血管内栓塞治疗颅内动脉瘤时间窗的临床评价

Objective To evaluate the effects of endovascular embolization treatment for intracranial aneurysms in different time. Methods To respectively analyse the clinical data of 165 cases of ruptured intracranial aneurysm treated by endovascular treatment. The patients were divided into 3 groups accrodding to the time of treatment, endovascular reatments were stated within 24 h in group A, 3 d in group B and after 3 d in group C. The outcomes and complications including rebleeding, vasospasm and hydrocephala of 3 groups were compared. Results The incidence of rebleeding, vasospasm and hydrocephala in group A and B were lower than that in group C ( P ＜ 0. 01 ). Vasospasm in group C was most severe. The GOS score was highest in group A and lowest in group C. Conclusion Endovascular embolization treatment is a safe and effective method for treatment of intracranial aneurysm. The timing of treatment is a major factor for technical success.     

血管内栓塞治疗颅内动脉瘤时间窗的临床评价

Objective To evaluate the effects of endovascular embolization treatment for intracranial aneurysms in different time. Methods To respectively analyse the clinical data of 165 cases of ruptured intracranial aneurysm treated by endovascular treatment. The patients were divided into 3 groups accrodding to the time of treatment, endovascular reatments were stated within 24 h in group A, 3 d in group B and after 3 d in group C. The outcomes and complications including rebleeding, vasospasm and hydrocephala of 3 groups were compared. Results The incidence of rebleeding, vasospasm and hydrocephala in group A and B were lower than that in group C ( P ＜ 0. 01 ). Vasospasm in group C was most severe. The GOS score was highest in group A and lowest in group C. Conclusion Endovascular embolization treatment is a safe and effective method for treatment of intracranial aneurysm. The timing of treatment is a major factor for technical success.     

夹闭术与血管内治疗破裂性宽颈动脉瘤的比较

目的 回顾性分析破裂性宽颈动脉瘤夹闭术及血管内治疗的疗效.方法 确诊的143例破裂性宽颈动脉瘤患者分别采用夹闭术(83例)和血管内治疗(60例),对两组患者并发症发生率、复发率及出院后6个月改良Rankin评分进行比较.结果 两组的并发症发生率、复发率及改良Rankin评分差异有统计学意义(P＜0.05),血管内治疗组较夹闭术组复发率高,但并发症少,患者预后好.结论 血管内治疗破裂性宽颈动脉瘤安全、有效,患者有着更好的生存质量.

Abstract：

Objective To analyze the clinical efficacy of clipping and endovascular treatment for ruptured wide-necked aneurysm Methods 143 patients with ruptured wide- necked aneurysm were treated by clipping ( n =83) or endovascular treatment ( n =60). Their complication rates、recurrence rates and modified Rankin scale scores at six months after leaving hospital were evaluated. Results The complication rate in endovasular treatment group was less than that in clipping group( P ＜ 0.05) significantly. The recurrence rate in clipping group was less than that in endovasular treatment group( P ＜ 0. 05) significantly. The modified Rankin scale in endovasular embolization group was less than that in clipping group( P ＜ 0. 05) significantly. Higher recurrence rate and lower complication rate were observed in endovasular treatment group. Patients with endovascular treatment had better prognosis. Conclusion Endovascular treatment for ruptured wide - necked aneurysm is efficient and safe. Better quality of life could be achieved.     

夹闭术与血管内治疗破裂性宽颈动脉瘤的比较

Objective To analyze the clinical efficacy of clipping and endovascular treatment for ruptured wide-necked aneurysm Methods 143 patients with ruptured wide- necked aneurysm were treated by clipping ( n =83) or endovascular treatment ( n =60). Their complication rates、recurrence rates and modified Rankin scale scores at six months after leaving hospital were evaluated. Results The complication rate in endovasular treatment group was less than that in clipping group( P ＜ 0.05) significantly. The recurrence rate in clipping group was less than that in endovasular treatment group( P ＜ 0. 05) significantly. The modified Rankin scale in endovasular embolization group was less than that in clipping group( P ＜ 0. 05) significantly. Higher recurrence rate and lower complication rate were observed in endovasular treatment group. Patients with endovascular treatment had better prognosis. Conclusion Endovascular treatment for ruptured wide - necked aneurysm is efficient and safe. Better quality of life could be achieved.     

