共查询到20条相似文献,搜索用时 0 毫秒
1.
K Hameed 《Archives of pathology》1966,81(5):465-468
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H E Wyandt L Bugeau-Michaud J C Skare A Milunsky 《American journal of medical genetics》1991,40(3):280-283
We report clinical and cytogenetic findings on a 24-year-old woman with short stature, irregular menses, and other anomalies suggestive of Ullrich-Turner syndrome (UTS). Chromosome analysis documented a de novo duplication of Xp21 without any apparent microscopic deletion. DNA studies showed that part of band Xp22.1 is also duplicated. The clinical findings are compared with 5 other patients with dup(Xp). 相似文献
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Intrahepatic bile duct adenoma (peribiliary gland hamartoma): a case report and review of literature
Jianguo Wei Dongmei Zhang Jianfeng Yang Chunwei Xu 《International journal of clinical and experimental pathology》2015,8(5):5908-5913
Bile duct adenoma (BDA) is a comparatively rare disease and there are relatively few reported cases in the English-language literature. Herein, we present a 63-year-old woman, who was incidentally found to have a liver-occupying lesion during a routine medical examination. Ultrasonography suggested “quick wash-in and wash-out” sign with an obvious nodular enhancement in the peripheral of the right intrahepatic nodular. Computed tomography revealed a 33 mm×25 mm×28 mm mass in the right hepatic segment. The patient underwent a liver tumor resection. Histological examination showed that the tumor was consisted of small heterogeneous tubular ducts with fibrous tissues and several inflammatory cells, without cell atypia and mitotic activity. Immunohistochemically, the tumor cells were positive for CK19, CK7, CD56 and CD10. The final histopathological diagnosis was intrahepatic BDA. 相似文献
4.
后肾性腺瘤3例报道并文献复习 总被引:3,自引:0,他引:3
目的:探讨后肾性腺瘤的病理形态学特征及诊断要点。方法:采用常规HE染色及免疫组化染色,并复习文献。结果:组织学上主要由紧密而规则排列 的圆形小管和含有圆形细胞巢的实性区相间排列,偶见肾小球样结构。免疫组化以Leu7、vimetntin、keratin阳性及EMA阴性为特点。结论:后肾性腺瘤是肾胚胎残留发生的罕见良性肿瘤,常被误诊为恶性肿瘤,故与肾母细胞瘤、乳头状肾细胞癌鉴别尤为重要。 相似文献
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Y Deugnier B Turlin D Léhry J R Pennarun P Verger B Launois M P Ramée 《Archives of pathology & laboratory medicine》1991,115(9):915-917
We report a case of malignant melanotic melanoma involving the extrahepatic biliary tract in a 34-year-old white woman. The diagnosis was established using conventional light microscopic examination and immunohistochemical stains. The clinical absence of any primary cutaneous or visceral melanoma suggests that the tumor arose primarily from the biliary tract. To our knowledge, only two previous cases of malignant melanoma of the common bile duct have been reported in the literature. 相似文献
7.
We describe a rare case of apocrine adenoma of the breast in a 45-year-old man. The patient presented with a tender lump in his left breast that had been present for 6 months. A mammogram identified a 3-mm nodular density in the breast, which was described as a hypoechoic nodule on ultrasound. Microscopic examination of tissue from an excisional biopsy revealed a 3-mm group of benign glands with abundant granular, eosinophilic cytoplasm and apical luminal blebbing, consistent with an apocrine adenoma. After reviewing other reported apocrine adenomas in the literature, we determined that our case was the smallest detected apocrine adenoma to be reported to date. 相似文献
8.
Kunju LP 《Archives of pathology & laboratory medicine》2010,134(10):1455-1459
Nephrogenic adenoma, also referred to as nephrogenic metaplasia, is an uncommon benign lesion of the urothelial tract, characterized by a circumscribed proliferation of tubules, cysts, and papillae lined by cells with low cuboidal to columnar epithelium. The diagnostic features that are useful in the recognition of this benign entity are the characteristic mixture of various architectural patterns, associated stromal edema and inflammation, hyaline sheath around tubules, eosinophilic colloidlike secretion within tubules, and lack of mitotic activity. Nephrogenic adenoma can be a significant diagnostic pitfall as certain histologic features, such as the presence of enlarged nuclei with prominent nucleoli, degenerative nuclear atypia, tiny tubules with blue mucin simulating signet ring cells, and focal invasion into superficial muscle, when taken out of context, can mimic malignancy. Herein, I report a case of nephrogenic adenoma with some worrisome histologic features and review the diagnostic criteria as well as pertinent morphologic malignant mimics of nephrogenic adenoma. 相似文献
9.
