老年患者腹腔镜胆囊切除术与开腹胆囊切除术比较

目的对比研究老年良性胆囊疾病腹腔镜胆囊切除(laparoscopic cholecystectomy,LC)与开腹胆囊切除(open cholecystectomy,OC)安全性,为老年人胆囊切除术式的选择提供依据. 方法 60岁以上有胆囊切除适应证且耐受全麻的老年患者120例,按住院顺序单双号分为LC组和OC组,每组60例,比较手术时间、止痛剂使用情况、术后胃肠功能恢复时间、输液时间、卧床时间、术后并发症、住院时间等围手术期指标,比较2组总T3、TSH水平,腹肌功能恢复等康复指标. 结果术后并发症、围手术期以及康复指标,LC组均优于OC组.TT3与术前相比,LC组(F=8.26,P=0.000)、OC组(F=124.70,P=0.000)均明显下降,OC组下降理明显;TSH与术前相比,LC组下降不明显(F=1.87,P=0.157),OC组下降明显(F=27.24,P=0.000).术后7 d直腿抬高试验次数LC组明显高于OC组(t=3.640,P=0.000) 结论老年良性胆囊疾病患者行LC优于OC.     

腹腔镜胆囊切除术与开腹胆囊切除术的临床比较研究

目的比较腹腔镜胆囊切除术与开腹胆囊切除术的疗效和安全性。方法将我院2008年6月～2010年6月收治的96例胆囊疾病患者随机分为观察组（腹腔镜胆囊切除术）和对照组（开腹胆囊切除术）各48例,术后比较两组的手术时间、术中出血量、术后排气时间及并发症情况。结果观察组的手术用时、排气时间、住院时间明显短于对照组（P〈0.05）,且观察组术中出血量明显少于对照组（P〈0.05）,术后观察组1例因胆囊三角区出血,镜下止血失败而中转开腹;1例术后伤口出现感染,对照组出现切口感染4例,胆心反射5例,切口出血4例,胆管损伤、肠粘连各1例,观察组术后并发症的发生率明显低于对照组并发症的发生率（P〈0.05）。结论腹腔镜胆囊切除术与传统开腹手术相比对患者损伤小,术后恢复快,住院时间短,但也存在一些术后并发症,但并发症的发生率较低。     

老年患者腹腔镜胆囊切除术与开腹胆囊切除术的临床对照研究

正伴随着我国老龄化社会的来临和人民生活医疗水平的提高,老年良性胆囊疾病的发生率在我国逐年升高,且有明显上升的倾向,老年患者胆囊疾病已成为基层医院普外科住院患者的常见疾病,对老年患者胆囊切除术术式的选择显得尤为重要。本研究资料选择2005年1月~2013年12月我院普外科病区60岁以上老年患者因胆囊良性疾病择期行胆囊切除术共200例,按手术方式不同分为两组,LC组105例,OC组95例,其中腹腔镜胆囊切除术中有两     

腹腔镜胆囊切除术与开腹胆囊切除术对肝功能影响的比较研究

目的 对腹腔镜胆囊切除术（LC）与开腹胆囊切除术（OC）手术前后肝功能的临床资料进行对比研究，旨在观察术后肝功能变化规律及两种术式对肝功能的影响有无差异，并为今后手术病例及术式选择提供依据。方法 选择胆囊良性病变且肝功能正常需行胆囊切除术者作为研究对象。将30例病人分为LC组和OC组，并分别按开放法或腹腔镜方法实施胆囊切除术。术前、术后第1、3、7天，分别取空腹外周静脉血测定肝功能指标，包括ALT、AST、TBIL、DBIL、GGT、ALB、ALP。结果 两组病人年龄构成及术前肝功能无显著差异，LC与OC术后各项指标变化趋势相同。LC与OC术后血清ALT、AST、TBIL均较术前升高；上述指标术后第3天即明显下降，至术后第7天达正常水平，且所有病人术后顺利恢复。LC与OC术后血清ALB均有下降，血清DBIL、GGT、ALP均无显著变化。结论 本研究结果表明：（1）LC与OC对肝功能均有影响，但仅为一过性现象，不影响病人恢复；（2）在全麻下，腹腔内气腹压力为12～15mmHg时，LC对肝功能的影响与OC相比无显著性差异，说明在此情况下施行LC是安全的。     

