凤仙透骨草的化学成分

目的:研究凤仙花科凤仙花属植物凤仙花干燥茎中的化学成分.方法:利用硅胶,Sephadex LH-20及大孔吸附树脂等色谱法分离凤仙透骨草的化学成分,用波谱方法鉴定其结构.结果:从凤仙透骨草中分离并鉴定了7个化合物,分别鉴定为2-甲氧基-1,4-萘醌(1)、香草酸(2)、七叶内酯(3)、原儿茶酸(4)、芦丁(5)、大豆脑苷I(6)、1,2,4-三羟基萘-1,4-双-β-D-吡喃葡萄糖苷(7).结论:化合物2～7为首次从该属植物中得到.     

维吾尔药指甲花和凤仙花的定性鉴别研究

目的建立维吾尔药指甲花和凤仙花药材的鉴别方法。方法采用薄层色谱(TLC)法及高效液相色谱(HPLC)指纹图谱法,观察其主要特征化合物的差别。结果所建立的TLC法可初步鉴别指甲花和凤仙花;HPLC法测定结果表明,指甲花和凤仙花的化学成分存在一定的相似性,但又各有其特异性。结论 TLC法快速,HPLC法准确,为维吾尔药指甲花的质量控制提供了鉴别依据。     

中药急性子化学成分及药理作用的研究进展

急性子为凤仙花科凤仙花属植物凤仙花(Impatiens bal saminaL.)的干燥成熟种子,始载于《救荒本草》,为我国传统中药之一.药材呈椭圆形、扁圆形或扁卵圆形,夏、秋季果实成熟而未开裂时采收,晒干,搓出种子,除去果皮及杂质而得,我国大部分地区均有分布,且资源丰富.其味微苦,性辛、温;有小毒.归肺、肝经.具有破血、软坚、消积的功效[1],临床上主要用于避孕、终止早孕、癌症、肿瘤、闭经、骨质增生等的治疗[2-5].目前国内外对急性子的研究主要是对急性子化学成分及其药理作用的研究,笔者就近年来国内外对急性子的相关研究报道综述如下.     

太子参研究概况

本文从太子参的化学成分和药理研究等方面综合叙述了其研究概况。太子参的化学成分包括:甙类,糖类,氨基酸类,油脂类,磷脂类,环肽类,挥发油类,脂肪酸类等。具有增强肌体作用及免疫促进等作用。其化学成分及药理作用的深入研究对太子参的开发将提供有价值的资料。     

大血藤化学成分提取方法和药理作用的研究进展

目的：综述中药大血藤的化学成分提取方法及药理作用情况。方法对国内大血藤的化学成分、药理作用方面的文献进行总结。结果大血藤主要化学成分有酚酸类、蒽醌类、黄酮类、总皂苷、鞣质类等;药理作用有抗菌、抗病毒、消炎、抗肿瘤等。结论大血藤中化学成分的提取与测定方法较成熟、临床应用广泛,具有很好的应用前景。     

土贝母的化学成分及药理作用研究进展

土贝母中含有皂苷类、有机酸类、甾醇类、生物碱类等化学成分,药理作用为抗病毒、抗癌、抑制免疫、杀精等。通过对土贝母的化学成分及药理作用概况进行综述,以期为该药材的进一步开发研究提供参考。     

荞麦属植物化学成分及生物活性研究进展

目的总结荞麦属植物化学成分及生物活性的最新研究进展,为荞麦属植物的研究开发提供参考。方法查阅国内外文献资料进行整理和归纳。结果荞麦属植物主要含有黄酮类、缩合鞣质类、酚类、脂肪酸类、三萜、甾体类、环醇类等化学成分;具有抗肿瘤、抗氧化、抗菌、抗炎、抗过敏等多种生物活性。结论荞麦属植物具有较高的开发价值,其化学成分及生物活性有待深入研究。     

西藏胡黄连的化学成分研究进展

西藏胡黄连的化学成分按化学结构分主要有环烯醚萜类、葫芦素类、苯乙醇糖苷类和酚苷类,其中的苯乙醇糖苷类化学成分在印度胡黄连中较为少见,另外还含有少量的甘露醇、胡黄连醇、胡黄连甾醇、香荚兰乙酮及酚酸等.本文综述西藏胡黄连的化学成分研究进展.     

