安全护理在重症肌无力患者护理过程中的应用价值

目的:探讨安全护理在重症肌无力患者护理过程中的应用价值.方法:将医院收治的重症肌无力患者94例作为研究对象,随机分为观察组47例及对照组47例.对照组患者采取常规护理,观察组患者在此基础上实施安全护理,比较两组患者危象发生率、并发症发生率及生存质量.结果:观察组患者危象发生率、并发症发生率均要低于对照组(P<0.05);干预后,观察组SF-36各维度评分要高于对照组(P<0.05).结论:对重症肌无力患者实施安全护理能够有效预防危象、并发症,并能够提升患者生存质量,值得推广.     

Pathogenesis of myasthenia gravis

Myasthenia gravis is a neuromuscular, autoimmune, and acquired disturbance characterized by weakness and fatigue of skeletal muscles. During the past two decades, remarkable progress has been made in the understanding of myasthenia gravis, and the new knowledge has been applied directly to the clinical diagnosis and treatment of this formerly severe disease. Myasthenia gravis is undoubtedly the most thoroughly understood of all human autoimmune diseases and has served as a model for the elucidation of mechanisms underlying other autoimmune disorders. In this review we mention the most important physiopathological aspects and its application in the clinic practice.     

重症肌无力患者肺部感染临床分析

目的分析重症肌无力患者肺部感染相关因素,以采取有效的控制措施。方法对2004年1月1日-2009年12月31日出院的60例重症肌无力患者的肺部感染危险因素、病原菌等进行回顾性调查分析。结果 60例发生了下呼吸道感染,45例患者发生了不同程度的肺部感染,肺部感染率为75.00%;病原学检查为条件致病菌;基础疾病、大剂量激素的应用、侵入性操作、抗菌药物预防性应用、住院天数等因素与肺部感染的发生相关。结论重症肌无力患者的肺部感染发生率高,应积极重视与医院感染发生的相关因素,采取积极有效的防治措施,减少肺部感染发生率,促进患者康复。     

Association of coeliac disease and myasthenia gravis

Coeliac disease is a malabsorption syndrome induced by the gluten-containing cereals leading to the damage of small intestinal mucosa. A case of a young woman is presented whose coeliac disease became overt in the puerperium. Despite strict adherence to gluten-free diet, her muscle weakness affecting several muscle regions persisted. Following a diagnostic work-up covering numerous co-disciplines, the diagnosis of myasthenia gravis was set up underlying her muscle symptoms. After the thorough review of the corresponding literature, the authors could not find any case report on the association of coeliac disease with myasthenia gravis.