Influence of nursing intervention on quality of Ilife in patients with systemic lupus erythematosus

Objective To observe the influence of nursing intervention on quality of life in patients with systemic lupus erythematosus（SLE） . Methods Eighty three patients and 83 healthy controls were enrolled in this study. The medical outcomes study 36--item short--front health survey （MOS SF--36） Was used for measuring the quality of life. The SF--36 Scores of the two groups were investigated and analyzed before and after the nursing intervention. Results At the baseline, the physical function, role physical bodily pain, general health and role emotional scores in the SLE patients were significantly different from those of health control （P 〈 0. 01）. Items above mentioned in SLE patients got significantly better after one-- years nursing intervention （P〈 0.05）. Conclusions The quality of life in SLE patients is lower than healthy group. Nursing intervention can significantly improve the quality of life in SIrE patients.     

Body mass index and COVID-19 outcomes:A retrospective cross-sectional study at a tertiary care center in India

Objective:To determine the association between body weight and COVID-19 outcomes.Methods:This is a retrospective cohort study of COVID-19 patients admitted in a dedicated COVID-19 hospital,a tertiary health care center,between May and June 2021.Demographic data and baseline variables,including age,sex,body mass index(BMI),and comorbidities were collected.Outcomes(death or mechanical ventilation)of the patients with different BMI,age,comorbidities,and qSOFA scores were compared.Besides,the risk factors for death or mechanical ventilation were determined.Results:The mean age of the subjects was(51.8±14.7)years old,and 233(74.2%)were male.There were 103(32.8%)patients with normal weight,143(45.5%)patients were overweight,and 68(21.7%)patients were obese.In-hospital deaths and need of mechanical ventilations were significantly higher in the obese and the overweight group compared to the normal weight group,in age group≥65 years compared to<65 years,in patients with≥1 comorbidities compared to patients without comorbidities,in patients with qSOFA scores≥2 compared to patients with qSOFA scores<2.There was a significantly increased risk of death(RR:4.1,95%CI 1.0-17.4,P=0.04)and significantly increased need of mechanical ventilation(RR:5.2,95%CI 1.8-15.2,P=0.002)in the obese patients compared with those with normal weight after controlling other covariates.Conclusion:Obesity is one of the significant risk factors for adverse outcomes in COVID-19 patients and should be considered during management.     

Removal of biofilm is essential for long-term ventilation tube retention

BACKGROUND Although long-term retention of a ventilation tube is required in many ear diseases,spontaneous removal of conventional ventilation tube is observed in patients within 3 to 12 mo.To address this issue,we aimed to determine a new method for long-term retention of the ventilation tube.AIM To explore the value of removing the biofilm for long-term retention of tympanostomy ventilation tubes.METHODS A case-control study design was used to evaluate the safety and effectiveness of long-term tube retention by directly removing the biofilm(via surgical exfoliation)in patients who underwent myringotomy with ventilation tube placement.The patients were randomly divided into two groups:Control group and treatment group.Patients in the treatment group underwent regular biofilm exfoliation surgery in the clinic,whereas those in the control group did not have their biofilm removed.Only conventional ventilation tubes were placed in this study.Outcome measures were tube position and patency.Tube retention time and any complications were documented.RESULTS Eight patients with biofilm removal and eight patients without biofilm removal as a control group were enrolled in the study.The tympanostomy tube retention time was significantly longer in the treatment group(43.5±26.4 mo)than in the control group(9.5±6.9 mo)(P=0.003).More tympanostomy tubes were found to be patent and in correct position in the treatment group during the follow-up intervals than in the control group(P=0.01).CONCLUSION Despite the use of short-term ventilation tubes,direct biofilm removal can be a well-tolerated and effective treatment for long-term tube retention of tympanostomy ventilation tubes in patients who underwent myringotomy.     

社会支持对肝硬化患者生活质量的影响研究

Objective To discuss the effect of social support to the quality of life of the patients with hepatocirrhosis. Methods 98 hepatocirrhosis patients in our hospital were divided into observation and control groups. Both the groups were accepted routine therapy and nursing while striving for social support for the patients of observation group, then having a whole evaluation to the status of patients, in the study early interference and health education were important. SSRE (Social Support Rating Scale) and SF - 36QOL made by America medi-cine graduate school to research and survey the two patients. Results The whole mark of social support (46.33 ±3.78) and the whole health of QOL (78.86±11.31 ) and every dimensionality of observation group were all bet-ter than those of control group (P<0.01) . Conclusions The social support can infect directly the QOL of pa-tients with hepatocirrhosis, all the doctors and nurses should recognition the system of social support, in order to improve the QOL of the patients.     

