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1.
Drilling large holes (e.g., 10–20?mm diameter) into concrete for structural upgrades to buildings, highways, bridges, and airport runways can produce concentrations of respirable silica dust well above the ACGIH® Threshold Limit Value (TLV® = 0.025?mg/m3). The aim of this study was to evaluate a new method of local exhaust ventilation, hollow bit dust extraction, and compare it to a standard shroud local exhaust ventilation and to no local exhaust ventilation. A test bench system was used to drill 19?mm diameter x 100?mm depth holes every minute for one hour under three test conditions: no local exhaust ventilation, shroud local exhaust ventilation, and hollow bit local exhaust ventilation. There were two trials for each condition. Respirable dust sampling equipment was placed on a “sampling” mannequin fixed behind the drill and analysis followed ISO and NIOSH methods. Without local exhaust ventilation, mean respirable dust concentration was 3.32 (±?0.65) mg/m3 with a quartz concentration of 16.8% by weight and respirable quartz dust concentration was 0.55 (±?0.05) mg/m3; 22 times the ACGIH TLV. For both LEV conditions, respirable dust concentrations were below the limits of detection. Applying the 16.8% quartz value, respirable quartz concentrations for both local exhaust ventilation conditions were below 0.007?mg/m3. There was no difference in respirable quartz dust concentrations between the hollow bit and the shroud local exhaust ventilation systems; both were below the limits of detection and well below the ACGIH TLV. Contractors should consider using either local exhaust ventilation method for controlling respirable silica dust while drilling into concrete.  相似文献   

2.
The objective of this study was to quantify the respirable dust and respirable silica exposures of roofing workers using an electric-powered circular saw with an aftermarket local exhaust ventilation attachment to cut concrete roofing tiles. The study was conducted to determine whether the local exhaust ventilation attachment was able to control respirable dust and respirable silica exposure below occupational exposure limits (OELs). Time-integrated filter samples and direct reading respirable dust concentrations were evaluated. The local exhaust ventilation consisted of a shroud attached to the cutting plane of the saw; the shroud was then connected to a small electric axial fan, which is intended to collect dust at the point of generation. All sampling was conducted with the control in use.

Roofers are defined as those individuals who only lay tiles. Cutters/roofers are defined as those workers who operate the powered saw to cut tiles and also lay tiles. Respirable dust from this evaluation ranged from 0.13 to 6.59 milligrams per cubic meter (mg/m3) with a geometric mean of 0.38 mg/m3 for roofers and from 0.45 to 3.82 mg/m3 with a geometric mean of 1.84 mg/m3 for cutters/roofers. Cutters/roofers usually handle areas close to crevices, edges, or tips of the roof whereas roofers handle areas where complete tiles can be placed. The respirable dust exposures for all cutters/roofers indicated concentrations exceeding the Occupational Safety and Health Administration's (OSHA) permissible exposure limit (PEL) for respirable dust containing silica; it was also exceeded for some of the roofers. The respirable silica concentrations ranged from 0.04 to 0.15 mg/m3 with a geometric mean of 0.09 mg/m3 for roofers, and from 0.13 to 1.21 mg/m3 with a geometric mean of 0.48 mg/m3 for cutters/roofers. As with respirable dust, the respirable silica exposures for cutters/roofers were higher than the exposures for roofers.  相似文献   


3.
Although crystalline silica has been recognized as a health hazard for many years, it is still encountered in many work environments. Numerous studies have revealed an association between exposure to respirable crystalline silica and the development of silicosis and other lung diseases including lung cancer. Alberta Jobs, Skills, Training and Labour conducted a project to evaluate exposure to crystalline silica at a total of 40 work sites across 13 industries. Total airborne respirable dust and respirable crystalline silica concentrations were quite variable, but there was a potential to exceed the Alberta Occupational Exposure Limit (OEL) of 0.025 mg/m3 for respirable crystalline silica at many of the work sites evaluated. The industries with the highest potentials for overexposure occurred in sand and mineral processing (GM 0.090 mg/m3), followed by new commercial building construction (GM 0.055 mg/m3), aggregate mining and crushing (GM 0.048 mg/m3), abrasive blasting (GM 0.027 mg/m3), and demolition (GM 0.027 mg/m3). For worker occupations, geometric mean exposure ranged from 0.105 mg/m3 (brick layer/mason/concrete cutting) to 0.008 mg/m3 (dispatcher/shipping, administration). Potential for GM exposure exceeding the OEL was identified in a number of occupations where it was not expected, such as electricians, carpenters and painters. These exposures were generally related to the specific task the worker was doing, or arose from incidental exposure from other activities at the work site. The results indicate that where there is a potential for activities producing airborne respirable crystalline silica, it is critical that the employer include all worker occupations at the work site in their hazard assessment. There appears to be a relationship between airborne total respirable dust concentration and total respirable dust concentrations, but further study is require to fully characterize this relationship. If this relationship holds true, it may provide a useful hazard assessment tool for employers by which the potential for exposure to airborne respirable silica at the work site can be more easily estimated.  相似文献   

