Factors influencing dyspepsia‐related consultation: differences between a rural and an urban population

Background Dyspepsia is a common, chronic condition but medical consultation rates for symptoms remain variable. We aimed to examine two populations with varied health‐care provision to determine predictive factors for dyspepsia‐related consultation. Methods A cross‐sectional, population‐based study in both an urban and a rural community within a single Asian country was conducted. Details on dyspepsia‐related consultation rates over a fixed period and independent factors influencing them were identified. Key Results A total of 4039/5370 (75.2%) adults from representative rural and urban areas in this country agreed to participate in the study. Although mean ages of respondents were similar (40.4 years), the demographics of both populations varied in terms of gender (62.7% female, rural vs 55.7% female, urban, P < 0.0001), marital status (75.4% rural vs 70.5% urban, P = 0.002), ethnicity, (79% Malay rural vs 45.3% Malays urban, P < 0.0001) and socio‐economic status (professional occupation 7.1% rural vs 47.3% urban, P < 0.0001). Dyspepsia‐related consultation rates were found to be higher among rural compared to urban adults (41.4%vs 28.7%, P < 0.0001). Over‐the‐counter medication consumption was higher among urban compared to rural dyspepsia sufferers (n = 157 vs n = 35, P < 0.0001). Following logistic regression, rural population (OR 3.14, 95% CI = 1.65–6.0), low quality of life (OR 1.90, 95% CI = 1.17–3.10), and self‐medication (OR 0.40, 95% CI = 0.25–0.62) were found to independently predict dyspepsia‐related consultation. Conclusions & Inferences Dyspepsia‐related consultation varied significantly between urban and rural communities. Factors within the rural population, self‐medication practices, and a low quality of life independently influenced dyspepsia‐related consultation.     

Feeling bad on Facebook: depression disclosures by college students on a social networking site

Background: Depression is common and frequently undiagnosed among college students. Social networking sites are popular among college students and can include displayed depression references. The purpose of this study was to evaluate college students' Facebook disclosures that met DSM criteria for a depression symptom or a major depressive episode (MDE). Methods: We selected public Facebook profiles from sophomore and junior undergraduates and evaluated personally written text: “status updates.” We applied DSM criteria to 1‐year status updates from each profile to determine prevalence of displayed depression symptoms and MDE criteria. Negative binomial regression analysis was used to model the association between depression disclosures and demographics or Facebook use characteristics. Results: Two hundred profiles were evaluated, and profile owners were 43.5% female with a mean age of 20 years. Overall, 25% of profiles displayed depressive symptoms and 2.5% met criteria for MDE. Profile owners were more likely to reference depression, if they averaged at least one online response from their friends to a status update disclosing depressive symptoms (exp(B) = 2.1, P<.001), or if they used Facebook more frequently (P<.001). Conclusion: College students commonly display symptoms consistent with depression on Facebook. Our findings suggest that those who receive online reinforcement from their friends are more likely to discuss their depressive symptoms publicly on Facebook. Given the frequency of depression symptom displays on public profiles, social networking sites could be an innovative avenue for combating stigma surrounding mental health conditions or for identifying students at risk for depression. Depression and Anxiety, 2011. © 2011 Wiley‐Liss, Inc.     

Associations between problematic Internet use and psychiatric symptoms among university students in Japan

Aim

Research on the adverse effects of Internet use has gained importance recently. However, there is currently insufficient data on Japanese young adults’ Internet use, so we conducted a survey targeting Japanese university students to research problematic Internet use (PIU). We also investigated the relationship between PIU and multiple psychiatric symptoms.

Methods

A paper‐based survey was conducted at five universities in Japan. Respondents were asked to fill out self‐report scales regarding their Internet dependency using the Internet Addiction Test (IAT). Sleep quality, attention‐deficit hyperactivity disorder (ADHD) tendency, depression, and anxiety symptom data were also collected based on respective self‐reports.

