Body fat distribution and job stress in Mexican-American men of the hispanic health and nutrition examination survey

A positive relationship between psychosocial stress and central body fat distribution has been hypothesized. To test this hypothesis, two indices derived from principal components analysis of four skinfold measurements were studied in relation to imputed job stress characteristics (decision latitude, skill discretion, decision authority, and psychological demands) in Mexican-American men of the U.S. Hispanic Health and Nutrition Examination Survey (HHANES). The two indices were fatness and central body fat distribution. Fatness was not significantly associated with any of the job stress characteristics before controlling for education. Once education was included in the equations, however, the relationship between fatness and two of the four job stress variables (decision authority and psychological demands) became statistically significant. Thus, for a given level of education, increasing job stress was associated with increasing fatness. Three of the four job stress characteristics were significantly associated with central body fat distribution before controlling for education. However, after education was entered into the regression equations as a proxy for social class, the relationships between central body fat distribution and the job stress variables were no longer significant. It thus appears that aspects of social class other than job stress are of equal or greater importance in predicting body fat distribution. © 1992 Wiley-Liss, Inc.     

Body fat distribution: Associations with socioeconomic status in the Hispanic health and nutrition examination survey

Three indices derived from principal components analysis of four skinfold measurements were studied in relation to socioeconomic status (SES; income and education) in men and women of the U.S. Hispanic Health and Nutrition Examination Survey (HHANES). The three indices were fatness (PC1), central body fat distribution (PC2), and “centralized obesity” (PC1 + PC2). The well-known inverse relation of fatness (PC1) with SES was demonstrated in women. This relationship tended to be positive in men, but not consistently so within the three Hispanic groups (Puerto Rican, Cuban, Mexican-Americans) studied. A negative association of central body fat distribution (PC2) was also evident in both sexes and in all three groups except in Puerto Rican men, in whom the relationship was no longer significant after age adjustments. The third index combined information on both fatness level and central distribution. It was strongly related to SES in women but not in men.     

Prevalence of overweight and cardiovascular risk factors in rural and urban children from Central Asia: the Kazakhstan health and nutrition examination survey.

Kazakhstan is undergoing a rapid modernization process, which carries the risk of an epidemic of obesity and cardiovascular disease. We enrolled a sample of about 50 children for every combination of gender, environment (urban vs. rural), ethnic group (Kazakh vs. Russian), and age group from 7 to 18 years, for a total of 4,808 children. Anthropometry and blood pressure were measured on all children while fasting blood cholesterol and glucose were measured only in 2,616 children aged > or =12 years. The prevalence of overweight and risk of overweight ranged from 2.8 (rural male Kazakhs) to 9.1% (urban male Russians). The prevalence of prehypertension and hypertension ranged from 8.3 (urban females) to 15.9% (rural females); that of hypercholesterolemia from 11.5 (male rural Russians) to 26.5% (female rural Kazakhs); and the overall prevalence of impaired fasting glucose was 0.1%. We conclude that overweight and cardiovascular risk factors are less prevalent in children living in Kazakhstan than in those living in Western countries. However, these figures are not negligible and suggest that preventive measures are needed to contain the epidemic of overweight and cardiovascular disease that will most likely accompany the modernization of Kazakhstan in the next years.     

Parity,adiposity, and body fat distribution among Hispanic women

The relationship between parity and body fat distribution was investigated in a sample of 1,590 Mexican American, 411 Cuban American, and 657 Puerto Rican women, aged 20–74 years. Participants were interviewed and examined as part of the Hispanic Health and Nutrition Examination Survey, a cross-sectional study of a representative sample of Hispanic populations residing in the United States. In each ethnic group, there was an increase with greater parity in overall body fat (body mass index [BMI], or triceps plus subscapular skinfolds), central vs. peripheral skinfold thicknesses (subscapular/triceps ratio), and upper vs. lower body skinfold thicknesses (subscapular/calf ratio). These positive associations remained after adjusting for age, income, marital status, smoking, menopausal status, and education. They were statistically significant only in the Mexican American group. After controlling for the BMI, the association between parity and the subscapular/ calf ratio remained significant in Mexican Americans, suggesting a relationship between parity and upper body fat distribution independent of body size. © 1995 Wiley-Liss, Inc.     

