Evaluation of stroke management in an Irish university teaching hospital: the Royal College of Physicians stroke audit package

Background  

There are few data regarding the standard of stroke care in Ireland.     

Increased occurrence of cardiovascular events and comorbidities in a general rheumatology cohort

Background  

To identify cardiovascular and other comorbidities in a general rheumatology cohort.     

Prevalence and aetiology of leg ulcers in Ireland

Background  

The prevalence of leg ulcer disease in Ireland has been poorly documented.     

Predictors of first hip fracture and mortality post fracture in older women

Background  

Hip fracture causes significant morbidity and mortality in older women.     

Readability level of patient information leaflets for older people

Background  

Limited literacy is associated with a nearly twofold increase in mortality in older patients.     

Ease of access is a principal factor in the frequency of paracetamol overdose

Background  

In Ireland, 30% of non-fatal overdoses involve paracetamol.     

Small bowel volvulus secondary to a mesenteric lipoma; a case report and review of the literature

Background  

Small bowel volvulus is rare in adults and often has a precipitating factor.     

Hypertension in Ireland: public awareness and doctors choice of therapy

Background  

Hypertension is the commonest medical condition in Ireland.     

Prevalence of anaemia in patients with Diabetes Mellitus

Background  

Anaemia is an increasingly recognised entity in patients with diabetes mellitus.     

Schizophrenia in general practice: a national survey of general practitioners in Ireland

Background  

Chronic schizophrenia is challenging to manage in primary care.     

Effect of dachengqi granules on level of endotoxin in enterogenous endotoxemia in rats

Objective  

To study the effect of Dachengqi Granule (DCQG) on endotoxin level in rats of enterogenous endotoxemia.     

An evaluation of the range and availability of intensive smoking cessation services in Ireland

Background  

A review of smoking cessation (SC) services in Ireland is a necessary step in improving service planning and provision.     

Initial experiences with isolated limb perfusion for unresectable melanoma of the limb

Aims  

Our initial results with isolated limb perfusion (ILP) using melphalan ± TNF alpha in patients with unresectable melanoma of the limb were analyzed.     

FDG-PET scanning in the management of cancer of the oesophagus and oesophagogastric junction: Early experience with 100 consecutive cases

Background  

The aim was to evaluate the impact of FDG-PET scan on tumour staging and management decisions in oesophageal cancer.     

Feature representation in the biclustering of symptom-herb relationship in Chinese medicine

Objective  

To find an appropriate feature representation in the biclustering of symptom-herb relationship in Chinese medicine (CM).     

Prevalence of obstructive airflow limitation in Irish collegiate athletes

Background  

Asthma prevalence in athletes is variable, depending on the sport and training conditions.     

Perceived efficacy and risks of infection following intra-articular injections: a survey of orthopaedic surgeons

Background  

Efficacy of intra-articular injections is controversial and published studies on efficacy and risks are few.     

Clinical study on the treatment of gastroesophageal reflux by acupuncture

##正##Objective:To explore the clinical efficacy and safety of acupuncture in treating gastroesophageal reflux(GER).Methods:Sixty patients with confirmed diagnosis of GER were randomly assigned to two groups.The 30 patients in the treatment group were treated with acupuncture at acupoints Zhongwan(CV 12),bilateral Zusanli(ST36),Sanyinjiao(SP6),and Neiguan(PC6),once a day,for 1 week as a therapeutic course,with interval of 2-3 days between courses;the 30 patients in the control group were administered orally with omeprazole 20 mg twice a day and 20 mg mosapride thrice a day.The treatment in both group lasted 6 weeks.Patients' symptoms and times of reflux attacking were recorded,the 24-h intraesophageal acid/bile reflux were monitored,and the endoscopic feature of esophageal mucous membrane was graded and scored at three time points,i.e.,pre-treatment(T0),immediately after ending the treatment course(T1)and 4 weeks after it(T2).Besides,the adverse reactions were also observed.Results:Compared with those detected at T0, 24-h intraesophageal pH and bile reflux,endoscopic grading score and symptom score were all decreased significantly at T1 in both groups similarly(P0.01),showing insignificant difference between groups(P0.05). These indices were reversed at T2 to high level in the control group(P0.05),but the reversion did not occur in the treatment group(P0.05).No serious adverse reaction was found during the therapeutic period.Conclusion: Acupuncture can effectively inhibit the intraesophageal acid and bile reflux in GER patients to alleviate patients' symptoms with good safety and is well accepted by patients.     

The effect of the anaesthetic agent isoflurane on the rate of neutrophil apoptosisin vitro

Background  

Volatile anaesthetic agents influence neutrophil function, and potentially, the inflammatory response to surgery.