社会支持对肝硬化患者生活质量的影响研究

Objective To discuss the effect of social support to the quality of life of the patients with hepatocirrhosis. Methods 98 hepatocirrhosis patients in our hospital were divided into observation and control groups. Both the groups were accepted routine therapy and nursing while striving for social support for the patients of observation group, then having a whole evaluation to the status of patients, in the study early interference and health education were important. SSRE (Social Support Rating Scale) and SF - 36QOL made by America medi-cine graduate school to research and survey the two patients. Results The whole mark of social support (46.33 ±3.78) and the whole health of QOL (78.86±11.31 ) and every dimensionality of observation group were all bet-ter than those of control group (P<0.01) . Conclusions The social support can infect directly the QOL of pa-tients with hepatocirrhosis, all the doctors and nurses should recognition the system of social support, in order to improve the QOL of the patients.     

社会支持对肝硬化患者生活质量的影响研究

Objective To discuss the effect of social support to the quality of life of the patients with hepatocirrhosis. Methods 98 hepatocirrhosis patients in our hospital were divided into observation and control groups. Both the groups were accepted routine therapy and nursing while striving for social support for the patients of observation group, then having a whole evaluation to the status of patients, in the study early interference and health education were important. SSRE (Social Support Rating Scale) and SF - 36QOL made by America medi-cine graduate school to research and survey the two patients. Results The whole mark of social support (46.33 ±3.78) and the whole health of QOL (78.86±11.31 ) and every dimensionality of observation group were all bet-ter than those of control group (P<0.01) . Conclusions The social support can infect directly the QOL of pa-tients with hepatocirrhosis, all the doctors and nurses should recognition the system of social support, in order to improve the QOL of the patients.     

社会支持对肝硬化患者生活质量的影响研究

Objective To discuss the effect of social support to the quality of life of the patients with hepatocirrhosis. Methods 98 hepatocirrhosis patients in our hospital were divided into observation and control groups. Both the groups were accepted routine therapy and nursing while striving for social support for the patients of observation group, then having a whole evaluation to the status of patients, in the study early interference and health education were important. SSRE (Social Support Rating Scale) and SF - 36QOL made by America medi-cine graduate school to research and survey the two patients. Results The whole mark of social support (46.33 ±3.78) and the whole health of QOL (78.86±11.31 ) and every dimensionality of observation group were all bet-ter than those of control group (P<0.01) . Conclusions The social support can infect directly the QOL of pa-tients with hepatocirrhosis, all the doctors and nurses should recognition the system of social support, in order to improve the QOL of the patients.     

社会支持对肝硬化患者生活质量的影响研究

Objective To discuss the effect of social support to the quality of life of the patients with hepatocirrhosis. Methods 98 hepatocirrhosis patients in our hospital were divided into observation and control groups. Both the groups were accepted routine therapy and nursing while striving for social support for the patients of observation group, then having a whole evaluation to the status of patients, in the study early interference and health education were important. SSRE (Social Support Rating Scale) and SF - 36QOL made by America medi-cine graduate school to research and survey the two patients. Results The whole mark of social support (46.33 ±3.78) and the whole health of QOL (78.86±11.31 ) and every dimensionality of observation group were all bet-ter than those of control group (P<0.01) . Conclusions The social support can infect directly the QOL of pa-tients with hepatocirrhosis, all the doctors and nurses should recognition the system of social support, in order to improve the QOL of the patients.     

社会支持对肝硬化患者生活质量的影响研究

Objective To discuss the effect of social support to the quality of life of the patients with hepatocirrhosis. Methods 98 hepatocirrhosis patients in our hospital were divided into observation and control groups. Both the groups were accepted routine therapy and nursing while striving for social support for the patients of observation group, then having a whole evaluation to the status of patients, in the study early interference and health education were important. SSRE (Social Support Rating Scale) and SF - 36QOL made by America medi-cine graduate school to research and survey the two patients. Results The whole mark of social support (46.33 ±3.78) and the whole health of QOL (78.86±11.31 ) and every dimensionality of observation group were all bet-ter than those of control group (P<0.01) . Conclusions The social support can infect directly the QOL of pa-tients with hepatocirrhosis, all the doctors and nurses should recognition the system of social support, in order to improve the QOL of the patients.     

社会支持对肝硬化患者生活质量的影响研究

Objective To discuss the effect of social support to the quality of life of the patients with hepatocirrhosis. Methods 98 hepatocirrhosis patients in our hospital were divided into observation and control groups. Both the groups were accepted routine therapy and nursing while striving for social support for the patients of observation group, then having a whole evaluation to the status of patients, in the study early interference and health education were important. SSRE (Social Support Rating Scale) and SF - 36QOL made by America medi-cine graduate school to research and survey the two patients. Results The whole mark of social support (46.33 ±3.78) and the whole health of QOL (78.86±11.31 ) and every dimensionality of observation group were all bet-ter than those of control group (P<0.01) . Conclusions The social support can infect directly the QOL of pa-tients with hepatocirrhosis, all the doctors and nurses should recognition the system of social support, in order to improve the QOL of the patients.     