4.
In 1974, the National Institute for Occupational Safety and Health recommended a ban on the use of abrasives containing >1% silica, giving rise to abrasive substitutes like copper slag. We present results from a National Institute for Occupational Safety and Health industrial hygiene survey at a copper slag processing facility that consisted of the collection of bulk samples for metals and silica; and full-shift area and personal air samples for dust, metals, and respirable silica.

Carcinogens, suspect carcinogens, and other toxic elements were detected in all bulk samples, and area and personal air samples. Area air samples identified several areas with elevated levels of inhalable and respirable dust, and respirable silica: quality control check area (236 mg/m3 inhalable; 10.3 mg/m3 respirable; 0.430 mg/m3 silica), inside the screen house (109 mg/m3 inhalable; 13.8 mg/m3 respirable; 0.686 mg/m3 silica), under the conveyor belt leading to the screen house (19.8 mg/m3 inhalable), and inside a conveyor access shack (11.4 mg/m3 inhalable; 1.74 mg/m3 respirable; 0.067 mg/m3 silica). Overall, personal dust samples were lower than area dust samples and did not exceed published occupational exposure limits. Silica samples collected from a plant hand and a laborer exceeded the American Conference of Governmental Industrial Hygienist Threshold Limit Value of 0.025 µg/m3. All workers involved in copper slag processing (n = 5) approached or exceeded the Occupational Safety and Health Administration permissible exposure limit of 10 µg/m3 for arsenic (range: 9.12–18.0 µg/m3). Personal total dust levels were moderately correlated with personal arsenic levels (Rs = 0.70) and personal respirable dust levels were strongly correlated with respirable silica levels (Rs = 0.89).

We identified multiple areas with elevated levels of dust, respirable silica, and metals that may have implications for personal exposure at other facilities if preventive measures are not taken. To our knowledge, this is the first attempt to characterize exposures associated with copper slag processing. More in-depth air monitoring and health surveillance is needed to understand occupational exposures and health outcomes in this industry.  相似文献   


5.
OBJECTIVES—To investigate the risk of silicosis among tin miners and to investigate the relation between silicosis and cumulative exposure to dust (Chinese total dust and respirable crystalline silica dust).
METHODS—A cohort study of 3010 miners exposed to silica dust and employed for at least 1 year during 1960-5 in any of four Chinese tin mines was conducted. Historical total dust data from China were used to create a job exposure matrix for facility, job title, and calendar year. The total dust exposure data from China were converted to estimates of exposure to respirable crystalline silica for comparison with findings from other epidemiological studies of silicosis. Each worker''s work history was abstracted from the complete employment records in mine files. Diagnoses of silicosis were based on 1986 Chinese pneumoconiosis Roentgen diagnostic criteria, which classified silicosis as stages I-III—similar to an International Labour Organisation (ILO) classification of 1/1 or greater.
RESULTS—There were 1015 (33.7%) miners identified with silicosis, who had a mean age of 48.3 years, with a mean of 21.3 years after first exposure (equivalent to 11.0 net years in a dusty job). Among those who had silicosis, 684 miners (67.4%) developed silicosis after exposure ended (a mean of 3.7 years after). The risk of silicosis was strongly related to cumulative exposure to silica dust and was well fitted by the Weibull distribution, with the risk of silicosis less than 0.1% when the Chinese measure of cumulative exposure to total dust (CTD) was under 10 mg/m3-years (or 0.36 mg/m3-years of respirable crystalline silica), increasing to 68.7% when CTD exposure was 150 mg/m3-years (or 5.4 mg/m3-years of respirable crystalline silica). Latency period was not correlated to the risk of silicosis or cumulative dose of exposure. This study predicts about a 36% cumulative risk of silicosis for a 45 year lifetime exposure to these tin mine dusts at the CTD exposure standard of 2 mg/m3, and a 55% risk at 45 years exposure to the current United States Occupational Safety and Health Administration and Mine Safety and Health Administration standards of 0.1 mg/m3 100% respirable crystalline silica dust.
CONCLUSIONS—A clear exposure-response relation was detected for silicosis in Chinese tin miners. The study results were similar to most, but not all, findings from other large scale exposure-response studies.


