Processes linking socioeconomic disadvantage and neural correlates of cognitive control in adolescence

Socioeconomic status (SES) is broadly associated with self-regulatory abilities across childhood and adolescence. However, there is limited understanding of the mechanisms underlying this association, especially during adolescence when individuals are particularly sensitive to environmental influences. The current study tested perceived stress, household chaos, parent cognitive control, and parent-adolescent relationship quality as potential proximal mediators of the association between family SES and neural correlates of cognitive control. A sample of 167 adolescents and their primary caregivers participated in a longitudinal study across four years. SES was indexed by caregivers’ education and income-to-needs ratio at Time 1. At Time 2, adolescents reported on their perceived stress, household chaos, and relationship with parents, and parents completed a cognitive control task. Two years later, adolescents completed the same cognitive control task while blood-oxygenation-level-dependent (BOLD) response was monitored with functional magnetic resonance imaging (fMRI). A parallel mediation model indicated that parent cognitive control, but not other proximal factors, explained the relation between SES and adolescents’ activation in the middle frontal gyrus during a cognitive control task. The results suggest potential targets for intervention and prevention efforts that may positively alter neurocognitive outcomes related to socioeconomic disadvantage.     

Developmental trajectories of the socioeconomic status of occupational aspirations during adolescence

IntroductionProminent theories of career development suggest age-related changes in adolescents' occupational aspirations. However, little is known about how exactly and to what extent, adolescents' aspirations change, particularly regarding the socioeconomic status (SES) of aspired occupations. We aim at extending our knowledge of the developmental trajectories of the SES of occupational aspirations and potential gender differences in those trajectories.MethodsWe used longitudinal data from the German National Educational Panel Study (NEPS) consisting of a large and representative sample of secondary school students (N = 5,964, 50% females) from Grades 8 to 10 (age 14–16). Data were collected via a paper and pencil survey which was carried out in classrooms.ResultsOur analysis of a latent growth curve model revealed that adolescents experienced small increases in the SES of occupational aspirations from Grades 8 to 10. Multi-group models reveal that females initially aspired to higher-SES occupations and their aspirations exhibited larger growth over time compared to males.ConclusionsOur findings are in line with those from other countries but not with all, indicating some cross-cultural variabilities. Within cultures, the developmental trajectories of the SES of occupational aspirations seem to be similar across age-cohorts in the last 30 years. Despite women aspire to higher-SES occupations during adolescence, they often obtain lower-SES occupations than men in adulthood. Future research is needed to better understand the link between gender differences in the SES of occupational aspirations in adolescence and gender differences in the SES of occupational attainment in adulthood.     

The interplay of parental monitoring and socioeconomic status in predicting minor delinquency between and within adolescents

This six-wave multi-informant longitudinal study on Dutch adolescents (N = 824; age 12–18) examined the interplay of socioeconomic status with parental monitoring in predicting minor delinquency. Fixed-effects negative binomial regression analyses revealed that this interplay is different within adolescents across time than between adolescents. Between individuals, parental solicitation and control were not significantly associated with delinquency after controlling for SES: Adolescents whose parents exercised more monitoring did not offend less than others. Within individuals, higher levels of parental control were unexpectedly associated with more delinquency, but this relation was dependent on SES: Low-SES adolescents, but not high-SES adolescents, offended more during periods in which their parents exercised more control than during other periods with less control. In contrast to earlier work, this finding suggests that monitoring could be least effective when needed most. Low-SES parents might not use monitoring effectively and become overcontrolling when their child goes astray.     

Neurodevelopmental shifts in learned value transfer on cognitive control during adolescence

Value-associated cues in the environment often enhance subsequent goal-directed behaviors in adults, a phenomenon supported by the integration of motivational and cognitive neural systems. Given that the interactions among these systems change throughout adolescence, we tested when the beneficial effects of value associations on subsequent cognitive control performance emerge during adolescence. Participants (N = 81) aged 13–20 completed a reinforcement learning task with four cue-incentive pairings that could yield high gain, low gain, high loss, or low loss outcomes. Next, participants completed a Go/NoGo task during fMRI where the NoGo targets comprised the previously learned cues, which tested how prior value associations influence cognitive control performance. Improved accuracy for previously learned high gain relative to low gain cues emerged with age. Older adolescents exhibited enhanced recruitment of the dorsal striatum and ventrolateral prefrontal cortex during cognitive control execution to previously learned high gain relative to low gain cues. Older adolescents also expressed increased coupling between the dorsal striatum and dorsolateral prefrontal cortex for high gain cues, whereas younger adolescents expressed increased coupling between the striatum and ventromedial prefrontal cortex. These findings reveal that learned high value cue-incentive associations enhance cognitive control in late adolescence in parallel with value-selective recruitment of corticostriatal systems.     

