小儿麻醉临床分析研究

Objective To investigate the ketamine and propofol anesthesia for pediatric clinical effect.Methods From january 2009 to February 2010 in our hospital 80 cases surgery children were randomly divided into two groups of 37 cases of ketamine anesthesia using ketamine alone, 43 cases combined with propofol ketamine anesthesia to observe the postoperative incidence of adverse reactions, and postoperative recovery time,for statistical analysis. Results The preoperative and postoperative changes in HR and RR were better than the ketamine group, the difference was statistically significant, P＜ 0. 05; 9.3% adverse reaction rate in combined group was 24. 3% lower than the ketamine group,There were significant differences between groups, P ＜0. 05;recovery time in children of combimed group were less than ketamine group, the difference was also statistically significant, P＜ 0.05. Conclusion Ketamine and propofol anesthesia for children is better than a single ketamine anesthesia, should be widely applied.     

Incidence of adverse reactions to COVID-19 vaccination:A meta-analysis of randomized controlled trials

Objective:To systematically evaluate the incidence of adverse reactions to coronavirus disease 2019(COVID-19)vaccination.Methods:We systematically searched PubMed,Embase,The Cochrane Library,Web of Science,CNKI,WanFang Data,and VIP Database from the inception of each database to August 31,2021.Randomized controlled clinical trials(RCTs)on the safety of different types of COVID-19 vaccines were retrieved and analyzed.A random or fixed-effects model was used with an odds ratio as the effect size.The quality of each reference was evaluated.The incidence of the adverse reactions of the placebo group and the vaccination group was compared.Heterogeneity and publication bias were taken care of by meta-regression and sub-group analyses.Results:A total of 13 articles were included,with 81287 subjects.Compared with the placebo group,the vaccination group showed a higher combined risk ratio(RR)of total adverse reactions(RR=1.67,95%CI:1.46-1.91,P<0.01),local adverse reactions(RR=2.86,95%CI:2.11-3.87,P<0.01),systemic adverse reactions(RR=1.25,95%CI:0.92-1.72,P=0.16),pain(RR=2.55,95%CI:1.75-3.70,P<0.01),swelling(RR=4.16,95%CI:1.71-10.17,P=0.002),fever(RR=2.34,95%CI:1.84-2.97,P<0.01),fatigue(RR=1.36,95%CI:1.32-1.41,P<0.01)and headache(RR=1.22,95%CI:1.18-1.26,P<0.01).The subgroup analysis showed the incidence of adverse reactions of the vaccination group after injection of the three COVID-19 vaccines(inactivated viral vaccines,mRNA vaccines and adenovirus vector vaccines)was higher than that of the placebo group,and the difference between the placebo group and the vaccination group in the mRNA vaccine subgroup and the adenovirus vector vaccine subgroup was statistically significant(P<0.01).The incidence of adverse reactions after injection of COVID-19 vaccine in subgroups of different ages was significantly higher than that in the placebo group(P<0.01).Conclusions:COVID-19 vaccines have a good safety,among which adenovirus vector vaccine has the highest incidence of adverse reactions.Both adolescents and adults vaccinated with novel coronavirus vaccine have a certain proportion of adverse reactions,but the symptoms are mild and can be relieved by themselves.Our meta-analysis can help boost global awareness of vaccine safety,promote mass vaccination,help build regional and global immune barriers and effectively curb the recurrency of COVID-19.     

依布利特转复脑栓塞并心房纤颤的临床研究

Objective To judge the efficiency and safety of intravenous ibutilide for immediate cardioversion of recent-onset cerebral embolism and atrial fibrillation. Methods Fourty consecutive patients with atrial fibrillation(onset with in 1 h-90 d) and cerebral embolism were selected to the group. Patients received ibutilide 1 mg Ⅳ over 10 min. If atrial fibrillation persisted ten minutes later, repeat the first loading. Results The rate of cardioversion of the ibutilide group was high for up to 77.5%. The conversion rate was higher in patients whose atrial fibrillation had persisted within 24 h than over 24 h (89.29% vs 50%,P<0.05). The efficiency was higher in patients whose left atrial diameter was below 4.0 cm than that over 4.0 cm(92% vs 53.33%,P<0.05). The rate of conversion was related to degree and area of cerebral embolism. Diaorder of digestion is adverse drug reaction of ibutilide. The most serious adverse effect of ibutilide was nonsustained monomiphic yentricular tachycardia. Conclusion Ibutilide is a safe and effective agent cardioversion of recent-onset cerebral embolism and atrial fibrillation.     