腹腔镜胆囊切除术与传统开腹胆囊切除术治疗胆囊结石临床疗效比较

目的 比较腹腔镜胆囊切除术与开腹胆囊切除术两种术式治疗胆囊结石的临床疗效.方法 选取2012年5月至2013年3月我院行手术治疗胆囊结石患者120例,其中60例行腹腔镜胆囊切除术作为观察组,开腹胆囊切除术手术治疗60例作为对照组.观察并比较两组临床疗效结果.结果 研究组术中出血量少于对照组,手术时间、胃肠道功能恢复时间及术后住院时间短于对照组,两组比较,差异有统计学意义（P＜0.05）;对照组、观察组术后并发症发生率分别为20％、5.0％,差异有统计学意义（P＜0.05）.结论 腹腔镜胆囊切除术具有创伤小、恢复快、住院时间短和并发症少等优点,值得临床推广.     

开腹胆囊切除术及腹腔镜胆囊切除术患者围手术期生理反应的比较研究

将需行胆囊切除的患者分为两组．每组各21例，分别行腹腔镜胆囊切除术（LC）及开腹胆囊切除术（OC）。从手术前后的肺功能测定、动脉血气分析、血清皮质醇、红细胞沉降率（ESR）、C反应蛋白以及术后尿液17－OHH皮质醇、尿素氮（BUN）的结果分析，LC组术后肺功能优于OC组，动脉血气分析无显著性差别，LC组患者应激反应水平低于OC组．术后氮丢失较OC组少，且LC组术后肛门排气时间、禁食天数、发热天数、输液天数及住院天数较OC组明显缩短。     

腹腔镜胆囊切除术的判别函数研究

目的：研究腹腔镜胆囊切除术(LC)的判别函数，用以指导胆囊切除病例在术前确定选用LC或开腹胆囊切除(OC)的手术方法。方法：实施408例LC，术前对每一例的33项招标进行逐一登记，术后采用逐步判别分析进行招标筛选，求出LC判别函数。结果：筛选出有判别意义的7项招标，在Bayes准则下求出二个判别函数。回代函数结果，总的判别正确率为95．1％。结论：凡胆囊切除术病例只要在术前将7项招标代入函数中，即可在术前确定该病例选用LC或是OC。     

糖尿病患者行腹腔镜胆囊切除术的临床体会

目的探讨糖尿病患者接受腹腔镜胆囊切除术(LC)的安全性及可行性。方法回顾性分析自2003年6月至2010年6月收治的胆囊结石合并糖尿病患者47例,均行四孔法完成LC,总结临床经验。结果行LC的47例糖尿病患者中,中转开腹1例,中转开腹率2.1%,与同期行LC手术总体中转开腹率比较,差异无统计学意义。结论糖尿病患者LC是安全的,具有住院时间短、创伤恢复快、术后并发症少的优点,应为首选术式。胆囊结石合并糖尿病患者,当血糖控制满意时,应尽早选择LC,对于胆囊炎合并糖尿病患者,积极有效控制血糖和感染后行LC。临床医师应尽可能避免糖尿病患者行LC时中转开腹。     

腹腔镜胆囊切除术和开腹胆囊切除术安全性临床分析

目的比较开腹胆囊切除术和腹腔镜胆囊切除术的安全性。方法回顾分析568例胆囊切除术病例。分为2组:A组为对照组,323例行开腹胆囊切除术;B组为实验组,245例行腹腔镜胆囊切除术。对比2组的手术成功率、手术时间、住院时间、术中及术后并发症发生情况。2组手术成功率之间比较用检验,2组手术时间和住院时间之间比较用t检验,P0.05差异有统计学意义。结果2组手术成功率之间,P0.05,差异无统计学意义;2组手术时间和住院时间之间比较,P0.05差异有统计学意义。结论术前正确选择病例、术中规范操作、术后注意观察可能出现的并发症是腹腔镜胆囊切除手术成功的关键。相比开腹手术而言,具有明显的优势。     

