Can parents prevent heavy episodic drinking by allowing teens to drink at home?

The current study examined whether permitting young women to drink alcohol at home during senior year of high school reduces the risk of heavy drinking in college. Participants were 449 college-bound female high school seniors, recruited at the end of their senior year. Participants were classified into one of three permissibility categories according to their baseline reports of whether their parents allowed them to drink at home: (a) not permitted to drink at all; (b) allowed to drink with family meals; (c) allowed to drink at home with friends. Repeated measures analysis of variance was used to compare the drinking behaviors of the three groups at the time of high school graduation and again after the first semester of college. Students who were allowed to drink at home during high school whether at meals or with friends, reported more frequent heavy episodic drinking (HED) in the first semester of college than those who reported not being allowed to drink at all. Those who were permitted to drink at home with friends reported the heaviest drinking at both time points. Path analysis revealed that the relationship between alcohol permissiveness and college HED was mediated via perceptions of parental alcohol approval.     

Experimental manipulation of attentional biases in heavy drinkers: do the effects generalise?

Rationale In heavy drinkers, training attention towards alcohol cues increases alcohol craving, but it is not clear if effects of ‘attentional training’ generalise to novel stimuli and measurement procedures. Objectives We investigated possible generalisation of attentional training to novel alcohol cues and other methods of measuring cognitive bias. Materials and methods A modified visual probe task was used to train participants to direct their attention either towards (‘attend alcohol’ group) or away from (‘avoid alcohol’ group) alcohol cues; attentional bias was not manipulated in a control group (total N = 60). After attentional training, we measured cognitive bias (using visual probe, modified Stroop, flicker-induced change blindness and stimulus–response compatibility tasks), alcohol craving and alcohol consumption. Results Attentional bias for alcohol cues increased in the ‘attend alcohol’ group, and this effect generalised to novel stimuli, but not to other cognitive bias tasks. In the ‘avoid alcohol’ group, attentional bias was reduced for the stimuli that were used during attentional training, but these effects did not generalise to different stimuli or cognitive bias tasks. Alcohol craving increased among participants in the ‘attend alcohol’ group, but only among participants who were aware of the experimental contingencies during attentional training. There were no group differences in alcohol consumption. Conclusions The effects of attentional training show limited generalisation to different alcohol cues and methods of measuring cognitive bias. Experimentally increased attentional bias seems to increase subjective craving, but only among participants who are aware of the experimental contingencies that were in place during attentional training.     

Negative alcohol consumption outcome associations in young and mature adult social drinkers: a route to drinking restraint?

Alcohol 'cognitions' were explored using an implicit methodology [Stacy, Leigh and Weingardt, 1994]. In Study 1, an Associations Questionnaire was developed with young adult undergraduates (median=20 years) comprising culturally available (i.e., high-frequency occurrence) and idiosyncratic (i.e., low-frequency occurrence) positive and negative alcohol consumption outcomes and positive and negative outcomes of behaviors-other-than-alcohol consumption. In Study 2, the relationship was explored between the alcohol consumption of young adult undergraduates (median age = 19 years) and implicit alcohol-related associations made through the Associations Questionnaire. A significant positive relationship was found between consumption and positive and negative culturally available (experimental) outcomes but not for the other two types of (control) outcome. In Study 3, the relationship between alcohol consumption and alcohol-related associations was explored in mature adults (median = 45 years) with many more years' drinking experience. The results of Study 1 were replicated except that a significant positive relationship between consumption and some control outcomes was now found--e.g., negative outcomes of what where hitherto behaviors-other-than-alcohol consumption. In Study 4, however, using the same techniques that were used to develop the Associations Questionnaire in Study 1, an extended set of negative alcohol consumption outcomes was found in mature adults (median = 44 years) that included a proportion of the negative outcomes of behaviors-other-than-alcohol consumption that had served as controls in Studies 2 and 3. A reanalysis of the data from Study 3, with such items removed from the controls and designated 'new' negative alcohol consumption outcomes, showed a positive relationship between consumption and implicit alcohol-related associations made through these 'new' items of the Associations Questionnaire. The changing profile of associations with negative outcomes of consumption is discussed and related to negative expectancy research and drinking restraint.     

What is a drinking episode?

OBJECTIVE: The phrase "drinking episode" is used informally in many ways. However, a scientific understanding of the factors affecting the length of drinking episodes and the way treatment components affect these episodes requires rigorous operational definitions, supported by evidence for the appropriateness of these definitions. METHOD: Daily drinking data from two studies (Project MATCH and BETA) involving a total of 1,955 subjects are examined by survival analysis methods to determine the prognostic significance of different durations of postdrinking abstinence. The dependent measures are "time to next drink" and "time to heavy drinking." RESULTS: Curves relating postdrinking abstinence to subsequent drinking indicate that 1 day of abstinence has little prognostic significance. As the duration of abstinence increases from 1 up to 60 days, longer abstinence has a decelerating but still positive association with time to subsequent drinking/heavy drinking. There is no apparent threshold point beyond which further abstinence has no further effect. Inflections in the curves suggest, however, that intervals of 1, 2 or 4 weeks of continuous abstinence may be important milestones. These general patterns seem to hold up across samples despite significant quantitative differences across studies. CONCLUSIONS: These results suggest that two different definitions of "drinking episode" may be useful in examining treatment effects on drinking behavior. These analyses help to provide a foundation for further quantitative research on treatment effects on addictive behaviors over time.     

