颊部外周型牙源性角化囊肿2例

外周型牙源性角化囊肿十分罕见,位于颊部软组织内的外周型牙源性角化囊肿更为罕见。本文报道2例颊部软组织内的外周型牙源性角化囊肿,并结合相关文献进行讨论。     

颊黏膜牙源性角化囊肿病例报告及文献回顾

牙源性角化囊肿是一种多发生于颌骨,呈侵袭性生长,且复发率高的牙源性良性病损。一类原发于颌骨外软组织,且具有OKC组织学特点的病变被称为外周性牙源性角化囊肿(peripheral odontogenic keratocyst, POKC)。本文报道1例右颊黏膜POKC,并就临床特点和起因等进行文献回顾。     

基底细胞痣综合征的牙源性角化囊肿中Ki-67表达的研究

目的：探讨基底细胞痣综合征的牙源性角化囊肿细胞增殖活性与临床生物学行为的关系。方法：利用Ki-67单克隆抗体，免疫组化方法（LSAB法）检测基底细胞痣综合征的牙源性角化囊肿和非综合征的牙源性角化囊肿中Ki-67表达情况。结果：Ki-67在基底细胞痣综合征的牙源性角化囊肿衬里上皮中的表达主要位于基底上层，且明显高地单发和复发牙源性角化囊肿，结论：基底细胞痣综合征的牙源性角化囊肿较非综合征的角化囊肿具有更高的细胞增殖殖活性，与其较高的复发潜能有关。     

牙源性角化囊肿囊液和患者血清中sIL-2R水平的初步研究

目的　检测可溶性白细胞介素 2受体 (sIL - 2R)在牙源性角化囊肿患者囊液和血清中的表达 ,探讨其在角化囊肿发生、发展中的作用及临床病理意义。方法　应用双抗体夹心ELISA法对 18例牙源性角化囊肿患者囊液和血清中sIL - 2R进行检测。结果　角化囊肿患者囊液及血清中sIL - 2R水平高于其他颌骨囊肿 ;角化囊肿术后复发患者囊液和血清中sIL - 2R水平高于初发者。结论　角化囊肿囊液中高浓度sIL - 2R存在与角化囊肿具有高复发倾向关系密切     

开窗术治疗牙源性角化囊肿

Philipsen(1956年)提出将具有角化上皮的牙源性囊肿称为“牙源性角化囊肿”。1971年WHO简化囊肿的分类,将始基囊肿和角化囊肿归为一类,但不是所有的始基囊肿都是角化囊肿。牙源性角化囊肿占颌骨囊肿的3％～     

位于牙根侧方的牙源性角化囊肿

Philipsen首先使用牙源性角化囊肿这一术语来描述一系列的有角化的颌骨囊肿,他认为这些囊肿是牙源性的,后来许多学者描述了牙源性角化囊肿odontogenic keratocyst(OKC)的临床和组织学特征。有时OKC也发生在根侧方牙周部位。Fantaria研究了46例根侧牙周囊肿,发现其中8例(17%)是OKC。Gold和Sliwkowski研究32例发现6例(19%)是OKC。Brannon也发现82例牙周囊肿中20例(24.4%)是OKC。本文目的是讨论并区别牙周囊肿和OKC的重要性。 OKC是起源于牙齿的发育性囊肿,可发生在颌骨的任何部位。下颌较上颌常见,     

牙源性角化囊肿发生的实验研究

摘要 目的:探讨牙源性角化囊肿的组织由来。方法:将小鼠胎仔的牙板与牙乳头、口腔粘膜上皮与牙乳头,以及牙胚制成移植片,分别移植到同系成鼠的肾被膜下,定期回收组织片,进行组织病理学观察。结果:发现58例移植片中,41例形成角化囊肿,45例伴有牙体组织形成。结论:实验产生的角化囊肿在组织学上与人的牙源性角化囊肿十分相似,可以为进一步研究该囊肿提供一个较理想的动物模型;证实了牙源性上皮可以发生角化;提示了牙板、口腔粘膜上皮和外釉上皮可能是该囊肿的组织由来之一。     

颌骨牙源性角化囊肿的X线诊断：附66例分析

颌骨牙源性角化囊肿的Ｘ线诊断（附６６例分析）南京市口腔医院放射科王铁梅，吴定，廖波在颌骨单囊性、多囊性病变中牙源性角化囊肿甚为常见，其Ｘ线表现影象复杂，常易与其它牙源性囊肿及肿瘤相混淆。且角化囊肿较易复发。因此，为了提高对本病的认识，进一步准确地为临...     

392例颌骨角化囊肿临床分析

颌骨牙源性角化囊肿临床较多见，由于其发生发展早期较难发现，对颌骨及牙齿破坏较大。本文对我院1980年～2005年1月收治经病理确诊的颌骨牙源性角化囊肿392例的临床表现、治疗方式作一回顾性分析。     

牙源性角化囊肿感染及与术后并发症、复发间关系初探

84例牙源性角化囊肿 ,通过临床 X线 ,术后组织病理观察 ,对其感染 ,感染与术后并发症 ,与复发间关系进行初探。结果显示 :角化囊肿感染率高达 6 5 .5 % ,临床颌骨囊肿伴感染时 ,应考虑到角化囊肿可能性大。术前囊肿伴感染者术后并发症的发生远高于术前无感染者 ,两组间差异显著 (P<0 .0 5 )。故角化囊肿应注意给予抗感染治疗。但术前伴感染者与非感染者相比 ,复发率无明显差异。显示牙源性角化囊肿的炎性感染与复发间的内在联系 ,是值得进一步探讨的课题     

