Increased knee loading in stair ambulation in patients dissatisfied with their total knee replacement

BackgroundTotal knee replacement patients have shown reductions in knee flexion range of motion, knee extensor moments, and gait speed during stair ascent and stair descent. However, it is unknown how patients dissatisfied with their total knee replacement differ from those who are satisfied during more difficult activities such as stair negotiation. Therefore, the purpose of this study was to compare knee biomechanics of patients who are dissatisfied with their joint replacement to those who are satisfied and healthy participants during stair negotiation.MethodsNine dissatisfied, fifteen satisfied patients and fifteen healthy participants participated, completing stair ascent and descent trials on an instrumented staircase. A 2 × 3 ANOVA was used to analyze biomechanical differences between groups and limbs during both activities.FindingsThe dissatisfied group showed reduced 2nd peak vertical GRF (P ≤ 0.0040) and loading-response knee extension moments (P ≤ 0.0041) in their operated limb compared to their non-operated limb and to satisfied and healthy groups during stair ascent. First peak vertical GRF (P < 0.0088) and both loading-response (P < 0.0117) and push-off abduction moments (P < 0.0028) showed reduced values in operated limbs compared to non-operated limbs for all groups. During stair descent, the dissatisfied group showed reduced loading-response and push-off knee extension moments (P ≤ 0.006) in their operated limb compared to their non-operated limb and the healthy group. The loading-response knee extension (P < 0.0379) and abduction moments (P ≤ 0.0048) were also reduced in the dissatisfied group compared to the satisfied group.InterpretationPatients who were dissatisfied showed asymmetrical loading of the knees in conjunction, which may have contributed to their dissatisfaction.     

Tibial rotation in anterior cruciate ligament reconstructed knees during single limb hop and drop landings

Background

Alterations in knee joint kinematics have been suggested as a potential mechanism that influences the development of osteoarthritis of the knee after anterior cruciate ligament reconstruction. Whilst previous work has shown changes in internal–external tibial rotation during level walking, many patients aim to return to high impact activities following surgery. This study examined tibial rotation during single limb hop and drop landings in anterior cruciate ligament reconstructed knees compared to a control group, and also evaluated the influence of graft type (hamstring or patellar tendon).

Methods

In 48 participants (17 patellar tendon graft, 18 hamstring graft and 13 controls) internal–external rotation was measured during single limb hop and drop landings in a gait laboratory at mean of 10 months after surgery.

Findings

There was no difference between the two graft types and both patient groups had less internal rotation when compared to the control group. For 60% of patients, internal rotation values were at least 5°  less than the control group mean.

Interpretation

Anterior cruciate ligament reconstructed knees with both hamstring tendon and patellar tendon grafts show altered rotational kinematic patterns during high impact dynamic load activities.     

Delayed onset of quadriceps activity and altered knee joint kinematics during stair stepping in individuals with knee osteoarthritis

OBJECTIVE: To determine if the electromyographic onset of vastus lateralis and kinematic knee joint motion in individuals with knee osteoarthritis (OA) differs from that of asymptomatic persons, during the task of stair stepping. DESIGN: Cross-sectional. SETTING: University laboratory in Australia. PARTICIPANTS: Twenty-five participants with symptomatic knee OA and 33 asymptomatic controls. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Surface electromyography to determine the onset of vastus lateralis activity. Two-dimensional kinematic analysis of sagittal plane knee motion during stance phase of stair ascent and descent. RESULTS: Participants with knee OA showed delayed onset of vastus lateralis activity during stair descent (P<.05) but not ascent. Both groups displayed a similar total range of knee motion. However, during stair descent, participants with OA had less knee flexion during early stance (P<.05) than controls. CONCLUSION: Individuals with knee OA display altered quadriceps function and knee joint kinematics during stair descent. These impairments may have implications for force attenuation across the knee joint and warrant future investigation.     

