急诊静脉溶栓治疗急性心肌梗塞疗效分析

目的探讨急诊静脉溶栓治疗急性心肌梗塞的疗效.方法 68例急性心肌梗塞患者分别予以尿激酶(UK)、链激酶(SK)和重组组织型纤溶酶原激活剂(rt-PA)溶栓治疗,根据冠脉再通率和病死率分析静脉溶栓治疗急性心肌梗塞的疗效.结果溶栓治疗后冠脉再通率、心功能明显改善;无一例死于溶栓后出血.结论急诊静脉溶栓治疗急性心肌梗塞疗效好、安全、可行.     

20例肺动脉栓塞诊断与治疗体会

目的；观察重组链激酶溶栓治疗急性大块及次大块型肺动脉栓塞的临床疗效；方法：对于明确诊断的急性大块及次大块肺动脉栓塞病例，即刻采用重组链激酶静脉溶栓，并观察其各项指标的变化。结果：本组20例急性肺动脉栓塞患者，抢救成功18例，死亡2例，成功率90％，治疗过程中未见严重出血事件。结论：重组链激酶溶栓治疗急性肺动脉栓塞成功率高，不良反应小。     

短期大剂量静脉输注尿激酶治疗急性心肌梗塞(附14例资料分析)

Fletcher A等于1959年首先应用链激酶治疗急性心肌梗塞,后因急性心肌梗塞与冠状动脉血栓的因果关系未定而使溶栓疗法搁置。近年资料证明约80％的急性心肌梗塞由冠状动脉内血栓形成所致。迅速恢复闭塞冠状动脉血流能及早供应缺血心肌足够的血液,缩小梗塞面积,改善泵功能,提高存活率。冠状动脉内输注链激酶治疗急性心肌梗塞疗效相当满意,但因必须冠状动脉内插管,不便普遍采用。本文旨在观察短期大剂量静脉输注尿激酶治疗急性心肌梗塞的临床效果。     

重组链激酶与尿激酶治疗急性下肢深静脉血栓疗效观察

目的：观察重组链激酶与尿激酶静脉溶栓治疗急性下肢静脉血栓的疗效及安全性。方法：60例急性下肢静脉血栓形成患者随机分为重组链激酶治疗组和尿激酶治疗组，采用溶栓疗法，观察临床疗效和不良反应。结果：一周后r-sk组和Uk组总有效率分别为90%，60%，两组疗效比较P＜0.05，无严重不良反应。结论：重组链激酶治疗急性下肢静脉血栓的疗效明显优于尿激酶，不良反应无明显差异。     

脑血栓形成血液流变性改变临床研究

目的：探讨脑血栓形成患者血液流变性的改变及溶栓疗法对血液流 变性的影响。方法：选择确诊为脑血栓形成的患者，于治疗前和溶栓治疗后分别测 定全血与血浆粘度等指标。结果：治疗前后患者血液流变学指标差异显著，治疗前 显著异常。结果：血流变性异常在脑血栓形成的发病中有重要作用，改善血流变性 和脑组织供血，减轻脑组织损伤。     

静脉溶栓后丁苯酞序贯治疗急性脑梗死的临床疗效及对神经功能的影响

目的：探究静脉溶栓后丁苯酞序贯治疗急性脑梗死的临床疗效及对神经功能的影响。方法：选取江西省赣州市宁都县人民医院于2020年5月至2021年12月收治的急性脑梗死者60例，开展简单随机化法分组处理，常规静脉溶栓方案者30例为对照组，静脉溶栓后予丁苯酞序贯治疗方案者30例为试验组，评定两组治疗效果、炎性因子水平、神经损伤标志物、血液流变学指标、不良反应。结果：治疗后，试验组治疗总有效率更高（P＜0.05）；治疗后两组炎性因子水平均低于治疗前，且试验组更低（P＜0.05）；治疗后两组丙二醛（MDA）、S100β、神经元特异性烯醇化酶（NSE）神经功能缺损标志物水平均低于治疗前，且试验组更低（P＜0.05）；治疗后两组血液流变学指标水平均低于治疗前，且试验组更低（P＜0.05）；两组不良反应发生率相比，差异无统计学意义（P＞0.05）。结论：急性脑梗死患者静脉溶栓后予丁苯酞序贯治疗，可提高治疗效果，改善患者的炎性因子、神经功能、血液流变学指标，且不会增加患者不良反应发生率，安全有效。     

杏丁注射液对肾病综合征血液流变学的影响

目的：观察杏丁注射液对肾病综合征（NS）血液流变学的影响。方法：将45例肾病综合征患者随机分为治疗组和对照组，治疗组在对照基础上加杏丁注射液治疗，观察治疗前后血液流变学指标的变化。结果：治疗组治疗后血液流变学各项指标均有明显改善，两组比较差异有统计学意义（P〈0．05）。结论：杏丁注射液能改善NS高凝状态，并下调NS各项血液流变学指标，协助基础治疗有一定意义。     

