中草药贴膏防治疤痕增殖实验与临床的观察

目的探讨用中草药贴膏防治疤痕增殖疗效。方法用中草药贴膏治疗疤痕增生和疤痕疙瘩患共１５２例。结果从临床应用中提示疗效与创面愈合后开始治疗的早晚有关,前组显效率７３．６８％,后组显效率４１．４％。结论早期治疗,伤口处于修复过程高峰,纤维组织的胚胎性强,有利于抑制疤痕增生。     

仙冰疤痕膏配合护膜治疗增生性疤痕取得新进展

目的：使用仙冰疤痕膏外贴护膜治疗增生性疤痕，观察其治疗效果。方法：将22例增生性疤痕患者随机分两组，分别用仙冰疤痕膏外贴护膜和常规外用美宝疤痕平治疗。结果：仙冰疤痕膏外贴护膜组与外用美宝疤痕平常规治疗组相比，显效时间及3个月显效率有显著差异。结论：仙冰疤痕膏外加护膜治疗增生性疤痕取得进展。     

3种方法在治疗烧伤后增生性疤痕的疗效比较

目的探讨治疗增生性疤痕的有效方法。方法将90例烧伤后增生性疤痕患者按就诊次序随机分为压力法、外用疤痕贴法和压力外用疤痕贴联合法3组,每组各30例。比较治疗20d后3组患者疤痕厚度情况。结果3组患者治疗20d后疤痕厚度比较,经统计学分析,均P〈0．05,差异有统计学意义。采用联合治疗方法后,患者的疤痕最薄,外用疤痕贴组其次,压力组最厚。结论压力外用疤痕贴联合法对治疗增生性疤痕的疗效最强。     

湿润烫伤膏联合美宝疤痕平对烧烫伤增生性瘢痕的疗效分析

目的观察美宝疤痕平对烧烫伤后增生性瘢痕的防治作用,分析其治疗机制。方法对烧伤后伴有刺痛和瘙痒症状增生性瘢痕患者126例,分为治疗组65例,对照组61例,两组患者均采用湿润烧伤膏(MEBO)治疗,治疗组在此基础上加用美宝疤痕平治疗,用药后随时观察瘙痒症状,用药1,2个月观察瘢痕硬度和颜色及受损关节的活动功能。结果治疗组65例患者的优良率73.84%,关节活动功能达正常范围的46例,对照组61例患者的优良率60.64%,关节活动功能达正常范围的32例,两组间的优良率和关节功能恢复情况有明显差异。结论湿润烫伤膏联合美宝疤痕平治疗烧烫伤增生性瘢痕疗效确切,受损关节功能恢复良好,具有较好的防治作用。     

MiraDry治疗腋臭的疗效观察及护理

总结了皮肤外科门诊采用MiraDry微波治疗仪治疗的10例腋臭患者的疗效及护理经验。本组患者中共10例患者,治愈8例,显效2例,治愈率达80%,有效率达100%,且患者满意度高,并发症少,疤痕增生率低。认为MiraDry治疗腋臭的方法效果较好,是治疗腋臭的理想方法。     

物理疗法结合中成药治疗乳腺小叶增生疗效观察

目的探讨物理疗法结合中成药治疗乳腺小叶增生的临床疗效.方法将确诊为乳腺小叶增生患者随机分成治疗组和对照组.治疗组60例口服乳癖消片外加每日1次淋浴,同时用热水喷头对增生的乳房持续淋2～3 min;对照A组60例单纯口服乳癖消片;对照B组不用全身淋浴只是对增生的乳房局部热敷10 min.结果治疗组有效率96.67%,痊愈率63.33%;对照A组有效率95%,痊愈率43.33%;对照B组有效率71.67%,痊愈率21.67%.结论物理疗法结合中成药治疗乳腺小叶增生有显著疗效.     

加用复方黄柏液灌肠治疗溃疡性结肠炎的疗效

目的 探讨溃疡性结肠炎(VC)治疗中加用复方黄柏液灌肠的临床疗效.方法 选择VC活动期患者36例,按随机数字表法分为治疗组、对照组2组,每组18例.在对照组西医内科基础治疗的基础上,治疗组加用复方黄柏液灌肠.结果 治疗组的显效率为72.3%,对照组的显效率为44.4%,2组比较差异有统计学意义(P＜0.05).结论 在对VC治疗中加用复方黄柏液灌肠疗效确切.     