  相似文献   

6.
The cleanup effort following the destruction of the World Trade Center (WTC) was unprecedented and involved removal of 1.8 million tons of rubble over a nine-month period. Work at the site occurred 24 hr a day, 7 days a week and involved thousands of workers during the process. The Occupational Safety and Health Administration (OSHA) conducted personal and area exposure sampling during the cleanup of the site. Secondary data analysis was performed on OSHA air sampling data for respirable dust and silica from September 2001 to June 2002 at the WTC recovery site to characterize workers' exposure. Results for silica and respirable particulate were stratified by area and personal samples as well as job task for analysis. Of 1108 samples included in the analysis, 693 were personal and 415 were area. The mean result for personal silica samples was 42 μg/m3 (Range: 4.2–1800 μg/m3). Workers identified as drillers had the highest mean silica exposure (72 μg/m3; range: 5.8–800 μg/m3) followed by workers identified as dock builders (67 μg/m3; range: 5.8–670 μg/m3). The mean result for personal samples for respirable particulate was 0.44 mg/m3 (range: 0.00010–13 mg/m3). There were no discernable trends in personal respirable dust and silica concentrations with date.  相似文献   

7.
A comprehensive survey of respirable dust and respirable silica in Ontario gold mines was conducted by the Ontario Ministry of Labor during 1978–1979. The aim was to assess the feasibility of introducing gravimetric sampling to replace the assessment method which used konimeters, a device which gave results in terms of number of particles per cubic centimeter (ppcc) of air. The study involved both laboratory and field assessments. The field assessment involved measurement of airborne respirable dust and respirable silica at all eight operating gold mines of the time. This article describes the details of the field assessment. A total of 288 long-term (7–8 hr) personal respirable dust air samples were collected from seven occupational categories in eight gold mines. The respirable silica (α-quartz) was determined by x-ray diffraction method. The results show that during 1978–1979, the industry wide mean respirable dust was about 1 mg/m3, and the mean respirable silica was 0.08 mg/m3.The mean% silica in respirable dust was 7.5%. The data set would be useful in future epidemiological and health studies, as well as in assessment of workers’ compensation claims for occupational diseases such as silicosis, chronic obstructive pulmonary disease (COPD), and autoimmune diseases such as renal disease and rheumatoid arthritis.  相似文献   

8.
Exposures to British Mining Research Establishment corrected respirable dust and respirable quartz at U.S. surface coal mines during 1982–1983 were evaluated from coal mine operator and Mine Safety and Health Administration (MSHA) inspector samples. The average respirable quartz concentration from inspector samples ranged from .34-.49 mg/m3 for drilling jobs and .18 mg/m3 for bulldozer operators. For most other surface coal mine jobs, the average respirable quartz concentration was less than .1 mg/m3, and the average respirable dust concentration was less than 2 mg/m3. The results from the analysis of quartz exposures are consistent with epidemiological results for an increased silicosis risk among drillers. It is unclear, however, whether the MSHA samples provide a representative estimate of the average annual quartz concentration for drillers. Results suggest the need for a greater number of quartz samples to be taken on strip coal miners, particularly on drillers and bulldozer operators.  相似文献   