Sleep and development in adolescence in the context of socioeconomic disadvantage

IntroductionSleep problems are associated with negative developmental outcomes in youth, and identification of vulnerability and protective factors is needed to explicate for whom and under which conditions adolescents may be most at risk. Towards this end, we examined socio-economic status (SES) as a moderator of associations between multiple sleep parameters and adolescents’ socio-emotional adjustment and cognitive functioning.MethodsParticipants were 272 adolescents (M age = 17.3 years; 49% girls) and their parents, residing in the Southeastern U.S.A. The sample was socioeconomically diverse and included 41% Black/African American and 59% White/European American youth. Using a cross-sectional design, adolescents' sleep was assessed with actigraphy (total sleep minutes; efficiency indicated by % of time asleep from sleep onset to wake time) and self-reports of sleep quality (sleep-wake problems). Mothers reported on youths’ internalizing and externalizing symptoms, and cognitive functioning was assessed with a standardized test battery.ResultsModeration effects were found and illustrated that, for youth from families with lower SES, shorter and less efficient sleep and subjective sleep problems were associated with higher levels of internalizing and externalizing symptoms as well as lower cognitive performance. Conversely, longer and better-quality sleep protected against socio-emotional and cognitive difficulties otherwise observed for socioeconomically disadvantaged youth. Fewer relations between sleep and adjustment emerged for adolescents from families with higher SES.ConclusionsResults reinforce a growing literature indicating that the relation between sleep and adjustment is stronger for youth from families with lower SES, who may especially benefit from better sleep.     

Neural cognitive control moderates the longitudinal link between hedonia and substance use across adolescence

Hedonic dysregulation is evident in addiction and substance use disorders, but it is not clearly understood how hedonic processes may interact with brain development related to cognitive control to influence risky decision making and substance use during adolescence. The present study used prospective longitudinal data to clarify the role of cognitive control in the link between hedonic experiences and the development of substance use during adolescence. Participants included 167 adolescents (53% male) assessed at four time points, annually. Adolescents participated in a functional magnetic resonance imaging (fMRI) session where blood-oxygen level dependent (BOLD) response was monitored during the Multi-Source- Interference Task to assess cognitive control. Substance use and hedonia were assessed using self-report. A two-group growth curve model of substance use with hedonia as a time-varying covariate indicated that higher levels of hedonia predicted higher substance use, but only in adolescents with higher activation in the frontoparietal regions and in the rostral anterior cingulate cortex during cognitive control. Results elucidate the moderating effects of neural cognitive control on associations between hedonia and adolescent substance use, suggesting that lower cognitive control functioning in the brain may exacerbate risk for substance use promoted by hedonia.     

Parental concerns,socioeconomic status,and the risk of autism spectrum conditions in a population-based study

A total number of 11,635 screening packs were distributed to 5–10 year-old children in 136 schools in Cambridgeshire to investigate the associations between levels of parental concern (none/minor/strong), socioeconomic status and the risk of having Autism Spectrum Conditions (ASC). The variables for investigating associations and possible confounders were extracted for analysis, including parental concern question score, SES, age of the child, sex, maternal age at birth, paternal age at birth, mother's age of leaving education, father's age of leaving education, birth order and the number of children in the family. The SES, age of the child, sex and mother's age at leaving education were associated with parental concern. Parents with higher SES reported higher levels of concern (Chi-square = 11.8; p = 0.02). However, a higher SES was not associated with the risk of having ASC (p = 0.50). After adjusting for potential confounders, the odds of children meeting ASC criteria whose parents had reported strong parental concern were 8.5 times (odds ratio: 8.5; 95%CI: 4.5, 16.2; p < 0.001) the odds of children having ASC whose parents reported minor concern. No child met ASC criteria where parents expressed no concerns. Parents with higher social class express more concerns than those from lower social classes. However, the concerns reported by parents in higher SES did not appear to be specific for ASC as there was no relationship between ASC and SES.     

