Inflammatory pseudotumour of the paranasal sinuses--a case report

Inflammatory pseudotumour represents benign non-specific granulation, and is uncommon in the head-and-neck region, particularly in the paranasal sinuses. We present herein the case of a 63-year-old woman with inflammatory pseudotumour of the paranasal sinuses. Physical examination and computed tomography revealed a mass in the bilateral nasal cavity and paranasal sinuses with extension to bilateral orbits. Multiple intranasal biopsies revealed marked lymphoplasmatic infiltration and myofibroblastic proliferation with hyalinisation. Systemic steroid therapy was selected and was very effective. The lesion has shown no evidence of enlargement for more than 1 year. The difficulties in establishing the clinico-pathological diagnosis and treatment are discussed.     

Solitary fibrous tumour of the nasal cavity and paranasal sinuses

OBJECTIVE: Solitary fibrous tumour (SFT) is an uncommon unilateral benign lesion that usually arises from the pleura. Recently, SFT has been described in many other locations, such as the mediastinum, head and neck, orbit and urogenital system. To date, only 21 cases of SFT arising from the nasal cavity and paranasal sinuses have been reported in the literature. MATERIAL AND METHODS: We describe a case of SFT localized in the right nasal cavity with extension to the right ethmoid and sphenoid sinuses in a 43-year-old man who presented with a 6-month history of unilateral right-sided nasal obstruction, rhinorrhoea and recurrent epistaxis. RESULTS: CT showed a large mass arising from the right anterior ethmoid and sphenoid sinuses. Histopathologically, the lesion consisted of a non-encapsulated mass with spindle-shaped cells within a collagenous stroma. Definitive diagnosis was obtained by means of immunohistochemical analysis, which showed vimentin and CD34 cells. CONCLUSION: The tumour was removed by endoscopic sinus surgery, and the patient remained free of tumour after 12 months of follow-up.     

鼻腔鼻窦恶性肿瘤临床治疗分析

鼻腔鼻窦恶性肿瘤约占全身肿瘤的0．5％,本文就64例鼻腔鼻窦恶性肿瘤单纯或综合治疗下的局部控制及5年生存情况进行分析。结果：本组总局部控制率为70．3％,Ⅱ、Ⅲ、Ⅳ期的控制率分别为76．5％、72．7％和70％。手术标本切缘阴性局部控制率为73．8％,而阳性则为33．3％。5年生存率为47．8％,综合治疗的5年生存率高于单一治疗,本组资料显示S＋R和A＋R＋S较高,分别为61．1％和62．0％,而S和R则较低（33．3％和28．6％,P＜0．01）。标本切缘、颈淋巴结转移及T分期,治疗方式均影响预后,综合治疗的疗效好,早期发现及较彻底切除是获得良好治疗效果的关键。     

原发性鼻腔-鼻窦砂粒体型脑膜瘤1例报道并文献复习

目的 通过报道1例原发于鼻腔-鼻窦砂粒体型脑膜瘤患者的临床资料及相关文献复习,以提高临床医师对该病的认识及诊疗水平.方法 患者,女,50岁,因"渐进性右侧鼻塞1年余"入院.术前影像学检查提示右侧鼻腔及筛窦内不规则占位性病变,遂在全麻鼻内镜下行右侧鼻腔筛窦肿物切除术.结果 肿物完全切除,术后病理及免疫组化确诊为砂粒体型脑...     

Glomangioma of the nasal cavity and paranasal sinuses

The glomangioma, a benign vascular tumour, derived from the cutaneous glomus bodies, should not be confused with paragangliomas, which are occasionally also referred to as glomus tumours. Up to now, only eleven cases of a glomangioma of the nasal cavity and the paranasal sinuses have been published. We report the case of a patient with a glomangioma of the ethmoidal aircell system. The tumour was completely removed under endoscopic-microscopic vision via endonasal access. A tumour recurrence was not observed over a period of eighteen months. The clinical signs, diagnosis, therapy and histological features will be discussed with reference to the literature.     

Microsurgery of the nasal cavity and paranasal sinuses

Out of a total of 295 cases in which endonasal microsurgery of the nasal cavity and the paranasal sinuses was performed, 221 were submitted to a detailed analysis. Compared with transfacial sinus surgery, the rate of complications was significantly lower. Further advantages of the transnasal microsurgical technique are better functional results, considerably fewer complaints during the postoperative period, and a reduced duration of hospitalization.     

