Glomus tumor of the stomach

A case of the stomach glomus tumour is described in a male of 67, with an asymptomatic clinical course. Results of the angiographic, computer-tomographic examination as well as morphological characteristics of the tumour are presented.     

气管血管球瘤一例

患者男,29岁。间断性咳嗽2年,症状加重伴气短2个月,于2003年12月25日入院。术前CT示：隆突上方,气管下段可见不规则形肿物。支气管镜检查：气管下段可见葡葡状肿物突向腔内。手术行气管节段切除,端端吻合术。     

Glomus tumor of lesser omentum--a case report

A case of glomus tumor of lesser omentum occurring in a 24 years old male is being reported for its rarity.     

Glomus tumor of the duodenum: a case report

We describe a rare case of glomus tumor of the duodenum. The tumor was detected in a 46-year-old man being investigated for episodes of gastrointestinal bleeding. The excised specimen showed a 2.3 x 1.5 x 1.5 cm gray-tan tumor involving the mucosa and the submucosa. The overlying mucosa was focally ulcerated. Histologically, the tumor had a solid pattern of sharply demarcated, round glomus cells with prominent pericytoma-like vessels of varying sizes. The neoplastic cells stained for vimentin, smooth muscle actin, and focally for synaptophysin. These histologic and immunohistochemical features are consistent with a diagnosis of glomus tumor of the duodenum.     

Glomus tumor of the trachea: a rare case report

A tracheal glomus tumor is extremely rare. There were approximately 18 reported cases before in China. Here we report a 48-year-old male with glomus tumor of the trachea. The computed tomography (CT) scan of the chest showed a nodulein the basalsegmentof right lower lobe, focal uplift in the left-posterior wall of the trachea, measured 1.5×1.2×1.0 cm. Microscopically, the tumor tissue was rich with vessels, shaped flake-nest, and the tumor consisted of a sheet of uniform cells surrounding the vascular spaces. Immumohistochemical staining were positive for SMA, vimentin, collagen IV, CD34, the Ki-67 proliferation activity was low (<1%), and were negative for Syn, CgA, S-100, AE1/AE3 and EMA. PSA staining showing clear cell borders. With a review of the literature, the clinical, pathological characteristics and treatment modalities of this rare tumor are discussed.     

Glomus tumor of the stomach. Histologic and ultrastructural features

A glomus tumor of the stomach was found in a 79-year-old white man who had episodes of upper gastrointestinal bleeding. Clinically, this uncommon gastric tumor mimics most of the benign and malignant lesions of the stomach. The most important aspect of this tumor, therefore, is its histologic identification and differentiation from the more common gastric lesions, most especially malignant tumors. This is of paramount importance because the glomus tumor is essentially benign and does not warrant a radical surgical procedure. The histologic and ultrastructural features of this particular gastric neoplasm are presented and discussed.     

颈静脉球瘤1例及副神经节瘤文献复习

目的探讨颈静脉球瘤的临床病理特征和副神经节瘤的生物学行为。方法对1例颈静脉球瘤进行组织学观察和免疫组化标记,同时复习相关文献。结果颈静脉球瘤的组织学改变类似于其他部位的副神经节瘤,免疫组化标记:瘤细胞Syn、CgA和NSE均阳性,EMA、CK、HMB45、CD34和CD99均阴性。结论颈静脉球瘤是一种起源于副神经节的少见肿瘤,呈侵袭性生长,有低度恶性的生物学行为。根据肿瘤的组织学特征,结合CT或MR I影像学资料和免疫组化标记可以作出诊断。     

Glomus tumor and knee pain: A report of four cases

We present four cases of glomus tumors presenting as knee pain. All cases were treated by surgical excision of the tumor. All patients made an immediate recovery with return to full normal function.The presentation of this is unique in that the patient has exquisite pain and tenderness when the area affected is palpated. Occasionally, local infiltration or an ischaemia test can assist with diagnosis. To our knowledge, this is the largest case series in the literature.     