Plemorphic adenoma mainly occurs in the salivary glands. A similar tumor arising in the bone is extremely rare, and only three cases have been reported so far. Here, we present an additional case of primary plemorphic adenoma of bone; describe its clinical, pathological and radiological features; and compare them with those of the reported cases. 相似文献
10.
Two patients with villous polyps of the prostatic urethra are described. The article supports previous observations that the lesion has the morphologic appearance of prostatic tissue. A review of the literature reveals that this rare lesion appears to be specific for the prostatic urethra and behaves as a benign tumor. 相似文献
11.
乳头汗腺瘤样腺瘤1例及文献复习 总被引:2,自引:0,他引:2
目的 探讨乳头汗腺瘤样腺瘤的临床病理和免疫表型特点及诊断与治疗。方法 通过HE及免疫组化染色观察1例乳头汗腺瘤样腺瘤,并结合文献讨论。结果 肿瘤发生于乳头,由上皮细胞形成的不规则巢、小条索或小管在致密的纤维间质及平滑肌之间呈浸润性生长,其中可见“蝌蚪状”细胞巢及角化囊肿,病变边界不清。免疫表型:CK阳性,p63、SMA部分阳性,ER、PR及GCDFP-15均阴性。结论 乳头汗腺瘤样腺瘤是一种呈局部浸润性生长的非常罕见的乳头部良性肿瘤,局部切除后可复发,但不转移。组织学上主要应与乳头管腺瘤、导管内乳头状瘤伴鳞化及管状癌鉴别。适当的治疗应该包括肿瘤及其周边充分的正常组织完整切除,且标本切缘阴性。 相似文献
12.
Pleomorphic adenoma of the breast (PAB) is a very rare neoplasm. Although quite unique in its morphology, PAB shares some similarities with adenomyoepithelioma and is considered by some authors as a variant of this entity. Cytologic diagnosis of this lesion can be very challenging, especially when limited sampling is available. The differential diagnosis of PAB includes metaplastic carcinoma. On cytologic material, fibroadenoma and phyllodes tumor should also be considered within the differential diagnosis. We report the findings in a case of PAB, initially misdiagnosed as mucinous carcinoma on fine-needle aspiration, and review the literature regarding this entity. Correct identification of this benign mammary neoplasm is important to avoid unnecessarily aggressive treatment. 相似文献
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Villous adenoma of the bladder 总被引:1,自引:0,他引:1
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The concurrence of the intracranial multiple primary tumors (MPTs) consisting of acoustic neuroma (AN) and pituitary adenoma is very rare. Here, we report a 42-year-old female who presented with left AN associated with pituitary adenoma. A total of three such cases have been reported before and which also presented with left AN with pituitary adenoma. Recently, a new "field cancerization" model has been proposed, which could explain MPTs and is consistent with the pathogenesis of such cases. The model also indicates that when a pituitary tumor or AN is detected separately, we might consider the development of "expanding field" after oncological treatment especially after radiotherapy in order to prevent the second field tumor occurring. 相似文献