Pre- and postoperative in silico biomechanics in individuals with cam morphology during stair tasks

BackgroundOsteochondroplasty for cam femoroacetabular impingement is a common treatment to improve hip function and prevent joint degeneration. The purpose was to compare in-silico hip biomechanics during stair tasks in pre- and postoperative patients matched with healthy controls.MethodsTen symptomatic cam femoroacetabular impingement patients performed stair ascent and descent pre- and 2 years postoperatively. Patients were age, and body-mass-index matched to controls. Full-body kinematics and kinetics were computed and, muscle and hip contact forces were estimated using musculoskeletal modeling and static optimization. Stance-phases were time-normalized and compared using statistical non-parametric mapping.FindingsPreoperatives showed lower hip abduction than controls during stairs ascent (76–100%, P = .007). Pre- and postoperative showed lower hip external rotation compared to controls on stair ascent (Pre-op vs controls: 71–100%, P = .005; Post-op vs controls: 72–100%, P = .01) and stair descent (Pre-op vs controls: 0–62%, P = .001; Post-op vs controls: 0–60%, P = .001). Postoperatives showed lower iliacus force compared to preoperative (1–3%, P = .012) and control (3–6%, P = .008), and higher gluteus maximus and piriformis forces compared to controls during stair descent. Lower postoperative anterior hip contact force (0–7%, P = .004) during descent, and superior (33–35%, P = .018) during ascent compared to controls were observed. Postoperative contact forces were medialized compared to preoperative (0–2%, P = .011) and controls (1–2%, P = .016).InterpretationForcing participants to adhere to standardized step length/rise minimized sagittal kinematic differences between conditions and groups. Persistent reduced hip external rotation postoperatively and minor muscle force adaptations led to reduced superior hip contact force during stair ascent and reduced anterior and more medialized contact forces during stair descent.     

Mobile and fixed bearing total knee prosthesis functional comparison during stair climbing

OBJECTIVE: The purpose of this investigation is to determine the functional performance of the mobile bearing total knee replacement prosthesis as compared to the fixed bearing type total knee replacement prosthesis. DESIGN: Kinematics, kinetics, and electromyography data were gained from 10 patients with mobile bearing and 10 patients with a fixed bearing posterior stabilized Insall Burstein II total knee replacement during ascending and descending stairs. A control group of 10 normal subjects, matched by sex and age, was also analysed. BACKGROUND: No significant biomechanical differences in patients with different total knee replacement designs have been reported from level-walking studies. Slightly better performance of posterior retaining with respect to cruciate sacrificing total knee replacement designs have been claimed from stair climbing studies. Only one study has been conducted regarding mobile versus fixed bearing total knee replacement assessed by gait analysis. This study did not show any biomechanical differences between the two groups. METHODS: Motion analysis was used to quantify the knee kinematics, kinetics, and electromyography (right and left longissimus dorsi, gluteus medius, rectus femoris, biceps femoris, semitendinosus, gastrocnemius and tibialis anterior muscles) during stair ascent and descent. RESULTS: The mobile bearing group demonstrated a reduced knee extensor moment during stair climbing and descending, and a reduced knee adductor moment during stair climbing. When ascending stairs, most of the mobile bearing patients show a peak knee flexion and a peak knee flexion moment at the late stance phase during the double support period. This kinematic and kinetic pattern is absent in normal subject. Both mobile bearing and fixed bearing groups showed abnormal electromyography patterns in both descending and ascending. CONCLUSIONS: During stair climbing, the mobile bearing design demonstrates a different kinematic pattern to the fixed bearing total knee replacement. Lower limb compensatory mechanisms seemed to be adopted particularly by the mobile bearing patients during ascending stairs. RELEVANCE: Total knee replacement patient with mobile bearing design can feel excessive femoro-tibial motion during daily living activities such as stair climbing and descending. Proprioceptive control of this tibio-femoral translation is needed as demonstrated by the lower limb compensatory mechanism. This data suggest that antero-posterior constraint structures (ligamentous or mechanical) are important to obtain reproducible knee kinematics.     