Results

There were 1336 responses and 1258 were included in the analysis. The mean IAT score (± SD) was 37.87 ± 12.59; and 38.2% of participants were classified as PIU, and 61.8% as non‐PIU. The trend level for young women showed that they were more likely to be classified as PIU than young men (40.6% and 35.2% respectively, P = 0.05). Compared to the non‐PIU group, the PIU group used the Internet longer (P < 0.001), had significantly lower sleep quality (P < 0.001), had stronger ADHD tendencies (P < 0.001), had higher Depression scores (P < 0.001), and had higher Trait‐Anxiety scores (P < 0.001). Based on multiple logistic regression analyses, the factors that contributed to an increased risk of PIU were: being female (odds ratio [OR] = 1.52), being older (OR = 1.17), having poor sleep quality (OR = 1.52), having ADHD tendencies (OR = 2.70), having depression (OR = 2.24), and having anxiety tendencies (OR = 1.43).

Conclusion

We found a high PIU prevalence among Japanese young adults. The factors that predicted PIU were: female sex, older age, poor sleep quality, ADHD tendencies, depression, and anxiety.     

10‐Year trends in the treatment and outcomes of patients with first‐episode schizophrenia

Nielsen J, le Quach P, Emborg C, Foldager L, Correll CU. 10‐Year trends in the treatment and outcomes of patients with first‐episode schizophrenia. Objective: The first episode of schizophrenia is a critical period for illness course and outcomes. We aimed to investigate treatments and outcomes during the first year after the diagnosis of schizophrenia. Method: Pharmacoepidemiologic inception cohort study of all newly diagnosed patients with schizophrenia in Denmark (n = 13 600) 1996–2005. Results: From 1996 to 2005, the mean age at first diagnosis decreased significantly (29.2–26.1 years), more patients received antipsychotics (67.2–80.7%, annual OR = 1.07, CI: 1.06–1.09, P < 0.001) and antipsychotic polypharmacy for >4 months (16.7–37.1%, OR = 1.14, CI: 1.12–1.57, P < 0.001). The antipsychotic defined daily dosage (DDD) doubled (150–332 DDD, P < 0.001), use of antidepressants (24.3–40.6%, P < 0.001). Bed days [89.9 days (CI: 81.8–98.8) to 71.8 days, CI: 63.7–80.8, P < 0.0001] decreased, whereas outpatient contacts [10.2 (CI: 9.5–11.0) to 21.4 (CI: 19.9–21.0), P < 0.0001] doubled. Conclusion: Between 1996 and 2005, there was an earlier recognition of schizophrenia, intensified outpatient treatment, increased use and dosing of antipsychotics and antidepressants, but also more antipsychotic polypharmacy.     

The prevalence of migraine in university students: a systematic review and meta‐analysis

Our aim was to determine the prevalence of migraine amongst university students. Migraine is highly prevalent amongst university students, but the exact frequency remains inconsistent between studies. PubMed, Embase and Google Scholar databases were used to identify studies dealing with the prevalence of migraine amongst university students published between 1 January 1988 and 31 August 2014. The pooled migraine prevalence was calculated using DerSimonian and Laird's random‐effects model. Heterogeneity of the results was investigated using subgroup analysis and the trend of migraine prevalence according to the publication year and sample size was determined by cumulative analysis. Data were combined from 56 independent studies, analysing a total of 34 904 students. The pooled migraine prevalence was 16.1% [95% confidence interval (CI) 13.6%–18.9%]: 11.3% (95% CI 8.8%–14.4%) amongst male students and 21.7% (95% CI 18.0%–25.8%) amongst female students. Subgroup analysis revealed that diagnostic criteria (P < 0.0001) and gender distribution (P = 0.004) significantly affected migraine prevalence. Cumulative analysis found that the 95% CI became narrower with ascending publication year and sample size. Many studies agree that migraine is highly prevalent amongst university students, but diverse methodologies lead to substantial heterogeneity in the results. It is shown that gender and diagnostic criteria significantly influence the migraine prevalence and may partially explain the heterogeneity between studies.     

Morphological changes of the internal carotid artery: prevalence and characteristics. A clinical and ultrasonographic study in a series of 19 804 patients over 25 years old

Background and purpose

Morphological changes of the internal carotid arteries (McICA) are frequently found during cervical ultrasound studies. However, the etiology of McICA remains controversial. During this study, the prevalence and demographic characteristics of McICA, such as kinking, coiling or looping identified by Doppler ultrasound, were analysed and its relationship with vascular risk factors and stroke was assessed.

Methods

A retrospective study was performed by analysing 19 804 patients who were subjected to cervical ultrasonographic study between January 2000 and June 2012. The data were statistically analysed with SPSS^® 20 and a multivariate logistic regression was performed. Statistical significance was accepted for P < 0.05 and 95% confidence intervals (CIs) were used.