急诊高龄患者腹腔镜胆囊切除术和开腹胆囊切除术的临床对比研究

目的探讨急诊高龄患者腹腔镜胆囊切除术和开腹胆囊切除术的临床治疗效果。方法 101例高龄急诊胆囊炎患者分别施行腹腔镜胆囊切除(LC)和开腹胆囊切除(OC)两种手术方法治疗,LC组53例,OC组48例,观察手术恢复及并发症等情况。结果在手术时间、术中出血量、术后疼痛、肠道功能恢复时间、住院时间、并发症发生率等方面,LC组明显优于OC组。结论高龄患者急性胆囊炎行LC并发症少,创伤小、痛苦小、恢复快,高龄患者急性胆囊炎行LC是安全可行的,并具有微创的优势。     

腹腔镜与开腹胆囊切除术对比分析

我院于1994年8月～1996年6月完成腹腔镜胆囊切除术(LC)70例,为了客观地评价LC的优越性及不足之处,本文随机将1993年7月～     

胆囊结石并肝硬化行腹腔镜与开腹胆囊切除比较

目的对比合并肝硬化的胆囊结石症行腹腔镜胆囊切除与开腹胆囊切除术的疗效。方法回顾性分析我院1999～2004年25例合并肝硬化的症状性胆囊结石患者,其中13例行LC,12例行OC。结果13例LC患者1例出现肺部感染;12例OC患者术后切口感染1例,肺部感染3例,切口渗液4例,尿路感染3例;术中出血量LC组明显少于OC组P<0.0.5;术后住院时间LC组明显短于OC组P<0.0.5。结论LC治疗合并肝硬化的症状性胆囊结石症,具有明显的优点,与OC相比,LC手术时间短,手术出血量少,术后并发症发生率低,同时缩短了住院时间,在肝硬化ChildA鄄B级病人中安全可靠。     

腹腔镜与开腹胆囊切除术的住院费用对比

目的　比较腹腔镜与开腹胆囊切除术的住院费用。　方法　LC开展初期 ( 1991年 )和成熟期 ( 2 0 0 0年 )选取LC10 0例与同一时期开腹胆囊切除术 (OC) 10 0例住院费用进行对比分析。　结果　LC开展初期 ,LC组住院费用总费用( 2 575 86± 2 61 61)元明显高于OC组 ( 12 40 61± 3 82 67)元 (t=2 8 80 5,P <0 0 0 1) ,主要与手术及材料费用高 (t =199 83 3 ,P <0 0 0 1)有关。LC开展成熟期 ,LC组住院费用总支出 ( 583 3 0 0± 464 97)元明显低于OC组 ( 7489 2 6± 2 491 2 4)元 (t=6 53 5,P <0 0 0 1) ,虽然手术及材料支出仍高 (t=17 0 2 9,P <0 0 0 1) ,但药品、床位、检查等项均低于OC组 (t值分别为 8 83 9、12 0 0 5、6 2 0 3 ,P <0 0 0 1)。　结论　随着LC技术的成熟 ,费用降低已成为其一大特点     

A financial analysis of laparoscopic and open cholecystectomy

Laparoscopic cholecystectomy (LC) is now the method of choice in treatment of symptomatic gallstone disease. Despite its rapidly growing popularity, comparative costs of this new method and open cholecystectomy (OC) remain unclear. The most outstanding feature of laparoscopic cholecystectomy is the period of short recovery. In Sweden the social insurance office documents sick leave period, sickness allowance, as well as diagnosis and therefore provides a reliable basis for an economic analysis. The purpose of this study was to estimate the hospital cost and costs due to sick leave in a series of patients operated on with elective cholecystectomy using the two methods. In each group 50 consecutive patients were studied retrospectively. The total hospital cost was 10% lower in the laparoscopy group—$1,864 as compared to $2,030 per patient in the OC group. Median number of days off work was 14 after LC and 35 days after open surgery, which corresponds to a median sickness allowance of $516 per patient (LC) compared to $1,424 (OC). Laparoscopic cholecystectomy is more cost-effective than open cholecystectomy mainly due to a reduced sick leave period.     