依布利特转复脑栓塞并心房纤颤的临床研究

Objective To judge the efficiency and safety of intravenous ibutilide for immediate cardioversion of recent-onset cerebral embolism and atrial fibrillation. Methods Fourty consecutive patients with atrial fibrillation(onset with in 1 h-90 d) and cerebral embolism were selected to the group. Patients received ibutilide 1 mg Ⅳ over 10 min. If atrial fibrillation persisted ten minutes later, repeat the first loading. Results The rate of cardioversion of the ibutilide group was high for up to 77.5%. The conversion rate was higher in patients whose atrial fibrillation had persisted within 24 h than over 24 h (89.29% vs 50%,P<0.05). The efficiency was higher in patients whose left atrial diameter was below 4.0 cm than that over 4.0 cm(92% vs 53.33%,P<0.05). The rate of conversion was related to degree and area of cerebral embolism. Diaorder of digestion is adverse drug reaction of ibutilide. The most serious adverse effect of ibutilide was nonsustained monomiphic yentricular tachycardia. Conclusion Ibutilide is a safe and effective agent cardioversion of recent-onset cerebral embolism and atrial fibrillation.     

亚叶酸钙与碳酸氢钠含漱预防大剂量甲氨蝶呤致口腔溃疡的效果研究

目的 探讨亚叶酸钙与碳酸氢钠溶液交替含漱预防大剂量甲氨蝶呤所致口腔溃疡的效果.方法 将60例大剂量甲氨蝶呤化疗的患儿随机分为实验组及对照组,每组30例.对照组给予生理盐水含漱,实验组给予0.1%亚叶酸钙与1%碳酸氢钠溶液交替漱口.观察两组患者口腔溃疡发生率及溃疡发生程度.结果 实验组口腔溃疡发生率、程度明显低于对照组,两者比较差异有显著差异(P<0.01).结论 大剂量甲氨蝶呤化疗的患儿使用0.1%亚叶酸钙与1%碳酸氢钠溶液交替漱口,可以有效预防口腔溃疡的发生.

Abstract：

Objective To explore the effectiveness of preventing oral ulcer by using high dose methotrexate with calcium folinate and sodium bicarbonate gargle alternatively.Methods Sixty patients of high dose methotrexate chemotherapy were randomly divided into experiment group and control group, with 30 patients in each group, Normal saline was given to those in the control group for gargle, and calcium folinate and sodium bicarbonate gargle alternatively for those in the experiment group, The incidence and grade of oral ulcer were observed.Results The incidence of oral ulcer and grade were markedly lower in the experiment group than that in control group. The difference between the two groups was significant(P<0.01).Conclusions Alternate gargling with calcium folinate and sodium bicarbonate is effective in the prevention of incidence of oral ulcer in patients with high dose methotrexate chemotherapy.     

Effects of intracoronary injection of nicorandil and tirofiban on myocardial perfusion and short-term prognosis in elderly patients with acute ST-segment elevation myocardial infarction after emergency PCI

BACKGROUND:This study investigated the effects of the intracoronary injection of nicorandil and tirofiban on myocardial perfusion and short-term prognosis in elderly patients with acute ST-segment elevation myocardial infarction(STEMI)after emergency percutaneous coronary intervention(PCI).METHODS:Seventy-eight STEMI patients with age>65 years who underwent emergency PCI were consecutively enrolled.These patients received conventional PCI and were randomly divided into a control group and a treatment group(n=39 per group).The control group received an intracoronary injection of tirofiban followed by a maintenance infusion for 36 hours after surgery.The treatment group received intracoronary injection of tirofiban and nicorandil,and then intravenous infusion of tirofiban and nicorandil 36 hours after surgery.The following parameters were measured:TIMI grade,corrected TIMI frame count(c TFC),TIMI myocardial perfusion grade(TMPG),STsegment resolution(STR)rate 2 hours post-operatively,resolution of ST-segment elevation(STR)at 2 hours postoperatively,peak level of serum CK-MB,left ventricular end diastolic diameter(LVEDD)and left ventricular ejection fraction(LVEF)at 7–10 days postoperatively,and major adverse cardiac events(MACEs)in-hospital and within 30 days post-operatively.RESULTS:Compared with the control group,more patients in the treatment group had TIMI 3 and TMPG 3,and STR after PCI was significantly higher.The treatment group also had significantly lower c TFC,lower infarction relative artery(IRA),lower peak CK-MB,and no reflow ratio after PCI.The treatment group had significantly higher LVEDD and LVEF but lower incidence of MACEs than the control group.CONCLUSION:The intracoronary injection of nicorandil combined with tirofiban can effectively improve myocardial reperfusion in elderly STEMI patients after emergency PCI and improve shortterm prognoses.     