Results

Morphological changes of the internal carotid arteries were present in 2678 patients (13.5%) and were unilateral in 61.6% of these cases. Carotid kinking was found in 80% of the patients, coiling in 16% and looping in 1%. In multivariate analysis, the presence of McICA was related to older groups (1.04; 95% CI, 1.04–1.05; P < 0.01), female gender (1.78; 95% CI, 1.64–1.94; P < 0.01), patients with hyperlipidemia (1.28; 95% CI, 1.17–1.40; P < 0.01), carotid thickness (1.22; 95% CI, 1.13–1.33; P < 0.01) and cardiac or cardioembolic disease (1.11; 95% CI, 1.01–1.21; P = 0.02). The results of this study indicate that kinking in the carotid artery was associated with ipsilateral cerebral ischemic events (1.43; 95% CI, 1.040–1.958; P < 0.05).

Conclusion

Morphological changes of the internal carotid arteries were associated with aging, female gender and patients with hyperlipidemia, hypertension, diabetes and heart disease. Kinking was associated with ipsilateral cerebral ischemia.     

Passive properties of the muscle‐tendon unit: The influence of muscle cross‐sectional area

The purpose of the present study was to examine the relationships among the passive properties of the muscle–tendon unit and muscle cross‐sectional area (CSA). Our findings indicated significant relationships between muscle CSA and passive stiffness (P < 0.05; r = 0.830) and muscle CSA and passive energy absorption (P < 0.05; r = 0.765). Since passive stiffness and the ability to absorb passive energy decreases with many diseases, these findings may support the need to maintain or increase muscle CSA. Muscle Nerve 39: 227–229, 2009     

Social Support and Stress Among University Students in Jordan

The purpose of this study was to examine the relationship between perception of social support and perceived stress among university students in Jordan. A sample of 241 university students from private and government universities in Jordan answered self-report questionnaires including the perceived social support scale and perceived stress scale. The results showed that university students have moderate perception of social support and stress. Female university students had higher perception of stress and social support than male university students. Perceived stress had a negative correlation with perceived social support from family (−0.29, p < 0.05). The perceived social support from family was a better predictor of perceived life event as stressful situations than perceived social support from friends. The study implications for research and intervention were discussed.     

Eveningness relates to burnout and seasonal sleep and mood problems among young adults

Aims: Diurnal preference towards eveningness among adults has been associated with unhealthy habits and a range of health hazards, such as sleeping problems and higher odds for depression. We wanted to analyse whether diurnal preference towards eveningness is associated with more severe symptoms regarding sleep problems and mental disorders among young adults. Methods: Our sample consists of 469 young adults, aged 18–29 years, from the Mental Health in Early Adulthood Study in Finland (MEAF) conducted in 2003–2005. Chronotype was based on the assessment of one question that was asked first in 2000–2001 and the second time in 2003–2005. Those 73 participants who changed their chronotype were excluded from the main analysis, but separate analyses were performed with this group. Results: Concerning sleep, E-types reported higher dependency on alarm clocks (p < 0.001), and E-types and I-types had more problems in feeling refreshed after waking up (p < 0.0001 and p < 0.05 respectively) than M-types. Regarding mental health, E-types and I-types had lower odds for any lifetime DSM-IV Axis I disorder (p < 0.05 and p < 0.01 respectively) than M-types. Conclusions: Our results are in line with previous findings that those with the diurnal preference towards eveningness have more frequently three or more lifetime mental disorders, more sleeping problems, more seasonal variation in mood and behaviour, and more burnout compared with those with the diurnal preference towards morningness.     

Compulsory admission is associated with an increased risk of readmission in patients with schizophrenia: a 7-year,population-based,retrospective cohort study

Purpose

The aim of this study was to assess the risk of psychiatric readmission in patients with schizophrenia, compare it between patients prescribed compulsory admission and those consenting to voluntary admission, and determine risk factors for psychiatric readmission.

Methods

This 7-year (2007–2013), population-based, cohort study retrospectively compared data of 2038 schizophrenic inpatients who initially underwent compulsory admission (the CA group) and of 8152 matched controls with schizophrenia who initially underwent voluntary admission (the VA group).