External loading alters lower extremity kinetics,kinematics, and muscle activity in a distribution-specific manner during the transition from stair descent to level walking

BackgroundExcess body mass is thought to be a major cause of altered biomechanics in obesity, but the effects of body mass distribution in biomechanics during daily living tasks are unknown. The purpose of this study was to determine how increasing body mass centrally and peripherally affects lower extremity kinematics, kinetics, and muscle activation when transitioning from stair descent to level gait.MethodsFifteen normal weight volunteers descended a staircase at a self-selected pace under unloaded, centrally loaded, and peripherally loaded conditions. Spatial-temporal gait characteristics and lower extremity joint kinematics, kinetics, and mean electromyography amplitude were calculated using 3D motion analysis.FindingsBoth central and peripheral loading reduced gait velocity. Peripheral loading increased time spent in stance phase, increased step width, and reduced step length. At the hip joint, peripheral loading reduced peak hip extension and adduction angle. Conversely, central loading reduced peak hip flexor moment. Both central and peripheral loading increased peak knee flexion angle, but only peripheral loading increased peak knee extensor moment. Central and peripheral loading increased mean electromyography amplitude of the medial gastrocnemius, but only peripheral loading increased mean electromyography amplitude of the semitendinosus and the vastus medialis.InterpretationIncreasing mass centrally and peripherally differently affects spatial-temporal gait characteristics and lower extremity joint kinematics, kinetics, and electromyography when transitioning from stair descent to level gait. Body mass distribution may be an important factor for obesity-induced biomechanical alterations and should be considered when developing biomechanical models of obesity.     

CONSISTENCY OF DYNAMIC KNEE VALGUS KINEMATICS AND PAIN ACROSS FUNCTIONAL TASKS IN FEMALES WITH PATELLOFEMORAL PAIN: A CROSS-SECTIONAL STUDY

Background and Purpose:Dynamic knee valgus has been associated with patellofemoral pain (PFP) during high-level tasks, however, repeated lower-level stresses may be an alternative pain mechanism. The primary purpose of the current study was to examine the consistency of dynamic knee valgus and task-elicited pain demonstrated by females with PFP across four common functional tasks (stair ascent, stair descent, sit-to-stand, and stand-to-sit). A secondary purpose was to assess the correlation between the clinical test of single-limb squat and functional tasks.Hypothesis:Females with patellofemoral pain will demonstrate a positive relationship in magnitude of dynamic knee valgus and task-elicited pain across functional tasks. Individuals who demonstrated greater dynamic knee valgus and task-elicited pain during the clinical test of single-limb squat would demonstrate greater dynamic knee valgus and task elicited pain during stair ascent/descent and sit-to-stand/stand-to-sit tasks.Study Design:Cross-sectional study; secondary analysis of a feasibility intervention study.Methods:Twenty-three women with patellofemoral pain (age: 21.8 SD 3.7 years; BMI: 22.2 SD 2.0 kg/m²) participated. Three-dimensional kinematic data were captured during task completion. Hip and knee frontal and transverse plane angles at 45 ° of knee flexion, and pain using a visual analog scale, were assessed during single-limb squat, stair ascent/descent, and sit-to-stand. Pearson product-moment correlation coefficients were calculated to examine between-task relationships for each variable at the pre-intervention assessment.Results:Correlation coefficients between tasks ranged from 0.23-0.76 for hip frontal plane measures (7/10 significant relationships, p<0.02), 0.31-0.90 for hip transverse plane measures (7/10 significant, p<0.01), 0.87-0.95 for knee frontal plane measures (10/10 significant, p<0.01), and 0.54-0.86 for knee transverse plane measures (10/10 significant, p<0.01). Correlations spanned 0.59-0.85 for pain during tasks (10/10 significant, p<0.01).Conclusion:Females with patellofemoral pain demonstrated positive correlations in dynamic knee valgus kinematics and task-elicited pain across five tasks. Movement and pain during the clinical test of single-limb squat test also was correlated with movement and pain during the functional tasks of stair ascent/descent and sit-to-stand.Level of Evidence:Level 2b.     