达立通颗粒治疗痞满证(功能性消化不良)的随机对照双盲试验

目的评价达立通颗粒治疗痞满证(功能性消化不良)的疗效和安全性.方法根据本研究的纳入与排出标准,选取痞满证(功能性消化不良)患者120例,按3:1随机分为达立通颗粒组(治疗组)90例和西沙必利组(对照组)30例,进行随机对照双盲双模拟试验.治疗组口服达立通颗粒,每日3次,每次6 g;对照组口服西沙必利片,每日3次,每次5 mg,疗程均为2周.结果对中医证候疗效而言,意向性治疗(intention-to-treat,ITT)分析结果显示,治疗组总显效率62.37%,总有效率99.55%;对照组总显效率58.08%,总有效率90.33%.符合方案数据分析(per-protocol population,PP)结果显示,治疗组总显效率为64.45%,总有效率96.67%;对照组总显效率为60.00%,总有效率为93.33%.两组中医证候疗效比较无统计学意义(P＞0.05).对痞满证候疗效而言,ITT分析显示,治疗组总显效率53.76%,总有效率86.02%;对照组的总显效率48.38%,总有效率80.64%.PP分析显示治疗组的总显效率55.56%,总有效率88.89%;对照组总显效率50.00%,总有效率为83.33%.两组痞满证疗效比较无统计学意义(P＞0.05).胃排空试验(PP人群)显示,治疗组总显效率72.42%,总有效率为79.32%;对照组显效率64.28%,总有效率64.28%.两组比较无统计学意义(P＞0.05).ITT分析与PP分析结果一致.临床观察中未发现明显不良反应.结论达立通颗粒疗效与西沙必利相当,未发现明显的毒副作用.     

溶栓合剂治疗急性脑梗死的临床疗效观察

目的:观察溶栓合剂治疗急性脑梗死的临床疗效.方法:选择具有溶栓指征的急性脑梗死患者88例,按随机数字表法分为治疗组与对照组,治疗组用溶栓合剂治疗,对照组仅用尿激酶治疗,两组患者的其他常规辅助治疗方法相同,观察其临床疗效以及神经功能缺损评分的变化.结果:治疗组总显效率为67.9%,总有效率为85.7%;对照组总显效率为31.3%,总有效率为68.8%;两组比较均有显著性差异(P<0.01和P<0.05).治疗后治疗组神经功能缺损评分显著降低,显著优于对照组(P<0.01).结论:溶栓合剂治疗急性脑梗死疗效优于单纯尿激酶,可促进神经功能恢复,安全性高,能降低脑出血发生率.     

奥曲肽治疗肝硬化食管胃底静脉曲张破裂出血疗效观察

目的 观察奥曲肽治疗肝硬化食管胃底静脉曲张破裂出血的疗效.方法 86例肝硬化食管胃底静脉曲张破裂出血患者,随机分为三组,分别应用奥曲肽(1组,30例)、垂体后叶素(2组,28例)、奥曲肽+垂体后叶素(3组,28例)进行治疗.结果 1组治疗显效率73.3%,总有效率93.3%;2组治疗显效率39.3%,总有效率67.9%;3组治疗显效率75.0%,总有效率92.9%;其中1组、3组明显高于2组(P＜0.05),但1组与3组比较无差别.结论 奥曲肽治疗肝硬化食管胃底静脉曲张破裂出血安全有效,联合应用垂体后叶素并不能提高疗效.     

缝合固定法延长静脉套管针留置时间的临床研究

目的：比较不同固定方法延长静脉套管针留置时间，以确保大面积烧伤患在休克期的抢救成功率。方法：采用美国B－D公司出品的以Vialon为材料制成的静脉套管留置针，将40名烧伤面积在40％以上的患分成对照、实验二组，分别给予粘贴膜及缝合固定加粘贴膜固定。结果：常规基础上应用加固缝合的方法，减少了导管滑脱的机会，使静脉套管针留置时间明显延长。结论：应用静脉套管针加缝合固定既可保护患的血管、减轻痛苦，又保证了有效的输液通道。     