Clinical observation of soft palate-pharyngoplasty in the treatment of obstructive sleep apnea hypopnea syndrome in children

BACKGROUND Childhood obstructive sleep apnea hypopnea syndrome(OSAHS)is a common clinical disease that can cause serious complications if not treated in time.The preferred treatment for OSAHS in children is surgery.AIM To observe the effects of soft palate-pharyngoplasty on postoperative outcome,pharyngeal formation,and possible complications.METHODS A total of 150 children with snoring,hernia,and mouth breathing were selected.A polysomnography test was performed to confirm the diagnosis of OSAHS.The children were randomly divided into experimental and control groups.The experimental group underwent adenoidectomy,tonsillectomy,and soft palatepharyngoplasty.The control group underwent adenoidectomy and tonsillectomy.The t-test and chi-square test were used to compare conditions such as postoperative fever,postoperative hemorrhage,and pharyngeal reflux.Postoperative efficacy and complications were interrogated and observed in the form of outpatient follow-up and telephone follow-up at 6 mo and 1 year after surgery.The curative effects were divided into two groups:Cure(snoring,snoring symptoms disappeared)and non-cure.RESULTS The effective rate of the experimental group was significantly higher than that of the control group,but the difference was not statistically significant(P>0.05).The incidence of postoperative bleeding was lower in the experimental group.There was no postoperative pharyngeal reflux in either group.In the experimental group,the incidence of hyperthermia(body temperature exceeded 38.5°C)was lower than that in the control group.The difference in postoperative swallowing pain scores between the experimental and control groups was significant.CONCLUSION Soft palate-pharyngoplasty can more effectively enlarge the anteroposterior diameter and transverse diameter of the isthmus faucium.Compared with surgery alone,it can better treat OSAHS in children,improve the curative effect,reduce the risk of perioperative bleeding,close the surgical cavity,reduce the risk of postoperative infection,reduce the proportion of postoperative fever,and accelerate healing.Although this process takes more time,it is simple,safe,and effective.     

Clincal research of HA program combimed co-α-2b interferon on treatment of chronic myeloid leukemia

Objective To observe the HA program (3 harringtonine and Ara-C) co-α-2b interferon treatment of chronic myeloid leukemia in the feasibility and safety. Methods In our hospital from December 2005 to January 2009 out-patient and hospitalization in patients with CML were randomly assigned according to the principle of 51 cases were divided into 26 cases of the observation group and control group 25 cases. The control group were treated with α-2b interferon 3 × 106U subcutaneously or intramuscularly 3 times per week,intramuscularly 1 to 12 months to ease later changed to 2 times per week to maintain; treatment group therapy in the control group based on the GC small dose of HA programs: subcutaneous injection of Ara-C 20 mg,every 12 h one time; homoharringtonine alkaline 2 mg/d plus 5 % glucose solution 500 mL, by intravenous infusion over 4 h,in conjunction with the 7 ～ 14 d for a course of treatment monthly repeated a times, after 12 months depending on the circumstances every 2 to 3 months a time. Results The observation group and the control group,hematological remission total effective rates were 96.15% (25/26) and 72.0% (18/25),the observation group than the control group,2 group, the difference was significant (P<0.05); the observation group cytogenetic response overall response rates were 76.92% (20/26) and 20.0% (5 / 25), the observation group cytogenetic response overall response rate than the control group, 2 group, the difference was significant sex (P<0.05);two groups of patients with adverse reactions can be tolerated, does not affect the treatment. Conclusion Small dose of HA regimen combined with recombinant in terferon α-2b treatment of CML than single recombinant interferon α-2b high efficacy, with lower white blood cell effects of apparent high rate of hematologic response, no increase in adverse reactions and survival prolonged and so on.     