Does marital status predict long-term drinking? Five-year observations of dependent and problem drinkers

OBJECTIVE: Married individuals have lower rates of problem drinking, but little is known about this relationship in the context of other factors. This longitudinal analysis examines marital status with other individual predisposing, problem severity and social predisposing characteristics to understand its strength in predicting alcohol consumption over 5 years. METHOD: A probability sample of dependent (n = 600) and problem (n = 992) drinkers was recruited through consecutive adult intakes from a Northern California county's alcohol and drug treatment programs and through a general population survey. Annual volume of drinks consumed over a 5-year period-measured at baseline, and at 1, 3 and 5 years later-was estimated in four nested models using maximum likelihood estimation via PROC MIXED. RESULTS: In simpler models that examined only marital status, married individuals drank significantly less than those never married (p < .01 for problem drinkers and p < .05 for dependent drinkers); however, when our models added individual predisposing, problem severity and social predisposing characteristics, marital status was no longer significant in predicting a trajectory of decreased drinking. For problem drinkers, the following characteristics were more important than marital status in predicting alcohol consumption over the 5 years: individual predisposing characteristics (age, p < .001; income, p < .001; education, p < .001; and age of initiation of regular alcohol use, p < .001), problem severity (number of alcohol dependence symptoms, p < .001; number of alcohol-related social consequences, p < .001; and higher drug severity, p < .05) and social predisposing characteristics (family member with an alcohol problem, p < .05; the size of heavy alcohol- and drug-using social network, p < .05; and chemical dependency treatment in the prior year, p < .001). For those who were alcohol dependent, income (p < .05), number of alcohol dependence symptoms (p < .001), higher drug severity (p < .05) and a heavy alcohol- and drug-using social network (p < .05 ) were more important than marital status in predicting consumption. CONCLUSIONS: In longitudinal models, individual predisposing, problem severity and social predisposing characteristics are more important than marital status in predicting alcohol consumption.     

Does heavy drinking affect academic performance in college? Findings from a prospective study of high achievers

OBJECTIVE: This study examined the effects of heavy drinking, alcohol-related problems and drinking opportunities on academic performance (grade point average [GPA]) in a prospective cohort of college students attending the University of California at Berkeley. METHOD: Several waves of survey data were collected from 465 students beginning in the summer prior to their freshman year. Cross-sectional and regression analyses were conducted to determine whether heavy alcohol use, alcohol-related problems and drinking opportunities were associated with college GPA before and after controlling for demographics and high school GPA. RESULTS: Cross-sectional analyses generally revealed modest and nonsignificant associations between college GPA and measures of heavy alcohol use, alcohol-related problems and drinking opportunities in the first year of college. High school GPA was modestly associated with both heavy alcohol use and college GPA. Only a summative measure of alcohol-related academic problems was significantly associated with college GPA, but this relationship did not persist in a regression model that included high school GPA and student demographic characteristics as control variables. CONCLUSIONS: Heavy alcohol use, alcohol-related problems and drinking opportunities do not appear to have an important effect on students' academic performance, but additional research with longitudinal data from representative student samples is needed to confirm these findings.     

Exploring psychological benefits associated with moderate alcohol use: a necessary corrective to assessments of drinking outcomes?

The aim of this paper is to identify positive psychological concomitants of moderate alcohol consumption. Current research and public-health perspectives on alcohol emphasize harms disproportionately relative to benefits. The major exception is research establishing beneficial effects of moderate drinking on cardiovascular health and overall mortality. In addition, much observational and experiential data suggest the widespread prevalence of positive drinking experiences. This paper is one of the first attempts since 1985 to codify such benefits in epidemiological terms. Methodological difficulties in accomplishing this include defining moderate drinking, controlling for confounding variables, and establishing causality. Nonetheless, evidence of psychological benefits has been found in experimental, observational, interview, self-report, correlational, and some prospective research. These positive findings are in the areas of subjective health, mood enhancement, stress reduction, sociability, social integration, mental health, long-term cognitive functioning, and work income/disability. Problem drinkers and alcoholics also seek mood and other benefits from alcohol, but are more likely to drink to counteract negative feelings and to support their egos than are social drinkers. It is as yet impossible to determine to what extent moderate alcohol consumption causes positive psychological outcomes and to what extent it is part of a complex pattern of mutually reinforcing variables.     

