耳石复位法治疗半规管良性阵发性位置性眩晕的临床研究

目的：评价耳石复位法治疗良性阵发性位置性眩晕（BPPV）疗效。方法：回顾分析2002年1月～2005年6月间治疗的230例BPPV患者的临床资料。根据半规管耳石假说,随机分成治疗组122例,对照组108例,分别接受耳石复位法和一般对症治疗。治疗结束后2周复查并评定疗效。结果：治疗组88例眩晕和眼震于治疗后立即或在2周内逐渐消失,18例改善,16例无效,治愈率72．1％,总有效率86．9％。对照组51例立即或在2周内逐渐消失,23例改善,34例无效,治愈率47．2％,总有效率68．5%。两组疗效相比差异有统计学意义。结论：鉴于耳石复位法治疗无明显禁忌证,方法简单,无痛苦和不良反应,一次性治疗疗效高,短期（1～3个月）随访无复发,因此认为该法可作为BPPV门诊治疗的首选方法。     

Model for demonstrating the canalith repositioning procedure

Benign positional vertigo is a common condition which may be easily treated with the canalith repositioning procedure. This procedure may be difficult for patients to understand and for medical staff to learn. This paper describes a model of the vestibular apparatus which may be used to demonstrate the procedure.     

颗粒复位法治疗后半规管良性阵发位置性眩晕

目的 评价颗粒复位法治疗良性阵发性位置性眩晕的效果。方法 对１９９６年７月－１９９８年６月间治疗的３１一半规管性良性性位置性眩晕患者进行回顾分析。地规管耳右症假说,患者接受１次颗粒复位法治疗。治疗结束２周后复查并评价疗效。结果 ２１例患者的眩晕和眼一立刻或在１－２周内逐渐消失。６例改善,４例无效。总有效率８７．１％。结论 颗粒复位法对大多数良性阵发性位置性眩晕患者有效,推荐作为治疗该的首选方法。     

外半规管良性阵发性位置性眩晕复位方法理论探讨

目的　基于标准空间半规管模型对外半规管良性阵法发性位置性眩晕复位方法进行理论探讨,分析各步骤的意义。方法　建立标准空间半规管模型并3D打印,通过对外半规管复位方法的模拟演示和观察,分析比较各种复位方法各步骤的意义和不足。结果　翻滚复位法自患侧卧位开始向健侧翻身,步骤包括仰卧位、健侧卧位和俯卧位再回到坐位是必要和足够的, Gufoni复位法实际上是翻滚复位法的简化,并无方法学上的优越性,而Appiani复位法仅对于壶腹嵴耳石脱落可能有作用。结论　基于标准空间半规管模型对复位方法进行模拟演示,分析各步骤是否合理,探讨对复位方法评估和改良是可行的。     

The Dix-Hallpike test and the canalith repositioning maneuver

The Dix-Hallpike test and the canalith repositioning maneuver (CRM) are used to diagnose and treat benign positional vertigo (BPV). Dix-Hallpike is the standard procedure for diagnosis of BPV, but if the horizontal canal is not tested for BPV and the Dix-Hallpike is only carried out once, the condition may not be diagnosed and appropriately treated. We describe our method of testing for BPV and treating it with CRM. The Dix-Hallpike test involves rapidly moving the patient from a sitting position to "head hanging," where the patient's head is at least 10 degrees below horizontal. This is performed initially for the posterior semicircular canals. If these movements fail to elicit vertigo and nystagmus, tests of the horizontal semicircular canals are performed by laying the patient on each side. Importantly, if there is no vertigo or nystagmus elicited by testing the horizontal semi-circular canals, the posterior semicircular canals are tested again. It appears that being held in the head hanging positions and then left and right lateral positions will often allow the canaliths to collect such that the Dix-Hallpike test will become positive. Failure to repeat the tests of the posterior semicircular canals may result in a falsely negative test. Testing the horizontal canals and repeating the Dix-Hallpike test will reduce the likelihood of patients undergoing extra testing or other consequences of misdiagnosis. If, during any of this testing, a movement elicits vertigo or nystagmus, the appropriate CRM is then carried out.     

