屏山县彝族人血型分布特点

ABO血型在人群中的分布,不同的民族各有其特点。人类红细胞ABO血型的群体调查,不仅为人类群体遗传学、人类学和医学遗传学提供基本资料,而且有助于研究各民族的遗传组成和人群血缘关系,并进一步探讨民族的起源、融合和迁移。屏山县毗邻大凉山,与四川省凉山彝族自治州中彝族同脉     

吉林省延边地区朝、汉族人群ABO、Rh血型分布调查

当今人类红细胞血型广泛地应用于医学遗传学、人类学、法医学、免疫学及临床医学各个领域。我国是一个多民族国家，每个民族的细胞抗原分布频率存在着明显的差异，调查各民族红细胞ABO、Rh血型分布对了解各民族的血型分布，对了解人类种族间差异，亲子鉴定和个体识别均具有重要意义。     

云南傣族、彝族和上海汉族人群中Miltenberger复合物频率调查

云南傣族、彝族和上海汉族人群中Ｍｉｌｔｅｎｂｅｒｇｅｒ复合物频率调查２０００２５上海第二医科大学上海市免疫学研究所范丽安许玲娣杨珏琴姚芳娟对我国各民族间的分化程度、祖缘关系及遗传变异的分布进行研究和探讨是遗传学研究的一个重要内容，红细胞血型作为人类遗...     

恶性淋巴瘤误诊l例

ABO血型分布与民族、地区有关 ,是研究人类遗传学的一种手段 ,我国幅员广阔 ,民族繁荣 ,血型分布差别甚大 ,了解该地区人群 ABO血型分布对本民族起源、遗传、融合以及对输血的研究具有一定意义。笔者对 976 82名无偿献血者的 ABO血型抗原分布及基因频率分布进行调查统计分析 ,结果报告如下。1　对象和方法1.1　对象　郑州地区无偿献血者 976 82名。1.2　试剂与仪器　抗 - A、抗 - B单克隆抗血清 (购自长春生物制品研究所 ) ;自制试剂红细胞 (A型和 B型红细胞分别取自 3人份的新鲜 ACD抗凝血 ,经过混合洗涤后配制成 5 %的试剂红细胞 )…     

郑州地区无偿献血人群ABO血型分布调查

ABO血型分布与民族、地区有关,是研究人类遗传学的一种手段,我国幅员广阔,民族繁荣,血型分布差别甚大,了解该地区人群ABO血型分布对本民族起源、遗传、融合以及对输血的研究具有一定意义.笔者对97682名无偿献血者的ABO血型抗原分布及基因频率分布进行调查统计分析,结果报告如下.     

海南地区汉族人群红细胞血型分布

红细胞血型是最早发现的人类血型，为人类一种遗传标记，对人类学、遗传学、输血、配型、器官移植和新生儿免疫性疾病具有重要意义。现将近年来海南地区汉族人群红细胞血型的分布情况报告如下。     

常武地区人群ABO及Rh血型分布调查

血型分布与民族、地区有关，血型调查是研究人类种族遗传的手段之一。笔者对常武地区献血人群进行ABO及Rh血型普查，现将调查结果报告如下。     

芜湖地区汉族献血者ABO、Rh、MN和P血型的调查

人类红细胞血型是遗传多态性的标志之一,对人类学、遗传学、临床输血、配型、器官移植和新生儿免疫性疾病研究都具有重要意义。由于血型抗原在不同种族、不同地区人群中的分布存在差异,因此掌握本地区人群中血型抗原的分布规律,可有效指导安全输血工作。现将芜湖地区汉族人群AB0、Rh、MN和P血型的分布情况报告如下。     

云南省峨山县彝族人红细胞EsD和PGM_1分型调查及其频率研究

<正> 酯酶D(EsD)和磷酸葡萄糖变位酶-1(PGM_1)都是人类红细胞中血型物质外的具有基因标志的重要酶类,它们的基因分别定位在第13号和第1号常染色体上.调查这两种同工酶的表型在不同人群中的分布,对于人类群体遗传学、法医学以及临床医学等方面的研究都具有重要价值.为了解EsD和PGM_1在彝族人群中的分布,我们采用淀粉/琼脂糖混合凝胶同步电泳法,抽样调查了云南省峨山彝族自治县172名无关的健康彝族人红细胞EsD和PGM_1的表型分     

羌族ABO、Rh、MN、P血型系统调查

<正> 红细胞血型作为人类的一种遗传标记,对于人类学和遗传学研究的重要意义已被确认。近年来有关我国部分少数民族的红细胞血型分布已有过报道,但对聚居于四川西北地区的羌族人红细胞血型调查尚未见报道。1989年我们在四川省阿坝藏族、羌族自治州赤不苏乡,对196名羌族人进行 ABO、Rh、MN、P 血型分布的调查,现将结果报道如下。     

Measurement of L-carnitine and acylcarnitines in body fluids and tissues in children and in adults

We have developed a reliable and validated radio-enzymatic method for the assay of L-carnitine and acylcarnitines, using a modification of existing methods. The sensitivity of the assay is 10 mumol/l using 10 microliters of plasma or urine. It is also suitable for measurements of carnitine in a 10 mg sample of liver or muscle obtained by percutaneous biopsy. The use of N-ethylmaleimide in the reaction mixture together with an excess of [1-14C]acetyl CoA ensures that the reaction proceeds to completion and a linear response is obtained. Using this method control ranges have been established for plasma and urine carnitine concentrations in healthy children and adults, and for the carnitine content of liver and muscle in adults. No significant difference was found between fasting and post-prandial plasma carnitine levels. An age-related increase was found in urinary total carnitine and acylcarnitine concentration throughout childhood. These data provide a reliable basis for studies of patients with abnormal carnitine and acylcarnitine metabolism, distribution and excretion.     

