自体表皮细胞移植治疗白癜风影响皮片成活率的因素探讨

目的　探讨自体表皮细胞移植治疗白癜风影响皮片成活率因素。方法　选择腹部皮肤为供皮区 ,予PFG Ⅰ表皮细胞分离机进行负压与温度双重分离 ,使其形成水疱 ,将供皮区的疱壁剪下备用。受皮区局麻后 ,子皮肤磨削机磨去白斑表皮 ,直至局部出现点状出血为止。将供皮区剪下的疱壁覆盖于受皮区 ,供应区及受皮区分别加压包扎 ,定期观察皮片成活情况。结果　 3 84例患者进行自体表皮细胞移植术后 ,有 3 67例皮片成活 ,成活率占治疗总数 91 .3 6%;未成活 1 7例 ( 2 4块 )占治疗总数 4.42 %。皮片未成活原因 ( 1 )创面感染化脓 3例 ( 5块 )占治疗总数 0 .78%。 ( 2 )创面术后浸水 6例( 7块 )占治疗总数 1 .5 6%。 ( 3 )正常表皮贴反了 2例 ( 2块 )占治疗总数 0 .5 2 %。 ( 4 )受皮创面太浅 2例( 3块 )占治疗总数 0 .5 2 %。 ( 5 )移植术后皮片过早脱落 4例 ( 7块 )占治疗总数 1 .0 4%。结论　自体表皮细胞移植治疗白癜风疗效确切 ,皮片成活率高 ;明确了影响皮片成活率的因素及制定相应的预防措施 ,能够进一步提高皮片的成活率。     

自体表皮细胞移植加斯奇康联合治疗白癜风

1998 - 0 2～ 2 0 0 1- 10 ,我们在应用负压吸引发泡自体表皮细胞移植法基础上加用免疫调节剂治疗白癜风 79例 ,并与单独采用自体表皮细胞移植病例对照 ,取得了明显的疗效。现报告如下。1　资料和方法1.1　病例 :共 2 2 5例 ,均为具有典型临床表现且对其他方法疗效不佳、处于稳定期 (指近 6个月无新皮损出现 )的白癜风患者。随机分为两组 :治疗组 79例 ,男 4 5例 ,女 34例 ,年龄12～ 5 5岁 ,病程 7月～ 19年 ,其中局限型 6 7例 ,泛发型 12例。对照组 136例 ,年龄 9～ 6 0岁 ,病程 7月～ 37年 ,其中局限型 12 9例 ,泛发型 7例 ;男 77例 ,女 5…     

负压吸疱自体表皮移植治疗白癜风

我科于１９９６年４～１２月，采用负压吸疱自体表皮移植治疗白殿风１２例，取得了满意效果，现报告如下：１　临床资料：白癜风患者１２例，均为男性；年龄１８～３２岁，平均２２．３３岁；病程３月～１２年，平均８．４年；局限型３例，散发型６例，肢端型３例，其中１例合并原发性甲状腺机能亢进症；以上患者大多数曾用多种方法治疗无效。２　治疗方法：器械采用上海医科大学物理教研室研制的表皮分离机。治疗前部分病人简单备皮，治疗时白斑区和供皮区各吸一个０．５～１．０ｃｍ大小水疱，工作负压４０～７０ｋＰａ，时间１．５～４ｈ…     

负压吸疱法及薄层削片法白癜风自体表皮移植疗效观察

目的探讨负压吸疱法及薄层削片法自体表皮移植治疗白癜风的疗效观察。方法将86例患者按取皮方法不同分为薄层削片组42例及负压吸疱组44例,观察自体表皮移植后的疗效。结果术后8周,薄层削片法自体表皮移植的总有效率明显高于负压吸疱法(P<0.01)。结论薄层削片法自体表皮移植治疗白癜风较负压吸疱法简便有效。     