The effect of physical activity on depression in adolescence and emerging adulthood: A growth-curve analysis

This study examined the influence of physical activity on the trajectory of depression from adolescence through emerging adulthood (EA). Using data from the National Longitudinal Study of Adolescent Health (Waves I to IV), latent growth curve modeling was performed to assess how physical activity and gender influenced depression across adolescence and EA. Higher levels of physical activity in mid-adolescence were associated with lower levels of depression during mid-adolescence and slower inclines and declines in depression over time. Boys had lower levels of depression in mid-adolescence and slower inclines and declines in depression over time compared to girls. Findings provide evidence that current theories on understanding depression and mental health prevention programs may be enhanced by the inclusion of physical activity.     

Dissociation of preparatory attention and response monitoring maturation during adolescence

ObjectiveSubstantial brain development occurs during adolescence providing the foundation for functional advancement from stimulus-bound “bottom-up” to more mature executive-driven “top-down” processing strategies. The objective was to assess development of EEG markers of these strategies and their role in both preparatory attention (contingent negative variation, CNV) and response monitoring (Error Related Negativity, ERN, and Correct Related Negativity, CRN).MethodsCNV, ERN and CRN were assessed in 38 adolescents (18 girls), age 11–18 years, using a variation of a letter discrimination task.ResultsAccuracy increased with age and developmental stage. Younger adolescents used a posterior attention network involved in inhibiting irrelevant information. Activity in this juvenile network, as indexed by a posteriorly-biased CNV and CRN decreased with age and advancing pubertal development. Although enhanced frontal CNV, known to be predictive of accuracy in adults, was not detected even in the older adolescents, top-down medial frontal response monitoring processes (ERN) showed evidence of development within the age-range studied.ConclusionsThe data revealed a dissociation of developmental progress, marked by relatively delayed onset of frontal preparatory attention relative to error monitoring.SignificanceThis dissociation may render adolescents vulnerable to excessive risk-taking and disinhibited behavior imposed by asynchronous development of component cognitive control processes.     

Testing the adolescent social reorientation model during self and other evaluation using hierarchical growth curve modeling with parcellated fMRI data

Adolescence is characterized as a period when relationships and experiences shift toward peers. The social reorientation model of adolescence posits this shift is driven by neurobiological changes that increase the salience of social information related to peer integration and acceptance. Although influential, this model has rarely been subjected to tests that could falsify it, or studied in longitudinal samples assessing within-person development. We focused on two phenomena that are highly salient and dynamic during adolescence—social status and self-perception—and examined longitudinal changes in neural responses during a self/other evaluation task. We expected status-related social information to uniquely increase across adolescence in social brain regions. Despite using hierarchical growth curve modeling with parcellated whole-brain data to increase power to detect developmental effects, we didn’t find evidence in support of this hypothesis. Social brain regions showed increased responsivity across adolescence, but this trajectory was not unique to status-related information. Additionally, brain regions associated with self-focused cognition showed heightened responses during self-evaluation in the transition to mid-adolescence, especially for status-related information. These results qualify existing models of adolescent social reorientation and highlight the multifaceted changes in self and social development that could be leveraged in novel ways to support adolescent health and well-being.     

Electrophysiological and behavioral indices of cognitive conflict processing across adolescence

Cognitive control enables goal-oriented adaptation to a fast-changing environment and has a protracted development spanning into young adulthood. The neurocognitive processes underlying this development are poorly understood. In a cross-sectional sample of participants 8–19 years old (n = 108), we used blind source separation of EEG data recorded in a Flanker task to derive electrophysiological measures of attention and conflict processing, including a N2-like frontal negative component and a P3-like parietal positive component. Outside the recording session, we examined multiple behavioral measures of interference control derived from the Flanker, Stroop, and Anti-saccade tasks. We found a positive association between age and P3 amplitude, but no relationship between age and N2 amplitude. A stronger N2 was age-independently related to better performance on Stroop and Anti-saccade measures of interference control. A Gratton effect was found on the Flanker task, with slower reaction times on current congruent and better accuracy on current incongruent trials when preceded by incongruent as opposed to congruent trials. The Gratton effect on accuracy was positively associated with age. Together, the findings suggest a multifaceted developmental pattern of the neurocognitive processes involved in conflict processing across adolescence, with a more protracted development of the P3 compared to the N2.     