Clincal research of HA program combimed co-α-2b interferon on treatment of chronic myeloid leukemia

Objective To observe the HA program (3 harringtonine and Ara-C) co-α-2b interferon treatment of chronic myeloid leukemia in the feasibility and safety. Methods In our hospital from December 2005 to January 2009 out-patient and hospitalization in patients with CML were randomly assigned according to the principle of 51 cases were divided into 26 cases of the observation group and control group 25 cases. The control group were treated with α-2b interferon 3 × 106U subcutaneously or intramuscularly 3 times per week,intramuscularly 1 to 12 months to ease later changed to 2 times per week to maintain; treatment group therapy in the control group based on the GC small dose of HA programs: subcutaneous injection of Ara-C 20 mg,every 12 h one time; homoharringtonine alkaline 2 mg/d plus 5 % glucose solution 500 mL, by intravenous infusion over 4 h,in conjunction with the 7 ～ 14 d for a course of treatment monthly repeated a times, after 12 months depending on the circumstances every 2 to 3 months a time. Results The observation group and the control group,hematological remission total effective rates were 96.15% (25/26) and 72.0% (18/25),the observation group than the control group,2 group, the difference was significant (P<0.05); the observation group cytogenetic response overall response rates were 76.92% (20/26) and 20.0% (5 / 25), the observation group cytogenetic response overall response rate than the control group, 2 group, the difference was significant sex (P<0.05);two groups of patients with adverse reactions can be tolerated, does not affect the treatment. Conclusion Small dose of HA regimen combined with recombinant in terferon α-2b treatment of CML than single recombinant interferon α-2b high efficacy, with lower white blood cell effects of apparent high rate of hematologic response, no increase in adverse reactions and survival prolonged and so on.     

芬太尼透皮贴剂与盐酸哌替啶在恶性肿瘤患者术后镇痛中应用的效果评价及护理研究

目的 探讨比较芬太尼透皮贴剂与盐酸哌替啶在恶性肿瘤患者术后镇痛应用中的效果,并研究其护理方法.方法 选取2008年1月至2010年11月进行手术治疗的100例恶性肿瘤患者为研究对象,将其随机分为A组(芬太尼透皮贴剂组)和B组(盐酸哌替啶组)各50例,后将2组患者的术后2,4,8,24,48 h的VAS评分及不良反应发生率、患者满意度和手术前后的血清儿茶酚胺、糖皮质激素和血糖水平进行统计及比较,并对其采取相应的护理措施.结果 A组的术后2,4,8,24,48 h的VAS评分均优于B组,不良反应发生率低于B组,患者满意度高于B组,手术后血清儿茶酚胺、皮质醇和血糖水平均显著低于B组.结论 芬太尼透皮贴剂在恶性肿瘤患者术后镇痛应用中的效果更为稳定,广受患者好评,配合适当的护理效果明显.

Abstract：

Objective To study and compare the effects of Fentanyl transdermal pain patches and Pethidine in postoperative analgesia of malignant tumor and its nursing methods.Methods 100 patients with malignant tumor in our hospital from January 2008 to November 2010 were selected as research object,all the patients were randomly divided into group A (Fentanyl transdermal pain patches group) and group B (Pethidine group)with 50 cases in each group,then the VAS score 2,4,8,24 and 48h after the surgery,incidence of adverse reactions,satisfaction rate and serum catecholamine,cortisol,blood glucose before and after the surgery were analyzed and compared,and all the patients were given corresponding nursing measures.Results The VAS score of group A at 2,4,8,24 and 48h after the surgery were all better than those of group B,incidence of adverse reactions was lower than that of group B,satisfaction rate was higher than that of group B,serum catecholamine,cortisol,blood glucose after the surgery were all lower than those of group B,there were significant differences.Conclusions The effects of Fentanyl transdermal pain patches in postoperative analgesia of malignant tumor is stable,and it gets good reputation from the patients,the effects is obvious combined with nursing.     

静脉留置针在小儿输注不同浓度葡萄糖酸钙中的应用效果比较

目的：探讨婴幼儿静脉留置针输注葡萄糖酸钙时的药物最佳稀释浓度和静脉留置针留置时间。方法选择需要静脉补钙的患儿139例，按随机数字表法分为等倍稀释组43例，2倍稀释组48例和5倍稀释组48例，均使用静脉留置针，比较各组患儿穿刺血管外渗性损伤发生率、损伤程度和愈后情况。结果等倍稀释组、2倍稀释组、5倍稀释组患儿静脉留置针穿刺血管3d累计发生外渗率分别为19．4％，9．0％，2．1％，差异有统计学意义（H＝261．23，P＜0．01）；进一步两两比较，等倍稀释组发生血管外渗率高于2倍稀释组（χ2＝6．88，P＜0．01），2倍稀释组高于5倍稀释组（χ2＝6．40，P＜0．05），等倍稀释组高于5倍稀释组（χ2＝20．48，P＜0．01）。留置针在第1天，第2天，第3天血管外渗率比较差异无统计学意义（H＝3．47，P＞0．05）。结论运用静脉留置针对婴幼儿进行补钙时，10％葡萄糖酸钙稀释5倍时外渗性损伤发生率最低。     