地锦属植物的化学成分及药理研究进展

地锦属Parthenocissus Planch.植物含有多酚类、黄酮类、酚酸类、脂肪酸类及糖苷类等多种类型化学成分,具有抗氧化、抑菌、抗炎、抗血栓、调节血脂及降血糖等多药理活性,该属植物在药品、保健品和化妆品等方面有较大开发潜力。本文对地锦属植物化学成分和药理活性的研究进展进行系统综述,以期为该属植物的进一步研究和开发利用提供科学依据。     

忍冬的化学成分研究进展

忍冬是我国重要的药用植物,其藤、叶、花均可入药。忍冬的化学成分主要包括以绿原酸为代表的有机酸类、黄酮类、环烯醚萜苷类、三萜及三萜皂苷类、挥发油类等,还有单萜环苷类、倍半萜类及其他类化合物。对忍冬各个药用部位的化学成分进行综述,为其进一步研究开发提供参考。     

Two new flavone glycosides from the seeds of Impatiens balsamina L

Two new flavone glycosides were isolated from the seeds of Impatiens balsamina L. and their structures were determined as quercetin-3-O-[α-L-rhamnose-(1 → 2)-β-d-glucopyranosyl]-5-O-β-D-glucopyranoside (1), and quercetin-3-O-[(6'-O-caffeoyl)-α-L-rhamnose-(1 → 2)-β-D-glucopyranosyl]-5-O-β-D-glucopyranoside (2) on the basis of various spectral and chemical studies.     

凤仙花色素指甲油的研究

目的 将从凤仙花中提取得到的天然花色素充当显色剂,用于制作指甲油.方法 从凤仙花有效部位中提取色素,配以一定的辅助剂,寻找各成分之间的最佳比例并制成指甲油.结果 当各成分组成为凤仙花色素干燥粉末4%,PU树脂91%,水性润湿剂0.4%,去离子水2%,水性流平剂0.4%,水性消泡剂0.2%,成膜助剂2%时,得到的指甲油最为理想.结论 初步得到了较为理想的指甲油.     

Naphthoquinone Formation in Cell Cultures of Impatiens balsamina

Induction of naphthoquinone formation in Impatiens balsamina cell cultures was achieved by using parent plants yielding high levels of 2-methoxy-1,4-naphthoquinone as initiated explants. The cell culture with red-yellowish color was established in B5 medium supplemented with 0.1 mg/L 2,4-dichlorophenoxyacetic acid (2,4-D) and 1.0 mg/L 6-benzylaminopurine (BA). The cell cultures were capable of producing two naphthoquinones, lawsone, and an unknown, which was more polar than lawsone. The time-course of growth and lawsone production in I. balsamina cell culture were also established.     

Cyclooxygenase-2 inhibitory 1,4-naphthoquinones from Impatiens balsamina L

Significant selective cyclooxygenase-2 (COX-2) inhibitory activities were observed for two new 1,4-naphthoquinone sodium salts, sodium 3-hydroxide-2[[sodium 3-hydroxide-1,4-dioxo(2-naphthyl)]ethyl]naphthalene-1,4-dione (impatienolate) (1) and sodium 2-hydroxide-3-(2-hydroxyethyl)naphthalene-1,4-dione (balsaminolate) (2), which were isolated from the corolla of Impatiens balsamina L. (Balsaminaceae). Their structures were elucidated by spectral techniques. Our results offer evidence supporting the use of I. balsamina L. to treat articular rheumatism, pain, and swelling.     