Results

During the study period, there were 1204 and 3806 readmissions in the CA and VA groups, respectively. Compared with the VA group, the CA group was associated with a greater risk of psychiatric readmission [adjusted hazard ratio (AHR) = 1.765; 95% confidence interval (CI) 1.389–2.243; P < 0.001]. Stratified analyses showed that the CA group was associated with a higher risk of subsequent compulsory (AHR = 1.307; 95% CI 1.029–1.661; P < 0.001) and voluntary (AHR = 1.801; 95% CI 1.417–2.289; P < 0.001) readmissions compared to the VA group. Sensitivity analyses, after excluding data from the first year of observation, also provided significant findings with respect to compulsory and voluntary readmissions. Kaplan–Meier curves revealed that cumulative survival rates of psychiatric readmissions, compulsory and voluntary readmissions were significantly lower in the CA group than in the VA group among patients with schizophrenia (log-rank test, P < 0.001).

Conclusions

CA was associated with higher subsequent psychiatric readmissions, compulsory, and voluntary readmissions. Clinicians would need to focus on patients undergoing CAs to reduce readmissions.

     

Adjustments in the force–frequency relationship during passive and exercise‐induced hyperthermia

Introduction: We examined the extent to which fatiguing cycling exercise in the heat influences contractile function in modulating the force–frequency relationship. Methods: Before (∽37.0°C) and after (∽38.5°C) exercise (ExH) and passive (PaH) hyperthermia, an 8‐s train of stimulation at 10, 20, 50, and 100 Hz (2 s per frequency) and a potentiated twitch were evoked on the relaxed knee extensors using percutaneous stimulation. Results: ExH and PaH produced a decrease in the 20:50 Hz force ratio, indicative of low‐frequency fatigue (P < 0.01). This adjustment was more pronounced after ExH than PaH (P < 0.01). A rightward displacement in the force–frequency relationship occurred after ExH and PaH (P < 0.05) and was exacerbated by ExH (P < 0.05). Peak twitch force also decreased after ExH (P < 0.05). Conclusions: ExH reduces force summation due to development of skeletal muscle fatigue, exacerbating the shift in force–frequency to the right relative to PaH. Muscle Nerve 50 : 822–829, 2014     

Adolescent Obesity and School Performance and Perceptions of the School Environment Among Minnesota High School Students

This study examined associations between adolescent obesity and school performance and perceptions of the social environment and safety at school. Data are from the Minnesota Student Survey (n = 87,468 students) which was administered statewide in the spring of 2007. Student’s responses to questions about grades achieved in school, skipping school, future school plans, and perceptions of the social environment and safety in school were analyzed in relation to their weight status using logistic regression and general linear modeling. Overweight and obese adolescents were significantly less likely to plan to go to college; more likely to report skipping school because of fears of safety, lower academic grades, an individualized education plan, and negative perceptions about the social environment and safety in school than non-overweight students (all p < .001). Study findings can help guide school and other health professionals’ assessment and intervention strategies to improve the quality of life for overweight and obese youth.     

Biochemical and molecular effects of chronic haloperidol administration on brain and muscle mitochondria of rats

The objectives of the current study were to evaluate (1) the respiratory rates and enzyme activities of brain and muscle mitochondria from rats chronically treated with haloperidol, (2) the protective role of dopamine (DA) D-1 (SKF38393) and D-2 (quinpirole) receptor agonists, and (3) the effect of haloperidol on the mitochondrial DNA (mtDNA) and protein synthesis. Thirty male Sprague-Dawley rats were subdivided into the following five groups: controls, haloperidol, haloperidol plus SKF38393, haloperidol plus quinpirole, and haloperidol plus SKF38393 and quinpirole. We compared the respiratory rates and enzymatic activities of brain and muscle mitochondria from controls with other groups. We finally analyzed the mitochondrial protein synthesis and mtDNA alterations (deletions, point mutations, and depletion) in two rats from each group. In brain but not in muscle from haloperidol-treated rats, we found a decrease of oxygen consumption rates using glutamate plus malate (−68 ± 35%, P < 0.05) and succinate (−78 ± 20%, P < 0.05) as substrates as well as low complex I, II, and V activities (−35 ± 15%, P < 0.05; −54 ± 13%, P < 0.05; and −60 ± 33%, P < 0.01; respectively). The administration of SKF38393 alone or together with quinpirole prevented most of haloperidol-induced effects, whereas the protective effects of quinpirole alone were lower. Brain mitochondrial protein synthesis was decreased in haloperidol-treated rats and was not prevented by SKF38393, quinpirole, or both. We did not find mtDNA abnormalities in brain or muscle mitochondria from haloperidol-treated rats. Chronic administration of haloperidol in rats is associated with a nonspecific deleterious effect in the activity of electron transport chain of brain, and this effect is only partially prevented by DA D-1 agonists. These results suggest that other mechanisms different from DA receptors pathway can contribute to the expression of behavioral supersensitivity. J. Neurosci. Res. 53:475–481, 1998. © 1998 Wiley-Liss, Inc.     