The canalith repositioning procedure for benign positional vertigo: a meta-analysis

OBJECTIVE: To review the effectiveness of the canalith repositioning procedure (CRP) in the treatment of benign paroxysmal positional vertigo (BPPV) with a critical review of the literature and meta-analysis. STUDY DESIGN: Meta-analysis. METHODS: Studies eligible for inclusion were randomized, controlled trials of the CRP performed on clearly defined cases of BPPV. A total of nine studies meeting inclusion criteria were identified by two independent literature searches of Medline. Treatment and control groups were compared for symptom resolution and elimination of a positive Dix-Hallpike test. RESULTS: Patients treated with CRP were more likely to demonstrate symptom resolution (odds ratio [OR] 4.6; 95% confidence interval [CI] 2.8-7.6) and negative Dix-Hallpike (OR 5.2; 95% CI 3.0-8.8) at the time of first follow-up. The effect of CRP for symptom improvement was strongest within the first month after treatment (OR 4.1; 95% CI 3.1-5.2) with some decline thereafter (OR 2.8; 95% CI 1.7-3.9). Conversely, the ability of CRP to produce a negative Dix-Hallpike strengthened between the first month after treatment (OR 3.0; 95% CI 1.8-4.0) and later follow-up times (OR 5.0; 95% CI 3.9-6.1). CONCLUSIONS: The CRP is more effective than control in resolving vertigo and positive Dix-Hallpike associated with BPPV. This finding was consistent among a variety of studies using different study designs. Untreated patients may demonstrate symptom improvement with time; however, many will continue to have a positive Dix-Hallpike when examined. Resolution of vertigo in untreated patients is therefore most likely because of avoidance of provocative positions.     

不同方法治疗在良性阵发性眩晕的研究

目的探讨眩晕障碍量表(dizziness handicap inventory,DHI)对水平背地性眼震良性阵发性位置性眩晕(apo-geotropic nystagmus horizontal semicircular canal benign paroxysmal positional vertigo,apogeotropic HSC-BPPV)患者健康相关生活质量(quality of life,QOL)的评估意义。方法回顾性分析2014年3月至2015年5月期间确诊为apogeotropicHSC-BPPV的40例患者,采用汉化的英文版眩晕障碍量表,在治疗前和治疗后1个月进行QOL的调查和评估,比较采用不同耳石重置法的两组患者功能、情感、躯体三个方面的得分和总分。结果两组患者在治疗后的DHI各项分值和总分均明显低于治疗前,且差异有统计学意义(P<0.05);两组患者间比较,在治疗前和治疗后的DHI各项分值和总分均相当,差异无统计学意义(P>0.05);两组手法耳石复位全部成功。结论水平背地性眼震良性阵发性位置性眩晕患者,改良Nuti法和Gufoni法均能改善患者的QOL,汉化的英文版DHI在BPPV患者QOL评估中起着重要作用。     

The canalith repositioning maneuver in patients with benign positional vertigo

The canalith repositioning maneuver (CRM), as defined by Epley, can be an effective treatment for benign paroxysmal positional vertigo (BPPV). The staff at Başkent University’s Ear Nose and Throat Clinic performed CRM on 68 cases of canalithiasis in 64 BPPV patients from June 1996 to August 1997. Symptoms resolved after the first session in 49 patients (72%) and after the second session in 11 cases (16.2%). It was necessary to repeat the maneuver three times in two cases (2.9%) and four times in one patient (1.5%). Discounting three patients who were lost to follow-up, only two patients in our study did not respond to CRM treatment. There was no co-existing pathology found in all but two of the patients studied. Our experience indicates that unless there is no response to CRM or there is suspicion of an incorrect diagnosis, it is not necessary to perform diagnostic studies routinely for differentiating other neuro-otologic disorders prior to using CRM in BPPV patients diagnosed by the Dix-Hallpike test. Received: 10 November 1998 / Accepted: 4 March 1999     