医用橡皮膏牵引固定前列腺摘除术后气囊导尿管的效果观察

[目的]观察医用橡皮膏牵引固定前列腺摘除术后气囊导尿管的效果。[方法]将124例前列腺摘除术后病人随机分成实验组和对照组各62例,分别采用医用橡皮膏和纱布牵引固定气囊导尿管。观察术后气囊导尿管固定的稳定性及病人体温变化、出血情况、膀胱持续冲洗的时间、冲洗液的量、疼痛不适感等。[结果]采用医用橡皮膏牵引固定明显优于纱布牵引固定法。医用橡皮膏牵引固定法病人术后出血量少,体温变化多为中等热,持续时间短,膀胱持续冲洗时间短,冲洗量少,疼痛不适感减轻,两组比较有统计学意义(P<0.05)。[结论]医用橡皮膏牵引固定气囊导尿管是一种较好的方法。     

Indian herbs and herbal drugs used for the treatment of diabetes

Traditional Medicines derived from medicinal plants are used by about 60% of the world's population. This review focuses on Indian Herbal drugs and plants used in the treatment of diabetes, especially in India. Diabetes is an important human ailment afflicting many from various walks of life in different countries. In India it is proving to be a major health problem, especially in the urban areas. Though there are various approaches to reduce the ill effects of diabetes and its secondary complications, herbal formulations are preferred due to lesser side effects and low cost. A list of medicinal plants with proven antidiabetic and related beneficial effects and of herbal drugs used in treatment of diabetes is compiled. These include, Allium sativum, Eugenia jambolana, Momordica charantia Ocimum sanctum, Phyllanthus amarus, Pterocarpus marsupium, Tinospora cordifolia, Trigonella foenum graecum and Withania somnifera. One of the etiologic factors implicated in the development of diabetes and its complications is the damage induced by free radicals and hence an antidiabetic compound with antioxidant properties would be more beneficial. Therefore information on antioxidant effects of these medicinal plants is also included.     

单向中频电加助透液防治瘢痕增生

为防治瘢痕增生，寻求有效治疗方法，我们采用单向中频电加助透液治疗瘢痕增生患者３３例，痊愈显效率为６４％，总有效率为８８％。结果表明，单向中频电加助透液能增强导入作用，是防治瘢痕增生的有效方法。     

A technique for control of hypertrophic scarring in the central region of the face

Various methods are available for applying pressure to the central portion of the face to reduce hypertrophic scarring after burn injury. Our center uses an elastomer insert with a thermoplastic backing, which is formed over a plaster mold of the patient's face. The insert is worn under a traditional anti-burn scar face mask. We reviewed the records of 26 patients with hypertrophic scarring to the central portion of the face to assess the effectiveness of the insert. Seventeen (65%) of these patients wore the insert until scar maturation. Three of these 17 patients later required reconstructive surgery of the central face. Our findings suggest that pressure to this part of the face may be effective in decreasing hypertrophic scar formation. The insert described in this article is inexpensive and relatively easy to fabricate.     

动静脉内瘘及静脉2种固定方法临床应用的比较

目的探讨血液透析过程中选择合适的动静脉内瘘及静脉穿刺针固定方法,以减少血液透析过程中动静脉内瘘及静脉穿刺针眼渗血、滑针、血肿等并发症的发生。方法选择在血液净化中心行维持性血液透析,伴有动脉压i岛、糖尿病,透析过程中易发生渗血、滑针、血肿并发症的老年患者16例,将患者进行自身对照,先后采用常规胶布固定法和常规胶布加弹力绷带固定法。每人每种方法各观察3个月624次,共1248次由专职透析护士按标准化操作。比较2组透析过程渗血、滑针、血肿的发生率。结果常规固定法并发症发生率为7．21％,常规加绷带固定法渗血、滑针、血肿并发症发生率为144％,2组比较差异有统计学意义（P〈0．01）。结论常规加绷带固定法能有效预防透析过程动静脉内瘘和静脉渗血、滑针、血肿等并发症,减少血管损伤,操作简便,能显著减少护理工作量和医疗成本,提高患者的满意度。     

爱尔碘外擦治疗婴幼儿头皮胶布过敏的疗效观察与护理

目的：观察爱尔碘皮肤消毒液外擦治疗胶布致婴幼儿头皮局部皮肤过敏的效果。方法：对65例胶布致头皮局部皮肤过敏婴幼儿外科擦爱尔碘皮肤消毒液,每日2—3次,连续3-4d。结果：爱尔碘皮肤消毒液外擦对胶布致婴幼儿头皮局部皮肤过敏有较好的治疗效果。结论：使用爱尔碘皮肤消毒液外擦治疗胶布致婴幼儿头皮局部皮肤过敏是一种安全、有效、操作简单、经济实惠的治疗方法。     