Biomechanical compensations of the trunk and lower extremities during stepping tasks after unilateral transtibial amputation

BackgroundLower extremity movement compensations following transtibial amputation are well-documented and are likely influenced by trunk posture and movement. However, the biomechanical compensations of the trunk and lower extremities, especially during high-demand tasks such as step ascent and descent, remain unclear.MethodsKinematic and kinetic data were collected during step ascent and descent tasks for three groups of individuals: diabetic/transtibial amputation, diabetic, and healthy. An ANCOVA was used to compare peak trunk, hip and knee joint angles and moments in the sagittal and frontal planes between groups. Paired t-tests were used to compare peak joint angles and moments between amputated and intact limbs of the diabetic/transtibial amputation group.FindingsDuring step ascent and descent, the transtibial amputation group exhibited greater trunk forward flexion and lateral flexion compared to the other two groups (P < 0.016), which resulted in greater low back moments and asymmetric loading patterns in the lower extremity joints. The diabetic group exhibited similar knee joint loading patterns compared to the amputation group (P < 0.016), during step descent.InterpretationThis study highlights the biomechanical compensations of the trunk and lower extremities in individuals with dysvascular transtibial amputation, by identifying low back, hip, and knee joint moment patterns unique to transtibial amputation during stepping tasks. In addition, the results suggest that some movement compensations may be confounded by the presence of diabetes and precede limb amputation. The increased and asymmetrical loading patterns identified may predispose individuals with transtibial amputation to the development of secondary pain conditions, such as low back pain or osteoarthritis.     

Long-term gait biomechanics in level,uphill, and downhill conditions following anterior cruciate ligament reconstruction

BackgroundAltered gait biomechanics have been linked to post-traumatic knee osteoarthritis development following anterior cruciate ligament reconstruction surgery, but the persistence of aberrant gait biomechanics after the first year post-surgery is inconsistent in the literature. Gait biomechanics are typically evaluated on a level surface, but this task may not elucidate discrepancies in individuals further removed from surgery due to the simplicity of the task. Graded surfaces are common in real-world ambulation and may exacerbate aberrant gait biomechanics due to greater mechanical demands.MethodsForty-seven individuals post-anterior cruciate ligament reconstruction (4 ± 3 years post-surgery) and forty-seven uninjured controls completed gait analysis under level, uphill, and downhill conditions on an instrumented treadmill. Outcomes included knee flexion displacement and peak knee flexion angle, vertical ground reaction force, and knee extension and abduction moments.FindingsKnee extension moment and knee flexion displacement were lesser in the surgical limb compared to the contralateral during the downhill condition, with lesser knee flexion displacement also observed during the level condition. Additionally, knee extension moment was less symmetrical in the surgical group during both uphill and downhill conditions compared to controls. Knee flexion displacement was less symmetrical in the surgical group during both level and downhill conditions compared to controls.InterpretationGraded surfaces elucidate aberrant gait biomechanics in individuals more than 1 year post-anterior cruciate ligament reconstruction that are not apparent during level walking. These findings suggest that gait assessment on level surfaces may mask existing deficiencies, and warrant emphasizing ambulation of graded surfaces during anterior cruciate ligament rehabilitation.     

Alterations in joint kinematics during walking following hamstring and patellar tendon anterior cruciate ligament reconstruction surgery

Background

Previous research has shown that patients with anterior cruciate ligament reconstruction have altered movement patterns in the reconstructed knee during walking. In the sagittal plane, graft specific changes in knee joint motion have been reported between hamstring and patellar tendon anterior cruciate ligament reconstruction grafts. This study examined the secondary planes of movement during walking in anterior cruciate ligament reconstructed knees to evaluate the influences of graft type (hamstring or patellar tendon) and control condition (control group or contralateral knee).

Methods

In 54 participants (18 patellar tendon graft, 18 hamstring graft and 18 controls) varus–valgus and internal–external rotation was measured during level walking in a gait laboratory at mean of 10 months after surgery. All patients had undergone primary unilateral anterior cruciate ligament reconstruction within 12 months of injury.

Findings

For internal–external rotation there was no difference between the graft types and both patient groups had reduced internal rotation (an external rotation offset) and reduced internal rotation range when compared to the control group and contralateral knee. For 31 of 36 patients, internal rotation values were less than the control group mean. The hamstring group had reduced varus rotation compared to both the patellar tendon and control groups, but not when compared to the contralateral knee.