Fatness and fat pattering in 12–17-year-old youth from the Chandigarh zone of Northwest India

Fatness and fat patterning were studied in a sample of 502 youth, 12–17 years of age, of high and low socioeconomic status (SES) from the Chandigarh Zone of northwest India. Fatness estimates were based on six skinfolds, while fat patterning was analyzed through the centripetal fat and waist/hip ratios, and through principal components of skinfolds. In all analyses, fat patterns were adjusted for general body fatness. Upper SES subjects were larger and fatter than lower SES subjects of the same age and sex. As expected, females displayed higher fatness levels than males, a more peripheral distribution of body fat, and lower body patterning of trunk fat. Lower SES was associated with a centripetal, rather than a peripheral, fat pattern. After correction for amount of fat, there were no differences between SES groups in the waist/hip ratio, within-sex. Compared to U.S. youth of a similar age range, Indian subjects displayed higher BMI-adjusted centripetal fat and waist/hip ratios. Lower SES was associated with reduced body fatness along with a centralized pattern of fat deposition, which could reflect a greater mobilization of peripheral fat to meet the metabolic demands of growth. While there was some suggestion of an ethnic effect in the two ratios, this could not be demonstrated with confidence.     

Obesity and upper body fat distribution in Mexican American children from families with a diabetic proband

Upper and centralized body fat distribution is associated with non-insulin dependent diabetes mellitus (NIDDM). Few studies have focused on anthropometric characteristics of preadults from families in which there is a diabetic (NIDDM) proband. This study explores the prevalence of upper and centralized body fatness in Mexican American children from the Diabetes Alert study (1981–1983) in Starr County, Texas. Anthropometric data on 165 males and 224 females 9–19 years include measures of adiposity such as skinfold thicknesses and the body mass index (BMI), a measure of overweight. They show rates of obesity two to three times that of White children of comparable age and sex from National Health Surveys. In comparison with U.S. White subjects, Mexican American adults are shorter, have more adiposity and arm muscle mass and have sitting heights and body breadths at the mean of these dimensions for the U.S. population. Children from Diabetes Alert families show only marginal excess of severe obesity (> 95th percentile of BMI) when compared to the general population of children surveyed in Starr County schools. Girls from these families, but not boys, have excess fatness in the BMI compared to Mexican American children from the Hispanic Health and Nutrition Examination Survey (HHANES); suprailiac skinfold thicknesses are also greater in children of the Diabetes Alert study than in HHANES children. From 1972 through 1982, Mexican American children in South Texas showed an increase in average stature, weight, and the BMI. These data together suggest that excessive obesity exists and may be increasing in children in populations at risk for NIDDM. The prevention of NIDDM in the Mexican American population may be more effective if educational and promotional interventions include the school aged population. © 1993 Wiley-Liss, Inc.     

<Emphasis Type="Italic">CRP</Emphasis> polymorphisms and chronic kidney disease in the third national health and nutrition examination survey

Background

CRP gene polymorphisms are associated with serum C-reactive protein concentrations and may play a role in chronic kidney disease (CKD) progression. We recently reported an association between the gene variant rs2808630 and CKD progression in African Americans with hypertensive kidney disease. This association has not been studied in other ethnic groups.

Methods

We used data from 5955 participants from Phase 2 of The Third National Health and Nutrition Examination Survey (1991-1994) to study the association between CRP polymorphisms and CKD prevalence in a population-based sample. The primary outcome was CKD defined as estimated glomerular filtration rate (eGFR) <60 ml/min or the presence of albuminuria. Secondary outcomes were the presence of albuminuria (any degree) and continuous eGFR. Six single nucleotide polymorphisms (SNPs) from the CRP gene, rs2808630, rs1205, rs3093066, rs1417938, rs3093058, and rs1800947, were evaluated.

Results

CRP rs2808630 AG compared to the referent AA genotype was associated with CKD in non-Hispanic blacks (n = 1649, 293 of whom had CKD) with an adjusted odds ratio (OR) of 3.09 (95% CI 1.65-5.8; p = 0.001). For the secondary outcomes, rs2808630 AG compared to the referent AA genotype was associated with albuminuria with an adjusted OR of 3.07 (95% CI 1.59-5.94; p = 0.002), however not with eGFR. There was no association between the SNPs and CKD, albuminuria or eGFR in non-Hispanic whites or Mexicans Americans.