上半规管良性阵发性位置性眩晕的临床分析

目的探讨上半规管良性阵发性位置性眩晕（anterior semicircular canal benign paroxysmal positional vertigo,AC-BPPV）的临床特点。方法回顾性分析16例AC-BPPV患者临床特点,并对耳石复位的疗效进行评估。结果①在Dix-Hallpike检查中,16例患者都诱发出垂直向下的眼震,其中11例双侧出现眼震,5例单侧出现眼震。②13例患者能明确受累侧别,其中5例为左侧AC受累,8例为右侧AC受累;3例受累侧别难以判断。③对13例受累侧别明确的患者采取反向颗粒复位手法治疗,5例痊愈,4例有效、4例无效;对4例无效患者再行Semont方法治疗,其中2例有效,2例仍无效。对3例受累侧别难以判断的患者采用Yacovino方法治疗后均痊愈。结论 AC-BPPV在临床中并不少见,耳石复位法疗效明确,可根据患者实际情况选择适当的复位方式。     

Therapeutic efficacy of the Epley canalith repositioning maneuver

OBJECTIVES/HYPOTHESES: The hypotheses of the current study are as follows: 1) That if the Epley canalith repositioning maneuver is an effective treatment for benign positional vertigo (BPV), relief from the vertigo should occur virtually immediately after the performance of the maneuver; 2) that the Epley canalith repositioning maneuver does provide almost immediate relief in BPV and should be the established treatment of choice for this disorder in both primary and tertiary care settings; and 3) that residual symptoms of lightheadedness and imbalance do persist after the resolution of the vertigo. The distinction of these symptoms from the vertigo is required for the accurate evaluation of the efficacy of positional maneuvers. STUDY DESIGN: Prospective cohort study in a tertiary care balance center. METHODS: Eighty-six patients (95 cases) with a history and physical examination consistent with active BPV were entered in the study. Patients were treated with a modified Epley canalith repositioning maneuver. A modified 360 degrees roll was used to treat those patients with horizontal canal BPV. Patients were provided with a preprinted diary in which they were to circle the answer most relevant to their symptoms for 14 days after the maneuver. Patients were then re-evaluated in the office at 2 weeks after the maneuver. RESULTS: The mean duration of the BPV before treatment was 9 weeks. Seventy-four percent of cases that were treated with one or two canalith repositioning maneuvers had a resolution of vertigo as a direct result of the maneuver. A resolution attributable to the first intervention was obtained in 70% of cases within 48 hours of the maneuver. An additional 14% of cases that were treated had a resolution of vertigo; however, it is not possible to say that these patients definitely benefited from the canalith repositioning maneuver. Only 4% of cases (three patients) manifested BPV that persisted after four treatments. Residual symptoms of lightheadedness or imbalance, or both, were frequent (47% of cases) but rarely required formal intervention with vestibular rehabilitation physical therapy. CONCLUSIONS: The Epley canalith repositioning maneuver results in a resolution of vertigo in the majority of patients (70% of cases) immediately after one treatment. It is safe and requires no special equipment or investigations. It should be established as the treatment of choice for BPV in both primary and tertiary care settings.     

良性阵发性位置性眩晕半规管结石复位中耳石的移位

中可以发生耳石的移位,仔细观察并正确识别眼震方向以及对治疗不佳者进行重新评价足发现耳石移位的关键.     