夹闭术与血管内治疗破裂性宽颈动脉瘤的比较

Objective To analyze the clinical efficacy of clipping and endovascular treatment for ruptured wide-necked aneurysm Methods 143 patients with ruptured wide- necked aneurysm were treated by clipping ( n =83) or endovascular treatment ( n =60). Their complication rates、recurrence rates and modified Rankin scale scores at six months after leaving hospital were evaluated. Results The complication rate in endovasular treatment group was less than that in clipping group( P ＜ 0.05) significantly. The recurrence rate in clipping group was less than that in endovasular treatment group( P ＜ 0. 05) significantly. The modified Rankin scale in endovasular embolization group was less than that in clipping group( P ＜ 0. 05) significantly. Higher recurrence rate and lower complication rate were observed in endovasular treatment group. Patients with endovascular treatment had better prognosis. Conclusion Endovascular treatment for ruptured wide - necked aneurysm is efficient and safe. Better quality of life could be achieved.     

Hunt-Hess Ⅰ～Ⅲ级动脉瘤性蛛网膜下腔出血早期手术术前腰大池外引流的临床观察

目的 探讨Hunt-Hess Ⅰ～Ⅲ级动脉瘤性蛛网膜下腔出血(SAH)早期手术术前腰大池外引流的临床疗效.方法 将早期手术的Hunt-Hess Ⅰ～Ⅲ级动脉瘤性SAH患者分为术前腰大池外引流组(47例)和术后腰大池外引流组(54例),分析两组病例的疗效差异.结果 术前腰大池外引流组无置管导致的动脉瘤再破裂出血病例,其术中动脉瘤破裂、症状性脑血管痉挛、慢性脑积水的发生率分别为8.5%、12.8%、12.8%,均低于术后腰大池外引流组的11.1%、20.4%、14.8%.结论 术前行腰大池外引流无增加Hunt-Hess Ⅰ～Ⅲ级动脉瘤性SAH早期手术患者动脉瘤再破裂出血的风险,并且可降低症状性脑血管痉挛和慢性脑积水的发生率.

Abstract：

Objective To explore the therapeutic effect of preoperative external hunbar drainage in Hunt and Hess grade Ⅰ～Ⅲ patients with subarachnoid hemorrhage ( SAH ) undergoing early surgery for intracranial aneurysms. Method The 101 cases of grade Ⅰ～Ⅲ patients according to the classification of Hunt and Hess with early surgical treatment were devided into preoperative external lumbar drainage group(47 cases) and postoperative external lumbar drainage group(54 cases).Outcome of patients with different external drainage of cerebrospinal fluid was analyzed. Results There was no case of aneurysm rebleeding could be associated with preoperative spinal drain placement. Tne incidences of intraoperative aneurysm rapture in preoperative external lumbar drainage group was 8. 5%,which was lower than 11. 1% in postoperative external lumbar drainage group. The incidences of symptomatic cerebral vasospasm and chronic hydrocephalus in preoperative external lumbar drainage group were 12. 8% and 12.8% ,which were lower than 20. 4% and 14. 8% in postoperative external lumbar drainage group. There all were not significant differences between the two groups. Conclusions Preoperative external lumbar drainage wont increase a risk of rebleeding for grade Ⅰ～Ⅲ patients with aneurysmal SAH undergoing early surg ery. Furthermore, it can decrease the incidences of symptomatic cerebral vasospasm and chronic hydrocephalus,which is a safe and useful method of removing bloody cerebrospinal fluid.     

颅内夹层动脉瘤血管内栓塞治疗

Objective To analyze the clinical features of intracranial dissecting aneurysm and summarize the experience of its endovascular embolization. Methods 16 cases of intracranial dissecting aneurysm were treated by endovascular embolization. Among these 16 patients, 3 patients were treated with single stent or double stent placement technique, 9 patients were treated with stent- assisted coil embolization technique, 3 patients were ball artery occluded using the balloon - assisted or coil - assisted technique, and 1 patient was treated by simple coil embolization. Results Out of the 16 patients, 9 cases were completely occluded ( including parent artery occlusion cases ), 3 cases were subtotally occluded, 4 cases were incompletely occluded ( including cases of stent implantation ). Followed up for 6 months to 3 years, in addition to 1 case of early death, GOS evaluation results were respectively: grade Ⅰ 8 cases, grade Ⅱ 4 cases, grade Ⅲ 2 cases, grade Ⅳ 1 case. Cerebral angiography was carried out in 8 follow - up patients. No recurrence was watched in 7 cases, aneurysm neck recanalization was watched in 1 case, follow up was continued. Conclusion According to different localization of intracranial aneurysm and different pathological features, different methods of endovascular embolization are selected. It is the safe and effective treatment of dissecting aneurysm.     

