欧卡芙氟保护漆A型与多乐氟氟化钠护齿剂预防学龄前儿童龋病的效果对比

目的:比较欧卡芙氟保护漆A型与多乐氟氟化钠护齿剂预防学龄前儿童龋病的效果。方法:选取我市3岁儿童520名,随机分为3组,欧卡芙氟保护漆A型组(176名)和多乐氟氟化钠护齿剂组(174名)分别给予全口乳牙涂布该药物,空白对照组(170名)仅进行口腔卫生宣教。对比分析3组儿童干预前后患龋情况。结果:干预前3组儿童的患龋率及龋齿数差异均无统计学意义(P>0.05)。干预1年后,欧卡芙氟保护漆A型组患龋率、新增患龋人数均低于多乐氟氟化钠护齿剂组和空白对照组(P<0.05)。结论:两种药物均能防龋,欧卡芙氟保护漆A型防龋效果优于多乐氟氟化钠护齿剂。     

氟化钠护齿剂在预防上海市学龄前儿童龋齿中的效果评价

目的通过对上海市3岁学龄前儿童全口乳牙列涂布氟化钠护齿剂,实施群体性预防干预措施,分析评价氟化钠护齿剂预防儿童乳牙龋齿的效果。方法在上海市3个行政区内,随机选取1 905名符合涂氟防龋指征的3岁幼儿园儿童,随机分为3组,分别给予每年2次涂氟(试验A组)、每年1次涂氟(试验B组)和空白对照,对所有入组儿童进行口腔卫生指导,连续跟踪观察2年,记录患龋状况,采用Spss17.0软件进行统计学分析。结果 3组儿童的龋齿发病率和龋均值有显著性差异,实验组儿童龋齿发病率和龋均值显著低于对照组儿童,差异有统计学意义(P<0.05)。结论在学龄前儿童中应用氟化钠护齿剂能够有效降低乳牙龋齿发病率。     

氟化钠护齿剂与窝沟封闭剂用于防治学龄前儿童龋齿的效果评价

目的 探讨氟化钠护齿剂联合窝沟封闭预防学龄前儿童龋病的效果。方法 选取2014年1月—2014年9月西宁市口腔医院口腔中心实施窝沟封闭干预的200例学龄前儿童作为研究对象,采用随机数字表法分为联合组和对照组（各100例）,对照组采用窝沟封闭剂进行龋病预防,联合组采用氟化钠护齿剂联合窝沟封闭剂进行龋病预防。比较2组随访1年、2年的龋齿发生率,邻面龋发生率、龋均值、封闭剂的脱落情况。采用SPSS 16.0软件包进行t检验和χ²检验。结果 随访1年时,联合组和对照组的龋齿发生率、邻面龋发生率、龋均值均无显著差异（P>0.05）;随访2年时联合组的龋齿发生率、龋均值显著低于对照组（P<0.05）;联合组的邻面龋发生率与对照组相比,无显著差异（P>0.05）;联合组的窝沟封闭剂保留完好率显著高于对照组（P<0.05）;联合组和对照组的窝沟封闭剂部分脱落率、完全脱落率无显著差异（P>0.05）。结论 氟化钠护齿剂联合窝沟封闭预防学龄前儿童龋病较单纯使用窝沟封闭剂具有更好的防龋病效果。     

西安市2829名学龄前儿童乳牙龋患率调查

目的:了解西安市学龄前儿童乳牙龋病患病情况,便于更好地指导并开展龋病防治工作。方法:对西安市6所幼儿园2 829名学龄前儿童进行口腔检查。结果:2 829名受检儿童中,乳牙患龋儿童2 329名,患龋率82.33%,龋均4.4,乳磨牙窝沟封闭率为1.28%,性别间患龋率无差异,患龋率和龋均随年龄增高而上升,6岁患儿最高。结论:西安市学龄前儿童乳牙患龋率高于全国平均水平,应当引起足够重视,提高家长和社会的口腔健康意识,加大防治力度,保护儿童健康成长。     

氟保护漆乳牙防龋临床效果评价

目的　评价使用氟保护漆预防儿童乳牙龋病的效果。方法　对幼儿园 4～ 5岁儿童进行氟保护漆涂擦牙面 ,半年后重复涂擦 1次 ,1年后检查试验组和对照组乳牙患龋情况 ,并对试验前后进行比较。结果　试验后患龋率、龋均试验组明显低于对照组 ,两组之间存在显著性差异 (P <0 .0 1) ;试验组新增龋病发病率、新增乳牙龋均明显低于对照组。发病率两组之间存在显著性差异 (P <0 .0 1)。结论　氟保护漆对儿童乳牙龋病的预防是有效的。     