自体表皮细胞移植术治疗白癜风384例

自体表皮细胞移植术治疗白癜风效果好、操作简便、见效快、不良反应少。 1995～ 2 0 0 1年 ,我院门诊采用此法治疗白癜风 384例 ,总治愈率 91 4 % ,发生创面感染 3例 (0 78% ) ,贴反表皮 2例(0 5 2 % ) ,创面浸湿 6例 (1 5 1% ) ,受皮创面太浅 2例 (0 5 2 % ) ,手术植表皮脱落 4例 (1 0 4 % )。总疗效良好。1　临床资料1 1　一般情况　 384例中 ,男 2 39例 ,女 14 5例 ;年龄 7～ 15岁 ,平均 17 2岁。病程 5个月～ 2 1年 ,平均 3 96年。寻常型 10 8例 ,节段型 2 76例。皮损发生在面颈部最多 ,四肢躯干次之 ,合并银屑病 2例。1 2　诊断标准…     

自体表皮细胞移植治疗白癜风疗效观察

目的 评价自体表皮细胞移植治疗白癜风的疗效。方法 对136例白癜风患者用自体表皮细胞移植方法治疗后随访半年结果分析。结果 痊愈 12例(8.8％),显效104例(76.5％),有效18例(13.2％),无效2例(1.5％)。总有效率90％以上。结论 自体表皮细胞移植治疗白癜风操作简单,疗效显著。     

超脉冲CO_2激光在白癜风表皮移植中的应用

正目的:观察超脉冲CO_2激光磨削方法在表皮移植术治疗白癜风中的应用效果。方法:采用随机对照实验研究方法,将57例筛选合格的稳定期白癜风患者随机分配到两组,采用超脉冲CO_2激光磨削白斑区31例(A组),滚轮磨削白斑区26例(B组),然后进行负压吸疱自体表皮移植术,观察表皮移植后的疗效及手术的便利性和时间等。     

应用ReCell技术移植治疗稳定期白癜风的临床疗效观察

 目的 观察ReCell技术移植治疗稳定期白癜风的临床疗效。方法 选择2015-07至2017-07稳定期白癜风患者21例,黑素细胞来源采用正常皮肤发疱的方法,应用ReCell技术将疱壁制成含有黑素细胞的表皮细胞混悬液,将表皮细胞混悬液种植于白斑皮损创面,移植后观察临床治疗效果。结果 21例白癜风患者中的33块白癜风皮损进行了移植治疗,移植后皮损均出现程度不等的复色,移植后6个月的3、4级复色率达87.09%,移植后未见不良反应。结论 应用ReCell技术移植治疗稳定期白癜风,具有移植区复色效果好、供皮区不留瘢痕的优点,并且临床上安全性可靠,操作相对简单,不需要专门的实验室,值得临床推广应用。     

表皮移植术治疗白癜风68例

笔者应用表皮细胞分离机分离自体表皮，然后行皮肤移植治疗白癜风68例，收到较满意效果，现报告如下。1临床资料1．1一般情况本组男24例，女44例，年龄11～65岁，病程2个月～15年。病灶分布多在面、颈、四肢。1．2治疗方法（1）选准正常皮肤取皮位置，确定治疗病灶区后，行碘酒、乙醇常规消毒，覆盖洞巾，将表皮细胞分离机的负压定在40～60kPa，温度定在35～45℃．分别将取皮器置放在预定皮肤上，开机60～80min，见取皮器孔内水疤形成即表明表皮与真皮已分离。停机取下取皮器，清除病灶上表皮，而后将正常皮肤的痕壁沿边缘剪下移植在病灶创…     

自体表皮细胞移植治疗白癜风疗效观察

目的：评价自体表皮细胞移植治疗白癜风的疗效。方法：对136例白癜风患用自体表皮细胞移植方法治疗后随访半年结果分析。结果：痊愈12例（8．8％）,显效104例（76．5％）,有效18例（13．2％）,无效2例（1．5％）。总有效率90％以上,结论：自体表皮细胞移植治疗白癜风操作,疗效显。     

Optimization of the system of medical service of students of Cadet Schools of the Ministry of Defense of the Russian Federation

One of the factors of the successful military career guidance Cadet schools students is preserving and promoting their health. Medical support of children and adolescents aged 10-17 years should include the full range of medical and preventive measures defined for this group. The state of providing outpatient care for pupils at the Cadet School in St. Petersburg was studied. These results show that full medical care in accordance with the standards can be based only on children's health clinics. It is important that the organization of medical support pupils cadet schools should be cooperate with civilian health care.     