颅内夹层动脉瘤血管内栓塞治疗

Objective To analyze the clinical features of intracranial dissecting aneurysm and summarize the experience of its endovascular embolization. Methods 16 cases of intracranial dissecting aneurysm were treated by endovascular embolization. Among these 16 patients, 3 patients were treated with single stent or double stent placement technique, 9 patients were treated with stent- assisted coil embolization technique, 3 patients were ball artery occluded using the balloon - assisted or coil - assisted technique, and 1 patient was treated by simple coil embolization. Results Out of the 16 patients, 9 cases were completely occluded ( including parent artery occlusion cases ), 3 cases were subtotally occluded, 4 cases were incompletely occluded ( including cases of stent implantation ). Followed up for 6 months to 3 years, in addition to 1 case of early death, GOS evaluation results were respectively: grade Ⅰ 8 cases, grade Ⅱ 4 cases, grade Ⅲ 2 cases, grade Ⅳ 1 case. Cerebral angiography was carried out in 8 follow - up patients. No recurrence was watched in 7 cases, aneurysm neck recanalization was watched in 1 case, follow up was continued. Conclusion According to different localization of intracranial aneurysm and different pathological features, different methods of endovascular embolization are selected. It is the safe and effective treatment of dissecting aneurysm.     

西藏高原地区血管内介入治疗破裂颅内动脉瘤

目的 探讨西藏高原地区经血管内介入治疗破裂出血的颅内动脉瘤的安全性、有效性及可行性.方法 回顾性分析2010年1月至2010年11月我院经血管内介入治疗的8例破裂出血的颅内动脉瘤.8例患者均行DSA检查确诊,并根据动脉瘤的特点实施个性化血管内介入治疗:5例行弹簧圈栓塞术,2例行支架辅助弹簧圈栓塞术,1例行单纯支架贴敷术.结果 8例中完全栓塞6例,次全栓塞1例,单纯支架贴敷1例.术中复查DSA显示:动脉瘤显影消失7例,单纯支架置入后瘤腔内对比剂滞留1例.1例宽颈动脉瘤行支架辅助弹簧圈栓塞术后出现对侧肢体偏瘫(肌力0级),经给予加强抗凝、抗血小板聚集、改善微循环等治疗后,下肢肌力恢复至Ⅴ级,上至肌力恢复至接近Ⅴ级.除术前Hunt-Hess分级Ⅳ级、GCS评分4分的1例因继发严重脑积水恢复至Hunt-Hess分级Ⅲ级、GCS评分7分外,其余7例均恢复正常.门诊随访1-5个月,无再出血或缺血事件发生.结论 高原地区经血管内介入治疗破裂出血的颅内动脉瘤是安全、有效的,但围手术期的处理具有高原特色.

Abstract：

Objective To evaluate the safety, efficacy and feasibility of endovascular interventional therapeutic techniques for ruptured hemorrhagic intracranial aneurysms in highland in Tibet. Methods Retrospectively analyzed the therapeutic effects of endovascular interventional treatment for ruptured hemorrhagic intracranial aneurysms in 8 cases in highland in Tibet 8 cases were performed DSA for accurate diagnosis and individualized endovascular interventional treatment were undergone according to the feature of the aneurysms; coiling in 5 cases, coiling with assistance of stent in 2 and pure stenting in 1. Results Among the 8 cases complete embolization was gained in 6 and hypo - complete embolization in 1. DSA review during procedure showed the image of aneurysm disappeared in 7 cases and retention of contrast agent inside the aneurysm in the case which was purely stented. Contralateral hemiplegia of limbs which muscle strength was 0 grade occurred in 1 case with wide - necked aneurysm treated by coiling with stent assistance after procedure. After the intensive treatment of antiplatelet, anticoagulation and to improve microcirculation, the muscle strength recovered to Ⅴ grade in the lower limb and near Ⅴ grade in the upper limb. After procedure except 1 case whose Hunt & Hess grade was in Ⅵ and GCS was 4 improved Hunt & Hess grade to Ⅲ and GCS to 4 because of secondary severe hydrocephalus, the other cases were all well recovered. During 1 to 5 months following - up of outpatient no re - hemorrhagic or ischemic event occurred. Conclusions Endovascular interventional treatment is safe, mini- invasive, effective and feasible for ruptured hemorrhagic intracranial aneurysms in highland in Tibet, but the peri - operative management was highland characteristic.     