氟化钠滴剂预防儿童乳牙龋齿的2年临床效果评价

目的　研究氟化钠滴剂对儿童乳牙龋病的预防作用。方法　在成都市13所幼儿园3~4岁儿童中随机抽 取1 200人,平均分为3组,每组400人。第1组(氟滴组)采用氟化钠滴剂点滴;第2组(含氟牙膏组)采用含氟牙膏 刷牙;第3组(对照组)未采用任何统一干预措施。对这3组儿童进行2年的乳牙龋病预防评价。结果　氟滴组第 1、2年的新增龋面均分别为1·35±0·57和1·85±0·57,含氟牙膏组第1、2年的新增龋面均分别为1·53±1·09和 2·75±1·33,对照组第1、2年的新增龋面均分别为2·19±1·12和4·73±2·17。统计分析表明,氟滴组和含氟牙膏组 的新增龋面均低于对照组,二者之间的差异有统计学意义;氟滴组和含氟牙膏组二者新增龋面均的差异无统计学 意义。结论　氟化钠滴剂预防儿童乳牙龋齿的效果明显。     

应用氟化泡沫预防幼儿龋齿的防龋效果观察

目的：抽样调查东西湖区儿童使用氟化泡沫预防龋齿的效果。方法：对东西湖区8所幼儿园进行随机抽样,实验组儿童采用氟化泡沫护齿,每年2次,对照组儿童不做任何处理,2年后观察两组儿童之间患龋率及新龋发生率。结果：2年后实验组患龋率及新龋发生率均低于对照组,差异有统计学意义。结论：氟化泡沫能有效预防学龄前儿童龋病发展。     

沈阳市5375名3～6岁学龄前儿童乳牙龋病流行病学调查分析

目的了解沈阳市学龄前儿童乳牙患龋状况,为龋病防治提供科学依据。方法按照第二次全国口腔健康流行病学调查的要求,对沈阳市53所幼儿园的5375名3～6岁学龄前儿童进行龋病检查,对患龋率和龋均等指标做调查统计,结果采用SPSS11.0统计软件包进行分析,包括t检验、单因素方差分析和χ2检验。结果学龄前儿童乳牙患龋率和龋均分别为71.29%和3.88,龋面均为5.56;随着年龄的增长,患龋率、龋均和龋面均逐渐增加,各年龄组之间均有显著性差异(P<0.05);上颌牙患龋率显著高于下颌牙(P<0.01)。龋齿主要为浅龋,咬合面和邻面龋占绝大多数。龋齿充填构成比为10.82%,随着年龄的增长,龋齿充填构成比逐渐增加。结论沈阳市学龄前儿童乳牙患龋率较高,充填率较低,应加强对学龄前儿童龋病的早期防治。     

济宁市学龄前儿童龋病发生相关因素的调查分析

目的研究影响学龄前儿童龋病发生的相关因素。方法对济宁市两城区8个幼儿园1 875名3～6岁学龄前儿童进行龋病检查,并对儿童家长进行问卷调查,调查内容包括儿童出生状况、喂养方式和父母患龋情况等。结果1 875名学龄前儿童中,121名为早产儿,1 754名为足月儿,早产儿和足月儿的患龋率差异有统计学意义（χ^2=20.16,P〈0.01）。1 125名儿童的家长在喂养时有加糖习惯,750名儿童的家长在喂养时无加糖习惯,喂养时加糖的儿童和喂养时不加糖的儿童患龋率的差异有统计学意义（χ^2=37.62,P〈0.01）。父母双方均患龋的儿童341名,父母单方患龋的儿童784名,父母双方均无龋的儿童750名。父母双方均患龋的儿童和父母单方患龋的儿童的乳牙患龋率差异有统计学意义（χ^2=4.77,P〈0.05）,父母双方均患龋的儿童和父母双方均无龋的儿童的乳牙患龋率差异有统计学意义（χ^2=45.79,P〈0.01）,父母单方患龋的儿童与父母双方均无龋的儿童的乳牙患龋率差异也有统计学意义（χ^2=17.79,P〈0.01）。结论出生状况、喂养方式、父母患龋情况与学龄前儿童乳牙患龋明显相关。     

上海市徐汇区学龄前儿童龋病状况调查

目的：了解上海市徐汇区学龄前儿童乳牙患龋状况,为龋病防治提供科学依据。方法：以上海市徐汇区75所公办幼儿园10401名3?6岁儿童为调查对象,按照第4次全国口腔健康流行病学调查诊断标准进行口腔检查,提取龋病情况资料,包括患龋率、龋均、龋齿充填率。采用SAS 9.4软件进行统计学分析。结果：10401名受检儿童中,最容易患龋的牙位为上颌乳中切牙和下颌乳磨牙。患龋率为46.62%（4849/10401）,龋均为2.14?3.34,龋齿充填率为15.87%（3529/22243）。随着年龄增长,儿童患龋率和龋均增加（P<0.05）。6岁年龄儿童的龋齿充填率最高（P<0.05）,不同性别的龋齿充填率无统计学差异（P>0.05）。结论：上海市徐汇区学龄前儿童乳牙患龋率较高,龋齿充填率较低,应加强对学龄前儿童龋病的早期防治。     

