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《Anales de pediatría (Barcelona, Spain : 2003)》2014,80(1):52.e1-52.e14
Hypothermia treatment for newborn infants with hypoxic-ischemic encephalopathy reduces the number of neonates who die or have permanent neurological deficits. Although this therapy is now standard of care, neonatal hypoxic-ischaemic encephalopathy still has a significant impact on the child's neurodevelopment and quality of life. Infants with hypoxic-ischaemic encephalopathy should be enrolled in multidisciplinary follow-up programs in order to detect impairments, to initiate early intervention, and to provide counselling and support for families.This article describes the main neurodevelopmental outcomes after term neonatal hypoxic-ischaemic encephalopathy. We offer recommendations for follow-up based on the infant's clinical condition and other prognostic indicators, mainly neonatal neuroimaging. Other aspects, such as palliative care and medico-legal issues, are also briefly discussed. 相似文献
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Laura García Alonso Marcelino Pumarada Prieto Eva González Colmenero Ana Concheiro Guisán María Suárez Albo Cristina Durán Fernández-Feijoo Luisa González Durán José Ramón Fernández Lorenzo 《Anales de pediatría (Barcelona, Spain : 2003)》2017,86(3):135-141
Introduction
Antenatal magnesium sulphate (MgSO4) administration has shown to be effective in minimising cerebral palsy and severe motor dysfunction at the age of 2 years.The aim of this study is to analyse the initial clinical outcome of preterm neonates less than 29 weeks who have received prenatal MgSO4, as well as to determine the relationship between the magnesium dose delivered to the mother and the magnesium concentration in the neonates.Material and methods
A prospective cohort study was conducted on neonates of less than 29 weeks gestation admitted to the Neonatal Intensive Care Unit (NICU) of Hospital Universitario de Vigo from December 2012 to July 2015. Comparative analysis was performed on the perinatal outcomes, neonatal morbidity, mortality, and magnesium levels between the groups of neonates exposed to magnesium sulphate and the control group.Results
A total of 42 neonates were included in the study. The mothers of 28 of them had received MgSO4 as a neuroprotective agent.Statistical significance was obtained in the mortality variable. There were no significant differences in the rest of studied variables. There was a significant correlation between the full dose of MgSO4 received by the mother and the levels of magnesium in the neonate in the first 24 hours of life (r2 0.436; P<.001).Conclusions
A lower mortality was observed in the group that had been exposed to MgS04. No significant side effects were found as a result of administering of MgS04. The MgS04 dose received by mother has a linear relationship with the magnesium levels obtained in neonates. 相似文献8.
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V. Trenchs Sainz de la Maza A.I. Curcoy Barcenilla G. Gelabert Colome C. Macias Borras J. Pou Fernández 《Anales de pediatría (Barcelona, Spain : 2003)》2013,78(2):118-122
AimTo measure the incidence of admissions for maltreatment between 1995 and 2009 and to determine their main clinical and epidemiological characteristics.MethodsRetrospective review of children diagnosed with maltreatment over 15years in a third level hospital.ResultsA total of 97 cases (median incidence 0.5 cases per 1000 children admitted per year) were found. There was an increasing rate of physical maltreatment, while those of sexual abuse declined. 51 (53.6%) female; median age 3.3 years (p25-75: 7.6 months-10.0 years). Just under half (43.3%) or 42 patients, had a primary complaint unrelated to abuse. The most common injuries were haematomas (43; 44.3%). In 91 (93.8%) cases the perpetrator was found to be a member of the child's own family (77; 74.9%, one of the parents or both).ConclusionsThe increase in admissions for physical maltreatment stresses the need to insist in a prevention policy. The decrease in admissions for sexual abuse was probably attributable to changes in the care circuit rather than a real decrease. In almost half of the cases the suspicion of maltreatment arose upon physical examination or after complementary tests, making it advisable that maltreatment is included in the differential diagnosis in multiple consultations. The majority of maltreatment occurred in the context of the victim's family. 相似文献
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Víctor Soto Insuga Beatriz Moreno Vinués Rebeca Losada del Pozo María Rodrigo Moreno Marta Martínez González Raquel Cutillas Ruiz Carmen Mateos Carmen 《Anales de pediatría (Barcelona, Spain : 2003)》2018,88(4):191-195