Longitudinal associations among family environment,neural cognitive control,and social competence among adolescents

During adolescence, prefrontal cortex regions, important in cognitive control, undergo maturation to adapt to changing environmental demands. Ways through which social-ecological factors contribute to adolescent neural cognitive control have not been thoroughly examined. We hypothesize that household chaos is a context that may modulate the associations among parental control, adolescent neural cognitive control, and developmental changes in social competence. The sample involved 167 adolescents (ages 13–14 at Time 1, 53% male). Parental control and household chaos were measured using adolescents’ questionnaire data, and cognitive control was assessed via behavioral performance and brain imaging at Time 1. Adolescent social competence was reported by adolescents at Time 1 and at Time 2 (one year later). Structural equation modeling analyses indicated that higher parental control predicted better neural cognitive control only among adolescents living in low-chaos households. The association between poor neural cognitive control at Time 1 and social competence at Time 2 (after controlling for social competence at Time 1) was significant only among adolescents living in high-chaos households. Household chaos may undermine the positive association of parental control with adolescent neural cognitive control and exacerbate the detrimental association of poor neural cognitive control with disrupted social competence development.     

Trajectories of prosocial behaviors conducive to civic outcomes during the transition to adulthood: The predictive role of family dynamics

The current study explored the prediction of civic engagement by diverse trajectories of prosocial behaviors as well family dynamics (i.e., filial self-efficacy and relational parent–child support) across four times of assessment (from age 16–17 to age 22–23) during the transition to adulthood. Three different trajectories of prosocial behaviors were identified for 686 Italian youths: high-increasing (18%), medium-stable (48%), and low-stable (34%). An increasing pattern of change in prosocial behaviors was predicted by filial self-efficacy at age 16–17, which in turn mediated longitudinal relations to civic engagement and civic values at age 22–23. Results highlighted that during the transition to adulthood youths' beliefs about their ability to negotiate with their parents without losing autonomy and relatedness are relevant in promoting prosocial behaviors and civic involvement, especially in the context of Mediterranean countries.     

Neighborhood disadvantage and longitudinal brain-predicted-age trajectory during adolescence

Neighborhood disadvantage has consistently been linked to alterations in brain structure; however, positive environmental (e.g., positive parenting) and psychological factors (e.g., temperament) may buffer these effects. We aimed to investigate associations between neighborhood disadvantage and deviations from typical neurodevelopmental trajectories during adolescence, and examine the moderating role of positive parenting and temperamental effortful control (EC). Using a large dataset (n = 1313), a normative model of brain morphology was established, which was then used to predict the age of youth from a longitudinal dataset (n = 166, three time-points at age 12, 16, and 19). Using linear mixed models, we investigated whether trajectories of the difference between brain-predicted-age and chronological age (brainAGE) were associated with neighborhood disadvantage, and whether positive parenting (positive behavior during a problem-solving task) and EC moderated these associations. We found that neighborhood disadvantage was associated with positive brainAGE during early adolescence and a deceleration (decreasing brainAGE) thereafter. EC moderated this association such that in disadvantaged adolescents, low EC was associated with delayed development (negative brainAGE) during late adolescence. Findings provide evidence for complex associations between environmental and psychological factors, and brain maturation. They suggest that neighborhood disadvantage may have long-term effects on neurodevelopment during adolescence, but high EC could buffer these effects.     

Externalizing and internalizing behaviours in adolescence,and the importance of parental behavioural and psychological control practices

The aims of the present study were to explore the impact of parental characteristics (behavioural control and psychological control) on adolescents' expression of externalizing and internalizing behaviours. To address the aim of the study, participants completed quantitative measures; the study included 538 adolescents and their mothers and fathers. Overall, 513 mothers and 464 fathers participated in the study. Adolescents completed the Children's Report on Parent Behaviour Inventory (CRPBI), while parents completed the Child Behaviour Checklist – Parent Report (Short Form; CBCL). Results of the study showed that only maternal and paternal psychological control predicted externalizing and internalizing behaviours. The conclusions have practical applications, as they can provide novel approaches in parent training programmes. Furthermore, results are discussed in relation to the connection with earlier studies and the theoretical contribution.     