颅内夹层动脉瘤血管内栓塞治疗

目的 分析颅内夹层动脉瘤的临床特点,总结血管内栓塞治疗的经验.方法 对16例颅内夹层动脉瘤患者采用血管内栓塞治疗,其中3例采用单支架或双支架置入术,9例应用支架辅助下弹簧圈栓塞技术,3例使用球囊或弹簧圈辅助下球囊载瘤动脉闭塞术,1例使用单纯弹簧圈动脉瘤栓塞术.结果 16例中,动脉瘤完全闭塞9例(包括载瘤动脉闭塞病例),次全闭塞3例,不全闭塞4例(包括支架植入病例).随访6个月-3年,除早期1例死亡外,GOS结果评定:Ⅰ级8例,Ⅱ级4例,Ⅲ级2例,Ⅳ级1例.8例随访时脑血管造影,7例未见复发,1例瘤颈再通,正在随访.结论 根据颅内夹层动脉瘤的不同部位、不同病理特点,选择不同的血管内栓塞治疗方法,是治疗夹层动脉瘤安全、有效的方法之一.

Abstract：

Objective To analyze the clinical features of intracranial dissecting aneurysm and summarize the experience of its endovascular embolization. Methods 16 cases of intracranial dissecting aneurysm were treated by endovascular embolization. Among these 16 patients, 3 patients were treated with single stent or double stent placement technique, 9 patients were treated with stent- assisted coil embolization technique, 3 patients were ball artery occluded using the balloon - assisted or coil - assisted technique, and 1 patient was treated by simple coil embolization. Results Out of the 16 patients, 9 cases were completely occluded ( including parent artery occlusion cases ), 3 cases were subtotally occluded, 4 cases were incompletely occluded ( including cases of stent implantation ). Followed up for 6 months to 3 years, in addition to 1 case of early death, GOS evaluation results were respectively: grade Ⅰ 8 cases, grade Ⅱ 4 cases, grade Ⅲ 2 cases, grade Ⅳ 1 case. Cerebral angiography was carried out in 8 follow - up patients. No recurrence was watched in 7 cases, aneurysm neck recanalization was watched in 1 case, follow up was continued. Conclusion According to different localization of intracranial aneurysm and different pathological features, different methods of endovascular embolization are selected. It is the safe and effective treatment of dissecting aneurysm.     

动脉硬化型颅内动脉瘤的综合治疗

目的 总结和探讨动脉硬化性动脉瘤的综合治疗方法。方法 对16例动脉硬化型动脉瘤病人进行了综合治疗，用GDC进行血管内动脉瘤栓塞治疗其病因；腰穿置管稳压引流缓解症状，防止出现急性脑积水：通窍活血汤防止迟发性缺血性脑损害。结果 在保持载瘤动脉通畅的情况下，15例动脉瘤完全栓塞，1例98％栓塞，病人头痛时间明显缩短，所有患者无再出血、脑血管痉挛或迟发性缺血性脑损害等并发症发生。结论 对硬化型动脉瘤应采取综合性治疗能明显提高疗效、缩短病程、降低致残率。     

超早期行血管内栓塞术联合持续性腰大池引流术治疗高级别动脉瘤性蛛网膜下腔出血的预后分析

目的分析颅内囊状动脉瘤Hunt-Hess Ⅳ~Ⅴ分级患者超早期行血管内栓塞术联合持续性腰大池引流术的预后。 方法回顾性分析大连大学附属中山医院神经外一科自2014年1月至2017年12月收治的颅内囊状动脉瘤Hunt-Hess Ⅳ~Ⅴ分级患者32例（Ⅳ级24例,Ⅴ级8例）的临床资料,其中16例超早期行血管内栓塞术联合持续性腰大池引流术（A组）,另外16例患者入院超早期行血管内栓塞术（B组）;根据术后CT、TCD及临床症状,判断是否发生脑血管痉挛、脑积水及脑梗死,记录2组患者住院时间,对2组患者治疗后第1、3、6月的预后进行评价。 结果A组发生脑血管痉挛5例、脑积水9例、脑梗死6例,住院时间（25±8）d;B组发生脑血管痉挛8例、脑积水11例、脑梗死9例,住院时间（28±9）d;2组比较差异有统计学意义（P<0.05）。2组治疗后1个月GCS评分比较,差异无统计学意义（P>0.05）;治疗后3、6个月改良Rankin量表评分比较,差异均有统计学意义（P<0.05）。 结论颅内囊状动脉瘤Hunt-Hess Ⅳ~Ⅴ分级患者术后持续腰大池引流可减少脑血管痉挛、脑积水及脑梗死等并发症的发生,减少住院时间,提高患者术后3个月及半年恢复水平。     