A 2-year report on caries prevention by fluoride varnishes in a community with fluoridated water

The benefit of semi-annual applications of sodium fluoride varnish (Duraphat) and silane fluoride varnish (Fluor Protector) was studied in 11-13 year-old children with life-long exposure to fluoridated drinking water (1-1.2 parts/10(6)). Annual clinical and radiographic examinations were made on 67 children in the Duraphat group and 71 children in the Fluor Protector group. Fluoride varnish was applied semi-annually using the half-mouth technique. At the end of 2 years, the mean overall DMFS-increments on the control side and test side of the Duraphat group were 5.0 and 3.8 (p less than 0.01), respectively, and of the Fluor Protector group 3.7 and 3.3 (NS). The caries reductions were 24% and 12%, respectively. Since there were no differences between initial mean DMFS scores of the groups, it was assumed that lower increments in the Fluor Protector group were due to Fluoride ions crossing the midline and providing protection on the control side as well. When increments in the Duraphat control side and the Fluor Protector test side were compared, the caries reduction of Fluor Protector was 35% (p less than 0.01). Fluoride varnishes provide additional benefit even when fluoride intake from drinking water is optimal.     

含氟涂料与含氟泡沫对儿童龋病预防效果的对比研究

目的比较含氟涂料和含氟泡沫对儿童乳牙龋病的预防效果,为在我国开展乳牙龋病防治工作提供理论依据。方法随机整群抽样的方法抽取2所幼儿园的3~4岁儿童共220名,进行口腔检查,记录患龋情况。随机将这些儿童分为含氟泡沫组和含氟涂料组,分别用氟泡沫和氟保护漆进行龋齿预防,每半年1次,2年共干预4次,每年进行口腔检查,比较2组基线后1年和2年的乳牙新生龋均、新生龋面均及龋齿发病率。结果含氟泡沫组干预1年及2年后新生龋面均分别为2.58±4.36、3.85±5.15;含氟涂料组干预1年及2年后新生龋面均分别为0.95±2.28、1.94±3.32,均显著低于含氟泡沫组(P<0.01)。结论含氟涂料对儿童龋病的预防效果优于含氟泡沫。     

Three-year report on caries prevention of using fluoride varnishes for caries risk children in a community with fluoridated water

The benefit of semiannual application of the sodium fluoride varnish Duraphat and the silane fluoride varnish Fluor Protection was studied in 11--13-year-old children with high caries activity and life-long exposure to fluoridated drinking water (1--1.2 parts/10(6)). Annual clinical and radiographic examinations were made of 62 children in the Duraphat group and 70 children in the Fluor Protector group. Fluoride varnish was applied semiannually using the half-mouth technique. After 3 years, for the Duraphat group mean total DMFS increments on the control side were 6.2 and on the test side 4.3 (P less than 0.001); for the Fluor Protector group the DMFS increments were 4.9 and 4.4, respectively (NS). The caries reductions were 30% and 11%. Since there were no differences between initial mean DMFS scores of the groups, it is possible that the increment in the Fluor Protector control side compared to the Duraphat control side was due to fluoride ions from Fluor Protector crossing the midline and providing protection on the control side as well. Therefore, we conclude that Duraphat proved effective, but definite conclusion of the effect of Fluor Protector cannot be made. Children with the highest DMFS increment on the control side (Duraphat) gained most from the applications.     

A 2-year report on caries prevention by fluoride varnishes in a community with fluoridated water

Abstract – The benefit of semi-annual applications of sodium fluoride varnish (Duraphat®) and silanc fluoride varnish (Fluor Protector®) was studied in 11-13-year-old children with life-long exposure to fluoridated drinking water (1–1.2 parts/ 10⁶). Annual clinical and radiograpic examinations were made on 67 children in the Duraphat group and 71 children in the Fluor Protcctor group. Floride varnish was applied semi-annually using the half-mouth tecnique. At the end of 2 years, the mean overall DMFS- increments on te control side and test side of the Duraphat group were 5.0 and 3.8 ( P 0.01), respectively, and of te Fluor Protector group 3.7 and 3.3 (NS). The caries redutions were 24%and 12%, respectively. Since there were no differences between initial mean DMFS scores of te groups, it was assumed that lower increments in the Fluor Protector group were due to fluoride ions crossing the midline and providing protectioon on the control side as well. When increments in the Duraphat control side and the Fluor Protector test side were compared, the caries reducation of Fluor Protector was 35% ( P <0.01). Fluoride varnishes provide additional benefit even when fluoride intake from drinking water is optimal.     