Early repairing with full thickness skin graft and postoperational rehabilitation treatment of deep burn of hand

Background: To deep burn of hand,Some adopted natural healing,some adopted removal of eschar,thin and intermediate thickness skin flap repairing,But after healing,proliferation and contracture of scar of pigmentation,obvious dryness,no brightness,had elasticity often appeared that would reduce tolerance of abrade and impair function and appearnce of fingers.Objective: To investigate the clinical effect of full thickness skin graft after removal of eschar on deep burn of hand.Unit:169th Hospital of PLA.Subjects: 36 cases of deep burn of hand were investigated including 28 males,8 females,aged 2-46 years old among which were 24 cases of flame burn,6 cases of scald,3 cases of acid burn,2 cases of alkali burn with 8 cases at both hands,3 cases at both palm and dorsum of hand.Intervention:(1)After 6-8d,when edema disappeared,routine therapy was adopted to circular eschar,relief incision;One day before operation,wet packing with antibiotics and bandaging was adopted to achieve relative asepsis circummstance.(2) 0.5 before operatioin,surface of wound was brushed completely,hibitane soaking for 30 min complex iodine sterilizing operation region.(3)Eschar was removed under tourniquet.Necrosed tissue was deleted completely,avoiding injuring vessels (if longe quantity of bone substance was exposed,transferred to other method;After complet hemostasis,wet packing with saline containing antibiotics for 10 min.(4) Full thickness skinflap was reilled to keep apporiate tension.After suture subcutaneous stasis of blood was irrigated;Skin flap was pressed with bits of ganze and compression bandage.Finger and wrist were fixed with plaster support.(5) Antibiotics was used systemicly;Operation part was elevated and stitches were removed after 10d.Movement was started from 15-20d,and increased successively.Result:Wound surface of all cases healed within 25d,survival rate of skin flap was over 95%.After 0.5-1 year of follow-up,no obvious proliferation and spasm of scar and dysfunction were found,outward appearance of hand,elasticity,brightness and abrade tolerance approached normal level.Conclusion: Early full thickness skin graft could promote healing of wound surface in deep burn of hand and decrease incidence of dysfunction leaded by proliferation and spasm of scar.     

康复新液湿敷与安普贴外敷治疗压疮的疗效观察

目的对比康复新液湿敷与安普贴外敷治疗压疮的疗效，观察康复新液湿敷治疗压疮的临床治疗效果。方法76例压疮患者分为康复新组和安普贴组。康复新组采用康复新液湿敷法，每日换药2～3次，安普贴组采用安普贴外敷法，每周更换敷料2次。观察疗效。结果2组治疗均能促进压疮愈合，治疗21d后康复新组压疮分泌物消失44倒（70．97％），结痂38例（61．29％），总有效率95．16％；安普贴组分别为27例（51．92％），21例（40．36％），总有效率73．08％。2组疗效有显著性差异。结论康复新液湿敷法和安普贴外敷法均能促进压疮的创面愈合，缩短创面愈合时间，且康复新的疗效更佳。     

A型肉毒毒素可抑制人增生性瘢痕成纤维细胞增殖和胶原蛋白的合成

背景:A型肉毒毒素伤口周围局部注射可以减少瘢痕的形成,而且对瘢痕的增生挛缩有抑制作用,可以促进瘢痕的萎缩变平。目的:观察A型肉毒毒素对人增生性瘢痕成纤维细胞的增殖和胶原蛋白合成的影响。方法:体外分离、培养人增生性瘢痕成纤维细胞,取对数生长期的细胞接种培养,使用稀释浓度为0.1U/LA型肉毒素DMEM细胞培养基对细胞的生长过程进行干扰,对照组以含胎牛血清的DMEM培养基培养。结果与结论:细胞接种第1～15天,对照组可见梭形的增生性瘢痕成纤维细胞分裂增殖,局部融合成细胞单层,细胞生长旺盛,细胞排列呈现高度一致性。A型肉毒毒素组细胞增殖速度慢,细胞数量少,细胞排列方向散乱,A型肉毒毒素组细胞数为对照组细胞数的79.3%,A型肉毒毒素实验组胶原蛋白合成量为正常对照组的48.4%,差异有显著性意义(P<0.05)。提示A型肉毒毒素可以抑制人增生性瘢痕成纤维细胞的增殖以及胶原蛋白的合成。