9.
Objectives: The effects of cement dust exposure on acute respiratory health were assessed among 51 high exposed and 33 low exposed male cement workers. The ability of the questionnaire to diagnose acute decrease in ventilatory function was also assessed. Methods: Acute respiratory symptoms were recorded by interview using a structured optimal symptom score questionnaire. Peak expiratory flow (PEF) was measured preshift and postshift for each worker with a Mini-Wright PEF meter. Personal respirable dust (n=30) and total dust (n=15) were measured with 37-mm Cyclone and 37-mm closed-faced Millipore cassette. Twenty-nine workers had concurrent respirable dust, PEF and questionnaire on the same day. Results: The geometric means of personal respirable dust and total dust among high exposed were 4.0 and 13.2 mg/m3, respectively, and 0.7 and 1.0 mg/m3 among low exposed. High exposed workers had more acute cough, shortness of breath and stuffy nose than the low exposed. Mean percentage cross-shift decrease in PEF was significantly more pronounced among high exposed workers than low exposed (95% CI 1.1, 6.1%). For workers with concurrent respirable dust, PEF and questionnaire assessment, an exposure–response relationship was found between log-transformed respirable dust and percentage cross-shift decrease in PEF (4.5% per unit of log-respirable dust in mg/m3 ; 95% CI 3.3, 5.6%). Respirable dust exposure ≥2.0 mg/m3 versus <2.0 mg/m3 was associated with increased prevalence ratio for cough (7.9) and shortness of breath (4.2). Shortness of breath was associated with the highest sensitivity (0.87) and specificity (0.83) for diagnosing a percentage cross-shift decrease in PEF of ≥10%. Conclusion: The observed acute respiratory health effects among the workers are most likely due to exposure to high concentrations of irritant cement dust. The results also highlight the usefulness of the questionnaire for health surveillance of the acute respiratory health effect.  相似文献   

10.
A quantitative retrospective exposure assessment method was developed for use in a nested case-control study of lung cancer among mine and pottery workers exposed to silica dust in the People's Republic of China. Exposure assessment was carried out in 20 mines (10 tungsten, 6 iron/copper, and 4 tin) and nine pottery factories. A job title dictionary was developed and used in both the collection of historical exposure information and work histories of 1,668 (316 cases and 1,352 controls) study subjects. Several data abstraction forms were developed to collect historical and current exposure information and employees' work histories, starting in 1950. A retrospective exposure matrix was developed on the basis of facility/job title/calendar year combinations using available historical exposure information and current exposure profiles. Information on the amount of respirable, thoracic, and free silica content in total dust was used in estimating exposure to silica. Starting in 1950, 6,805 historical estimates had been carried out for 14 calendar-year periods. We estimated the average total dust concentration to be 9 mg/M3, with a range from 28 mg/M3 in earlier years to 3 mg/M3 in recent years. Several exposure indices [such as cumulative dust, average dust, cumulative respirable (<5 μ in particle size) and thoracic (<10 μ in particle size) silica dust, average respirable and thoracic silica dust, exposure-weighted duration, and the highest/longest exposure] were calculated for individuals by merging work history and historical exposure matrix for each study subject. We developed these various measures of exposure to allow investigators to compare and contrast different indices of historical exposure to silica. © 1993 Wiley-Liss, Inc.
  • 1 This article is a US Government work and, as such, is in the public domain in the United States of America.
  •   相似文献   

    11.
    Quantitative estimates of dust exposure in a diatomaceous earth (DE) mining and milling operation have been derived based on air sampling records for the period 1948–1988. A total of 6395 records was included in the analysis. Conversion of results obtained by particle counting, expressed as millions of particles per cubic feet (mppcf) or gravimetrically from a filter cassette and expressed as mg m−3 total, were converted to mg m−3 respirable dust using a conversion factor derived from data obtained during the same periods at the plant. Conversion factors were calculated as the average difference of means on the log scale in order to provide stable and consistent conversions and as a ratio of arithmetic means so that the results could be compared with similar studies. After converting the available data to mg m−3 respirable dust, geometric mean (geometric standard deviation) concentrations were 0.37 (2.43) during the 1950s and 0.17 (2.35) during later periods. Exposures were estimated using two linear models, one estimating the changes in concentration over time, and the other providing job-specific mean exposures during the more recent period. Extrapolation of the estimates to periods prior to the availability of any data was done using a subjectively-determined scaling factor. The average estimated respirable dust concentrations for 135 jobs were 3.55 (±1.25), 1.37 (±0.48), 0.47 (±0.16) and 0.29 (±0.10) mg m−3 prior to 1949, 1949–1953, 1954–1973 and 1974–1988, respectively. Despite the limitations of the available data, the estimation procedures used are expected to provide reasonable quantitative estimates of silica-containing dust exposure for subsequent exposure-response analyses.  相似文献   

