卒中后睡眠障碍研究进展

卒中后睡眠障碍（post-stroke sleep disorders,PSSD）是一种常见但较少引起重视的卒中后并发症,其发生与疾病本身包括卒中部位、神经生物学及社会心理学因素相关。PSSD临床表现形式多样,需要结合相应的诊断标准及量表评估作出诊断,根据具体情况制订相应的治疗策略,在临床实践中多采用药物及非药物综合治疗的方法。本文就PSSD的临床表现、流行病学、相关危险因素、诊断及治疗做一综述,以期为PSSD的诊疗提供参考。     

卒中后睡眠障碍研究进展

睡眠障碍是卒中后严重且常见的并发症之一。具有发病率高、对卒中预后影响大的特点,不仅增加了患者的痛苦、影响了患者的康复,而且还会增加卒中复发的危险。因此卒中后睡眠障碍越来越受到神经科学界的重视。许多学者对卒中后出现睡眠障碍的患者进行了观察,并对卒中后睡眠障碍的机制进行了分析,本文对此进行综述。     

季节性情感障碍15例临床分析

季节性情感障碍１５例临床分析刘建勋临床发现不少双相情感障碍和复发性重性抑郁症患者其发病与季节有关。每年秋、冬季抑郁发作，春、夏季则出现躁狂。１９８４年Ｒｏｓｅｎｔｈａｌ将这种发病与季节有关的疾病命名为季节性情感障碍（ＳＡＤ）。迄今国内对ＳＡＤ的报道及...     

卒中后睡眠障碍

睡眠障碍是卒中后常见的并发症之一,会影响卒中患者的预后及生活质量。卒中后睡眠障碍的原因不完全清楚,主要与梗死部位、神经递质、社会心理因素等有关。它主要分为呼吸相关性睡眠障碍和非呼吸相关性睡眠障碍两类,其中呼吸相关性睡眠障碍是较常见的类型。在卒中后睡眠障碍的治疗方面,药物治疗和非药物治疗相辅相成。临床医师应增强意识,尽早识别卒中后睡眠障碍类型,予以干预,以期改善患者预后,提高患者生活质量。     

快速循环双相情感障碍研究进展

自DunnerDL.于1974年提出情感障碍中的快速循环(rapidcycling,RC)的诊断概念以来,至今已25年,人们对这一具有频繁循环发作及治疗困难的临床现象给予很大重视,进行多领域研究,对它的认识逐渐加深。现将90年代以来最新研究进展介绍如下。作者单位:518003　深圳市精神卫生研?..     

卒中相关睡眠障碍

<正>卒中相关睡眠障碍（stroke-related sleep disorders,SSD）是卒中后常见症状之一,SSD是指在卒中后首次出现或卒中前已有的睡眠障碍在卒中后持续存在或加重,并达到睡眠障碍诊断标准的一组临床综合征。SSD分为两种类型：卒中后睡眠障碍和卒中伴随睡眠障碍[1],主要包括失眠障碍、睡眠呼吸障碍（sleep disorderedbreathing,SDB）、昼夜节律相关睡眠-觉醒障碍（circadianrhythmsleepwakedisorders,CRSWDs）、中枢性过度睡眠、     

氟西汀胶囊与劳拉西泮片治疗卒中后情感障碍的效果分析

<正>脑卒中除带来持续性的躯体形式疼痛障碍外,还易伴明显的情感障碍,有报道脑卒中患者躯体部位疼痛加重或缓解,多与心理因素有关[1-2]。本次研究采用氟西汀胶囊与劳拉西泮片治疗脑卒中精神抑郁症,取得良好的效果,现报告如下。1资料与方法1.1一般资料选取2013-06—2014-06郑州人民医院收治的168例脑卒中后精神抑郁患者,男94例,女74例;年龄46     

重症情感障碍的遗传学研究

本文对重症情感障碍的流行病学、家系研究、病因学研究及诊断、治疗方面作一介绍.     

卒中后睡眠障碍的研究进展

随着对卒中研究的深入,逐渐发现睡眠障碍这一常见并发症与卒中的关系比预期的更加密切和复杂。例如,在卒中发作急性期,患者睡眠结构破坏,总睡眠时间缩短、睡眠效率降低、入睡潜伏期延长,而进入慢性期后随着受损脑组织结构和功能的恢复,患者的睡眠质量依然可以恢复到相对正常的状态。卒中病灶位于不同脑区可能出现不同形式的睡眠障碍,如睡眠呼吸暂停、日间过度嗜睡、发作性睡病、睡眠期运动异常和异态睡眠等。随着多导睡眠检测技术的广泛应用,临床医师与科研人员对卒中后睡眠障碍展开更多深入的研究。     

Mood and Cognitive Trajectories Over the First Year after Mild Ischemic Stroke

ObjectivesCognitive and mood dysfunction are major contributors to post-stroke disability. The longer-term trajectories of mood and cognition post-stroke remain unclear, as do which cognitive domains decline, improve, or remain stable after stroke, and in which patients. We aimed to characterize the cognitive trajectories of mild ischemic stroke survivors over one year compared to stroke-free controls, and to investigate whether symptoms of anxiety and depression were associated with cognitive function.Materials and methodsAll participants were tested with a neuropsychological test battery at 3-months and 12-months post-stroke, assessing attention/processing speed, memory, visuospatial function, executive function, and language. Anxiety and depression symptomatology were also assessed at both timepoints.ResultsStroke participants (N=126, mean age 68.44 years ±11.83, 87 males, median [Q1, Q3] admission NIHSS=2 [1, 4]) performed worse on cognitive tests and endorsed significantly higher depression and anxiety symptomatology than controls (N=40, mean age=68.82 years ±6.33, 25 males) at both timepoints. Mood scores were not correlated with cognitive performance. Stroke participants' scores trended higher across cognitive domains from 3- to 12-months but statistically significant improvement was only observed on executive function tasks.ConclusionStroke participants performed significantly worse than controls on all cognitive domains following mild ischemic stroke. Stroke participants only exhibited statistically significant improvement on executive function tasks between 3- and 12- months. Whilst anxiety and depression symptoms were higher in stroke participants, this was not correlated with cognitive performance. Further studies are needed to understand factors underlying cognitive recovery and decline after stroke.