冲洗法用于经口气管插管患者口腔护理的效果评价

目的评价冲洗法用于经口气管插管患者口腔护理的效果，探讨经口气管插管患者合适的口腔护理方法。方法选取脑外科手术后需停留经口气管插管的患者150例，分为对照组73例与实验组77例，实验组采用冲洗法实施口腔护理，对照组实施传统的口腔护理方法。比较2组患者口腔异味、口腔湿润度及牙菌斑指数情况。结果实验组的口腔异味发生率、牙菌斑指数显著低于对照组；口腔湿润度显著高于对照组，2组比较差异有统计学意义，P〈0.01。结论口腔冲洗法能有效控制口腔异味，保持患者口腔湿润，有效抑制患者牙菌斑的形成。     

冲洗法用于经口气管插管患者口腔护理的效果评价

目的 评价冲洗法用于经口气管插管患者口腔护理的效果,探讨经口气管插管患者合适的口腔护理方法.方法 选取脑外科手术后需停留经口气管插管的患者150例,分为对照组73例与实验组77例,实验组采用冲洗法实施口腔护理,对照组实施传统的口腔护理方法.比较2组患者口腔异味、口腔湿润度及牙菌斑指数情况.结果 实验组的口腔异味发生率、牙菌斑指数显著低于对照组;口腔湿润度显著高于对照组,2组比较差异有统计学意义,P<0.01.结论 口腔冲洗法能有效控制口腔异味了保持患者口腔湿润,有效抑制患者牙菌斑的形成.     

幽门螺杆菌感染与非口源性口臭关系的研究

目的探讨幽门螺杆菌(Hp)感染与非口源性口臭的关系。方法选择无牙周疾病的口臭患者68例,健康对照组70例,进行13C呼气试验检测Hp感染情况;对Hp感染的口臭患者随机分为A、B两组,A组行三联方案根除Hp,B组不予根除Hp治疗,检查两组患者Hp及口臭的根除情况。结果 68例口臭患者的Hp阳性率为64.7%(44/68)。无口臭对照组有23例为Hp阳性,Hp阳性率为32.9%,差异具有统计学意义(P<0.01)。44例口臭患者随机分为两组,A组22例予根除Hp治疗,其中19例根除Hp成功,根除率为86.4%,根除Hp者口臭缓解18例,占94.7%。B组22例未予根除Hp治疗,同期复查口臭,缓解为2例,占9.1%,差异具有统计学意义(P<0.01)。结论幽门螺杆菌感染是非口源性口臭其中一个重要相关因素。     

一枝黄花含漱液防治全麻术后口臭的效果观察

目的探讨一枝黄花含漱液行口腔护理减少全麻术后患者发生口臭的可行性,提高患者的生活质量。方法采用随机抽样法将80例全麻下行腹腔镜胆囊切除术患者分成两组,每组40例。观察组采用一枝黄花含漱液进行口腔护理;对照组采用0．9％生理盐水进行常规口腔护理。比较两组患者口臭发生情况。结果观察组的口臭发生率明显低于对照组（P〈0．05）。结论一枝黄花含漱液行口腔护理可明显降低全麻术后患者口臭的发生。     

电动牙刷结合氧化电位水预防口腔插管病人感染的研究

目的寻找一种彻底、有效的适用于口腔气管插管病人的口腔护理方法,预防感染的发生。方法将80例外伤施行口腔气管插管病人,按随机化的原则分为观察组40例和对照组40例。观察组采用电动牙刷刷洗结合氧化电位水冲洗法进行口腔护理,对照组采用传统的口腔护理方法。观察2组病人口腔护理后口腔细菌株数、真菌感染情况及并发口臭、口腔炎、口腔溃疡有无差异性。结果2组病人口腔护理前细菌株数无差异,P>0.05;观察组口腔护理后比之前细菌数明显下降,P<0.01;对照组口腔护理后比之前细菌数明显下降,P<0.05;2组病人口腔护理后细菌数比较,观察组比对照组明显减少,P<0.01;细菌转阴株数观察组多于对照组,P<0.01。同时2组病人在并发口臭、口腔炎、口腔溃疡方面差异有显著性,P<0.05。结论采用电动牙刷刷洗结合氧化电位水冲洗法清洁口腔彻底、有效,能明显减少细菌数量,抑制细菌繁殖,防止口腔感染的发生。     

