壮族大学生Heath-Carter法体型研究

目的：探讨壮族大学生的体型特征。方法：用Heath-Carter人体测量方法472名（男272，女200）19－21岁的壮族大学生进行了体型评定，结果：壮族大学生男，女的平均体型值为2．2－3．9－3．1和3．8－3．4－2．7，男女间SAD值为1．70，T为6．9，结论：壮族大学生男，女分别属偏外胚层的中胚层体型和偏中胚层的内胚层体型。壮族大学男，女性的体型有非常显著性差异（P＜0．01），与国内外资料相比，壮族大学生的内，中因子值偏低，外因子值相关不大。     

辽西地区农村汉族成人体型分析

目的 探讨辽西农村汉族成人的体型特征,为体质人类学补充必要的资料.方法 采用Heath-Carter人体测量法对辽西地区义县七里河乡506名（男247,女259）20～82岁间的汉族成人进行了体型评定.结果 辽西汉族农民成年男性的平均体型值为4.9-3.5-2.3,成年女性的平均体型值为6.0-3.1-1.9,两者均属偏中胚层的内胚层体型;经t检验,40～44岁年龄组男女体型有显著差异.通过与辽西地区城市汉族成人的比较,可以看出,辽西汉族农村男女的内因子值明显低于城市男女,中因子值和外因子值两者基本接近.结论 辽西汉族农民皮下脂肪较厚,骨骼、肌肉系统较发达,身体线性度中等.     

辽西地区城市汉族成人的Heath-Carter法体型研究

目的 探讨辽西地区城市汉族成人的体型特征,为体质人类学补充必要的资料。方法采用Heath-Carter人体测量法对辽西地区锦州市区496名（男243,女253）20～81岁间的汉族成人进行了体型评定。结果锦州市区汉族成年男性平均体型值为5．7-3．3-2．1,成年女性的平均体型值为7．0-3．0-1．7,两者均属偏中胚层的内胚层体型;经t检验,20～24岁、25～29岁和55岁以上年龄组男女体型有显著差异;随着年龄的增长,辽西城市汉族成年男女内、中因子值上升,外因子值下降,通过与我国六个少数民族成人体型的比较,可以看出辽西城市汉族成人的体型与其他民族体型差异较大。结论辽西地区城市成年男女皮下脂肪较厚,骨骼、肌肉系统一般发达,身体线性度较低,特别是较高的体脂率应引起人们的重视。     

沧州社区汉族成人Heath-Carter法体型研究

目的:探讨沧州社区汉族成人的体型特征。方法:采用Heath-Carter人体测量法对沧州社区汉族成人20-91岁总计867人(男516人,女351人)进行了体型评定。结果:沧州社区汉族成人男性的平均体型值为4.70-5.55-2.41,属于偏内胚层的中胚层型,各年龄组中以偏内胚层型的中胚层型为主。沧州社区汉族成人男性20-岁,30-岁和40-岁的内因子值逐渐上升,而50-岁组以后的内因子值下降;中因子值20-,30-组逐渐上升,40-岁以后下降;外因子值20-,30-和40-岁组变化不大,50-组外因子值升高。社区女性平均体型值为6.32-5.43-1.63,属偏中胚层的内胚层型,以偏中胚层型的内胚层型、内胚层-中胚层均衡型及偏外胚层的内胚层型为主。女性20-,30-和40-岁组的内因子值逐渐上升,50-岁以后下降;女性中因子值和外因子值各年龄组变化不明显。结论:沧州社区汉族成人男女间体型比较有显著性差异。随着年龄的增长,男、女性中因子值上升,外因子值下降。与国内其他族群比较,沧州社区汉族成人体型,山东城市汉族体型、山西城市汉族、内蒙古汉族、大连市汉族比较接近,具有我国北方族群体型的共同特征。     

云南汉族成人的Heath-Carter法体型研究

目的了解云南汉族成人的体型。方法应用Heath—Carter人体测量法对1090名（男492,女598名）年龄在20-59岁间的云南省昆明和玉溪两市的城乡汉族（简称云南汉族）进行体型评定。结果①云南汉族男性的平均体型值为3．8—4．4-2．6（城3．9—4．3-2．6,乡3．6—4．5-2．6）,属偏内胚层型的中胚层型,各年龄组中以偏内胚层型的中胚层型、偏中胚层型的内胚层型及内胚层一中胚层均衡型为主。②女性的平均体型值为5．3-3．9-2．0（城5．3-3．8-2．0,乡5．3-4．0-2．0）,属偏中胚层型的内胚层型;以偏中胚层型的内胚层型、内胚层-中胚层均衡型及偏外胚层型的内胚层型为主。③随着年龄的增长,男女性（20-54岁）内、中因子值上升,外因子值下降。结论云南汉族成年人体型男女两性间存在性别差异,但无城乡差异。     

