磁性附着体在覆盖全口义齿中的临床效果评价

目的 观察磁性附着体在覆盖全口义齿修复的临床治疗效果.方法 对16位患者采用磁性附着体覆盖全口义齿修复,并对义齿的固位咀嚼修复体使用情况的满意度以及义齿应用后出现的问题进行0.5～2.5年的随访.结果 磁性附着体可为覆盖义齿提供长期稳定的固位力且有助于基牙健康;16例义齿均正常使用,美观、咀嚼效能好,患者总体满意度高;应用磁力固位的覆盖全口义齿戴用后并发症少.结论 磁性附着体能明显改善覆盖全口义齿的固位及咀嚼效率,具有良好的远期效果.     

磁性附着体覆盖义齿的临床应用与效果评价

目的:评价磁性附着体覆盖义齿的临床应用效果.方法:用磁性附着体为31例患者制作覆盖义齿共39副,同时以19例常规总义:齿患者作为对照.对治疗效果和义齿的固位、咀嚼、修复体使用情况的满意度等进行调查.结果:患者对磁性附着体覆盖总义齿效果满意,患者总体满意度高;应用磁力固位的覆盖义齿戴用后并发症较少.结论:应用磁性附着体可显著改善覆盖义齿的功能,值得在临床推广应用.     

磁性附着体下颌全口种植覆盖义齿的临床应用

目的：观察磁性附着体下颌全口种植覆盖义齿的临床应用效果。方法：用MAGMAX2磁性附着体为21名患者制作下颌全口种植覆盖义齿，粘固磁体前后进行咀嚼效率和固位力测试，并做临床观察及问卷式主观感受的评价。结果：粘结磁体后固位力及咀嚼效率明显增加（P＜0．01），使用感觉也有改善。结论：磁附着体种植覆盖义齿的修复优于普通义齿，尤其对下颌条件不好的患者效果更为明显，值得推广。     

10例磁性附着体在全口覆盖义齿中的临床应用

目的:观察磁性附着体在覆盖义齿中的临床应用效果.方法:用Magfit磁性附着体为10例患者制作全口覆盖义齿共11副,在21颗基牙上安置磁性附着体.再以8例常规总义齿患者作为参照加以对比.采用分光光度法进行义齿咀嚼效率测试,并与对照组比较,同时观察基牙牙周状况.对10例以磁性附着体的患者进行患者主观满意度问卷调查.结果:患者对磁性附着体覆盖总义齿效果满意;粘固磁体后义齿咀嚼效率有明显的提升,并于戴牙3～6个月后达到稳定;基牙松动情况好转.结论:Magfit磁性附着覆盏义齿能显著提高义齿的固位力,改善咀嚼功能,能满足全口义齿行使各种口腔功能,值得推广应用.     

磁性体在活动义齿修复中的临床应用体会

目的：探讨磁性附着体在活动义齿修复中的临床应用效果。方法：对来本院就诊的9例牙列缺损患者,利用口内余留牙或残根残冠,采用Magfit血磁性附着体进行覆盖义齿进行修复,并对义齿的固位,咀嚼效率及患者自我感觉随访观察2年半。结果：9例患者戴用磁性附着体义齿后,随访观察期间均对其固位、稳定性及咀嚼功能表示满意。检查发现无牙龈炎症,基牙无继发龋、松动,义齿无折裂,根面板均未脱落。结论：磁性附着体在活动义齿修复中能显著提高义齿的稳定性,能够提高义齿的固位力和咀嚼效率,患者满意度高,并发症少,临床上可推广使用。     

Magfit磁性附着体在下颌全口覆盖义齿中的应用

目的:探讨磁性附着体的临床应用效果.方法:用Magfig EX磁性附着体为12名患者制作下颌全口覆盖义齿,粘固磁体前后进行咀嚼效率测试,并就义齿应用后出现的问题进行12～18月的随访观察.结果:粘固磁体后义齿的固位力及咀嚼效率明显提高,戴用义齿后并发症发生率较低.结论:Magfit磁性附着体能有效改善下颌全口覆盖义齿的固位,提高咀嚼效率,具有良好的临床应用效果.     

磁性附着体在义齿修复中的应用体会

[目的]观察磁性附着体用于全口覆盖义齿、可摘局部覆盖义齿及可摘局部义齿修复的效果。[方法]28例患者采用46个Magfit磁性附着体做根端覆盖义齿和冠外安置磁性附着体做可摘局部义齿修复,进行5年间定期复查。[结果]28例患者戴用义齿1年内均对固位、稳定性、咀嚼功能表示满意,检查基牙无病变。戴用1～5年后,陆续出现6例基牙疼痛,3例基牙牙龈炎,未发现继发龋、基牙松动、义齿折裂、根面板脱落等问题,所有义齿固位效果满意。[结论]磁性附着体能显著提高义齿的固位力及咀嚼效率（尤其对全口覆盖义齿）,舒适美观,并发症少,具有较好的应用前景。     

磁性附着体在覆盖义齿修复的临床应用研究

目的观察磁性附着体用于全口覆盖义齿和可摘局部覆盖义齿的修复的效果.方法24例患者采用46个Magfit磁性附着体做全口覆盖义齿修复,对义齿的固位、使用及基牙健康等情况进行2年的随访观察,对出现的问题及对策进行初步探讨.结果24例采用磁性附着体覆盖义齿的固位力,稳定性及咀嚼功能良好,基牙健康无龋坏.结论磁性附着体能显著提高义齿的固位力及咀嚼效率,缩短义齿的适应期,保护基牙的健康,美观效果好,是修复牙列缺失的好方法.     

磁性附着体种植覆盖义齿在无牙颌修复中的临床应用

目的评价磁性附着体种植覆盖义齿修复无牙颁的临床效果。方法对15例无牙颌患者行磁性附着体种植覆盖义齿修复,共使用39枚种植体,术后3～4月行磁性附着体种植覆盖义齿修复,每半年复诊．观察义齿使用情况,使用临床检查结合X线检查评估效果。结果39枚种植体术中及术后均未发生感染及神经损伤等并发症,修复前均达到骨结合;1例Replace种植体在覆盖义齿佩戴1．5年后脱落,其余种植体骨结合状况稳定;义齿固位效果良好．达到患者对美观和功能的要求;基台周围和义齿清洁度良好．疗效满意。结论磁性附着体种植覆盖义齿修复无牙颌可有效恢复咀嚼功能,改善患者容貌,临床效果可靠,制作简单．易于保持清洁．是一种值得推广的无牙颌修复方式。     

磁性附着体覆盖义齿在临床修复中的应用

目的：评价磁性附着体覆盖义齿在临床修复中的应用效果。方法：采用Magfit EX400W、Magfit EX600W磁性附着体为14例患者制作18件覆盖义齿，随访观察2年，评价义齿临床修复效果及患者满意度。结果：使用磁性附着体覆盖义齿临床修复效果满意，18件义齿除4例牙龈炎、1例磁体脱落外，未发现基牙明显松动、继发龋等。结论：磁性附着体覆盖义齿可有效地利用残冠残根，恢复患者口腔功能，提高咀嚼效率，在临床上有着良好的应用前景。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.