Effectiveness of supplemental oral calcium drink in preventing citrate-related adverse effects in peripheral blood progenitor cell collection

Peripheral blood progenitor cells (PBPCs) are a predominant graft source in allogeneic hematopoietic cell transplantation. Citrate-induced hypocalcemia remains the most frequent side effect of PBPC apheresis. Although the method for preventing severe adverse events is established, more efficient prophylaxis is required so that volunteer donors can donate PBPCs without pain and anxiety. We studied 80 healthy donors who underwent PBPC harvest between February 2014 and June 2020. Of these, 23 donors who underwent apheresis between February 2014 and December 2015 received only the standard prophylaxis of intravenous calcium gluconate. Oral calcium drinks were provided to 57 donors who underwent apheresis from January 2016 to June 2020 to supplement intravenous calcium gluconate prophylaxis. The ionized calcium (ICa) levels at multiple time intervals and the hypocalcemic symptoms were evaluated. Oral supplementation with a calcium drink maintained significantly higher ICa levels. Analysis using the inverse probability weighted regression adjustment method suggested that calcium drinks reduced the frequency of citrate-related reactions by 39.2 %. Administering a prophylactic oral calcium drink before apheresis with intravenous administration of calcium gluconate is promising to further reduce citrate-induced hypocalcemia in volunteer donors.     

肿瘤患者血细胞分离治疗中不同补钙时机与方式的探讨

目的探讨在血细胞分离过程中,葡萄糖酸钙用药的最佳时机和方式。方法将216例行血细胞分离患者随机分成两组,观察组108例在分离血细胞开始前采取匀速、低浓度补钙法,即将10%葡萄糖酸钙10 ml用生理盐水40 ml稀释成50 ml溶液,用4号针头静脉注射;对照组108例,采用随机补钙法,给药时机主要在血细胞分离进行中,抽取10%葡萄糖酸钙10 ml,用8号针头缓慢静脉注射。两组静脉注射时间均为6 min,观察、询问并记录患者的感受与不适。结果观察组发生不良反应4例次,即头痛头晕、恶心呕吐、胸闷心慌、口周麻木各1例次,对照组发生不良反应共53例次,分别为头痛头晕10例次、恶心呕吐4例次、胸闷心慌13例次、喉咙及全身发热16例次,口周麻木10例次,两组间差异有统计学意义（P〈0.01）。结论在细胞分离前采取匀速、低浓度静脉给药方法补钙,能减少各种不良反应的发生,提高患者在分离过程中安全性和舒适度。     

前列腺素E1两种给药方法治疗心力衰竭效果观察

目的比较前列腺素E1（凯时）两种给药方法治疗心力衰竭的效果及不良反应。方法将100例心力衰竭患者随机分为A组和B组,各50例。A组采用生理盐水100ml＋凯时10μg静脉输注,30~40滴/min,B组采用生理盐水20ml＋凯时10μg静脉推注或静脉输注。比较两组治疗效果及不良反应发生率。结果两组心率、血压治疗前后比较无显著性差异（P〉0.05）。A组不良反应为26%,B组不良反应为6%,两组比较有显著性差异（P〈0.05）。且缩短了治疗时间,依从性好。结论采用生理盐水20ml＋凯时10μg静脉推注或静脉输注的给药方法治疗心力衰竭可以在临床应用。     

温度对60%泛影葡胺毒副反应的影响

目的:探讨温度对60%泛影葡胺毒副反应的影响。方法:将330例拟行CT增强扫描患者随机分为观察组170例和对照组160例,观察组行CT检查时将60%泛影葡胺加热至37℃后静脉注射,对照组静脉注射常温60%泛影葡胺,观察造影剂在不同温度下黏稠度及两组静脉注射造影剂后毒副反应发生率。结果:随温度升高,造影剂黏稠度下降,观察组毒副反应发生率与对照组比较差异有统计学意义(P<0.05)。结论:静脉注射前适当提高泛影葡胺温度对增加患者对造影剂的耐受性、降低毒副反应发生率效果确切。     

