同期双侧人工全髋关节置换术后下肢深静脉血栓的预防及护理

目的:对同期双侧人工全髋关节置换术后下肢深静脉血栓的预防、护理方式进行分析。方法:抽选我院2014年1月到2016年4月间20例换双髋的患者,对所有患者的情况进行回顾性分析调查,调查患者深静脉血栓发生率以及患者护理方式。结果:20例患者有1例下肢深静脉血栓病例发生,发生率为5.0%。患者护理后生活质量评分为(93.7±20.1)分,明显高于患者护理前,比较存在明显差异,P0.05。结论:良好的预防、护理干预措施能够降低同期双侧人工全髋关节置换术后下肢深静脉发生率,提升患者生活质量。     

针对性护理预防人工髋关节置换术后下肢深静脉血栓的效果

目的探讨针对性护理预防人工髋关节置换术后下肢深静脉血栓的效果。方法 80例人工髋关节置换术患者随机法分为两组,对照组给予常规护理,实验组实施针对性护理。比较两组满意度、下肢深静脉血栓发生率,并比较护理前后两组患者的不良情绪。结果实验组满意度高于对照组,下肢深静脉血栓发生率高于对照组,护理后实验组不良情绪评分低于对照组(P0.05)。结论人工髋关节置换术患者实施针对性护理效果确切,可减少下肢深静脉血栓发生率,提高满意度,减轻患者的不良情绪。     

人工关节置换术后下肢深静脉血栓形成的预防及护理

目的 探讨关节置换术后下肢深静脉血栓形成的预防及护理方法.方法 回顾分析2008年1月～2010年1月我院收治的80例行人工髋关节、膝关节置换术患者的临床资料.针对下肢深静脉血栓形成的高危因素,采取相应的综合护理措施.结果 本组80例患者中,有6例发生下肢深静脉血栓,发生率为7.5%.结论 严密的病情观察及精心的护理是预防下肢深静脉血栓形成的关键.     

人工髋关节置换术后下肢深静脉血栓的预防及护理

目的 探讨人工髋关节置换术后下肢深静脉血栓的预防及护理效果.方法 对52例人工髋关节置换术患者的临床资料进行回顾性分析,观察患者下肢深静脉血栓发生情况,以及对应的预防及护理.结果 通过对患者进行术前教育、术后的功能锻炼以及相关的护理措施,本组研究中无1例发生下肢深静脉血栓.结论 早期有针对性的治疗和护理可以有效预防下肢深静脉血栓的发生.     

髋关节置换术后下肢深静脉血栓形成的预防性护理干预

目的:探讨髋关节置换术后预防下肢深静脉血栓形成(DVT)的护理对策.方法:通过对56例髋关节置换术后患者的护理进行总结,分析髋关节置换术后下肢深静脉血栓形成的因素,通过早期采取积极主动的护理方法,预防髋关节置换术后下肢深静脉血栓形成.结果:56例患者开展预防性护理干预后,无1例下肢深静脉血栓出现,只有3例出现术后局部血肿、胀痛,经过及时治疗、护理,患者症状缓解.结论:采取合理可靠的预防性护理措施,可减少髋关节置换术后深静脉血栓的形成.     

髋关节置换术后下肢深静脉血栓的中医预防护理研究进展

本文对人工髋关节置换术后下肢深静脉血栓形成因素方面的研究进行综述,并提出从中医护理角度对人工髋关节置换术后下肢深静脉血栓的形成落实预防护理措施,以提高护理人员对下肢深静脉血栓形成因素的认知程度和预防重视程度,降低髋关节置换术后下肢深静脉血栓形成的发生,减轻患者痛苦,提高临床护理质量。     

护理干预在人工髋关节置换术后下肢深静脉血栓预防中的效果

目的：研究护理干预在人工髋关节置换术后下肢深静脉血栓预防中的效果。方法：选取2009年12月~2013年12月于本院进行人工髋关节置换术治疗的68例患者,分为对照组34例和观察组34例,对照组给予常规护理,观察组在常规护理基础上给予早期护理干预,对比观察2组患者下肢深静脉血栓形成的发生情况。结果：2组比较,观察组患者的下肢深静脉血栓形成的发生率(2.94%),明显低于对照组(17.65%),P＜0.05,差异具有统计学意义。结论：护理干预在人工髋关节置换术后下肢深静脉血栓预防中的效果好,可明显降低下肢深静脉血栓形成发生率,减轻患者痛苦,值得临床广泛推广应用。     

髋关节置换术后预防下肢深静脉血栓的护理

目的:观察护理干预对预防髋关节置换术后患者下肢深静脉血栓形成的效果,探讨有效的防护措施。方法:选择我科收治的38例行髋关节置换术患者,分析髋关节置换术后深静脉血栓的形成因素,采取护理方法早期干预,减少血栓形成。结果:38例患者中发生深静脉血栓3例,发生率7.89%,经及时治疗,症状减轻。结论:掌握合理的防护措施可以减少髋关节置换术后血栓的形成。     

髋关节置换术后下肢深静脉血栓的预防及护理措施

目的研究分析髋关节置换术后下肢深静脉血栓的预防及护理措施。方法选取2012年1月~2015年5月我院在我院实施髋关节置换术患者68例,随机将患者分为观察组与对照组,每组34例。对照组给予患者常规的护理措施,观察组在对照组患者的护理基础上加入深静脉血栓的预防护理。观察并比较两组患者在髋关节置换术后下肢深静脉血栓的预防及护理效果。结果观察组患者髋关节置换术后深静脉血栓发生率显著低于对照组患者,(P0.05)差异具有统计学意义。观察组患者临床护理满意度显著高于对照组患者,(P0.05)差异具有统计学意义。结论对于髋骨关节置换术患者在围术期实施深静脉血栓预防护理,可效降低术后下肢深静脉血栓的发生率,提高患者及其家属对护理服务的满意度,值得在临床上广泛的推广应用。     

无柄人工全髋关节置换术后下肢深静脉血栓形成的预防及护理

目的:探讨无柄人工全髋关节置换术后患者的护理方法,降低无柄人工全髋关节置换术后下肢深静脉血栓形成(DVT)的发生率。方法:总结62例无柄人工全髋关节置换术后的护理经验。从病因出发,采取针对性的预防护理措施,包括术前评估,抬高患肢,减少局部压迫,早期积极活动,指导并协助患者进行早期功能锻炼,采取预防性的抗凝治疗,以促进静脉回流等,并在护理过程中注意观察患肢血液循环情况,一旦有DVT发生,及早治疗。结果:无柄人工全髋关节置换术62例中,仅4例发生DVT,发生率为6.45%。结论:明确病因,采取预防性的护理措施,可大幅度地降低无柄人工全髋关节置换术后DVT的发生率。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.