带状疱疹83例误诊原因分析

带状疱疹是由水痘—带状疱疾病毒引起的皮肤科常见疾病。其主要的病理损害,一是受累神经的严重炎症性浸润,继而导致受侵犯神经节内神经细胞变性、坏死;二是皮肤的水泡。迅速抑制神经节和相应的感觉神经纤维的充血、水肿和坏死,防止粘连形成,达到迅速镇痛、改善皮损,缩短病程及防止后遗症的发生是治疗的关键。因而,尽早明确诊断,     

Estimation of accumulated dose of radiation by method of ESR-spectrometry of dental enamel of mammals

ESR-spectrometry was used to investigate radiation-induced paramagnetic centers in enamel of mammals: carnivores (polar bear and fox), ungulates (reindeer, European bison, moose), and man. Values at half the microwave power saturation of the radiation signal, P_1/2, evaluated at room temperature, was found to range from 16 to 26 mW for animals and man. A new approach to discrimination of the radiation induced signal from the total ESR spectrum of reindeer enamel is proposed. ‘Dose-response’ dependencies of enamel of different species mammals were measured within the dose range from 0.48 up to 10.08 Gy. Estimations of ‘radiosensitivity’ enamel of carnivores and ungulates showed good agreement with radiosensitivity enamel of man by ESR method.     

Analysis of the results of the international comparison of activity measurements of a solution of Fe

The results of an international comparison of activity measurements of a solution of ⁵⁵Fe organized by the BIPM in 2005 are reported and analysed. This exercise, which follows the procedures of the CIPM mutual recognition arrangement to update older comparisons, is a renewal of the comparison organized by the BIPM that took place in 1978. A EUROMET comparison was organized in 1996 specifically to compare activity measurements of a ⁵⁵Fe solution by means of liquid-scintillation techniques. Results of these three comparisons are presented and discussed in this paper.

The radionuclide solution was provided by the NPL, which also distributed the samples to the participants. The activity of the ampoules was measured by 16 laboratories using 12 methods producing 25 results. Some general considerations on uncertainty assessments pertaining to the different techniques used are drawn. The outcome of four different estimators is compared from which the presence of at least one outlier can be confirmed. Further measurements should be made to try to reduce the discrepancy between the results. To date the outcome of the present comparison does not show an improvement to that of the 1996 comparison.     

Evaluation of the results of various technics of non-surgical therapy of varicocele

A new method of non-surgical treatment of varicocele syndrome is described: it consists in sclerotherapy of spermatic vein by trans-femoral percutaneous catheterization with balloon-catheters. In 8 cases venous thrombosis has been induced by direct electric clotting. The techniques and a 6 months follow-up are discussed. It is pointed out that this procedure should be considered as the method of choice for tubular lesions and sub-fertility prophylaxis in young people and in childhood.     

延迟性脾破裂误漏诊原因分析

目的探讨延迟性脾破裂误漏诊原因和预防措施.方法回顾性分析总结12例延迟性脾破裂中的诊断和误漏诊的经验与教训.结果本组延迟性脾破裂的误漏诊5例(41.66%).对多发伤与脾破裂并存可能认识不足,外伤史轻微或伤员隐瞒外伤史,缺乏腹痛-缓解-突然再腹痛的典型病史,缺乏“对冲性脾破裂”力学分析和整体化诊断思路等为其误漏诊的主要原因.结论详细的外伤史和全面系统检查,重视腹以外多发伤掩盖腹内脏器伤及延迟性脾破裂可能.确立外伤-腹内脏器伤-脾破裂整体化诊断思路.不间断地辅以B超检查脾形态学变化和腹内有无积液,腹腔穿刺确定有无血腹、X线胸腹部检查观察左侧胸肋角和膈肌运动情况、必要时CT检查以尽早发现脾包膜下血肿,降低延迟性脾破裂误漏诊率.