无缝隙护理在老年高血压患者临床护理中的应用及对生存质量的影响

目的:探究无缝隙护理在老年高血压患者临床护理中的应用及对生存质量的影响。方法:选取2017年2月-2019年2月本院收治老年高血压136例,按随机数字表法分为研究组与对照组,各68例。对照组给予常规性临床护理手段,研究组在对照组基础上采用无缝隙护理模式。观察比较两组护理前后血压水平变化情况、生存质量与护理满意度。结果:护理前两组收缩压与舒张压比较,差异均无统计学意义(P0.05);护理后研究组收缩压与舒张压均低于对照组(P0.05)。护理前两组生存质量比较,差异无统计学意义(P0.05);护理后研究组生活质量优于对照组(P0.05)。研究组护理满意度优于对照组(P0.05)。结论:采用无缝隙护理模式能有效降低老年高血压患者的血压,增强临床护理依从性,提升其生存质量以及临床护理满意度,值得广泛应用以及更深层次的研究。     

中老年高血压患者进行护理干预的效果分析

目的分析在中老年高血压患者中实施护理干预的临床效果。方法选取2015年9月至2017年6月在我院治疗高血压病症的中老年患者78例,按照随机数字表法随机分为常规组和护理组各39例,常规组实施一般常规基础护理方法,护理组患者实施护理干预方法,观察两组患者的血压收缩压、舒张压变化情况以及护理满意度。结果护理组患者的血压收缩压、舒张压指标均显著低于常规组(P0.05);且其护理满意度较之常规组差异明显(P0.05)。结论在中老年高血压患者中实施护理干预能够取得理想的血压控制效果,显著提高了患者的生活质量。     

社区护理干预在老年高血压患者中的应用效果

目的探究社区护理干预在老年高血压患者中的应用效果。方法选择2014年3月至2015年1月于我院出院54例老年高血压患者作为研究对象,随机分为观察组与对照组,各27例。对照组患者进行常规护理;观察组患者于对照组基础上予以社区护理干预。观察两组患者血压变化、生活质量。结果观察组与对照组患者干预前收缩压与舒张压相比,差异无统计学意义(P0.05);干预后,对照组患者收缩压与舒张压均高于观察组,差异有统计学意义(P0.05);观察组患者干预后生活质量评分显著高于对照组,差异有统计学意义(P0.05)。结论社区护理干预可有效控制老年高血压患者的血压,且能提高其生活质量,值得推广运用     

综合护理干预在高血压合并冠心病患者护理中的应用效果分析

目的:探讨综合护理干预措施应用在高血压合并冠心病患者对血压和生活质量的影响。方法:选择我院治疗的高血压合并冠心病患者110例作为研究对象,采取随机数字表法分为观察组和对照组,每组各55例,对照组给予常规护理,观察组采取综合护理干预,观察两组护理情况。结果:观察组干预后舒张压和收缩压降低优于对照组,组间对比差异具有统计学意义(P0.05)。观察组干预后患者生后质量评分各维度和总分均高于对照组,组间对比差异具有统计学意义(P0.05)。结论:综合护理干预措施应用在高血压合并冠心病患者可以改善患者血压,提高患者生活质量,值得在临床上大力推广使用。     

Roy适应模式在老年原发性高血压患者护理中的应用

目的探讨Roy适应模式在老年原发性高血压(PH)患者护理中的应用效果。方法选取镇平县中医院2015年3月至2017年3月收治的77例老年PH患者,按照随机数表法分为对照组38例(接受常规护理)和观察组39例(接受Roy适应模式的护理)和比较两组干预前后舒张压、收缩压变化情况及生活质量(QOL)评分、护理满意度。结果干预后观察组收缩压及舒张压均低于对照组,QOL评分及护理满意度均高于对照组,差异有统计学意义(P均<0.05)。结论 Roy适应模式可改善老年PH患者生活质量,控制其血压水平,提高其护理满意度。     

