An in vitro platform supports generation of human innate lymphoid cells from CD34+ hematopoietic progenitors that recapitulate ex vivo identity

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Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers

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Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells

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A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut

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Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response

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Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes

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BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen

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Follicular lymphoma triggers phenotypic and functional remodeling of the human lymphoid stromal cell landscape

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Newly recruited intraepithelial Ly6A+CCR9+CD4+ T cells protect against enteric viral infection

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Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation

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Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer

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SARS-CoV-2-specific T cell memory with common TCRαβ motifs is established in unvaccinated children who seroconvert after infection

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Differential regulation of transcription factor T-bet induction during NK cell development and T helper-1 cell differentiation

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Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling

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Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection

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Lipids regulate peripheral serotonin release via gut CD1d

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Human Memory B Cells Harbor Diverse Cross-Neutralizing Antibodies against BK and JC Polyomaviruses

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Chronic calcium signaling in IgE+ B cells limits plasma cell differentiation and survival

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Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses

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Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

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