共查询到20条相似文献,搜索用时 46 毫秒
1.
2.
目的 为提高我国胰岛素质量标准提供参考.方法 概括了我国胰岛素发展状况;依据《中国药典》1953年版~2010年版,对我国胰岛素质量标准及其制剂的发展进程进行综述,并指出存在的问题.结果与结论 从《中国药典》1953年版收载胰岛素至今,我国胰岛素质量不断提高,标准不断完善,我国第三代胰岛素正快速发展,逐步缩短与国外差距,但目前《中国药典》收载的胰岛素品种和制剂还很少,《中国药典》2015年版将面临新的挑战. 相似文献
3.
胰岛素及其制剂质量标准的比较 总被引:1,自引:0,他引:1
此文综述了建国以来胰岛素及其制剂质量标准的研究进展 ,并对现行版本《中国药典》与《美国药典》ⅩⅩⅦ版标准进行比较 ,以期找出差距 ,促进国内胰岛素产品质量的提高及剂型的开发。 相似文献
4.
5.
6.
7.
28什么是胰岛素类似物从最初的动物胰岛素到重组DNA技术制备的人胰岛素,都不能真正模拟人24 h胰岛素的分泌。胰岛素类似物的出现试图提供人体胰岛素的持续性基础分泌和刺激性增高分泌,胰岛素类似物都是改变了人胰岛素的氨基酸顺序及其理化性质而使其起 相似文献
8.
黄哲苏 《中国生化药物杂志》1998,19(6):399-400
对1995年版《中国药典》、23版美国药典、1993年版英国药典、12版日本药局方中胰岛素及其制剂的品种、主要质量标准和检验方法做一介绍。 相似文献
9.
10.
由于市场低于胰岛素类似物和凝血因子需求增加。诺和诺德制药公司2004年业绩比较好。胰岛素类似物销售增长77%,达到45亿丹麦克朗(9.49亿美元),其中以北美增长最快。胰岛素类似物销售占公司胰岛素产品销售的24%。公司的长效胰岛素类似物产品Levemir(胰岛素detemir)在欧洲的销售占整个欧洲长效胰岛素类似物市场的9%。 相似文献
11.
12.
The prevention of histamine-induced gastric and duodenal ulceration in the guinea-pig has been examined using a series of undegraded and degraded carrageenans. Undegraded carrageenans were active at lower doses than degraded carrageenans. The high viscosity of the undegraded carrageenans in solution prevented their use in larger doses. Degradation of carrageenan without serious loss of sulphate, gives a product which allows the dose to be increased to an extent that its effect more than offsets the slight loss in activity caused by the degradation. No single feature of carrageenan structure can be related to anti-ulcer activity although degradation, and hence reduction of molecular size, generally reduces activity. Sulphate contents over 30% have little apparent effect on activity; κ-carrageenans were not consistently different in anti-ulcer activity from Λ-carrageenans. This contrasts with the antipeptic activity of carrageenans where κ-carrageenans are less active than their Λ-counter-parts. As with antipeptic activity, the degree of anti-ulcer activity is probably determined by a combination of structural features which includes molecular size and polyanionic properties. 相似文献
13.
14.
15.
Larks and owls and health, wealth, and wisdom 总被引:1,自引:0,他引:1
16.
17.
18.
《Journal of addictive diseases》2013,32(3):73-87
Depression and anxiety frequently coexist in patients with substance use disorders. This clinically-oriented article examiens the relationship between these conditions and emphasizes data showing that substances of abuse can cause signs and symptoms of both depression and anxiety. These substance-related syndromes appear to have a different course and prognosis than uncomplicated, independent anxiety and major depressive disorders, and clinicians should consider the role of alcohol and other drugs in all patients presenting with these complaints. The authors will also outline an approach for diagnosing and managing patients with the combination of a substance use and depressive or anxiety disorder. 相似文献
19.
20.
Z J Witczak 《IDrugs : the investigational drugs journal》1998,1(1):30-31
The American Chemical Society Symposium "Glucosidase and fucosidase inhibitors" took place on 1 April 1998 and was organized by Professors Zbigniew J Witczak (UConn, School of Pharmacy, CT, USA), Kuniaki Tatsuta (Waseda University, Tokyo, Japan) and Waldemar Priebe, MD (Anderson Cancer Center, University of Texas, USA). Professor Witczak provided introductory remarks including the status of existing glucosidase inhibitors, and chaired the morning session, which consisted of six lectures. The symposium was well received, and was particularly attractive for those interested in networking, as attendance was about sixty. In addition, some participants and attendees presented posters on the subject during the regular poster session organized by the Division of Carbohydrate Chemistry. 相似文献