Conclusions

In this cross-sectional study, the 3' flanking CRP gene variant rs2808630 was associated with CKD, mainly through its association with albuminuria in the non-Hispanic blacks. Despite not finding an association with eGFR, our results support our previous study demonstrating an association between CRP gene variant rs2808630 and CKD progression in a longitudinal cohort of African American with hypertensive kidney disease.

     

Fatness and overweight in women and children from riverine Amerindian communities of the Beni River (Bolivian Amazon).

Obesity is a worldwide public health problem impacting not only industrialized nations but also developing countries. The main objective of this paper was to analyze risk factors for overweight among Amerindian children and their mothers. Data were collected in 15 Amerindian riverside communities from the Beni River (Bolivia). The total sample was of 195 mothers and 452 children, 0-15 years of age. Information about family activity and dietary patterns was collected, and a clinical examination was performed. Stool samples were collected in children for parasitological screening. Anthropometric measurements, including weight, height, arm circumference, and four skinfolds, were taken. A bioelectrical impedance analysis was performed in mothers. In total, 12.2% (95% confidence interval (CI(95%)) 9.1-15.9%) of the children were considered overweight; less than 1% were overtly obese International Obesity Task Force (IOTF) criteria. Among their mothers, 35.3% (CI(95%), 28.7-42.5%) were overweight (BMI (weight/height (2)) >25 kg/m(2)), and 5% (CI(95%), 2.5-5.1%) were obese (BMI >30 kg/m(2)). BMI was moderately related to anthropometric indices of body composition in children, but was highly correlated with fatness in mothers. The risk of overweight was not associated with environmental factors in children. In mothers, there was a significant relationship between BMI, health status, and dietary diversity score. There was a moderate association in boys between fatness and the BMI of their mothers (R(2) = 0.12, P < 0.001), but not in girls. These findings suggest a trend toward accumulation of fat related to possible changes at the economic and agricultural levels, even in remote rural areas.     

Weight,stature, and body mass index data for Mexican Americans from the third national health and nutrition examination survey (NHANES III, 1988–1994)

Selected age- and sex-specific percentiles are presented for 4,054 Mexican American children ages 1–18 years who were included in the third National Health and Nutrition Examination Survey (NHANES III, 1988–1994). These percentile values are compared with corresponding percentiles for Mexican Americans from the Hispanic Health and Nutrition Examination Survey (HHANES, 1982–1984). In each sex, the weight and weight/stature² percentiles from NHANES III were significantly larger than those from HHANES. For weight, the NHANES III values tended to be clearly larger after 11 years in males and females, and they were larger for weight/stature² at the 50th and 90th percentiles in each sex after 6 years. For stature, the NHANES III values were significantly larger at the 90th percentile among females, but the differences were not significant for any other percentiles among females or males. In comparison with non-Hispanic White children, Mexican American children tend to be shorter and heavier, especially after the preschool period. The similarity of the findings for stature from NHANES III and HHANES indicates that the shorter statures of Mexican Americans are not cohort-specific. The tendency to larger values for weight/stature² in Mexican Americans has important public heath implications since this ratio tends to track after early childhood, and high ratios in adulthood constitute an important risk factor for common diseases such as diabetes mellitus and coronary heart disease. Am. J. Hum. Biol. 11:673–686, 1999. © 1999 Wiley-Liss, Inc.     

Identifying somatization disorder in a population-based health examination survey: psychosocial burden and gender differences

Despite its enormous medical burden, little is known about the epidemiology of somatization in the community. The present study screened a representative population-based survey of 7,466 subjects in the age range of 25 to 69 years for the occurrence of somatization. A total of 137 (1.84%) individuals experienced six or more symptoms from at least two different body sites without an identifiable organic cause. These patients exhibited a lower quality of life (P < or = 0.0001) and suffered from higher levels of emotional stress (P < or = 0.0001) than their counterparts in the healthy subsample (n=906). Somatization was not associated with a medical diagnosis, but disability days, the use of medical services, and the level of medication was higher in the somatization disorder group (P < or = 0.004). The somatization risk was only 1.6-fold higher for women in comparison to men but escalated for women rapidly to an approximately 4-fold risk when being female was combined with low social class and high emotional distress. Against expectation, the somatization risk for men also mounted 3-fold under the identical risk constellation.