共查询到20条相似文献,搜索用时 31 毫秒
1.
Charles F. Barish Douglas Drossman John F. Johanson Ryuji Ueno 《Digestive diseases and sciences》2010,55(4):1090-1097
Aims
The aim of this study is to assess the efficacy and safety of lubiprostone in adults with chronic constipation. 相似文献2.
Vito D Corleto Stefano Gambardella Francesca Gullotta Maria R D'Apice Matteo Piciucchi Elena Galli Vincenzina Lucidi Giuseppe Novelli Gianfranco Delle Fave 《BMC gastroenterology》2010,10(1):119
Background
acute recurrent pancreatitis is a complex multigenic disease, the diagnosis is even more difficult when this disease develops in a child. 相似文献3.
Taijiro Wake Ryosuke Tateishi Makoto Moriyama Tsuyoshi Fukumoto Tomoharu Yamada Ryo Nakagomi Takuma Nakatsuka Masaya Sato Tatsuya Minami Koji Uchino Hayato Nakagawa Shuichiro Shiina Kazuhiko Koike Mitsuhiro Fujishiro 《Hepatology research》2023,53(7):675-680
Aim
The aim of this study was to evaluate the effects of steroids on ischemic complications after radiofrequency ablation.Methods
A total of 58 patients with ischemic complications were divided into two groups according to corticosteroid use or non-use.Results
A total of 13 patients who were administered steroids had a shorter duration of fever than those who were not administered steroids (median 6.0 vs. 2.0 days; p < 0.001). Linear regression analysis showed that steroid administration was associated with a reduction of 3.9 days in the duration of fever (p = 0.008).Conclusions
Steroid administration for ischemic complications after radiofrequency ablation may reduce the risk of fatal outcomes by blocking systemic inflammatory reactions. 相似文献4.
Hsu-Heng Yen Yang-Yuan Chen Chia-Wei Yang Maw-Soan Soon 《Digestive diseases and sciences》2010,55(12):3473-3478
Background
Jejunal diverticular disease is a rare cause of gastrointestinal bleeding. The reported incidence of this disease is low in the studies of double-balloon enteroscopy. 相似文献5.
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Background
Polysaccharide pneumococcal vaccine is recommended for use in HIV-infected adults in Brazil but there is uncertainty about its effectiveness in this patient population. 相似文献7.
Ilja Tachecí Jaroslav Květina Jan Bureš Jan Österreicher Martin Kuneš Jaroslav Pejchal Stanislav Rejchrt Stanislav Špelda Marcela Kopáčová 《Digestive diseases and sciences》2010,55(9):2471-2477
Aim
The aim of this study is to evaluate the diagnostic yield of capsule endoscopy in nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy in pigs. 相似文献8.
9.
Sequist TD Cullen T Bernard K Shaykevich S Orav EJ Ayanian JZ 《Journal of general internal medicine》2011,26(5):480-486
BACKGROUND
Although Native Americans experience substantial disparities in health outcomes, little information is available regarding healthcare delivery for this population. 相似文献10.
Arina Miyoshi So Nagai Masamitsu Takeda Takuma Kondo Hiroshi Nomoto Hiraku Kameda Amiko Hirai Kyuyong Cho Kimihiko Kimachi Chikara Shimizu Tatsuya Atsumi Hideaki Miyoshi 《Journal of diabetes investigation.》2013,4(3):326-329
Aims/Introduction
Polycystic ovary syndrome (PCOS) is a heterogeneous disorder including polycystic ovary morphology (PCOM), ovulatory dysfunction and hyperandrogenism. PCOS is frequently associated with type 2 diabetes mellitus; however, it is unknown whether PCOM and PCOS are prevalent in Japanese patients with type 1 diabetes mellitus. The purpose of our study was to determine the frequency of PCOM and PCOS in women with type 1 diabetes mellitus.Materials and Methods
We evaluated clinical, hormonal and ovarian ultrasound data from 21 type 1 diabetes mellitus patients whose average glycated hemoglobin levels were 7.9 ± 1.5%.Results
Ultrasound identified PCOM in 11 patients (52.4%) and these patients also had higher levels of the androgen dehydroepiandrosterone sulfate (DHEA‐S) than those without PCOM (P < 0.05). Of the patients with PCOM, five presented menstrual irregularities (45.5%) and three met the Japanese criteria for PCOS (27.2%); whereas all patients without PCOM had a normal menstrual cycle (P < 0.05).Conclusions
Japanese premenopausal women with type 1 diabetes mellitus had a high frequency of PCOM as well as PCOS. This is the first research of this area carried out in an Asian population. 相似文献11.
Aims
Intestinal tuberculosis is not uncommon in developing countries. The diagnosis of this disease is quite difficult. The purpose of our research was to recall the clinical, colonoscopic, and histopathological features of this disease. 相似文献12.
Borasio P Gisabella M Billé A Righi L Longo M Tampellini M Ardissone F 《International journal of colorectal disease》2011,26(2):183-190
Purpose
The aim of this study is to investigate clinicopathologic characteristics and to identify prognostic factors in patients undergoing pulmonary metastasectomy for colorectal carcinoma. 相似文献13.