    12.
    Objectives To describe the relationship between cumulative respirable dust and quartz exposure and lung functioning among workers in a labour-intensive coal mine. Methods The study population comprised 299 men working at a coal mine in Tanzania. Lung function was assessed using a Vitalograph alpha III spirometer in accordance with American Thoracic Society recommendations. Multiple linear regression models were developed to study the relationship between forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC and the cumulative dust or quartz exposure while adjusting for age, height and ever smoking. To evaluate trends for dose response, cumulative exposure concentrations for respirable dust and quartz were ranked and categorized in quartiles and the highest decile, with the first quartile as the reference group. Logistic regression models were used to determine odds ratios for FEV1/FVC < 0.7 and FEV1% < 80 for categories of cumulative dust or quartz exposure. Results The prevalence of FEV1/FVC < 0.7 among the workers was 17.3%. Workers in the development team (20.5%) had the highest prevalence of FEV1% < 80%. The estimates of the effects of cumulative exposure on FEV1/FVC were −0.015% per mg years m–3 for respirable dust and –0.3% per mg years m–3 for respirable quartz. In logistic regression models, the odds ratios for airway limitation (FEV1/FVC < 0.7) for the workers in the highest decile of cumulative dust and quartz exposure versus the referents were 4.36 (95% confidence interval: 1.06, 17.96) and 3.49 (0.92, 13.21), respectively. The upper 10% of workers by cumulative dust and quartz exposure also had higher odds ratios for predicted FEV1% < 80% than the reference group odds ratio: 10.38 (1.38, 78.13) and 14.18 (1.72, 116.59), respectively. The results must be interpreted with caution due to a possible healthy worker effect and selection bias. Conclusion Exposure to respirable coal mine dust was associated with airway limitation as measured by FEV1/FVC and predicted FEV1%.  相似文献   

    13.
    We investigated exposure-response relations for silicosis among 134 men over age 40 who had been identified in a previous community-based random sample study in a mining town. Thirty-two percent of the 100 dust-exposed subjects had radiologic profusions of small opacities of 1/0 or greater at a mean time since first silica exposure of 36.1 years. Of miners with cumulative silica exposures of 2 mg/m3-years or less, 20% had silicosis; of miners accumulating > 2 mg/m3-years, 63% had silicosis. Average silica exposure was also strongly associated with silicosis prevalence rates, with 13% silicoties among those with average exposure of 0.025–0.05 mg/m3, 34% among those with exposures of > 0.05–0.1 mg/m3, and 75% among those with average exposures > 0.1 mg/m3. Logistic regression models demonstrated that time since last silica exposure and either cumulative silica exposure or a combination of average silica exposure and duration of exposure predicted silicosis risk. Exposure-response relations were substantially higher using measured silica exposures than using estimated silica exposures based on measured dust exposures assuming a constant silica proportion of dust, consistent with less exposure misclassification. The risk of silicosis found in this study is higher than has been found in workforce studies having no follow-up of those leaving the mining industry and in studies without job title-specific silica measurements, but comparable to several recent studies of dust exposure-response relationships which suggest that a permissible exposure limit of 0.1 mg/m3 for silica does not protect against radiologic silicosis. © 1996 Wiley-Liss, Inc.  相似文献   

    14.
    15.
    In 1974, the National Institute for Occupational Safety and Health recommended a ban on the use of silica sand abrasives containing >1% silica due to the risk of silicosis. This gave rise to substitutes including coal slag. An Occupational Safety and Health Administration investigation in 2010 uncovered a case cluster of suspected pneumoconiosis in four former workers at a coal slag processing facility in Illinois, possibly attributable to occupational exposure to coal slag dust. This article presents the results from a National Institute for Occupational Safety and Health industrial hygiene survey at the same coal slag processing facility and a second facility. The industrial hygiene survey consisted of the collection of: (a) bulk samples of unprocessed coal slag, finished granule product, and settled dust for metals and silica; (b) full-shift area air samples for dust, metals, and crystalline silica; and (c) full-shift personal air samples for dust, metals, and crystalline silica.