A rare case of malignant lymphoma of the nasal cavity and paranasal sinuses

The head and neck region is one of the most common sites of extranodal non-Hodgkin's lymphoma, but it is an infrequent tumor at the nasal cavity and paranasal sinuses site, representing no more than 5.8-8 percent of the entire malignant tumors in this localization and 0.3-2 percent of all extranodal lymphomas. A case of non-Hodgkin's lymphoma in fifty seven years-old man is reported. The patient has been admitted for curing because of returning during few last years nose bleeding, cured symptomatically. From last few weeks the wall protrusion of the right side of nose. Clinical and radiological examinations have found large pathological changes of nasal cavity and paranasal sinuses. Histological examination has shown the presence of lymphoma malignum. They also haven't found other neoplasm focuses. The sick has been curing by Co-60 radiation with a perfect effects. Now, after a years observation they haven't found a sick returning.     

Glomangioma in the nasal cavity and paranasal sinuses

The glomangioma is a hyperplastic lesion of the glomus body. This uncommon tumor is seldom located in the nasal cavity or paranasal sinuses. We present what is to our knowledge the eleventh documented case of an intranasal glomangioma. The differential diagnosis of this lesion, its symptoms, pathogenesis and therapy are discussed. Complete excision is normally curative for this tumor.     

乳腺癌鼻腔鼻窦颅底转移1例

目的探讨乳腺癌鼻腔鼻窦颅底转移性病变的临床诊治。方法回顾性分析收治的1例乳腺癌鼻腔鼻窦颅底转移性病变患者的临床病例资料,对该疾病的临床特点、诊断及治疗进行讨论。结果本例患者术前行CT、MRI检查示蝶窦内可见软组织影并骨质破坏,并给予抗感染等治疗,症状未见明显好转,患者在全麻鼻内镜下行鼻窦肿物切除术,术后病理结果示鼻窦肿物为乳腺癌转移性病变,建议患者行放射及化学治疗。结论乳腺癌是女性常见的恶性肿瘤之一,发生头颈部转移临床并不常见,尤其发生鼻腔鼻窦颅底转移极为罕见。因此需结合病史、临床症状、体格检查及相应的辅助检查等,做出正确的临床诊断并制定相应的治疗方案,防止鼻腔鼻窦颅底转移性病变的误诊漏诊。     

Extranasopharyngeal angiofibroma of the nasal cavity and paranasal sinuses

BACKGROUND: Angiofibromas commonly arise in the nasopharynx in young male patients. Diagnosis is widely based on radiographic imaging to avoid ill-advised biopsy which may result in brisk bleeding. This study was undertaken to evaluate the incidence, clinical features and complications that may occur during the process of diagnosis and surgical therapy of angiofibromas outside the nasopharynx. METHODS AND PATIENTS: Case report of a 13-year-old female patient and review of the literature. RESULTS: Our patient received multi-agent chemotherapy elsewhere due to a misdiagnosed angiofibroma. Computed Tomography (CT) revealed a maxillary tumor which was repeatedly biopsied. Hypervascularity was excluded by arteriography and the lesion removed after lateral rhinotomy. The data of 42 patients were analyzed including our own case. 32 patients were male, 10 female. The majority became symptomatic aged 19 years or younger (71.4 %). The maxilla was most commonly affected (38 %), less frequently the ethmoid, nasal cavity or septum, beside others. In 38 patients, symptoms developed within 12 months or less (average: 8.5 months). Epistaxis, nasal obstruction and facial swelling were reported for most patients. Brisk bleeding occurred in 10 patients during tumor removal and resulted from biopsies in 11 of 20 patients. Angiography detected hypervascularity in 3 of 4 patients. There was no case with lethal outcome. CONCLUSION: Extranasopharyngeal angiofibromas of the nasal cavity or paranasal sinuses should be included in the differential diagnosis of nasal tumors. Compared to nasopharyngeal angiofibromas, more female patients are involved, symptoms develop more quickly but hypervascularity is less common. Signs of questionable hypervascularity in Computed Tomography and Magnetic Resonance Imaging (MRI) should indicate arteriography prior to surgical procedures. Preoperative embolization of hypervascular lesions during arteriography will reduce the risk of brisk bleeding during biopsy or surgical tumor removal.