Laparoscopic cholecystectomy in the elderly

Background Few studies have examined the results of laparoscopic cholecystectomy (LC) in the elderly. We reviewed our experience with the procedure in 194 patients age 65 and older. Methods A chart review was performed on patients who underwent attempted LC over a 4-year period. Age, conversion rate to open cholecystectomy (OC), length of stay, and morbidity and mortality rates were compared between elective and inpatients as well as between patients age 65–75 and patients over age 75. Results Conversion rate to OC was 10.6%. Mean length of hospital stay was 2.7 days. Morbidity and mortality rates were 18% and 1%. Elective patients experienced significantly fewer medical complications. There were no differences in complication rates between patients age 65–75 and patients over 75 years, but younger patients had a significantly shorter mean length of hospitalization. Conclusions Elderly patients experience more complications and longer lengths of stay than the general population. However, our results compare favorably with OC series in elderly patients. Presented at the annual meeting of the Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Orlando, Florida, USA, 11–14 March 1995     

Laparoscopic cholecystectomy for early gallbladder carcinoma: long-term outcome in comparison with conventional open cholecystectomy

Background The role of laparoscopic surgery for malignant gallbladder tumors remains uncertain. This study compared the surgical results of laparoscopic versus conventional open cholecystectomy for patients with early-stage gallbladder carcinoma and examined the role of laparoscopic surgery for early gallbladder carcinomas. Methods Data for the treatment of gallbladder carcinomas were gathered from Chang Gung Memorial Hospital (Linkou, Taiwan). A retrospective analysis of 40 patients with either stage 0 or stage 1 gallbladder carcinoma was performed. The patients were categorized into two groups on the basis of cholecystectomy procedures. The long-term outcomes for the two groups were compared. Results During the follow-up period, which ranged from 6.5 to 197.6 months, four patients in the conventional open cholecystectomy group encountered tumor recurrence, and one patient in the laparoscopic cholecystectomy group experienced distant tumor recurrence (p = 0.216). No local port-site tumor recurrence was identified in patients who underwent laparoscopic cholecystectomy. The overall 5-year survival rate in this series was 87.1%. A comparison of survival rates between the two groups demonstrated no significant difference (p = 0.340). Conclusion The laparoscopic cholecystectomy procedure did not adversely influence the prognosis of patients with early-stage gallbladder carcinomas. Furthermore, meticulous removal of gallbladders during laparoscopic surgery, in which early gallbladder carcinoma can be managed successfully using laparoscopic cholecystectomy, achieved a satisfactory surgical result and a low port-site tumor recurrence rate.     

Comparison of laparoscopic versus open cholecystectomy in patients with cardiac valve replacement

To evaluate the benefits and safety of laparoscopic cholecystectomy (LC) in patients with cardiac valve replacement (which frequently leads to cholelithiasis), 12 patients with cholelithiasis associated with cardiac valve replacement were studied. The patients were divided into two groups, of 6 patients each, according to the type of operation performed, open cholecystectomy (OC) or LC. The postoperative course was monitored with respect to laboratory data on postoperative days (POD) 1, 3, and 7. The mean duration of operation, blood loss, days to food resumption, length of hospital stay, and morbidity were compared between the two groups. Significant differences (P < 0.05) were found between the OC and LC groups in white blood cell counts on POD 1 (12 980 ± 3040/mm³ vs 8300 ± 1590/mm³), days to food resumption (2.7 ± 0.4 days vs 1.0 ± 0.7 days), and length of postoperative stay (15.8 ± 1.0 days vs 10.8 ± 1.6 days). There were no complications in the LC group, but 1 patient in the OC group had heart failure postoperatively. Our findings indicate the efficacy and safety of LC in patients with cardiac valve replacement. Received: August 14, 2000 / Accepted: December 22, 2000     

腹腔镜胆囊切除术与开腹胆囊切除术的临床特征及住院费用的对比

目的 对腹腔镜胆囊切除术的安全性，临床及经济价值作出评估。方法 对行ＬＣ的２７８例患者与开腹胆囊切除术的２３４例患者进行对比调查。结果 ＬＣ与ＯＣ具有相同的安全性；ＬＣ患者术后总的疼痛时间与严重疼痛时间，住院及出院后恢复工作的时间均明显短于ＯＣ患者；