前交通动脉瘤形态学特点与栓塞可行性关系

目的总结栓塞治疗前交通动脉瘤的经验体会,探讨其适应证、技术要点、形态学特点与栓塞可行性的关系及并发症的防治。方法回顾性分析栓塞治疗36例破裂前交通动脉瘤患者的临床资料、栓塞过程以及疗效。结果36例中成功栓塞34例,其中22例100％栓塞,5例95％栓塞,7例90％栓塞。术中动脉瘤破裂2例,1例死亡。5例出现严重血管痉挛。1例死于术后并发症。随访6～58个月,无术后再出血病例,3例复发。结论栓塞是治疗前交通动脉瘤的一种微创、相对安全有效的治疗方法。前交通动脉瘤形态学特点是治疗前评估血管内栓塞是否成功的重要依据。     

颅内动脉瘤的个体化血管内介入治疗

目的探讨个体化血管内介入治疗颅内动脉瘤的经验。方法回顾性分析30例颅内动脉瘤病人(32个动脉瘤)的临床资料,均采用血管内介入治疗。其中行单纯弹簧圈栓塞治疗动脉瘤15个,支架辅助弹簧圈栓塞治疗12个,球囊辅助弹簧圈栓塞治疗2个,载瘤动脉闭塞治疗3个。结果动脉瘤致密栓塞22个,大部栓塞7个,载瘤动脉闭塞后不显影3个。术中动脉瘤破裂2例,严重血管痉挛1例。随访1～72个月,恢复良好25例,轻残1例,重残1例,死亡3例。结论个体化血管内介入治疗是处理颅内动脉瘤安全、有效的方法;合理选择介入技术及正确处理并发症是治疗成功的关键。     

颅内动脉瘤的血管内栓塞治疗

目的探讨血管内栓塞治疗颅内动脉瘤的疗效。方法回顾性分析了34例颅内动脉瘤的血管内栓塞治疗,其中3例行球囊瘤内栓塞治疗,5例行载瘤动脉球囊闭塞术,26例行GDC栓塞治疗。结果26例GDC栓塞患者中,100%栓塞16例,90~95%栓塞8例,不到90%栓塞2例;术中出现脑血管痉挛3例,脑血栓形成2例,未出现动脉瘤破裂;34例病人出院时按格拉斯哥预后评分(GOS)评价结果,良好26例,中残6例,重残2例,无植物生存及死亡病例;术后随访无再出血病例。结论由于血管内治疗技术和材料的不断进步,尤其是GDC的广泛应用,多数颅内动脉瘤可以进行有效的血管内栓塞治疗。     

前交通动脉瘤血管内栓塞治疗

目的总结以电解可脱性弹簧圈(GDC)血管内栓塞治疗前交通动脉瘤的技术要点、并发症及其防治经验,并评价其治疗效果.方法对46例前交通动脉瘤患者采用经皮股动脉穿刺行全脑选择性血管造影术,应用GDC进行动脉瘤囊内栓塞;术后早期处理出血并有效的对症治疗.结果成功栓塞46个动脉瘤,其中44例临床痊愈,2例死亡,死亡率4.3%.术中动脉瘤腔100%闭塞者41例,95%闭塞者3例,90%闭塞者2例.术中动脉瘤破裂1例,并发脑血栓1例,并发脑血管痉挛4例;术后无弹簧圈末端逸出,1例复发者经二次补充GDC栓塞而治愈.术后随访3～50个月均无再出血.结论对前交通动脉瘤采用GDC进行血管内囊内栓塞疗效可靠;早期诊断、早期治疗、正确处理术中并发症、提高栓塞技术及积极有效的术后处理是减少术后并发症、提高治愈率的重要方法.     