Using collaterals to validate self-reports of problem drinkers: any impact on client attrition and quantity of drinking reported?

OBJECTIVE: To explore the impact of asking for a collateral on respondent attrition and the impact of providing versus not providing a collateral on self-reported drinking. METHOD: As part of a larger trial assessing the efficacy of self-help materials for problem drinkers, respondents were randomly assigned to be asked or not asked to provide a collateral at the time of their 6-month follow-up. RESULTS: While there was no significant impact of client attrition, respondents who were asked for a collateral and provided one reported higher levels of alcohol consumption at the 6-month follow-up as compared to those who were asked for a collateral but did not provide one. CONCLUSIONS: Providing a collateral may have an impact on respondent's self-reported drinking. Alternate explanations for this finding are discussed.     

Brief alcohol intervention for college drinkers: How brief is?

Objective

Brief interventions for college student drinkers have been shown to be effective in reducing the amount of alcohol consumed as well as the number of alcohol-related problems. However, the duration of brief interventions varies substantially across studies.

Method

In the present study 114 undergraduate students who drank alcohol heavily were randomly assigned to a 10-minute brief intervention, a 50-minute brief intervention, or assessment-only control. The content of the active interventions was based on the same concept, and both interventions incorporated motivational interviewing components. Participants were assessed at baseline and 4-week post intervention on quantity of alcohol use, alcohol-related problems, and protective behavioral strategies.

Results

As hypothesized, there was a significant difference between participants in the 10-minute intervention and control condition regarding their alcohol consumption at 4-week follow up. However, there was no significant difference between the 50-minute intervention and the control condition on alcohol consumption. There were also no significant differences between active intervention conditions, and neither intervention showed advantages for reducing problems or increasing protective behaviors relative to the control condition.

Conclusions

Results suggest a very brief intervention can impact short-term alcohol use outcomes, with potentially no advantage of longer interventions for this population.     

Respiratory tract infections: at-risk patients, who are they? Implications for their management with levofloxacin

Two of the most serious respiratory tract infections are community-acquired pneumonia (CAP) and acute exacerbations of chronic bronchitis (AECB). The most common pathogens found in patients with these infections are Haemophilus influenzae and Streptococcus pneumoniae. Pseudomonas aeruginosa is also relatively common, particularly in elderly patients with AECB. S. pneumoniae and P. aeruginosa are also of concern in relation to the development of resistance to antimicrobial drugs. The administration of antibiotics at doses that result in concentrations exceeding the mutant prevention concentration at the site of infection is one strategy to prevent the development of drug-resistant pathogens. AECB is associated with a high risk of in-hospital mortality, particularly in patients treated in the intensive care unit. CAP is also associated with significant risks and often requires treatment under hospital supervision. Several patient-related factors help identify those patients who are most at risk of mortality and morbidity. Treatment should be tailored towards the severity of the disease. The fluoroquinolones, such as levofloxacin, are an effective treatment option for AECB and CAP. Compared with many other antibiotics, resistance to levofloxacin remains low for most infecting pathogens. The oral bioavailability of levofloxacin is over 99%, enabling simple switching from intravenous to oral therapy during treatment. It is also preferentially distributed to compartments in the lung, thus achieving high concentrations at the site of respiratory tract infections. Combined with cover of the major infecting pathogens found in patients with AECB and CAP, and a cost-effective treatment compared with many alternative therapies, levofloxacin is an attractive option for the treatment of at-risk patients with these respiratory tract infections.     

Decreased drinking in adults with co-occurring cannabis and alcohol use disorders in a treatment trial for marijuana dependence: Evidence of a secondary benefit?

The purpose of the present study was to investigate whether cannabis dependent users who met criteria for a secondary diagnosis of alcohol use disorder (AUD) would increase their use of alcohol in response to decreasing their use of marijuana in a behavioral treatment trial for cannabis use disorder (CUD). This phenomenon is commonly known as “substance substitution.” Participants were randomly assigned to one of four 9-session treatment conditions with cannabis and alcohol use measured at baseline, posttreatment, and at 4 follow-ups through 14 months. Of those enrolled (n = 198), 27 (13.6%) also met criteria for AUD. Linear mixed models were used to analyze alcohol use over time with cannabis use and time as predictors. Findings demonstrated that there were no associations between declines in cannabis use and changes in alcohol consumption in the full sample. However, among those with CUD who also had AUD, declines in cannabis use significantly predicted concurrent declines in alcohol use (p < .05). This study did not find evidence of substance substitution among individuals receiving treatment for CUD. Contrary to expectations, the results indicated that individuals with AUD were more likely to decrease, rather than increase, their alcohol use when they reduced their marijuana use. Treatment for CUD in this study appeared to result in improvements in substance use generally, at least for those with comorbid AUD.