Parkinson's disease patients first treated at age 75 years or older: A comparative study

BackgroundParkinson's disease (PD) first diagnosed at older age reportedly has different clinical characteristics and survival rates than when it is first diagnosed at younger age. We compared these features among PD patients who initiated anti-parkinsonian drugs at age 75–85 years (elderly) with those who started treatment at age 50–74 years (younger).MethodsWe used a population-based cohort of 4449 incident cases of PD patients aged 50–85 at treatment initiation, based on a pharmacy registry of Maccabi Health Maintenance Organization, with definite/probable/possible certainty of having PD. Mean follow-up was 3.9 ± 2.6 years. The two age groups were compared for time/risk to levodopa and to death, using Kaplan–Meier curves and Cox regression. Gender-specific standardized mortality rates (SMRs) accounting for Israeli death rates were also compared.ResultsOne-half of the entire cohort (n = 2148) were elderly (>75 years) and more likely to be given levodopa (Hazard Rate (HR) = 1.48, P < 0.05), had a significantly higher frequency of comorbidities (e.g., heart disease, hypertension and cancer), and had a 3-fold increased risk to die (HR = 2.97, P < 0.05) within the same follow-up time as the youngers. Accounting for the general Israeli population death rates, female PD patients had a significantly lower risk to die compared to males especially females who were elderly at treatment initiation (SMR = 1.53 for females vs. 1.73 for males, P < 0.05).ConclusionsPD patients first diagnosed and treated at >74 years of age comprise a unique cluster for inclusion into drugs studies, mortality risk analyses and for projection of disease burden.     

Attempted suicide rates and trends during a period of severe economic recession in Helsinki, 1989-1997

Background: This study investigated attempted suicide trends during a deep economic recession in the 1990s in a well-defined urban catchment area. Methods: The data covered every suicide attempt treated in health care during sample periods in 1989–1997 in Helsinki, Finland. Annual rates were estimated, 3-year moving averages for trends calculated, and significances tested. Results: The overall attempted suicide rate remained stable over the 9-year study period. Against expectations, male rates decreased significantly (P < 0.01), especially among those aged 15–34. There was a convergence of female and male rates, although male rates remained higher. The proportion of poisonings as method increased (P < 0.01). Conclusions: Despite the deep economic recession, with rapidly rising unemployment attempted suicide rates remained unexpectedly stable. The total attempted suicide rate did not increase as might have been anticipated, and the male rate even decreased. Accepted: 24 April 2001     

Mechanomyographic and electromyographic responses to eccentric and concentric isokinetic muscle actions of the biceps brachii

The purpose of the present investigation was to examine the effects of forearm angular velocity on the mechanomyographic (MMG) and electromyographic (EMG) responses to eccentric and concentric isokinetic muscle actions. Ten adult male volunteers (mean ± SD age = 23 ± 2 years) performed maximal eccentric and concentric muscle actions of the forearm flexors at 30°, 90°, and 150° s⁻¹. There was no significant (P > 0.05) velocity-related change in peak torque (PT) for the eccentric muscle actions, but there was a significant (P < 0.05) decrease in PT for the concentric muscle actions. For the eccentric and concentric muscle actions, there was a significant (P < 0.05) velocity-related increase in MMG amplitude. There was no significant (P < 0.05) change in EMG amplitude across velocity for the eccentric or concentric muscle actions. The results indicated velocity-related dissociations among the PT, MMG, and EMG responses to maximal eccentric and concentric isokinetic muscle actions. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21: 1438–1444, 1998     

Association of muscle strength and electrophysiological measures of reinnervation in diabetic neuropathy