散沫花、凤仙花的化学成分及其在化妆品中的应用现状

散沫花和风仙花均俗称为指甲花,两者均有染色作用,但两者原植物科属不同,化学成分和药理作用也大不一致。现就两者的研究现状,包括本草考证、化学成分、药理作用及在化妆品中的应用及其安全性进行概述。     

中药透骨草的形态组织学研究

目前中药应用的透骨草主要有五种——大戟科植物地构叶Speranskia tuberculata(Bunge)Baill.的地上部分、凤仙花科植物凤仙花Impatiens balsamlna L.的地上茎、紫葳科植物角蒿Incarvillea sinensis Lam.的地上部分、毛茛科植物黄花铁线莲Clematis intricata Bunge的地上部分(黄花铁线透骨草)和细叶铁线莲C.aethusaefolia Turcz.的地上部分(细叶铁线透骨草)的生药形态、组织构造及粉末特征。     

A new biscoumarin from Impatiens balsamina root cultures

A new biscoumarin, 4,4'-biisofraxidin has been isolated from the root cultures of Impatiens balsamina (Balsaminaceae). The structure was elucidated by 1D and 2D NMR techniques.     

HPLC法测定不同产地凤仙花饮片中山奈素的含量

目的:建立测定不同产地凤仙花饮片中山奈素含量的方法。方法:采用高效液相色谱法。色谱柱为Diamonsil C18(250mm×4.6 mm,5μm),流动相为乙腈-0.2%磷酸溶液(35∶65,V/V),检测波长为360 nm,流速为1.0 ml/min,柱温为40℃,进样量为5μl。结果:山奈素的质量浓度在8.16⁸1.60μg/ml范围内与峰面积积分值呈良好线性关系(r=0.999 6);精密度、重复性、稳定性试验的RSD<2%;平均加样回收率为99.68%,RSD=1.9%(n=9)。结论:湖北宜昌所产的凤仙花饮片中的山奈素含量最高。该方法操作简便,结果准确、可靠,可用于凤仙花饮片的质量控制。     

Preventive effects of Impatiens balsamina on the hen egg-white lysozyme (HEL)-induced decrease in blood flow

Monitoring the blood flow of unanesthesized mice was found to be a reliable and effective method for studying their anaphylactic responses, in addition to the known method of monitoring blood pressure. Hen egg-white lysozyme (HEL)-specific anaphylaxis in mice was estimated by monitoring the decrease in blood flow with a Doppler blood flow meter. This method is convenient for searching for both anaphylaxis and anti-anaphylactic substances from natural products. Using this system, we estimated the anti-anaphylactic effects of the 35% ethanol extract (IB) of petals of Impatiens balsamina L., as well as those of anti-allergic agents currently used. Kaempferol 3-rutinoside and lawsone from IB significantly inhibited the decrease of blood flow. We also found that platelet-activating factor (PAF) and serotonin participate in decreasing the blood flow, but histamine does not.     

Simultaneous qualification and quantification of baccharane glycosides in Impatientis Semen by HPLC-ESI-MSD and HPLC-ELSD

This study presents a high performance liquid chromatography (HPLC) with electrospray ionization mass spectrometric detection (ESI-MSD) and evaporative light scattering detection (ELSD) method for the simultaneous qualification and quantification of eight major baccharane glycosides, namely hosenlosides A, B, C, F, G, K, L, and M in Impatientis Semen, a Chinese herbal medicine derived from the seeds of Impatiens balsamina L. In order to achieve optimum performance, several extraction parameters (including extraction solvent, extraction mode, extraction time) were optimized. The baccharane glycosides were separated on a Shim-pack CLC-ODS column with gradient elution of water and methanol. Temperature for the ELSD drift tube was set at 98°C and the nitrogen flow rate was 2.7l/min. The unambiguous identities of the analytes were realized by comparing retention times and mass data with those of reference compounds. The developed method was fully validated in terms of linearity, sensitivity, precision, repeatability, recovery as well as robustness, and subsequently applied to evaluate the quality of 14 batches of Impatientis Semen commercial samples from different collections.