd-Chiari氏综合征伴有下腔静脉梗阻(附3例报告和文献复习)

本文报告Budd-Chiari氏综合征伴有下腔静脉梗阻3例。并结合文献对本病之病因、病程、诊断及治疗作一简要复习。重点讨论了诊断及治疗方法。     

Budd-Chiari综合征中下腔静脉阻塞膜与肝右静脉的位置关系研究

目的分析下腔静脉阻塞膜与肝右静脉的位置关系,探讨Budd-Chiari综合征（BCS）可能的病因学。方法 35例下腔静脉IVC膜性阻塞性病变患者,DSA观察下腔静脉CIVC阻塞膜与肝静脉的位置关系。结果膜位于肝右静脉以上者32例,肝右静脉以下者3例。膜位于肝右静脉与肝左、中静脉之间者3例,位于三支HV以上者4例。结论某些低毒性物质的作用和IVC壁的损伤可能为BCS发病的始动因素。     

Budd-Chiari综合征的影像学表现

Budd-Chiari 综合征（Budd-Chiari syndrome, BCS）是一种罕见的疾病, 由于早期症状无特异性, 很容易造成漏诊、误诊, BCS 的早期诊断和及时治疗是提高患者生存率和生活质量的关键。 随着影像技术的不断进步, 影像检查在 BCS 的诊断和病情评估中起着越来越重要的作用。 超声、CT、MRI 和数字减影血管造影（digital subtraction angiography, DSA）对于肝静脉、下腔静脉阻塞情况的评估均有较大的帮助, 在临床工作中应结合各种检查的特点合理利用;另一方面, 介入治疗已经成为 BCS 治疗的首选方法。 本文对近年来国内外关于 BCS 影像学表现的研究作一综述, 旨在加深临床医师对 BCS 的认识, 以便及时作出正确的诊断。     

仰卧急性下腔静脉受压综合征

晚期妊娠产妇的血液动力学改变显著。剖腹产妇在未行麻醉或手术之前,其血压、脉搏有时变化急剧,甚至完全消失,出现严重虚脱,可能造成严重后果。我院近年来发现2例急性下腔静脉受压综     

To restrict indication for stenting of the inferior vena cava and liver transplantation in patients with Budd-Chiari syndrome

The Budd-Chiari syndrome (BCS) used to be a very rare disorder and lacked a means of relieving. However, various shuntings and radical procedures have emerged in the last three decades with quite encouraging outcomes. Recent minimally invasive therapies, such as stenting of the inferior vena cava (IVC), are simple and easy to handle. However, it has been realized that the IVC stent may compromise the hepatic veins and cause catastrophic consequences, thus the indication for IVC stenting should be reevaluated and especially not to be overused. Instead, it should be applied by percutaneous transangiography (PTA) only, which may be repeated when necessary. The BCS in China predominantly belongs to the IVC type rather than the intrahepatic type in Western; the outcome from its conventional therapy, at least for the moment, is better than that of liver transplantation. It is thus suggested that, before liver transplantation is decided, the conventional means for managing BCS be considered. The final suggestion is to restrict the indication both for stenting of the IVC and liver transplantation. In this paper, ten examples are given with figures.     

布-加氏综合征的外科治疗体会

目的通过总结58例布-加氏综合征的外科治疗,探讨其手术方法及疗效。方法回顾性分析1997-09-2004-10的58例临床及随访资料,均经右后外侧切口开胸,行下腔静脉切开狭窄段直视疏通,其中18例利用心包或人造血管加宽。结果术后症状缓解,下腔静脉压力平均下降1．5cmH2O。结论下腔静脉直视疏通能有效地解除下腔静脉及门静脉系统高压,达到根治目的。     

Retrievable and permanent inferior vena cava filters: selected considerations

The use of inferior vena cava (IVC) filters is increasing rapidly, and the recent availability of retrievable IVC filters is certain to accelerate this process. Unfortunately, because the risks and benefits of these devices have not been adequately studied, several important issues remain. Limitations of the quality of the data in the available literature make it virtually impossible to accurately quantify the specific rates of complications with various devices. Although many clinicians believe that the use of an IVC filter obviates anticoagulation, new data support the need for long-term anticoagulation in such patients. The recent introduction of retrievable IVC filters may eliminate the need for long-term anticoagulation if the filter can be removed, but further data are needed to ascertain the place of these devices in modern therapy. The increasing use of these devices increases the need for clinicians to be aware of the potential limitations and risks of IVC filters.     

Contraction of guinea pig inferior vena cava by eicosanoids

Summary Guinea pig inferior vena cava contracted in response to leukotriene (LT)C₄, LTD₄, LTE₄ U46619, phenylephrine, histamine, and KCl. Although LTC₄, LTD₄, and U46619 were the most potent agonists, active tension generated by these eicosanoids was only about half that of histamine or KCl. LTE₄ and phenylephrine were marginally active. Biochemical analysis showed vena cava able to convert about 23% LTC₄ to LTD₄ and LTE₄ in 45 min. Pretreatment with acivicin prevented this by abrogating conversion of LTC₄ to LTD₄. A subthreshold concentration of LTE₄ reduced responses to LTC₄ and LTD₄. LY171883 and WY-48252 competitively antagonized LTD₄-induced contractions of vena cava. In contrast, these antagonists blocked contractions to LTC₄ in a biphasic manner. Lower segments of the LTC₄ concentration-response curves were less affected than the upper portion suggesting the possibility of 2 LTC₄ receptor subtypes. Our results indicate that LTE₄ is a weak or partial agonist in this tissue and furthermore they suggest a lack of high affinity receptors for LTE₄ favoring LTC₄ and LTD₄. Indomethacin did not influence contractions to the leukotrienes or histamine. However, the response to U46619 was greatly enhanced suggesting release of a vasodilator prostaglandin as part of the overall response of the vena cava to the thromboxane A2 mimetic.Presented in part at a meeting of the American Society for Pharmacology and Experimental Therapeutics, Salt Lake City, Utah Correspondence to: J. H. Fleisch at the above address