ACUPUNCTURE EFFECT ON GENE EXPRESSION OF c-fosmRNA, ppENKmRNA, iNOSmRNA AND iNOS ACTIVITY IN THE MOUSE SPINAL CORD

Ｉｔｗａｓｒｅｐｏｒｔｅｄｔｈａｔｔｈｅｍｅｔｈｉｏｎｉｎｅｅｎｋｅｐｈａｌｉｎｉｍｍｕｎｏｒｅａｃｔｉｖｉｔｙ(ＭＥＫＩＲ)ａｎｄｌｅｕｃｉｎｅｅｎｋｅｐｈａｌｉｎｉｍｍｕｎｏｒｅａｃｔｉｖｉｔｙ(ＬＥＫＩＲ)ｗｅｒｅａｔｔｅｎｕａｔｅｄｉｎｔｈｅｇｕｉｎｅａｐｉｇ’ｓｓｐｉｎａｌｃｏｒｄａｆｔｅｒａｃｕｐｕｎｃｔｕｒｅｉｎｏｕｒｐｒｅｖｉｏｕｓｅｘｐｅｒｉｍｅｎｔ,ｓｕｇｇｅｓｔｉｎｇｔｈａｔａｃｕｐｕｎｃｔｕｒｅｍａｙｉｎｄｕｃｅｔｈｅｒｅｌｅａｓｅｏｆＭＥＫａｎｄＬＥＫｆｒｏｍｔｈｅｓｐｉｎ…     

EFFECTS OF ACUPUNCTURE ON THE CONTENTS OF ENKEPHALINS IN DIFFERENT BRAIN REGIONS AND CORTICOSTERONE IN PLASMA OF RATS WITH ENDOTOXIN SHOCK

In this experiment,we have observed the effects of acupuncture on the contents ofenkephalins in different brain regions and corticosterone in plasma of rats with endotoxin shock.Theresults showed that after acupuncture the endogenous enkephalins were significantly decreased(P<0.05)in the midbrain and brain stem of endotoxin shock rats,suggesting the anti-shock of acupuncture might be related to the enkephalins in the midbrain and brain stem.In addition,there was a rising trend in plasma corticosterone of the rats with toxic shock.     

针刺、中药、针药结合戒毒的疗效对比

目的 比较针刺、中药、针药结合疗法对海洛因依赖者戒断的临床疗效。方法 对96例海洛因依赖者以上述三种疗法戒断，并与西药对症治疗对照，动态观察20d的戒断症状记分。结果 戒断治疗48h时，针刺组与西药对照组比较P＜0．05；治疗到72h时针刺组优于其他各组；P＜0．05－P＜0．01。但各组在戒断前3d均不能完全改善戒断症状。结论 针刺、中药、针药结合疗法脱毒具有一定疗效，以针刺疗法效果明显，但均不能完全改善激烈的戒断症状。针刺与中药的结合不一定都出现协同效应。     

EFFECTS OF ACUPUNCTURE ON THE HIGH HEMAGGLUTINATION STATE, BLOOD-SUGAR-RAISING HORMONE AND IMMUNOCYTE FACTOR LEVELS IN TYPE-II DIABETES PATIENTS

Ｔｈｅｐｒｅｓｅｎｔｓｔｕｄｙｉｓａｉｍｅｄｔｏｒｅｓｅａｒｃｈｔｈｅｅｆｆｅｃｔｏｆａｃｕｐｕｎｃｔｕｒｅｏｎｈｉｇｈｈｅｍａｇｇｌｕｔｉｎａｔｉｏｎｓｔａｔｅ,ｂｌｏｏｄ ｓｕｇａｒ ｒａｉｓｉｎｇｈｏｒｍｏｎｅａｎｄｉｍｍｕｎｏ ｃｙｔｅｆａｃｔｏｒｓａｎｄｔｏｅｌｕｃｉｄａｔｅｉｔｓｍｅｃｈａｎｉｓｍｓｉｎｔｒｅａｔｍｅｎｔｏｆｔｙｐｅ ＩＩｄｉａｂｅｔｅｓｆｒｏｍｔｈｅｖｉｅｗ ｐｏｉｎｔｓｏｆｔｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅｍｅｄｉｃｉｎｅｔｈａｔ“ｐｒｏ ｍｏｔｉｎｇｂｌｏｏｄｃｉｒ…     

电针对局灶性脑缺血／再灌注大鼠大脑皮层IL—1RImRNA和蛋白表达的调节

目的 观察脑缺血对IL－1RI的表达及电针对其表达的调节。方法 采用SD大鼠大脑中动脉线栓法制备MCAO缺血模型,应用原位杂交和免疫组化的方法观察脑缺血及电针对大鼠大脑皮层白细胞介素－1受体（Ⅰ型）（interleukin-1 receptor type Ⅰ,IL-1RI)mRNA和蛋白表达的影响。结果 在正常及假手术大鼠IL－1RImRNA和蛋白阳性细胞在皮层呈基础水平表达;脑缺血再灌注后2hIL-1RImRNA阳性细胞表达增加,6h达高峰。脑缺血后IL－1RI蛋白在缺血侧皮层表达明显增加,再灌注后12h达高峰。电针可显著降低MCAO大鼠大脑皮层IL－1RImRNA和蛋白的表达。结论 脑缺血后IL－1RImRNA和蛋白表达增加,电针可降低IL－1RImRNA和蛋白的表达,从而减轻缺血后IL－1β导致的缺血性脑损伤。