Interpretation

The results show that there are differences in tibial rotation during walking in anterior cruciate ligament reconstructed knees compared to both the contralateral knee and uninjured control group. These kinematic alterations may relate to the high incidence of knee osteoarthritis observed in this population over time. Reduced varus in the hamstring group may relate to the graft harvest.     

Knee joint moments during stair climbing of patients with anterior cruciate ligament deficiency

OBJECTIVE: To establish the gait adaptations of patients with anterior cruciate ligament deficiency during stair ascent. DESIGN: Joint kinematics and kinetics during stair climbing were measured in both knees of normal subjects and unilateral anterior cruciate ligament deficient patients. BACKGROUND: As there is limited research pertaining to activities other than level walking, the purpose of the current study was to elucidate the gait of patients with anterior cruciate ligament deficiency during stair climbing to determine the effects of the deficiency on knee joint motion and moments as compared with normal knee function. METHODS: A motion analysis system was used to measure and calculate kinematic and kinetic data for six normal subjects and nine patients with unilateral anterior cruciate ligament deficiency during stair ascent on a specially constructed staircase. Left and right leg data were analysed to reveal between-limb differences for each subject. RESULTS: Patients with anterior cruciate ligament deficiency displayed a significant (P < 0.05) reduction of up to 50% in peak knee flexion moments in their involved knee. In the present study where a step height of 15.5 cm was used, peak flexion moments in all subjects' limbs occurred at knee flexion angles of about 40 degrees during single limb support. CONCLUSION: The current study showed that most patients with an anterior cruciate deficient knee adapted their gait during stair ascent. RELEVANCE: As stair climbing is a common activity, its effect on gait is relevant to better understand appropriate treatment and management strategies of patients with anterior cruciate ligament deficient knees.     

Trunk and lower limb biomechanics during stair climbing in people with and without symptomatic femoroacetabular impingement

BackgroundFemoroacetabular impingement is a pathomechanical hip condition leading to pain and impaired physical function. It has been shown that those with femoroacetabular impingement exhibit altered gait characteristics during level walking and stair climbing, and decreased muscle force production during isometric muscle contractions. However, no studies to-date have looked at trunk kinematics or muscle activation during dynamic movements such as stair climbing in this patient population. The purpose of this study was to compare biomechanical outcomes (trunk and lower limb kinematics as well as lower limb kinetics and muscle activation) during stair climbing in those with and without symptomatic femoroacetabular impingement.MethodsTrunk, hip, knee and ankle kinematics, as well as hip, knee and ankle kinetics and muscle activity of nine lower limb muscles were collected during stair climbing for 20 people with clinical and radiographic femoroacetabular impingement and compared to 20 age- and sex-matched pain-free individuals.FindingsThose with femoroacetabular impingement ascended the stairs slower (effect size = 0.82), had significantly increased peak trunk forward flexion angles (effect size = 0.99) and external hip flexion moments (effect size = 0.94) and had decreased peak external knee flexion moments (effect size = 0.90) compared to the control group.InterpretationFindings from this study indicate that while those with and without femoroacetabular impingement exhibit many biomechanical similarities when ascending stairs, differences in trunk forward flexion and joint kinetics indicate some important differences. Further longitudinal research is required to elucidate the cause of these differences as well as the clinical relevance.     

Association of sensorimotor function with knee joint kinematics during locomotion in knee osteoarthritis

OBJECTIVE: To evaluate the relationship between quadriceps sensorimotor function (knee joint-position sense, quadriceps strength, and quadriceps onset of activity) and knee joint kinematics (knee flexion at initial contact and loading) during level walking and stair descent in a large cohort of 220 people with knee osteoarthritis. DESIGN: Cross-sectional correlational study. RESULTS: Joint-position sense correlated with knee flexion at initial contact during both tasks (r = -0.20 and -0.14, P <0.05). Strength correlated with peak loading response knee flexion during both tasks (r = 0.17 and 0.20, P < 0.05). Quadriceps onset correlated with knee flexion at initial contact during stair descent (r = 0.14, P < 0.05). Furthermore, differences in kinematic variables were observed when participants were divided into those with best and worst sensorimotor function. CONCLUSION: Impaired sensorimotor function as measured in this study is not strongly associated with altered knee joint kinematics observed in knee osteoarthritis patients during locomotion.     