社区老年高血压患者的临床护理要点研究

目的:研究分析对社区老年高血压患者进行护理干预的临床效果。方法:选择本社区2014年6月至2016年6月接受治疗的老年高血压患者182例作为研究对象,按照随机数字抽取表法将患者分为两组,观察组和对照组均为91例,其中对照组患者采用高血压常规护理措施,给予观察组患者在常规护理的基础上,依据患者病史和临床特征制定针对性护理方案,比较实施护理服务后两组患者的血压控制情况、生活质量评分等。结果:观察组患者舒张压与收缩压均明显低于对照组,比较差异具有统计学意义(P0.05);观察组生活质量综合评分显著高于对照组,比较差异具有统计学意义(P0.05)。结论:给予社区老年高血压患者采用针对性护理干预措施能够降低患者的血压,改善患者生活质量,具有重要的临床意义。     

个体化护理对老年高血压的临床影响观察

目的:探讨个体化护理对老年高血压(HBP)患者的积极影响。方法:选择我院80例老年高血压患者,应用随机数字表将其分为实验组(n=40)及对照组(n=40),分别应用个体化护理、常规护理;对比两组血压水平及护理满意度。结果:干预后,实验组舒张压、收缩压均显著低于对照组(P0.05)。实验组护理满意度达97.50%,明显高于对照组85.00%(P0.05)。结论:个体化护理可有效改善老年高血压患者血压水平,提高患者满意度。     

老年高血压患者的生活护理及对患者收缩压、舒张压的影响

目的:探究老年高血压患者生活护理干预效果以及对收缩压和舒张压的影响。方法:选取本院在2017年1-12月收治的老年高血压患者118例,按照随机数字表法将其分为研究组和对照组,各59例。研究组采用生活护理干预,对照组采用常规护理。比较两组患者的治疗依从性(按医嘱用药、采纳健康生活方式)以及血压情况。结果:研究组谨遵医嘱用药情况为84.75%、健康生活方式采纳情况为93.22%,均明显高于对照组的50.85%和67.80%,差异均有统计学意义(P0.05)。两组患者护理前的舒张压、收缩压比较,差异均无统计学意义(P0.05);护理干预后,研究组的收缩压、舒张压均低于对照组,差异均有统计学意义(P0.05)。护理干预后,研究组血压正常率为88.14%,明显高于对照组的67.80%,差异有统计学意义(x~2=4.012,P0.05)。结论:在治疗老年高血压时,采取生活护理干预效果好,值得在临床上推广。     

个体化护理对老年高血压患者血压及并发症的影响

目的观察个体化护理对老年高血压患者血压及并发症的影响。方法本次选取我院2014年6月至2016年6月住院部收治的老年高血压患者120例,根据护理方式的不同分为两组,观察组60例(个体化护理)、对照组60例(常规护理);观察组两组患者的血压、心率、护理满意度。结果观察组患者的血压(收缩压145.12±3.02mm Hg、舒张压78.25±1.07mm Hg)、心率(76.82±1.02次/min)低于对照组(P0.05);且观察组患者的护理满意度95.00%与对照组比较,观察组明显处于优势(P0.05)。结论在临床上对老年高血压患者血压及并发症应用个体化护理措施,可以有效的帮助患者改善血压状况,从而使其水平稳定,减少并发症,提高生活质量,值得推广和应用。     

门诊老年高血压患者的综合护理效果研究

目的研究门诊老年高血压患者的综合护理效果。方法选取我院2012年1月至2017年1月门诊收治的300例老年高血压患者为研究对象,根据电脑抽签的方式分为观察组与对照组,各150例,对照组接受常规护理方式,观察组接受综合护理方式,观察两组患者临床护理效果。结果护理后观察组患者收缩压水平为(135.36±10.25)mm Hg,对照组为(145.36±12.27)mm Hg;舒张压为(80.22±5.54)mm Hg、对照组为(89.58±5.69)mm Hg,观察组血压改善水平显著优于对照组,P0.05,差异有统计学意义;综合满意度显著高于对照组,P0.05,差异有统计学意义。结论综合护理应用于门诊老年高血压患者疗效显著,能够有效巩固临床治疗效果,改善血压水平,提升满意度,值得推广。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.