Glomus tumor of the trachea. Immunohistochemical and electron microscopic studies

Glomus tumor of the trachea which developed in a 51-year-old man was reported. He experienced frequent episodes of respiratory infections and hemoptosis for 9 months. Bronchofiberscopic study demonstrated a polypoid tumor in the upper trachea. Local resection of the tumor was performed and it arised from the membranous portion of the third and fourth tracheal rings. Histologically, the tumor was composed of medium-sized rounded cells, resembling carcinoid tumor. Desmin and myosin immunoreactivities were found in most of the tumor cells. Electron microscopic examination showed that the tumor cells contained fine filaments with focal density, numerous pinocytotic vesicles along the plasma membrane and abundant mitochondria. The patient is well without evidences of tumor recurrence 2 years after the resection. This is the fourth report of the tracheal glomus tumor with definitive evidences of smooth muscle differentiation of the tumor cells.     

Ultrastructural study of hemangiomas. 5. Glomus tumor (Masson)

The fine structure of four cases of glomus tumor was described. All of the cases showed a solid type, and the glomus cells were shown to be typical or modified smooth muscle cells. Our conclusion is that the glomus cells are not derived from pericytes, but from smooth muscle cells of vascular part of the glomus, and are thought to be a specialized smooth muscle cell tumor.     

Glomus tumor of the mesentery with atypical features: a case report

Glomus tumors usually occur in the acral soft tissue and rarely in visceral locations, such as the stomach, intestines, mediastinum, lung, pancreas, bladder, and vagina. The authors present a 74-year-old woman with an exceptionally large glomus tumor of the mesentrium with malignant features. Previously reported cases of intraabdominal glomus tumor in the abdominal cavity exhibited benign behavior and few cases with metastatic disease. Criteria for malignancy in acral glomus tumors, such as unusually large size, infiltrative growth, necrosis, nuclear atypia, and mitotic activity, seem not to translate to abdominal glomus tumors. As very few intraabdominal glomus are described, the malignant potential of these tumors stays uncertain for longer period.     

Glomus tumor of the coccyx. A curable cause of coccygodynia.

A 30-year-old woman presented with recurrent severe coccygodynia. She underwent exploration for a possible pilonidal sinus and was found to have a precoccygeal glomus tumor that also involved bony trabeculae of the coccyx. To our knowledge, a glomus tumor involving the coccygeal bone has not been previously documented. In view of the relief of this patient's pain following the surgical excision of coccyx and tumor, a causal role is suggested.     

Glomus tumor of the stomach: cytologic diagnosis by endoscopic ultrasound-guided fine-needle aspiration

The glomus tumor is usually a benign solitary neoplasm that arises from modified smooth muscle cells of the glomus body, a type of neuromyoarterial receptor that plays a role in the regulation of arterial blood flow. We report a case of gastric glomus tumor diagnosed by endoscopic ultrasound-guided fine-needle aspiration. Smears exhibited groups of cohesive, uniform, small, round to polygonal cells with scant cytoplasm, indistinct cell borders, and round, hyperchromatic nuclei with homogeneous chromatin. The cell block contained fragments of cells with similar morphologic features and immunohistochemical staining exhibited positivity for smooth muscle actin and vimentin. The diagnosis was confirmed by the surgically resected specimen. Ultrastructural examination revealed prominent pinocytotic vesicles lining the plasmalemma. In this report, we discuss the differential diagnosis of gastric glomus tumor and compare the cytologic features of this case with two others reported in the literature.     

Glomus tumor beneath the plica synovialis in the knee: a case report

Glomus tumors are rare benign tumors distinguished clinically by their small size and ability to cause extreme pain. These lesions are usually found beneath the fingernails. Atypical locations of the tumor are difficult to diagnose, especially when the lesion is situated in a deep anatomic structure. We describe a 33-year-old man with glomus tumor beneath the plica synovialis in the knee. He had experienced right knee pain for 10 years which increased with movements of the knee. There was a point of tenderness on palpation at the lateral aspect of the knee. CT scan with arthrography showed a small mass on the lateral femoral condyle in the joint space. It was seen retrospectively in MRI. Arthroscopy demonstrated the soft tissue mass beneath the plica synovialis. We made a separate incision and removed it completely. An immediate disappearance of the pain was observed after surgery. Histology was the glomus tumor of the vascular type. The tumor seemed to be stimulated by the plica synovitis or the lateral joint capsule and it caused pain on motion similar to meniscal tear. There has been no recurrence for 3 years after surgery.