Effects of comorbid substance use disorders on outcomes in a Housing First intervention for homeless people with mental illness
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Karen Urbanoski Scott Veldhuizen Michael Krausz Christian Schutz Julian M. Somers Maritt Kirst Marie‐Josée Fleury Vicky Stergiopoulos Michelle Patterson Verena Strehlau Paula Goering 《Addiction (Abingdon, England)》2018,113(1):137-145
Background and Aims
Evidence supports the effectiveness of Housing First (HF) programmes for people who are experiencing homelessness and mental illness; however, questions remain about its use in people with comorbid substance use disorders (SUD). The aim of this project was to test whether SUD modifies the effectiveness of an HF intervention.Design
Secondary analysis of data from a randomized controlled trial of HF versus treatment‐as‐usual (TAU) with 24‐month follow‐up, comparing those with and without SUD at trial entry.Setting
Vancouver, Toronto, Winnipeg, Moncton and Montreal, Canada.Participants
A total of 2154 participants recruited from 2009 to 2013 and randomized to HF versus TAU (67% male, mean age 40.8 ± 11.2, 25% ethno‐cultural minority). All were homeless and had a mental disorder at baseline; 35% reported symptoms consistent with SUD.Intervention
Housing paired with Intensive Case Management or Assertive Community Treatment.Measurements
Primary outcomes were days housed and community functioning. Secondary outcomes were general and health‐related quality of life and mental health symptoms. Predictors were SUD status crossed with intervention group (HF versus TAU).Findings
People with SUD in both the HF and TAU groups spent less time in stable housing, but the effect of HF did not vary by SUD status [odds ratio (OR) = 1.17, 95% confidence interval (CI) = ?0.77, 1.76]. Similarly, there was no difference between those with and without SUD in the effect of HF (over TAU) on community functioning (b = 0.75, 95% CI = ?0.36, 1.87), quality of life (b = ?1.27, 95% CI = ?4.17, 1.63), health‐related quality of life (b = ?0.01, 95% CI = ?0.03, 0.02) or mental health symptoms (b = 0.43, 95% CI = ?0.99, 1.86).Conclusions
Housing First programs in Canada are equally effective in people with and without comorbid substance use disorder (SUD). Overall, the intervention appears to be able to engage people with SUD and is reasonably successful at housing them, without housing being contingent upon abstinence or treatment. 相似文献14.
Raptis D Mantzoros I Pramateftakis MG Despoudi K Zaraboukas T Koliakos G Kanellos I Lazarides Ch 《International journal of colorectal disease》2012,27(3):299-308
Aim
The aim of this experimental study is to investigate the effects of tacrolimus on colonic anastomotic healing after subcutaneous administration. 相似文献15.
Cannabidiol reverses attentional bias to cigarette cues in a human experimental model of tobacco withdrawal
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Chandni Hindocha Tom P. Freeman Meryem Grabski Jack B. Stroud Holly Crudgington Alan C. Davies Ravi K. Das William Lawn Celia J. A. Morgan H. Valerie Curran 《Addiction (Abingdon, England)》2018,113(9):1696-1705
Background and Aims
Cannabidiol (CBD), a non‐intoxicating cannabinoid found in cannabis, may be a promising novel smoking cessation treatment due to its anxiolytic properties, minimal side effects and research showing that it may modify drug cue salience. We used an experimental medicine approach with dependent cigarette smokers to investigate if (1) overnight nicotine abstinence, compared with satiety, will produce greater attentional bias (AB), higher pleasantness ratings of cigarette‐related stimuli and increased craving and withdrawal; and (2) CBD in comparison to placebo, would attenuate AB, pleasantness of cigarette‐related stimuli, craving and withdrawal and not produce any side effects.Design
Randomized, double‐blind cross‐over study with a fixed satiated session followed by two overnight abstinent sessions.Setting
UK laboratory.Participants
Thirty non‐treatment‐seeking, dependent cigarette smokers recruited from the community.Intervention and comparator
800 mg oral CBD, or matched placebo (PBO) in a counterbalanced orderMeasurements
AB to pictorial tobacco cues was recorded using a visual probe task and an explicit rating task. Withdrawal, craving, side effects, heart rate and blood pressure were assessed repeatedly.Findings
When participants received PBO, tobacco abstinence increased AB (P = 0.001, d = 0.789) compared with satiety. However, CBD reversed this effect, such that automatic AB was directed away from cigarette cues (P = 0.007, d = 0.704) and no longer differed from satiety (P = 0.82). Compared with PBO, CBD also reduced explicit pleasantness of cigarette images (P = 0.011; d = 0.514). Craving (Bayes factor = 7.08) and withdrawal (Bayes factor = 6.95) were unaffected by CBD, but greater in abstinence compared with satiety. Systolic blood pressure decreased under CBD during abstinence.Conclusions
A single 800‐mg oral dose of cannabidiol reduced the salience and pleasantness of cigarette cues, compared with placebo, after overnight cigarette abstinence in dependent smokers. Cannabidiol did not influence tobacco craving or withdrawal or any subjectively rated side effects. 相似文献16.
Mercalli A Lampasona V Klingel K Albarello L Lombardoni C Ekström J Sordi V Bolla A Mariani A Bzhalava D Dillner J Roivainen M Bosi E Piemonti L 《Diabetologia》2012,55(9):2479-2488
Aims/hypothesis
The purpose of this study was to investigate whether the gut mucosa is a reservoir for enterovirus persistence in patients with type 1 diabetes. 相似文献17.
Mei PJ Bai J Liu H Li C Wu YP Yu ZQ Zheng JN 《Journal of cancer research and clinical oncology》2011,137(12):1823-1830
Purpose
The aim of this study is to investigate whether the expression of RUNX3 is related to the development of glioma, and the role of RUNX3 in glioma cells growth, invasion and migration. 相似文献18.
Paul J. Mills Loki Natarajan Roland von Känel Sonia Ancoli-Israel Joel E. Dimsdale 《Sleep & breathing》2009,13(4):415-420
Objective
The objective of this study is to examine the diurnal variability of C-reactive protein (CRP) in obstructive sleep apnea (OSA). 相似文献19.
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