0.1%西吡氯铵含漱液治疗牙龈炎和抑制菌斑疗效及安全性的多中心随机双盲临床试验

目的 对0．1％西吡氯铵含漱液治疗牙龈炎和抑制菌斑的疗效及安全性进行评价。方法多中心随机、双盲、阳性药物对照、左右半口对照设计。首诊(D0)时对左侧上下牙齿洁治，结束时右侧洁治。两组均每日漱口5次，方法相同。从治疗前后临床及微生物学改变评价疗效，第4(D4)、8(D8)日复查。D0-D4停止刷牙，D4-D8恢复刷牙。结果 符合纳入标准144例，4例失访，试验组69例、对照组71例可进行分析。基线分析表明两组性别年龄分布、临床及微生物学指标均具有可比性。D4复查治牙侧两组菌斑累积量在同一水平并均显低于未治牙侧。两侧牙龈指数(GI)、出血指数(SBI)及口臭VAS记分均显低于基线值。D8复查两组菌斑指数(PI)、GI、SBI、口臭VAS比D4复查值进一步显减少，菌斑及唾液中可疑致病菌半数以上被清除，菌量显减少，但组间比较均无显差异，均未见菌群失调。试验组17例(24．6％)发生不良反应，均轻微一过性。体外抑菌实验证实试验药可杀灭或抑制多种与口咽、颌面部感染、牙龈炎、牙周炎、龋齿等有关的可疑致病菌。结论 西吡氯铵含漱液确能减少或抑制牙菌斑的形成、治疗牙龈炎、减少口臭，与国家已批准上市的西吡氯铵含漱液疗效相同。     

牙刷刷牙结合温开水冲洗在经口气管插管口腔护理中的应用效果观察

目的：探讨牙刷刷牙结合温开水冲洗在经口气管插管口腔护理中的应用效果。方法选取2012年5月-2013年6月在IC U监护治疗经口气管插管患者84例,随机将其分为实验组和对照组各42例。对照组采用生理盐水棉球进行口腔护理,实验组使用牙刷刷牙结合温开水冲洗方法进行口腔护理。比较2组患者的口腔护理应用效果。结果实验组口咽细菌、牙菌斑、口腔气味、住院时间、医疗费用、患者满意度情况均明显优于对照组。结论经口气管插管患者采用牙刷刷牙结合温开水冲洗进行口腔护理,可以有效清洁患者口腔、减少肺部细菌感染的发生。     

口泰含漱液预防重症病人口腔感染的效果观察

目的:观察口泰含漱液预防重症病人口腔感染的效果。方法:160例重症病人随机分为两组:实验组和对照组,每组各80例。实验组采用口泰含漱液含漱,2~3次/d,5~10 d为一疗程;对照组采用0.9%氯化钠注射液含漱,2~3次/d,5~10 d为一疗程。结果:实验组口腔感染率为6.25%,口臭率为15%;对照组口腔感染率为32.5%,口臭率为72.5%,两组比较,均有显著性差异(P均<0.05)。结论:应用口泰含漱液能有效降低口腔感染及口臭,避免口腔炎的发生,提高治疗效果。     

3种口腔护理液在神经科昏迷患者中的应用研究

目的 探讨3种口腔护理液在神经科昏迷患者中的运用效果。方法：选取南京医科大学附属脑科医院2019年2月至2019年7月神经科收治的90例昏迷患者，根据口腔护理液不同按随机数字表随机分为3组：中药组（使用中草药口腔护理液）、生理盐水组、银尔通组（使用银离子抗菌液）。3组均按常规口腔护理操作2次/日，共14天。比较3组患者干预前后的口腔PH值、口腔异味评分及满意度的差异性。结果 中药组、生理盐水组干预前后组内比较，口腔PH值有统计学差异（P＜0.01，P＜0.05），银尔通组干预前后组内比较，口腔PH值无统计学差异（P＞0.05）。三组不同时间点PH值相比较，无统计学差异（P＞0.05）。三组口腔异味评分干预前后组内比较，均有统计学差异（P＜0.01）。干预后第1天、第7天、第14天，中药组与生理盐水组、银尔通组口腔异味评分相比，有统计学差异（P＜0.05），生理盐水组与银尔通组相比无统计学差异（P＞0.05）。三组患者家属满意度无统计学差异（P＞0.05）。结论 中药口腔护理液去除口腔异味效果优于生理盐水和银离子抗菌液，值得临床推广和使用。     

Orem自理模式在经口气管插管患者口腔护理中的应用

为探讨Orem自理模式在经口气管插管患者口腔护理中的应用方法与效果,将Orem自理模式贯穿于护理的全过程,采用冲洗法进行口腔护理。患者术后恶心、咽喉干痛、口臭及口腔感染的发生率显著降低。