    Bulk samples consisted mainly of iron, manganese, titanium, and vanadium. Some samples had detectable levels of arsenic, beryllium, cadmium, and cobalt. Unprocessed coal slags from Illinois and Kentucky contained 0.43–0.48% (4,300–4,800 mg/kg) silica. Full-shift area air samples identified elevated total dust levels in the screen (2–38 mg/m3) and bag house (21 mg/m3) areas. Full-shift area air samples identified beryllium, chromium, cobalt, copper, iron, nickel, manganese, and vanadium. Overall, personal air samples for total and respirable dust (0.1–6.6 mg/m3 total; and 0.1–0.4 mg/m3 respirable) were lower than area air samples. All full-shift personal air samples for metals and silica were below published occupational exposure limits. All bulk samples of finished product granules contained less than 1% silica, supporting the claim coal slag may present less risk for silicosis than silica sand. We note that the results presented here are solely from two coal slag processing facilities, and more in-depth air monitoring is needed to better characterize occupational exposure to coal slag dust, metals, and silica at similar facilities.  相似文献   


    16.
    The aim of this study is to determine exposure levels as well as compliance status on respirable dust and respirable crystalline silica (RCS)-quartz exposure among crusher operators at Malaysian quarries. The exposure level at each crushing process was compared. Monitoring was performed among 70 crusher operators at nine quarries. Eight hours long-term personal samples were collected according to the National Institute of Occupational Safety and Health (NIOSH) Manual Analytical Method (NMAM) 0600 for respirable dust and NMAM 7500 for respirable crystalline silica (RCS-quartz). A questionnaire on silica dust monitoring and control was also sent to all granite quarries in Malaysia. The results indicated that the mean percentage of RCS-quartz in silica dust was 23.7 %. The mean value for crusher operators’ exposure was 0.426 mg m?3 for respirable dust and 0.091 mg m?3 for RCS-quartz. Around 30.5 % of crusher operators were exposed to RCS-quartz levels above the permissible exposure limit (PEL) based on Malaysian’s Occupational Safety and Health Regulations 2000. Operators in charge of combined secondary and tertiary crusher plants were exposed to 0.116 mg m?3 of RCS-quartz, which was higher compared to those operating individual plants. Results on posted questionnaire indicate that Malaysian quarries are more preferred to perform respirable dust monitoring (37 %) instead of specific RCS-quartz monitoring (22.6 %). Low exposure to respirable dust may conceal the need to justify comprehensive crystalline silica dust monitoring and lead to underestimation of RCS-quartz exposure. A high percentage of non-compliance exposure on personal RCS-quartz exposure should establish the need for quarry management to focus on better implementation of dust control systems.  相似文献   

    17.
    The total dust concentration and the particle size distribution were determined around die sites of demolition associated with the Great Hanshin-Awaji Earthquake, which occurred on January 17, 1995. The total dust concentrations ranged from 0.20 to 0.23 mg/m3, being about 1.2 to 2.2 times that in die non-demolition area, and intermediate particles (2.1-11.0μm) made up a large proportion of the dust. The dust concentrations were not influenced by the weather on the day preceding measurement around the sites of demolition of concrete buildings, whereas the values decreased to about half around die sites of demolition of wooden buildings, nearly the same concentration in the control areas, when it had rained on the previous day. The dust concentrations increased compared with that in an average year but to The degree of die upper limit of die environmental standard (1 hr-value<0.20 mg/m3) . The dust due to the smoke of Mt. Sakurajima in the surrounding areas accounted for a higher proportion of large particles (<11.0>m) than in the earthquake-devastated area. The concentration of respirable dust (<;7.07>m) in a worker engaged in demolition was 4.0 mg/m3, being twice the recommended concentration (2 mg/m3) of the Japan Society for Occupational Health. It was thus considered that workers should use a respiratory protective device.  相似文献   