急性心肌梗塞静脉溶栓治疗后冠状动脉再通对左心功能的影响

目的：研究急性心肌梗塞（ＡＭＩ）静脉溶栓治疗后冠状动脉（冠脉）再通对左心功能的影响。方法：以２４例ＡＭＩ患者接受尿激酶（ＵＫ）静脉溶栓治疗为研究对象，再通组１４例，未通组１０例，于发病后３～４周在进行选择性冠脉造影或经皮穿刺冠脉内成形术（ＰＴＣＡ）的同时行Ｘ线左心室造影。结果：再通组射血分数（ＬＶＥＦ）明显高于未通组（Ｐ＜０．０５）；室壁异常活动积分未通组明显高于再通组（Ｐ＜０．０１），其中室壁瘤发生率再通组显著低于未通组，分别为７．１４％与３０．００％（Ｐ＜０．０５）。结论：监测ＬＶＥＦ及室壁局部运动是判断ＡＭＩ时溶栓治疗使梗塞区冠脉再通效果的有效指标；ＡＭＩ后及时有效的静脉溶栓治疗可缩小梗塞面积，改善左心功能，对改善ＡＭＩ患者的近期预后有十分重要的意义。     

急性心肌梗死溶栓治疗的护理

目的探讨重组链激酶治疗急性心肌梗死的效果及护理措施。方法将36例急性心肌梗死患者与重组链激酶溶栓治疗，总结溶栓期间的护理经验。结果通过精心的治疗和护理，36例患者中有22例冠状动脉再通，冠状动脉再通率达61％。结论急性心肌梗死早期静脉溶栓治疗简单易行，效果明显，及时正确的护理配合是十分重要的。     

急性心肌梗塞者应用链激酶溶栓的护理监护体会

静脉内“大量、短期、早用”链激酶治疗急性心肌梗塞，溶解冠状动脉内血栓，使闭塞的冠脉获得再通，缩小梗塞面积。不仅方法简便，而且疗效可靠。我科应用链激酶150万单位，一次静脉内溶栓2例，均获得成功。现将溶栓中的监护体会介绍如下：     

STAGGERS IN SHEEP IN PATAGONIA

After observations and experimental work both in the field and laboratory, the following conclusions seem justified. 1. Staggers is a non-infectious disorder affecting horses, cattle, and sheep. 2. The disease is characterized by weakness, muscular twitching, irregular movements of the head, stiffness of the limbs, and transient motor paralysis, accompanied with spastic spasms on excitement. There is also a derangement of vision and conjunctivitis. 3. The postmortem lesions are not characteristic. 4. We readily produced the disease by feeding susceptible sheep on a coarse tuft grass commonly known as coiron or pampa grass (Poa argentina). 5. The time required to produce definite symptoms by feeding the grass varied. Two animals developed typical staggers after two feedings; in another instance a period of 21 days of feeding was required. The average time for the production of unmistakable symptoms in our experiments was 10 days. 6. Many sheep recover from staggers spontaneously. A complete change of diet will usually effect a cure within 2 weeks. 7. Older .animals that have pastured for long periods on lands where the grass grows become tolerant and are rarely affected with staggers. 8. The grass is toxic to sheep at all seasons of the year. We fed late winter and early spring grass and grass in flower, and produced staggers in every instance. The young green grass is as toxic as any edible portion of the plant.     

TIMBER IN AUSTRALIA IN WARTIME

Fire history since 1850 was reconstructed by analysing tall wet eucalypt forest stands in the Warra long-term ecological research (LTER) site in southern Tasmania. Major fires occurred in 1898, 1906, 1914 and 1934. Fifty-seven percent of the forest has remained unburnt since 1850. Sixty percent of the forest burnt since 1850 occurs as mixed age stands, while 40 percent is pure regrowth. Ring counts of stumps of three veteran eucalypt trees indicated that the mature and oldgrowth forests of the Warra site represent a number of pre-1850 fires. One extant oldgrowth eucalypt stand was estimated to be over 450 years old. The common occurrence of multi-aged wet eucalypt stands has silvicultural implications where a management objective is to emulate pre-existing stand structures. While the fire history reported here is limited mainly to the period since 1850, it provides a good basis for understanding the current stand structures of the tall wet eucalypt forests of the Warra site. Such an understanding is essential to interpret results from current and planned ecological studies associated with the LTER program at Warra.     

BACTERIUM PNEUMOSINTES IN CLINICAL INFLUENZA IN NEW YORK CITY IN 1926

The presence of Bacterium pneumosintes has been demonstrated in nasopharyngeal washings from 2 patients in a sporadic outbreak of clinical influenza in New York City in March, 1926. 2 strains of bacteria morphologically similar to Bact. pneumosintes, but differing in certain cultural characters, and 2 other anaerobic filter-passing organisms were also isolated from the 9 patients examined. The blood serum of 16 among 17 persons convalescent from clinical influenza, and of 6 among 10 supposedly normal persons, agglutinated 1 or more strains of Bact. pneumosintes.     

RENAL TRANSPLANTATION IN DIABETES MELLITUS IN RATS

Immunoglobulins and complement are deposited in the glomerular mesangium of rats with progressive glomerulosclerosis secondary to chemically induced diabetes mellitus. Isotransplantation of a kidney from a rat diabetic for 6 mo into a normal recipient results within 2 mo in the disappearance of IgG, IgM, and β₁C from the mesangium and arrest or reversal of the light microscopic glomerular lesions. Kidneys isotransplanted from normal donors into diabetic rats developed mesangial matrix thickening and deposition of IgG, IgM) and β₁C in the mesangium. No glomerular changes occur upon transplantation of a normal kidney into a normal rat. These findings indicate that diabetic glomerular changes in the rat are reversible and are secondary to the diabetic state rather than to the inducing agent.