瑶族体型的Heath—Carter人体测量法研究

的　探讨瑶族成人体型的特点与规律。方法　应用Heath -Carter人体测量法 ,对广西田林县利周乡 2 18例(男 116 ,女 10 2 ) 2 0～ 45岁盘古瑶族成人体型进行活体测量。结果　瑶族平均体型男性为均衡的中胚层体型 ( 1.8-4 .9-2 .2 ) ,女性为偏内胚层的中胚层体型 ( 3 .1-4 .3 -1.9) ;瑶族男性 2 0～ 40岁间各年龄组 ,内因子值和中因子值变化不大 ,外因子值略有减少 ,内、中因子值的最小值及外因子值的最大值均在 40～ 45岁组 ;女性 2 0～ 45岁间各年龄组 ,随着年龄增加 ,外因子值明显增加 ,中、内因子值略有减少 ;瑶族男女间体型各年龄组比较差异均有显著性或高度显著性 ,P<0 .0 5或P <0 .0 1。结论　瑶族与其他群体体型比较 ,体脂少 ,骨骼肌肉较发达 ,身体线性度适中。     

广西百色市某中学12～16岁壮族青少年跟骨骨密度与身体成分的相关性研究

目的探究广西百色市某中学12~16岁壮族青少年年龄、性别、身高、体重、肌肉量、脂肪量与跟骨骨密度宽频超声衰减值(BUA)的相关性,为增强壮族青少年的骨骼成长提供一定的理论依据。方法随机抽取780例(男性280例,女性500例)广西百色市某中学壮族学生作为研究对象,将受试者分为12~12.99岁、13~13.99岁、14~14.99岁、15~15.99岁、16~16.99岁五个年龄组,进行跟骨骨密度和身体成分的测试,并计算和比较骨密度测试结果及其与身体成分的相关性。结果随着年龄的增长,广西百色市某中学12~16岁壮族男、女青少年的身高、体重、肌肉量有逐渐增高趋势。对男女青少年体重、身高、BMI、肌肉量和脂肪量的成组单因素方差分析结果表明,除男女性青少年脂肪量和女性BMI组内比较差异无统计学意义外,其余各因子组内比较差异均有统计学意义(P均<0.001)。BUA值男女组内比较差异均有统计学意义(F=3.55,P=0.07;F=5.77,P<0.001)。男女性年龄、身高、体重及男性肌肉量与BUA呈正相关。男女性青少年脂肪量、女性青少年肌肉量与BUA值无关。结论广西百色市某中学壮族男女青少年年龄间隔1年左右同一性别在体重、身高、肌肉量、BUA值等变化并不明显,与脂肪量无关,BUA与T值有相关性。     

广西东部壮族成人皮褶厚度及其年龄变化特征

目的：探索广西东部（桂东）壮族成人体脂发育水平及年龄变化特征。方法：测量532例壮族成人6项皮脂厚度。结果：①皮褶厚度值男性为4～12mm;女性7～15mm。皮下脂肪男性以躯干背部最厚,面部、腹部居中;女性以臂后上部和面颊部最厚,腹部和背部居中,男女均为下肢脂肪最薄。②皮下脂肪男性34岁以前增厚明显,以后稍有下降并随年龄增加其在一定水平保持较为平稳的状态;女性皮下脂肪50岁以前保持在较高水平,以后则明显下降。结论：桂东壮族成人皮下脂肪发育以上肢和面部较发达,腹部居中,而下肢最薄为特征。     

我国北方五个少数民族成人的体型

用Heath-Carter法对我国北方5个少数民族（蒙古族、达斡尔族、鄂温克族、鄂伦春族、回族）成人的体型进行了研究。5个民族的平均体型均为偏中胚层的内胚层体型;男性蒙古族为内胚层－中胚层均衡体型,回族为均衡的中胚层体型,达斡尔族、鄂温克族和鄂伦春族均为偏内胚层的中胚层体型。20－40岁期间,随着年龄的增长,各年龄组的内、中因子值有所上升,而外因子值有下降的趋势。5个少数民族体型的性别差异均甚显著。所得结果与国外的资料进行了比较。     

广西汉族成人的体型研究

目的:探讨我国广西汉族成人的体型特征.方法:采用Heath-Carter人体测量法对广西汉族成年人20～65岁共979人[其中男性493人(城市241人、乡村252人),女性486人(城市245人、乡村241人)],进行体型评定.结果:①广西汉族成人男女的平均体型值分别为4.9-4.7-2.4和5.9-3.7-2.3;汉族成人男性属内胚层-中胚层均衡体型,女性属偏中胚层型的内胚层体型;②随着年龄的增长,城市男性20岁～到35岁～组内因子值上升,40岁～到45岁～增长最快,50岁～后缓慢减少,中因子值变化不大,外因子值下降;乡村男性内、中、外因子值变化不大;③随着年龄的增长,城市女性内、中因子值上升,外因子值下降;乡村女性内、中、外因子值变化不大;④广西汉族成人体型城、乡和性别间均存在明显差别.结论:广西汉族男性平均体型与国内的山东汉族和蒙古族较为接近,与国外资料的美国东北和中西部人群接近;女性平均体型与国内的蒙古族和鄂伦春族较为接近,与国外资料的印度锡克族、旁遮族及墨西哥人较接近.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.