4种糖皮质激素疗法治疗慢性阻塞性肺疾病患者突发喘累的效果比较

目的探讨4种常用的糖皮质激素疗法治疗慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者突发喘累的效果差异。方法住院治疗期间突发喘累症状的COPD患者156例,在进行临时平喘治疗时,A组41例使用地塞米松联合氨茶碱静脉推注,B组37例使用甲基强的松龙静脉推注,C组40例使用甲基强的松龙快速静脉滴注,D组38例使用氢化可的松快速静脉滴注。以药物起效时间、用药后第1、2、3小时后患者症状的改善情况及不良反应作为考察指标。结果各组患者的症状均有改善。A组药物起效时间明显少于另外3组,症状改善程度及不良反应发生率均显著高于另外3组。D组药物起效时间显著长于另外3组,症状改善程度显著低于另外3组。B组与C组之间上述各项指标无明显差异,均介于A组与D组之间。结论地塞米松联合氨茶碱静脉推注起效最快,平喘效果最强,但不良反应发生率最高。氢化可的松静脉滴注起效最慢,平喘效果亦最弱。甲基强的松龙起效时间及平喘效果均居中,且静脉推注与滴注效果相似。     

长期多频次机采献血者体内钙磷代谢变化及口服葡萄糖酸钙改善柠檬酸盐抗凝剂不良反应的护理研究

目的：调查研究深圳市长期多频次机采献血者体内钙磷代谢变化及口服葡萄糖酸钙改善柠檬酸盐抗凝剂不良反应护理。方法采用随机数字表法将56例献血者按照含有口服葡萄糖酸钙的方式,分为采集前补钙组20例,采集中补钙组19例,未补钙组17例。结果跟踪观察三组献血者的血清钙水平、磷水平以及PTH水平,均出现不同变化。在采集后60 min中未补钙组中血清PTH为（160.23±29.76）pg／ml,采集中补钙组为（121.75±43.12）pg／ml,采集前补钙组为（104.75±20.99）pg／ml,三者相比差异有统计学意义（ P＜0.05）。结论献血者机采前10 min口服葡萄糖酸钙,是补充钙剂的最佳时机,有利于改善献血者低钙症状,提高机采过程中的舒适度,确保献血安全。     

精神科急诊分诊标准化问诊流程的应用效果观察

目的探讨精神科急诊分诊标准化问诊流程在临床实践中的应用效果。方法选择2018年3-5月就诊的精神科急诊患者96例作为对照组,采用常规问诊流程;选择2019年3-5月就诊的精神科急诊患者104例作为观察组,采用精神科急诊分诊标准化问诊流程。比较两组患者急诊停留时间、住院时间、镇静药物使用次数、急诊期间严重不良事件发生率及家属满意度。结果观察组急诊停留时间、住院时间短于对照组,镇静药物使用次数少于对照组,差异具有统计学意义(P<0.05);观察组患者家属满意度高于对照组,差异具有统计学意义(P<0.05);观察组患者急诊期间自伤、伤害医护人员等不良事件发生率低于对照组,差异具有统计学意义(P<0.05)。结论精神科急诊分诊标准化问诊流程能够有效缩短急诊停留时间、住院时间,降低镇静药物使用次数,降低不良事件发生率,提升家属满意度。     

小剂量艾司氯胺酮对无痛胃肠镜检查时丙泊酚联合瑞芬太尼麻醉效果的影响

目的 观察无痛胃肠镜检查时小剂量艾司氯胺酮对丙泊酚联合瑞芬太尼静脉麻醉效果的影响,判断其减少呼吸抑制的可行性.方法 选择2021年3月至6月在南通大学附属南京江北医院行无痛胃肠镜检查的患者100例,男女不限,18～65岁,BMI＜30,ASA分级Ⅰ～Ⅱ级.将患者随机分为艾司氯胺酮组(静脉给予艾司氯胺酮0.1 mg/kg...     

Treatment of hydrofluoric acid burn to the face by carotid artery infusion of calcium gluconate

Hydrofluoric acid (HF) is highly corrosive substance often used in industrial processes. HF burns to the skin cause local tissue injury. Systemic hypocalcemia may ensue, with the potential to produce life-threatening arrhythmias. Medical treatment consists of local application of topical calcium gels, subcutaneous injection of calcium gluconate, and intravenous or intra-arterial infusion of calcium gluconate. Calcium gluconate infusions have been used for HF burns on distal extremities and digits. We report a case of HF burn to the face that was treated by the use of calcium gluconate infusion via the external carotid artery.