    18.
    OBJECTIVE—To use various exposure-response models to estimate the risk of mortality from lung cancer due to occupational exposure to respirable crystalline silica dust.
    METHODS—Data from a cohort mortality study of 2342 white male California diatomaceous earth mining and processing workers exposed to crystalline silica dust (mainly cristobalite) were reanalyzed with Poisson regression and Cox's proportional hazards models. Internal and external adjustments were used to control for potential confounding from the effects of time since first observation, calendar time, age, and Hispanic ethnicity. Cubic smoothing spline models were used to assess the fit of the models. Exposures were lagged by 10 years. Evaluations of the fit of the models were performed by comparing their deviances. Lifetime risks of lung cancer were estimated up to age 85 with an actuarial approach that accounted for competing causes of death.
    RESULTS—Exposure to respirable crystalline silica dust was a significant predictor (p<0.05) in nearly all of the models evaluated and the linear relative rate model with a 10 year exposure lag seemed to give the best fit in the Poisson regression analysis. For those who died of lung cancer the linear relative rate model predicted rate ratios for mortality from lung cancer of about 1.6 for the mean cumulative exposure to respirable silica compared with no exposure. The excess lifetime risk (to age 85) of mortality from lung cancer for white men exposed for 45 years and with a 10 year lag period at the current Occupational Safety and Health Administration (OSHA) standard of about 0.05 mg/m3 for respirable cristobalite dust is 19/1000 (95% confidence interval (95% CI) 5/1000 to 46/1000).
    CONCLUSIONS—There was a significant risk of mortality from lung cancer that increased with cumulative exposure to respirable crystalline silica dust. The predicted number of deaths from lung cancer suggests that current occupational health standards may not be adequately protecting workers from the risk of lung cancer.


    Keywords: crystalline silica; cristobalite; lung cancer  相似文献   

    19.

    Background

    About 12 million workers are involved in the production of basic grains in Central America. However, few studies in the region have examined the occupational factors associated with inhalable dust exposure.

    Objectives

    (i) To assess the exposure to inhalable dust in workers from rice, maize, and wheat storage facilities in Costa Rica; (ii) to examine the occupational factors associated with this exposure; and (iii) to measure concentrations of respirable and thoracic particles in different areas of the storage facilities.

    Methods

    We measured inhalable (<100 μm) dust concentrations in 176 personal samples collected from 136 workers of eight grain storage facilities in Costa Rica. We also measured respirable (<4 μm) and thoracic (<10 μm) dust particles in several areas of the storage facilities.

    Results

    Geometric mean (GM) and geometric standard deviation (GSD) inhalable dust concentrations were 2.0 mg/m3 and 7.8 (range = < 0.2–275.4 mg/m3). Personal inhalable dust concentrations were associated with job category [GM for category/GM for administrative staff and other workers (95% CI) = 4.4 (2.6, 7.2) for packing; 20.4 (12.3, 34.7) for dehulling; 109.6 (50.1, 234.4) for unloading in flat bed sheds; 24.0 (14.5, 39.8) for unloading in pits; and 31.6 (18.6, 52.5) for drying], and cleaning task [15.8 (95% CI: 10.0, 26.3) in workers who cleaned in addition to their regular tasks]. Higher area concentrations of thoracic dust particles were found in wheat (GM and GSD = 4.3 mg/m3 and 4.5) and maize (3.0 mg/m3 and 3.9) storage facilities, and in grain drying (2.3 mg/m3 and 3.1) and unloading (1.5 mg/m3 and 4.8) areas.

    Conclusions

    Operators of grain storage facilities showed elevated inhalable dust concentrations, mostly above international exposure limits. Better engineering and administrative controls are needed.  相似文献   

    20.
    Portovelo is one of the oldest gold mining towns in Ecuador. Artisanal gold mining still uses mercury in the process of gold recovery. In this study, mercury concentrations in the air of Portovelo were evaluated. High mercury levels in the ambient were found in El Pache sector, where most gold mining processing plants are located. These varied between 2,356.7 ± 1,807.6 and 3,699.5 ± 1,225.3 ng/m3 during the rainy and dry seasons, respectively. Lower levels were detected in the urban (central) area of Portovelo, with 214.6 ± 43.7 ng/m3 in the rainy season and 574.2 ± 72.8 ng/m3 in the dry season, exceeding the Agency for Toxic Substances and Disease Registry minimum risk level of 200 ng/m3. Average mercury concentrations in exhaled air from miners, measured before and after amalgam burning ranged between 179–1,352 and 2,007–3,389 ng/m3, respectively. These data suggest Portovelo air is polluted with mercury and humans are being dangerously exposed. Therefore, strong actions must be undertaken to protect human and environmental health, including changing gold recovery systems.  相似文献   

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