Soft tissue aneurysmal bone cyst of the mandible: Report of a case

We report the case of a 17-year-old boy with a soft tissue aneurysmal bone cyst (STABC) located in the posterior aspect of the right mandible. Conventional radiography revealed no positive findings. On the computed tomography scan, the lesion appeared to have a non-uniform intralesional density. Magnetic resonance imaging revealed an abnormal soft tissue masses with cystic component in the superficial part of right mandibular body and angle with intact cortex. Following histopathological examination, fibro-histiocytic proliferation, blood-filled spaces and multinucleated giant cells were seen and the lesion was diagnosed as a STABC. The mass together with underlying bone and periosteum on its periphery was surgically resected under general anesthesia. Thirty-six months after surgery the patient was assessed at outpatient clinic and found no sign of recurrence This may be only the first reported case of the mandible in the English literature of this extremely rare benign tumor occurring in soft tissue.     

Peripheral odontogenic keratocyst: report of two cases and review of the literature

The odontogenic keratocyst is a developmental odontogenic cyst most commonly occurring in the jaws. In rare instances, however, this lesion has been reported to occur in the gingival soft tissues. Although most authors have regarded these soft tissue lesions to be peripheral odontogenic keratocysts, others have preferred to regard them as histopathologic variants of the gingival cyst of the adult. We document 2 additional cases occurring in the gingival soft tissues, and we review the existing literature concerning this unusual lesion. Given the distinct microscopic features and possible association with nevoid basal cell carcinoma syndrome, we favor the view that this lesion represents the soft tissue counterpart of the intraosseous odontogenic keratocyst.     

Multiple progressive eosinophilic granuloma of the jaws

A case of eosinophilic granuloma occurring in the jaws is reported, and the clinical and microscopic features of this entity are discussed.In this case, the lesions were progressive and ultimately involved large areas of the mandible and a small area in the maxilla. Early manifestations of the disorder were believed to be inflammatory, and consequently there was a significant delay in treatment. Curettage of the mandibular lesions followed by low-dose radiation therapy has apparently been effective. Twenty-four months after treatment, there is no evidence of soft tissue involvement or recurrent lesions in bone.     

Malignant fibrous histiocytoma of the maxilla. Case report and review of the literature

A case of malignant fibrous histiocytoma (MFH) occurring in the maxilla is presented. Although MFH is now recognised as the most common soft tissue sarcoma of late adult life, it rarely occurs in bone and then more usually in the long bones. Presentation affecting the facial bones and skull is extremely rare, but should be considered in the differential diagnosis of bone tumours affecting the maxilla. Skeletal lesions appear more aggressive than those in soft tissues. Early radical excision is the treatment of choice although radiotherapy for inoperable tumours may lead to regression, as in the case presented here.     

Osteolipoma of the buccal mucosa: a case report

Lipomas are benign mesenchymal neoplasms of soft tissue that can be found commonly in any part of the human body. Their presence in the oral mucosa is uncommon, however, with approximately 4% of the cases occurring in the oral cavity. Oral lipomas are likely to have originated from mature adipose tissue and there are several histological variants of lipomas described, which are identified according to the predominant type of tissue in addition to adipose tissue. A rare lipoma variant, known as an osteolipoma or an ossifying lipoma, may occur; however, little has been written this type of lipoma characterized by a classical lipoma with areas of osseous metaplasia. This paper describes a case of an osteolipoma involving the buccal mucosa of an adult patient.     

Malignant peripheral nerve cell tumour

Malignant Peripheral Nerve Sheath Tumour (MPNST) also termed as spindle cell malignancy of the peripheral nerve schwann cell or neurogenic sarcoma represents 10% of all soft tissue sarcomas. The tumour is usually found in lower extremities and only 10% to 20% of all lesions occur in head and neck region thus making it a rare entity. Central involvement, particularly in the jaw bones is quite unusual. Neurofibroma is one of the common nerve sheath tumours occurring in the soft tissues and generally appears in neurofibromatosis I (NF-I or von recklinghausen’s disease). MPNST are uncommon sarcomas that almost always arise in the soft tissues. Here we report a case of intraosseous peripheral nerve sheath tumour occurring in the mandible and discuss the surgical management with adjuvant and neoadjuvant treatment plan.     

Extraskeletal chondroma of the masseter muscle: a case report with review of the literature

The authors report a case of soft tissue chondroma of the masseter muscle in a 49- year-old man. The tumour was entirely composed of lobules of hyaline cartilage. The literature on head and neck soft tissue chondroma is also reviewed. To the authors’ knowledge, this is the first case of muscular soft tissue chondroma in the head and neck region.     

Embryonal rhabdomyosarcoma: presentation as a parotid gland mass

Solid tumors occur infrequently during childhood. Rhabdomyosarcoma is the most common soft tissue sarcoma occurring in children. Therapeutic advances during the last 15 years have lead to a vast improvement in cosmetic and functional results and in overall survival. A case report of rhabdomyosarcoma of the parotid gland and a review of the literature are presented to highlight these advances.     

Malignant fibrous histiocytoma of scalp with intracranial invasion 20 years after postoperative irradiation

We report a case of malignant fibrous histiocytoma with intracranial invasion occurring 20 years after radiation therapy for astrocytoma. Magnetic resonance imaging suggested that a dumbbell-shaped tumor arising from soft tissue was pressing the brain. Histopathological findings revealed a storiform pattern with spindle cells such as fibroblasts, histiocytes, epithelioid cells with irregularly shaped nuclei, and bizarre giant cells. Three operations involving craniectomy were necessary because of recurrence.