Three-year report on caries prevention using fluoride varnishes for caries risk children in a community with fluoridated water

Abstract – The Benifit of seminnual application of the sodium fluoride varnish Duraphat^(R) and the silane fluoride varnish Fluor Protector^(R) was studied in 11–13-year-old children with high caries activity and lifelong exposure to fluoridated drinking water (1–1.2 parts/10⁶). Annual clinical and radiographic examinations were made of 62 children in the Duraphat group and 70 children in the Fluor Protector group. Fluoride varnish was applied semiannually using the half-moth technique. After 3 years, for the Duraphat group mean total DMES increments on the control side were 6.2 and on the test side 4.3 ( P <0.001); for the Fluor Protector group the DMES increments were 4.9 and 4.4, respectively (NS). The caries reductions were 30% and 11%. Since ther were no differences between initial mean DMES scores of the groups, it is possible that the lower increment in the Fluor Protector control side compatred to the Duraphat control side was due to fluoride ions from Fluor Protector crossing the midline and providing protection on the control side as well. Therefore, we conclude that Duraphat proved effective, but definite conslusion of the effect of Fluor Protector cannot be made. Children with the highest DMES increment on the control side (duraphat) gained most from the applications.     

The Efficiency of Semiannual Silane Fluoride Varnish Applications: a Two-year Clinical Study in Preschool Children

Objective : The aim of this two-year community demonstration trial was to study the caries inhibitory effects of semiannual applications of a fluoride varnish in preschool children. Methods : Twenty-four public dental health clinics in the county of Halland, Sweden, with 5,137 preschool children, 4 and 5 years of age, were matched and equally allocated to a fluoride varnish group ( n =2,535) and a reference group ( n =2,602). The children in the fluoride varnish group were treated every six months with topical applications of a silane fluoride varnish, Fluor Protector (0.1% F), while no fluoride varnish was used in the reference group. Both groups received a basic preventive program at annual checkups consisting of dietary counseling and instructions to parents to brush their children's teeth at least once daily with fluoridated dentifrice. Caries data were collected by clinical examinations at baseline and after one and two years. Results : Caries prevalence at baseline did not differ significantly between the groups. After two years, the mean caries incidence was low and no statistical difference was found in the total number of carious and filled surfaces (dfs) between the two groups. However, the incidence of approximal lesions (dfsa) was significantly lower ( P <.05) in the fluoride varnish group than the reference group. Children in the fluoride varnish group with dfs scores of 1–4 and ≥5 at the start of the study exhibited a statistically significant ( P <.05) reduction in approximal caries incidence of 19 percent and 25 percent, respectively, when compared with the reference group. Conclusion : Preschool children 4 and 5 years of age with clinical caries who receive semiannual applications of a silane fluoride varnish containing 0.1 percent F experience a reduced incidence of approximal caries over two years.     

Fissure sealing of permanent first molars in children receiving a high standard of proaphylactic care

The efficiency of sealing the occlusal fissures of permanent first molars was studied in a group of patients 6-9 yr of age receiving a high standard of prophylactic care. Very soon after the eruption one of the teeth in a homomaxillary pair was sealed, and the contralateral was used for control. The control teeth were painted with a fluoride varnish (Duraphat) every 6 months during the trial. 210 sites in 121 children were sealed and followed for a mean observation period of 23 months. At the end of the study, the retention rate was 62.9%, the percentage of effectiveness 24.2%, and the net gain 7.1%. The dmft index (primary molars and canines) was recorded for each patient at the time sealing was performed. A relationship between the caries prevalence in the primary teeth and the susceptibility for fissure caries in the control teeth was found. Effectiveness and net gain was highest in the group of children with 3-6 dmft.     

Fluoride varnish efficacy in preventing early childhood caries

To determine the efficacy of fluoride varnish (5% NaF, Duraphat, Colgate) added to caregiver counseling to prevent early childhood caries, we conducted a two-year randomized, dental-examiner-masked clinical trial. Initially, 376 caries-free children, from low-income Chinese or Hispanic San Francisco families, were enrolled (mean age +/- standard deviation, 1.8 +/- 0.6 yrs). All families received counseling, and children were randomized to the following groups: no fluoride varnish, fluoride varnish once/year, or fluoride varnish twice/year. An unexpected protocol deviation resulted in some children receiving less active fluoride varnish than assigned. Intent-to-treat analyses showed a fluoride varnish protective effect in caries incidence, p < 0.01. Analyzing the number of actual, active fluoride varnish applications received resulted in a dose-response effect, p < 0.01. Caries incidence was higher for 'counseling only' vs. 'counseling + fluoride varnish assigned once/year' (OR = 2.20, 95% CI 1.19-4.08) and 'twice/year' (OR = 3.77, 95% CI 1.88-7.58). No related adverse events were reported. Fluoride varnish added to caregiver counseling is efficacious in reducing early childhood caries incidence.