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1.
心肌声学造影及其临床应用四川省人民医院李春梅,综述尹立雪审校1984年Demaria等首先应用心肌声学造影(MCE)直接使心肌灌注显像。同年Goldman等首次在手术室内用MCE检测冠脉搭桥术患者的心肌灌注。80年代末、90年代初MCE逐步得以完善。...  相似文献   

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心肌声学造影的应用及进展   总被引:1,自引:0,他引:1  
心肌声学造影的应用及进展王浩刘延玲刘汉英二维超声心动图的心肌声学造影(MCE),即向血管内注入含有微气泡的造影剂,当微气泡经过微血管到达心肌时,由于微气泡对超声的散射作用,使心肌组织回声增强,同步的超声检查即可获得清晰的心肌组织影像[1]。因经静脉注...  相似文献   

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随着超声增强剂(UEA)的改良、超声成像技术的完善,心肌声学造影已成为临床无创、安全、有效、实时、价廉的新技术。该文主要介绍心肌声学造影在心脏病诊断治疗中的应用。  相似文献   

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心肌声学造影在冠心病中的应用   总被引:1,自引:0,他引:1  
心肌声学造影(MCE)是指注射含有微气泡的声学造影剂后,应用二维或多普勒超声技术观察心肌灌注的诊断技术.近年来,随着MCE基础理论、超声造影剂与显像技术的迅速发展,MCE已从实验室研究走向临床应用,有望成为临床上实时、安全、准确评价心肌灌注的诊断技术.本文就MCE在冠心病中的应用研究现状做一综述.  相似文献   

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经皮冠状动脉造影、核素心肌显像等技术的出现使我们在心肌缺血和存活诊断方面取得了长足进展 ,但这些手段仍有一定缺陷 ,经皮冠状动脉造影可直接观察冠状动脉的狭窄的部位及严重程度 ,但仅能观察直径 >10 0 μm的血管且为有创检查 ,有一定风险。核素检查费用昂贵且有放射辐射  相似文献   

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罗支农 《心功能杂志》1992,4(3):F002-F002,191
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心肌造影超声心动图 (Myocardial ContrastEchocardiography,MCE)在评价心肌血流灌注中的运用成为一项十分热门的研究课题。MCE是指将含有微气泡的造影剂直接经冠状动脉或外周静脉注入 ,当微泡通过心肌微血管床时 ,应用二维或多普勒超声技术增强含血心肌的超声心动图显像 ,观察心肌血流灌注、冠脉血流储备。本文就近年来心肌声学造影在冠心病诊断方面的研究作一综述。1 声学造影剂的研究声学造影剂是 MCE的决定性因素之一。早年造影剂所产生的微泡直径大、不均匀、易破裂 ,无法通过肺循环进入左心室。故这项技术主要用于右心显影 ,认…  相似文献   

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心肌声学造影是诊断微循环水平心肌灌注的新技术。近年来无创性的心肌声学造影取得了突破性进展,已从实验室走向临床应用,现将心肌声学造影在冠心病方面应用的研究进展做一综述。  相似文献   

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目的:通过实时心肌声学造影(MCE),检测有心绞痛症状而冠状动脉造影(CAG)正常的高血压患者心肌微血管功能. 方法:入选有心绞痛症状而CAG正常的患者12例(高血压组),心绞痛症状不典型而CAG正常的非高血压患者8例(对照组),采用声学造影剂声诺维进行实时MCE检查,分别测定静息状态和腺苷负荷后造影剂微泡达到峰值的平台期强度(A),再充盈平均速度(β)及A·β,并测定A比值、β比值和冠状动脉血流储备(CFR)值.结果:高血压组静息时反映局部心肌血容量的A值、反映局部心肌血流量的A·β值与对照组差异无统计学意义(P>0.05),而反应局部心肌血流速度的β值小于对照组(P<0.05),反应心肌血容量储备的A比值、反应心肌血流速度储备的β比值较对照组低(P<0.05),高血压组CFR低于对照组(P<0.01).结论:有心绞痛症状而CAG正常的高血压患者心肌缺血与心肌微血管密度下降、CFR减退有关,实时MCE可定量检测心肌微血管功能.  相似文献   

10.
王红  黄岚 《心脏杂志》2006,18(5):595-597
超声心肌声学造影为一种诊断心肌组织水平灌注的新型超声技术,可从微循环完整性的角度评价存活心肌。存活心肌的识别对冠状动脉粥样硬化性心脏病患者选择积极、合理的治疗方案、评估疗效及预后有重要临床价值。本文就该技术对存活心肌的评价及临床意义作一综述。  相似文献   

11.
Myocardial contrast echocardiography (MCE) enables direct assessment of the degree and adequacy of microvascular perfusion as well as the presence of wall motion abnormalities. MCE has the following benefits in patients with acute myocardial infarction (MI): 1) rapid and definite diagnosis of acute MI; 2) identification of patients who may benefit from prompt reperfusion therapy; 3) assessment of the efficacy of mechanical or pharmacologic intervention for an open infarct-related artery; 4) estimation of MI size early after reperfusion and residual myocardial viability; 5) identification of being at high risk for post-MI complications and left ventricular remodeling; and 6) assessment of myocardial viability and ischemia prior to hospital discharge. Therefore, MCE is an ideal tool for correct triaging of patients to revascularization and has both prognostic and therapeutic implications in patients with acute MI.  相似文献   

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心肌造影负荷超声心动图将心肌造影与负荷超声相结合,通过检测心肌微循环完整性和心肌血流灌注情况,为临床上冠心病的评价提供了一种简便、可靠、准确的新方法。现就心肌造影负荷超声心动图研究与应用现状作一综述。  相似文献   

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We evaluated the clinical applicability of a system for three-dimensional (3-D) display of a perfusion map following myocardial contrast echocardiography (MCE). The system was used in 12 patients (9 males and 3 females, mean age 52 ± 10 years) undergoing interventional treatment of chronic total coronary occlusion. In each patient three standard apical views were acquired at baseline with sonicated IopamidolR injections into the left coronary artery (LCA) and into the right coronary artery (RCA). Following successful recanalization of the occluded artery MCE was repeated. The patients tolerated the procedure well. Acquisition of three standard apical views provided sufficient information for the reconstruction of 3-D perfusion maps containing the 16 standard left ventricular (LV) segments. Side-by-side display of the perfusion maps obtained following LCA and RCA echocontrast injections allowed us to classify the myocardial segments (192) into three groups: (1) those supplied by one major artery (124); (2) those supplied by collaterals from contralateral or both major arteries (58); and (3) segments supplied by none of the major arteries (10). Decreased opacification was observed in 50 segments of group 2. Following successful intervention we were able to visualize the redistribution of blood flow delivered to the LV myocardium by each major coronary artery in 3-D format. We conclude that this 3-D approach, which can easily be performed with currently available ultrasound equipment, allows an estimate of the contribution of each major coronary artery to LV perfusion before and after coronary angioplasty.  相似文献   

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