Rosamicin in Urethral and Vaginal Secretions and Tissues in Dogs and Rats

In animal studies we investigated the distribution of rosamicin in plasma and urethral and vaginal tissues in rats as well as in urethral and vaginal secretions in dogs. We found concentration ratios between urethral secretion and plasma of 1.9 and between vaginal secretion and plasma of 2.4. The rosamicin concentrations in urethral and vaginal tissue significantly exceeded the levels of all other tissues investigated. Because rosamicin could be valuable for the treatment of bacterial urethritis and the colonization of the vaginal introitus with fecal bacteria in women, it should be investigated clinically in this respect.     

Similarities and differences in clients treated and in medications prescribed by APRNs and psychiatrists in a CMHC

This study is part of a larger study comparing prescribing practices of psychiatrists and advanced practice psychiatric nurses (APRNs) using the following three groups of patients: patients treated by psychiatrists, those treated by APRNs, and those treated by both APRNs and psychiatrists at different times in 1 year. Demographics for 5507 patients were examined. A subsample of APRNs and psychiatrists prescribed similar total numbers of medications. Psychiatrists prescribed more types of antidepressant medications other than the SSRI antidepressants, and they prescribed more than twice the number of benzodiazepines. APRNs prescribed more SSRIs and spent more time with clients during medication visits.     

Racial differences in oxidative stress and inflammation: in vitro and in vivo

African American race is an independent risk factor for enhanced oxidative stress and inflammation. We sought to examine whether oxidative-stress and inflammatory markers that are typically measured in humans also differ by race in cell culture. We compared levels between African American and Caucasian young adults and then separately in human umbilical vein endothelial cells (HUVECs) from both races. We found heightened oxidative stress and inflammation in the African Americans both in vitro and in vivo. African American HUVECs showed higher nitric oxide (NO) levels (10.8 ± 0.4 vs. 8.8 ± 0.7 μmol/L/mg, p = 0.03), Interleukin-6 (IL-6) levels (61.7 ± 4.2 vs. 23.9 ± 9.0 pg/mg, p = 0.02), and lower superoxide dismutase activity (15.6 ± 3.3 vs. 25.4 ± 2.8 U/mg, p = 0.04), and also higher protein expression (p < 0.05) of NADPH oxidase subunit p47phox, isoforms NOX2 and NOX4, endothelial nitric oxide synthase (NOS), inducible NOS, as well as IL-6. African American adults had higher plasma protein carbonyls (1.1 ± 0.1 vs. 0.8 ± 0.1 nmol/mg, p = 0.01) and antioxidant capacity (2.3 ± 0.2 vs. 1.1 ± 0.3 mM, p = 0.01). These preliminary translational data demonstrate a racial difference in HUVECs much like that in humans, but should be interpreted with caution given its preliminary nature. It is known that racial differences exist in how humans respond to development and progression of disease, therefore these data suggest that ethnicity of cell model may be important to consider with in vitro clinical research.     

Postural strategies and falls in elderly and in parkinsonism]

OBJECTIVE: To use a posture analysis to show the evolution of postural pattern connected with falls.MATERIAL AND METHOD: It is a prospective study on two groups of 16 persons of more than 60 years. A group concerns 16 small disability off drug parkinsonian patients, a group concerns 16 healthy witnesses. All the persons benefited from a posture recording by means of a force platform and were followed during 1 year. RESULTS: Data analysis underlines three groups of persons corresponding to three postural patterns, independently of the presence of Parkinson disease. A group (n = 18) did not contain fallers, the second (n = 10 ) contained 20% of fallers, the third (n = 4) contained 100% of fallers. Differences between the groups were identified on 16 posturographic parameters. DISCUSSION: A group has a good functional value and one does not record any fall. Its characteristics, which correspond to a category of persons who compensate well for the phenomena of ageing, are found in the literature. A group has an intermediate functional value and regrets 20% of fallers. Kinetic profile reveals a tendency to the stiffness of the posture. This group is going to operate rather ankle strategies. A group has an inferior functional value and regrets 100% of fallers. Kinetic profile seems disrupted and not to be able to adapt itself in a satisfactory way to the situation otherwise than by stereotypical reactions. This group is going to operate systematically much less stabilizing hip strategies. CONCLUSION: A close determinism between physiological neuromotor ageing and Parkinson disease does exist. We showed with a prospective follow-up, the arisen of fall and showed the evolution of postural patterns related to fall. It appears as well that evolution mainly follows three stages leading from a small risk of fall gait pattern to a major risk of fall gait pattern.