Lower extremity kinetics during stair ambulation in patients with and without patellofemoral pain

Objective. To compare lower extremity kinetics during stair ascent and descent in subjects with and without patellofemoral pain.

Design. A cross-sectional study utilizing a control group.

Background. The patellofemoral joint reaction force (the resultant force between the quadriceps muscle force and patellar ligament force) increases with quadriceps force and knee flexion angle. Consequently, patients with patellofemoral pain may employ compensatory strategies to minimize pain and reduce patellofemoral joint reaction forces during activity.

Methods. 10 individuals with a diagnosis of patellofemoral pain and 10 individuals without pain participated. Subject groups were matched on sex, age, height, and body mass. Anthropometric data, three dimensional kinematics, and ground reaction forces were used to calculate lower extremity sagittal plane moments (inverse dynamics) while subjects ascended and descended stairs at a self-selected pace. Differences in kinetic variables between groups were assessed using 2×2 (group × stair condition) analysis of variance.

Results. Subjects with patellofemoral pain had decreased peak knee extensor moments during stair ascent and descent. There were no group differences in peak hip, ankle, or support moments, however, subjects with patellofemoral pain had decreased cadence (descent) compared to controls.

Conclusion. Subjects with patellofemoral pain had reduced peak knee extensor moments, suggesting that quadriceps avoidance was employed to reduce patellofemoral joint reaction forces. The lack of group differences in peak moments at the hip and ankle suggests that secondary compensation did not occur exclusively at the hip or ankle in this group of subjects with patellofemoral pain.Relevance statement

Because stair ambulation is often used to evaluate the reproducibility of symptoms and to identify abnormal movement patterns indicative of patellofemoral pain, knowledge of lower extremity mechanics during stair negotiation is necessary to better characterize compensatory behavior in this population.     

The use of a lateral wedge insole to reduce knee loading when ascending and descending stairs in medial knee osteoarthritis patients

Background

Stair climbing is a challenging task to the elderly being the task with the first complaint in patients with mild to moderate knee osteoarthritis. Stair climbing results in around six times more compressive load transmitted through the knee joint than walking on level ground. The purpose of this study was to assess whether lateral wedge insoles would reduce medial compartment knee loading when ascending and descending stairs in patients with medial knee osteoarthritis.

Methods

Eight patients with medial knee osteoarthritis were tested in random order with and without a pair of 5° off-the-shelf lateral wedge insoles for two separate activities (stair ascent and stair descent). Kinematic and kinetic data were collected for the lower extremity using a sixteen camera motion capture system and two force plates. Primary outcome measures were the external knee adduction moment and the knee adduction angular impulse.

Findings

During stair ascent and descent, lateral wedge insoles significantly (P < 0.05) reduced the 1st peak external knee adduction moment in early stance (ascent 6.8%, descent 8.4%), the trough in mid stance (ascent 13%, descent 10.7%), 2nd peak in the late stance (ascent 15%, descent 8.3%) and the knee adduction angular impulse compared to the control (standard shoe) with large effect sizes (0.75–0.95).

Interpretation

In this first study on stairs, lateral wedge insoles consistently reduced the overall magnitude of medial compartment loading during stair ascent and descent. Further research is needed to determine the relationship of this with clinical results when ascending and descending stairs with lateral wedge insoles.     