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目的:探讨气管多形性腺瘤的临床病理特征、诊断和鉴别诊断.方法:分析l例气管多形性腺瘤的临床病理资料、病理结果,并复习文献.结果:肿物大小2.5cm×1.5cm×1.0 cm,表面光滑,不规则结节状,切面灰白,半透明,质软韧,无明显出血和坏死.光镜下由上皮组织和间质组织两种成分构成,上皮细胞呈巢状、条索状及梁状漂浮在软骨黏液样间质背景中,局灶可见到腺样结构,细胞胞浆嗜酸性,无明显细胞异型性和核分裂象.免疫组织化学检查肌上皮细胞CK,S-100和P63阳性表达.腺上皮CK,CK7和CK19标记阳性.结论:气管多形性腺瘤少见,诊断气管内肿瘤时要考虑到这个鉴别诊断,以免漏诊或误诊.未来需要研究更多气管多形性腺瘤病例以进一步完善其临床进程、生物学行为和预后. 相似文献
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Villous adenomas are extremely rare tumors in the vagina and are indistinguishable from their colonic counterparts. These are considered as enteric type neoplasms of lower female genital tract arising from cloacal remnants. The significance of this lesion lies in the fact that it has to be distinguished from metastatic adenocarcinoma from other sites. We present a case of villous adenoma of vaginal vault, a rare site of presentation in a 30-year-old female. 相似文献
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乳头部腺瘤的临床病理观察 总被引:1,自引:0,他引:1
目的 探讨乳头部腺瘤的临床病理形态学及免疫表型特点、诊断及鉴别诊断.方法 应用光镜观察、免疫组织化学EnVision两步法等对18例乳头部腺瘤进行分析,并复习文献.结果 肿瘤局限于乳头或乳晕下,多数与表皮相连,主要由扩张的导管与纤维化间质组成,腺上皮不同程度增生,多数为复层或有实性巢状、筛状、乳头状或微乳头状等复杂结构,细胞杂乱、拥挤、重叠,导管周围存在完整肌上皮;有时间质明显纤维化、硬化.免疫组织化学染色显示34βE12上皮阳性,CK5/6上皮与肌上皮片状阳性,p53和c-erbB-2阴性,p63、平滑肌肌动蛋白、Calponin等染色显示导管周围存在完整肌上皮.结论 乳头部腺瘤是少见的良性肿瘤,常表现为硬化性乳头状瘤病、乳头状瘤病型腺病或旺炽型硬化性腺病等形态,易与导管上皮不典型增生/导管内癌、浸润性导管癌、低度恶性腺鳞癌等混淆;应密切结合肿瘤部位及形态学,辅之以免疫组织化学诊断. 相似文献
18.
乳头部腺瘤的临床病理观察 总被引:1,自引:0,他引:1
目的 探讨乳头部腺瘤的临床病理形态学及免疫表型特点、诊断及鉴别诊断.方法 应用光镜观察、免疫组织化学EnVision两步法等对18例乳头部腺瘤进行分析,并复习文献.结果 肿瘤局限于乳头或乳晕下,多数与表皮相连,主要由扩张的导管与纤维化间质组成,腺上皮不同程度增生,多数为复层或有实性巢状、筛状、乳头状或微乳头状等复杂结构,细胞杂乱、拥挤、重叠,导管周围存在完整肌上皮;有时间质明显纤维化、硬化.免疫组织化学染色显示34βE12上皮阳性,CK5/6上皮与肌上皮片状阳性,p53和c-erbB-2阴性,p63、平滑肌肌动蛋白、Calponin等染色显示导管周围存在完整肌上皮.结论 乳头部腺瘤是少见的良性肿瘤,常表现为硬化性乳头状瘤病、乳头状瘤病型腺病或旺炽型硬化性腺病等形态,易与导管上皮不典型增生/导管内癌、浸润性导管癌、低度恶性腺鳞癌等混淆;应密切结合肿瘤部位及形态学,辅之以免疫组织化学诊断. 相似文献
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Nonsyndromatic paucity of intrahepatic bile ducts in congenital syphilis. A case report 总被引:1,自引:0,他引:1
H Sugiura M Hayashi R Koshida R Watanabe Y Nakanuma G Ohta 《Acta pathologica japonica》1988,38(8):1061-1068
The first case of nonsyndromatic paucity of the intrahepatic bile ducts is reported in congenital syphilis. The patient, a 2-week-old female, was born at the 31st week of gestation, weighing 1,910 g. She had a high titer of IgM antibody to Treponema pallidum and sera from both parents also showed a positive reaction in the hemagglutination test for Treponema pallidum. The patient had hepatosplenomegaly and increasing jaundice, and died of respiratory failure on the 70th hospital day. Autopsy examination revealed paucity of the intrahepatic bile ducts, prominent giant cell transformation of hepatocytes, cholestasis and extramedullary hematopoiesis of the liver. The ratio of the number of intrahepatic bile ducts to that of the portal tracts was approximately 0.2:1. There was marked proliferation of atypical bile ductules at the margin of the portal tracts. The exact relation of this paucity to Treponema pallidum remains unknown. 相似文献