Patient scenario: A 53-year-old woman with hypoactive sexual desire disorder

Objective

To provide an expert review of the clinical management of hypoactive sexual desire disorder.

Method

The importance of diagnosing and providing therapeutic management for hypoactive sexual desire disorder will be explained with a case scenario which is resolved by drawing on original trial publications and meta-analyses published in English.

Results

Hypoactive sexual desire disorder (HSDD) is highly prevalent (9–16%) and has a strong impact on the quality of life of both women and their partners. Medical and sexual history, physical and laboratory examinations as well as validated questionnaires will help us make an accurate diagnosis. Treatment should begin by focusing on lifestyle and psychosexual therapy. Women randomized to oestrogen–testosterone transdermal patch combination or testosterone transdermal patch alone reported significantly increased frequency of satisfying sexual activity (p < 0.05). Hormonal treatment with oestrogen and testosterone or with testosterone alone should be personalised, as should follow-up.

Conclusions

Guidelines for the medical management of hypoactive sexual desire disorder are now available and this starts by understanding the importance of this disorder and knowing that accurate diagnosis and treatment options exist.     

A 59-year-old liver-transplanted woman with fever, dyspnea and pulmonary infiltrates

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An 89-year-old patient with acquired murmur associated with pulmonary embolism

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A 71-year-old woman with psp-like symptoms

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A 64-year-old woman with progressive dementia and leukoencephalopathy

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