Clinical and biomechanical assessment of patella resurfacing in total knee arthroplasty

BACKGROUND: Currently there is a limited understanding of the factors influencing range of motion by comparing patellar resurfacing vs non-resurfacing in total knee arthroplasty during activities of daily living. A recent meta-analysis of patellar replacement confirms better outcome with patella resurfacing; however, the result can be influenced by many other factors, such as: component design, surgeon experience, and technical aspects of the surgery. This study compares the biomechanics of the knee in patients after total knee arthroplasty with and without patellar resurfacing during stair climbing. METHODS: Forty-seven patients with total knee arthroplasty were assessed at the mean follow-up of 24 months. In all of them a posterior stabilised fixed bearing prosthesis (Optetrak PS, Exactech) was implanted. Twenty-six patients were treated without patellar resurfacing and 21 with patellar resurfacing. Clinical evaluations were performed using the International Knee Society and the Hospital for Special Surgery scores. Ten patients with patellar resurfacing and 10 patients without patellar resurfacing were also studied with motion analysis during stair climbing; 10 healthy subjects were studied for statistical comparison. FINDINGS: Clinical passive knee flexion, International Knee Society Function and Hospital for Special Surgery scores were significantly higher in the patellar resurfacing group. During stair climbing, active knee joint range of motion during the stance phase was greater in patients with patellar resurfacing. The maximum adduction moment was significantly higher in the group without patellar resurfacing. INTERPRETATION: Patients with patellar resurfacing demonstrated better clinical scores, and kinematic and kinetic data while ascending stairs.     

Interface pressure in transtibial socket during ascent and descent on stairs and its effect on patient satisfaction

BackgroundTranstibial amputees encounter stairs and steps during their daily activities. The excessive pressure between residual limb/socket may reduce the walking capability of transtibial prosthetic users during ascent and descent on stairs. The purposes of the research were to evaluate the interface pressure between Dermo (shuttle lock) and Seal-In X5 (prosthetic valve) interface systems during stair ascent and descent, and to determine their satisfaction effects on users.MethodsTen amputees with unilateral transtibial amputation participated in the study. Interface pressure was recorded with F-socket transducer (9811E) during stair ascent and descent at self-selected speed. Each participant filled in a questionnaire about satisfaction and problems encountered with the use of the two interface systems.FindingsThe resultant mean peak pressure (kPa) was significantly lower for the Dermo interface system compared to that of the Seal-In X5 interface system at the anterior, posterior and medial regions during stair ascent (63.14 vs. 80.14, 63.14 vs. 90.44, 49.21 vs. 66.04, respectively) and descent (67.11 vs. 80.41, 64.12 vs. 88.24, 47.33 vs. 65.11, respectively). Significant statistical difference existed between the two interface systems in terms of satisfaction and problems encountered (P < 0.05).InterpretationThe Dermo interface system caused less pressure within the prosthetic socket compared to the Seal-In X5 interface system during stair negotiation. The qualitative survey also showed that the prosthesis users experienced fewer problems and increased satisfaction with the Dermo interface system.     

Are there different gait profiles in patients with advanced knee osteoarthritis? A machine learning approach

BackgroundDetermine whether knee kinematics features analyzed using machine-learning algorithms can identify different gait profiles in knee OA patients.Methods3D gait kinematic data were recorded from 42 patients (Kellgren-Lawrence stages III and IV) walking barefoot at individual maximal gait speed (0.98 ± 0.34 m/s). Principal component analysis, self-organizing maps, and k-means were applied to the data to identify the most relevant and discriminative knee kinematic features and to identify gait profiles.FindingsFour different gait profiles were identified and clinically characterized as type 1: gait with the knee in excessive varus and flexion (n = 6, 14%, increased knee adduction and increased maximum and minimum knee flexion, p < 0.01); type 2: gait with knee external rotation, either in varus or valgus (n = 11, 26%, excessive maximum and minimum external rotation, p < 0.001); type 3: gait with a stiff knee (n = 17, 40%, decreased knee flexion range of motion, p < 0.001); and type 4: gait with knee varus ‘thrust’ and decreased rotation (n = 8, 19%, increased and reduced range of motion in the coronal and transverse plane, respectively, p < 0.05).InterpretationIn a group of patients with homogeneous Kellgren-Lawrence classification of knee OA, gait kinematics data permitted to identify four different gait profiles. These gait profiles can be a valuable tool for helping surgical decisions and treatment. To allow generalization, further studies should be carried with a larger and heterogeneous population.