A randomized trial of the canalith repositioning procedure

OBJECTIVE: To compare the effectiveness and complications of our adaptation of the canalith repositioning procedure (CRP) with the expectation treatment for benign paroxysmal positional vertigo. STUDY DESIGN: A randomized, controlled trial in the setting of a neurotological clinic in Thailand. METHODS: Fifty-eight patients with posterior benign paroxysmal positional vertigo were randomly assigned to treatment and control groups using a block of four. The treatment group was treated with the modified CRP technique until the nystagmus disappeared. A mastoid oscillator was not used, nor were any instructions given for patients after the maneuver. Both groups recorded the daily grading of symptoms and the amount of anti-vertiginous drugs (cinnarizine) taken. Objective and subjective assessments were made weekly until the nystagmus disappeared or until 4 weeks had passed since treatment began. RESULTS: The rates of effectiveness of CRP treatment and the control treatment for benign paroxysmal positional vertigo were 75.9% and 48.2%, respectively. There was a significant difference in the treatment outcomes of the CRP and control groups (P =.03). The CRP group used significantly fewer drugs than the control group (P =.001). Complications in the CRP group, such as lateral canalithiasis and fainting, were observed in 13.8% of the patients. CONCLUSIONS: The CRP was more effective than the expectation treatment for benign paroxysmal positional vertigo insofar as it provided faster recovery and required less dependence on medication. Complications of CRP were limited to 13.8% of patients.     

上半规管良性阵发性位置性眩晕的诊断及治疗

目的探讨上半规管良性阵发性位置性眩晕（benign paroxysmal positional vertigo，BPPV）的诊断和治疗。方法回顾性分析了上半规管BPPV患者31例，并对所有患者采用管石复位法治疗后的效果进行评估。结果在Dix-Hallpike检查中，所有患者均诱发出垂直向下的眼震。22例（70．97％）患者一侧诱发出眼震，其中17例眼震伴有扭转成分，5例眼震不伴扭转成分。其余9例（29．03％）患者双侧诱发出现眼震，眼震伴有扭转成分的7例，其中2例眼震扭转方向指向同一侧，4例眼震的扭转方向不固定，1例患者仅一侧出现扭转成分。另外2例患者眼震不伴扭转成分。受累侧别明确诊断的19例（61．29％），其中11例为左侧上半规管受累，8例为右侧上半规管受累。受累侧别未明确诊断的12例（38．71％）。所有患者中，11例（35．48％）患者同时合并后半规管受累。对所有患者采取管石复位法治疗，21例（67．74％）痊愈，29例（93．55％）有效、2例（6．45％）无效。其中首次治愈14例（45．16％），平均治愈次数为1．71次。随访期间5例复发。结论上半规管BPPV临床中少见。在变位检查中，眼震的扭转成分较弱，临床中不易观察。在部分单侧上半规管BPPV患者中，双侧检查均能诱发眼震。管石复位法是治疗上半规管BPPV简单有效的手段。     

The effect of superior semicircular canal dehiscence on intracochlear sound pressures

Semicircular canal dehiscence (SCD) is a pathological opening in the bony wall of the inner ear that can result in conductive hearing loss. The hearing loss is variable across patients, and the precise mechanism and source of variability are not fully understood. Simultaneous measurements of basal intracochlear sound pressures in scala vestibuli (SV) and scala tympani (ST) enable quantification of the differential pressure across the cochlear partition, the stimulus that excites the cochlear partition. We used intracochlear sound pressure measurements in cadaveric preparations to study the effects of SCD size. Sound-induced pressures in SV and ST, as well as stapes velocity and ear canal pressure were measured simultaneously for various sizes of SCD followed by SCD patching. Our results showed that at low frequencies (<600 Hz), SCD decreased the pressure in both SV and ST, as well as differential pressure, and these effects became more pronounced as dehiscence size was increased. Near 100 Hz, SV decreased by about 10 dB for a 0.5-mm dehiscence and by 20 dB for a 2-mm dehiscence, while ST decreased by about 8 dB for a 0.5-mm dehiscence and by 18 dB for a 2-mm dehiscence. Differential pressure decreased by about 10 dB for a 0.5-mm dehiscence and by about 20 dB for a 2-mm dehiscence at 100 Hz. In some ears, for frequencies above 1 kHz, the smallest pinpoint dehiscence had bigger effects on the differential pressure (10-dB decrease) than larger dehiscences (less than 10-dB decrease), suggesting larger hearing losses in this frequency range. These effects due to SCD were reversible by patching the dehiscence. We also showed that under certain circumstances such as SCD, stapes velocity is not related to how the ear can transduce sound across the cochlear partition because it is not directly related to the differential pressure, emphasizing that certain pathologies cannot be fully assessed by measurements such as stapes velocity.