Brief report: Affluence and college alcohol problems: The relevance of parent- and child-reported indicators of socioeconomic status

A mediational model predicting alcohol problems was tested in a sample of college students (n = 130) and their parents (n = 115). The indirect effect of substance-use coping and the age of onset of alcohol use were examined in the relationship between socioeconomic status (SES) and alcohol problems. Findings indicated that parent-reported SES was associated with increased alcohol problems; the age of onset of alcohol use partially mediated this relationship. Substance-use coping was not a significant mediator in the model. Student-reported SES was not associated with alcohol problems. Implications for examining social status in relation to college drinking behaviors are discussed.     

The socioeconomic status of children with epilepsy in Zambia: implications for long-term health and well-being

Epilepsy is a highly stigmatized disorder in Zambia. Studies indicate that adults with epilepsy in many regions have significantly lower socioeconomic status (SES) than their peers. We conducted a case–control study of Zambian children with epilepsy (CWE) to assess their SES. Ninety-eight pairs of children were recruited (n = 196); their mean age was 10.8 years, and 59.7% were male. The comparison group’s medical conditions included asthma (54.0%), rheumatic heart disease (26.6%), type 1 diabetes (14.2%), and hypertension (5.2%). Compared with children with nonstigmatized chronic medical conditions, CWE have fewer educational opportunities, more environmental hazards, and poorer food quality and security (all P’s < 0.05). This deprivation may be related to lost maternal income for mothers who deferred employment so they could remain at home to care for their children. This early deprivation has long-term implications for health and well-being. Health care workers and child advocates need to be aware of the circumstances facing CWE in this region.     

The effect of social feedback from peers on adolescent cognitive control

IntroductionSocial feedback can influence cognitive control during adolescence, particularly if provided by peers. The main aim of this study was to investigate if feedback given by liked or disliked peers differentially influenced adolescents' cognitive control. The second aim was to investigate if these effects could be linked to the participants’ social embeddedness in their classroom.MethodsA personalized incentive go/no-go task was administered to 45 early adolescents (M = 11.6 years, 25 male) and 68 late adolescents (M = 16.7, 38 male) in the Netherlands. Feedback was given after no-go trials in two social feedback conditions (displaying a picture of a real liked or disliked classmate) and in a non-social control condition.ResultsPerformance on the task significantly improved with age. We found no differences between conditions in cognitive control, as measured by d-prime. However, analysis of task speed revealed slower reaction times during the liked peer condition as compared to the disliked peer and the control condition, potentially suggesting that participants responded more cautiously, or alternatively that participants were more distracted. These effects did not differ between age groups. Participants’ differences in task performance were not reflected in their social embeddedness in the classroom.ConclusionsThis study shows that the same kind of social feedback can have different effects on adolescent behaviour depending on the peer delivering the feedback. It demonstrates the importance of studying the effects of real life social environments to better understand and utilize their impact on adolescent development.     

Developmental trajectories of cortical thickness by functional brain network: The roles of pubertal timing and socioeconomic status

The human cerebral cortex undergoes considerable changes during development, with cortical maturation patterns reflecting regional heterogeneity that generally progresses in a posterior-to-anterior fashion. However, the organizing principles that govern cortical development remain unclear. In the current study, we characterized age-related differences in cortical thickness (CT) as a function of sex, pubertal timing, and two dissociable indices of socioeconomic status (i.e., income-to-needs and maternal education) in the context of functional brain network organization, using a cross-sectional sample (n = 789) diverse in race, ethnicity, and socioeconomic status from the Lifespan Human Connectome Project in Development (HCP-D). We found that CT generally followed a linear decline from 5 to 21 years of age, except for three functional networks that displayed nonlinear trajectories. We found no main effect of sex or age by sex interaction for any network. Earlier pubertal timing was associated with reduced mean CT and CT in seven networks. We also found a significant age by maternal education interaction for mean CT across cortex and CT in the dorsal attention network, where higher levels of maternal education were associated with steeper age-related decreases in CT. Taken together, our results suggest that these biological and environmental variations may impact the emerging functional connectome.