Prévention des hémorragies digestives hautes de stress en réanimation Révision de la conférence de consensus de 1988

Experts designated by the Société de réanimation de langue française had to audit the 1988 French consensus about upper gastrointestinal bleeding in critically ill patients. In the last decades the incidence of this nosocomial complication has dramatically decreased. A high-risk population has to be defined. H2 antagonists and sucralfate seemed to be more effective than antacids and prostaglandins. Proton pump inhibitors and enteral nutrition could be alternative prophylaxis. The cost-effectiveness ratio wasn't completely defined but implantation of clinical guidelines may reduce costs and limit such treatment for high-risk patients.     

Phytothérapie de la dépression

Editorial

Le changement     

Génétique de la migraine

The principal advances in understanding of the molecular genetics of migraine come from studies of familial hemiplegic migraine (FHM), a rare migraine variant with aura, which has autosomal dominant inheritance. Three genes have been identified, all of which code for ion transporters. In cellular models and in transgenic mice, mutations causing FHM result in neuronal hyperexcitability, thus facilitating the triggering of waves of cortical spreading depression, the phenomenon which underlies the migrainous aura. Large numbers of linkage analysis and association studies in the most common forms of migraine, whether with or without aura, have yielded inconclusive results. This is probably due to the clinical heterogeneity of migraine. New methods of phenotype analysis and of exploration of association over the whole genome now seem to offer the best chance of identifying the genes of migraine.     

Impact de l'échoendoscopie dans la prise en charge de l'adénocarcinome pancréatique

Acta Endoscopica - L'hôpital de jour était utilisé par des patients plus jeunes. On notait l'importance de la consultation auprès d'un gastro-entérologue qui...     

Réactualisation de la douzième conférence de consensus de la Société de réanimation de langue française (SRLF) : infections liées aux cathéters veineux centraux en réanimation

Concerning catheter-related infections, many studies have been conducted until the last consensus conference of the Société de réanimation de langue française (SRLF) in 1994. This text is the synthesis of the considerable amount of work performed by the experts of the society to review recent studies. The experts’ texts as well as extensive bibliography are available at http://www.srlf.org.