血管内栓塞治疗多发性颅内动脉瘤

目的评价血管内栓塞治疗多发性颅内动脉瘤的安全性与有效性。方法回顾性分析经血管内栓塞治疗16例多发性颅内动脉瘤（共38个动脉瘤）患者的临床资料。36个动脉瘤在前循环,2例病人分别有1个动脉瘤在后循环。根据Hunt—Hess评分,Ⅰ级5例,Ⅱ级6例,Ⅲ级3例,Ⅳ级2例。结果15例病人一次性将所有动脉瘤栓塞,1例仅栓塞责任动脉瘤,未能栓塞的动脉瘤二期手术夹闭。无死亡病例,临床随访6个月以上,所有病例无再出血;预后按GOS评分,良好11例,轻残3例,重残1例,植物生存1例。结论血管内栓塞治疗多发性颅内动脉瘤是安全有效的。诊断明确后应尽早治疗责任动脉瘤;然后再根据未破裂动脉瘤的处理原则,选择性栓塞其它未破裂动脉瘤。     

颅内动脉瘤破裂中期的血管内治疗

目的 探讨颅内动脉瘤破裂中期(4-10d)血管内栓塞治疗的安全性、技术要点及疗效.方法 根据在DSA影像上有无脑血管痉挛(CVS)将全组48例患者分为两组:A组26例为有CVS者,B组22例为无CVS者.全组均在蛛网膜下腔出血(SAH)后4-10d采用可脱性微弹簧圈对破裂性颅内动脉瘤行囊内栓塞.患者均在治疗后3个月时行Glasgow预后评分(COS),治疗结果经,检验.结果 全组动脉瘤腔100%闭塞42例,95%闭塞者4例,90%闭塞者2例;其中100%闭塞的患者中A组22例,B组20例,两组完全栓塞率比较差别无统计学意义(χ<'2>=0.43,P>0.05).术中出现与栓塞技术相关的并发症3例.A组GoS:ⅠI级10例,Ⅱ级5例,Ⅲ级7例,Ⅳ级1例,Ⅴ级3例;B组COS:Ⅰ级17例,Ⅱ级3例,Ⅲ级1例,Ⅳ级0例,Ⅴ级1例.全组死亡率8.3%.术后随访3-58个月均无再出血及动脉瘤复发.结论 动脉瘤破裂后在中期(4-10d)并不是都伴有CVS;在该期对破裂性颅内动脉瘤采用可脱性弹簧圈进行血管内囊内栓塞安全可行、疗效可靠.     

自发性蛛网膜下腔出血的病因诊断及介入治疗

目的通过数字减影脑血管造影（DSA）对自发性蛛网膜下腔出血（SAH）作病因诊断及颅内动脉瘤的介入治疗。方法对246例SAH患者行DSA检查以明确其出血原因。对138例确诊动脉瘤患者用GDC或EDC行血管内栓塞治疗。结果246例SAH患者DSA检查发现颅内动脉瘤155例（63．0％），其中动脉瘤合并脑动静脉畸形（AVM）3例，动脉瘤合并烟雾病1例，AVM 15例（6．1％），烟雾病10例（4.1％），高血压动脉硬化39例（15，9％），原因不明27例（11．0％）。138例颅内动脉瘤栓塞患者中1例术中出血死亡，1例术后1h再出血死亡；动脉瘤栓塞术后经DSA随访90例，随访时间为1个月至6．5年，发现13例再通（其中2例因再出血行DSA复查发现再通），再通率为14.4％，13例再通患者经再栓塞后未发生再出血。结论自发性SAH的主要原因是脑动脉瘤，DSA是明确SAH病因的可靠方法，GDC或EDC血管内栓塞治疗颅内动脉瘤安全有效，但有一定复发率，故应注意随访。     

血管内治疗颅内动脉瘤的临床分析

目的探讨血管内治疗颅内动脉瘤的临床效果。方法回顾性分析2011年1月至2014年6月血管内治疗的257例颅内动脉瘤患者的临床资料。结果 257例患者共261枚动脉瘤,其中259枚动脉瘤顺利栓塞,2枚动脉瘤未能栓塞。术后即刻造影显示：Raymond分级Ⅰ级栓塞211枚,Ⅱ级37枚,Ⅲ级11枚。术中出现脑血管痉挛13例、动脉瘤破裂再出血5例、支架内急性血栓形成3例、弹簧圈部分脱出至载瘤动脉2例。术前Hunt-Hess分级Ⅳ级患者3例和术中动脉瘤破裂再出血患者1例死亡。237例患者出院后随访3~42月,改良Rankin评分0~2分229例,3~5分8例;9例动脉瘤复发和2例动脉瘤破裂再出血均再次栓塞治疗,其余患者未发生动脉瘤复发和再出血,并且17枚Ⅱ级栓塞和5枚Ⅲ级栓塞的动脉瘤达到Ⅰ级栓塞。结论血管内治疗是一种有效、安全、微创的治疗颅内动脉瘤的方法。