Motor function was assessed in 34 non-insulin-dependent and 19 insulin-dependent diabetic patients with macroelectromyography and isokinetic dynamometry. Fiber density (FD) and the amplitude of the macro motor unit potential (macro MUP) of the anterior tibial and lateral vastus muscles were obtained and maximal isokinetic strength of the ankle and knee extensors were determined. All patients underwent standardized clinical examination including a neurological disability score (NDS), quantitative sensory examination, and conventional motor nerve conduction studies. The amplitude of the macro MUP and FD of the anterior tibial muscle were increased in neuropathic patients without weakness (P < 0.05) and further increased in neuropathic patients with weakness (P < 0.05). The NDS was related to the FD and the amplitude of the macro MUP for the anterior tibial and lateral vastus muscle [r = 0.55–0.75 (P < 0.005)]. Muscle strength of ankle and knee extensors correlated with the FD [r = −0.69 (P < 0.0001) and r = −0.58 (P < 0.001), respectively] and with the amplitude of the macro MUP of the two muscles [r = −0.63 (P < 0.0001) and r = −0.37 (P < 0.05), respectively]. Our findings support the hypothesis that loss of muscle strength in diabetic patients is due to incomplete reinnervation following axonal loss. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21: 1647–1654, 1998     

Effects of dehydration and salt-loading on hypothalamic vasopressin mRNA level in male and female rats

Experiments were carried out on 9- to 11-week-old male and female Sprague-Dawley rats. Dot-blot analysis and 3′-end digoxigenin-labeled 26mer oligonucleotide probe were used in the investigation of vasopressin (AVP) mRNA level in the hypothalamus of male and female rats. The normal hypothalamic AVP-mRNA level in males was 48% higher than that in females (P < 0.05). Plasma osmolality was also higher in males than in females (P < 0.05). In dehydrated rats, the hypothalamic AVP-mRNA level was 2.47 and 1.98 times in females (P < 0.001) and males (P < 0.01), respectively, as much as in their normal controls; the difference in hypothalamic AVP-mRNA level between dehydrated females and males was statistically insignificant. Plasma osmolality was higher in dehydrated females than in dehydrated males (P < 0.01). In salt-loaded rats, hypothalamic AVP-mRNA level was 2.47 and 2.17 times in females (P < 0.001) and males (P < 0.01), respectively, as much as in their controls. The difference in hypothalamic AVP-mRNA level between salt-loaded males and females was not statistically significant. Plasma osmolality in salt-loaded females was also higher than that in salt-loaded males (P < 0.001). These findings indicate that there is sex difference in hypothalamic AVP mRNA level and plasma osmolality under normal conditions; during dehydration and salt-loading AVP mRNA level increases and the difference in AVP mRNA level between males and females becomes insignificant.     

Time trends and disparities in anxiety among adolescents, 2012–2018

Purpose

Prior studies have been inconclusive in documenting whether the prevalence of adolescent anxiety is increasing, given sampling and measurement limitations. This study adds new information on recent time trends in anxiety prevalence, specifically investigating trends among previously unexamined sociodemographic subgroups.

Methods

Weighted data of 37,360 youth respondents (51.1% female, 71.8% White, 91.3% heterosexual, 99.2% cisgender) from the 2012–2018 Dane County Youth Assessment, a county-wide survey administered to youth in participating school districts, were analyzed to estimate time trends in anxiety prevalence among the whole sample and by sociodemographic subgroups.

Results

The prevalence of youth meeting anxiety-screening criteria increased from 34.1% (95% CI 33.4–34.9) in 2012 to 44% (95% CI 43.2–44.7) in 2018 (OR for trend = 1.07, P for trend < 0.001). The trend remained significant after adjusting for known confounds (AOR for trend = 1.07, P for trend < 0.001). Anxiety increased significantly for several subgroups and widening disparities were documented among females relative to males (P < 0.001), and sexual minority youth relative to heterosexual youth (P = 0.003). In addition, Black youth did not increase at the same swift rate as White youth over the study period (P < 0.001).

Conclusion

This study reports recent data on anxiety time trends and finds that among a geographically representative sample of adolescents, anxiety prevalence is rising. Findings provide new evidence documenting increased anxiety prevalence among sexual minority youth relative to their peers. Results highlight the need to bolster public health interventions focused on adolescent mental health, with tailored interventions for vulnerable groups.