复方沙棘籽油栓治疗宫颈糜烂的临床观察

20 0 2年 1月至 2 0 0 3年 1月我院用复方沙棘籽油栓治疗宫颈糜烂 ,疗效明显 ,报告如下。1　资料与方法1.1　临床资料　近 3个月未接受过其它治疗自愿接受药物治疗者 196例 ,18～ 5 5岁 ,均有性生活史 ,行宫颈刮片排除癌变 ,阴道分泌物涂片排除滴虫、念珠菌感染。根据糜烂面积分为轻、中、重 3度 ,根据糜烂深浅度分为 3型 ,即单纯型、颗粒型、乳头型。本组病例分类、分型见表 1。表 1　 196例宫颈糜烂的分类、分型 (n)分类单纯型颗粒型乳头型合计轻度 32 110 4 3中度 4 2 5 6 4 10 2重度 5 3412 5 1合计 7910 116 1961.2　给药方法　复方沙…     

复方沙棘籽油栓治疗宫颈HPV感染的临床观察

目的探讨复方沙棘籽油栓治疗宫颈高危型HPV感染的有效性。方法收集2011年11月至2012年12月在北京大学第一医院妇产科门诊就诊的宫颈高危型HPV感染患者152例,按随机数字表将患者分为两组,研究组（102例）采用复方沙棘籽油栓治疗3个月,对照组（50例）不用药。两组患者分别在用药后第3周和第16周进行宫颈液基细胞学（TCT）和高危型HPV检测。结果①152例患者中,高危型HPV感染的检出率依次为HPV16型55例（36．2％）,HPV58型34例（22．4％）,HPV52型26例（17．1％）,HPV53型19例（12．5％）,HPV56型14例（9．2％）,HPV33型13例（8．5％）,HPV39型8例（5．3％）,HPV18型7例（4．6％）;两型及以上感染24例（15．8％）②研究组用药后第16周HPV的清除率为86．5％（83／96）,对照组为57．4％（27／47）,两组比较,差异有统计学意义（P〈0．01）,两组宫颈细胞学转阴率分别为93．5％（29／31）和73．3％（11／15）,两组比较,差异有统计学意义（P〈0．05）;③研究组患者在用药期间无不良反应。结论复方沙棘籽油栓对宫颈单纯高危型HPV感染的清除安全有效。     

复方甲硝唑阴道栓治疗细菌性阴道炎的效果观察

目的 观察比较甲硝唑片与复方甲硝唑阴道栓治疗细菌性阴道炎的临床效果。方法 选取80例细菌性阴道炎患者,应用机械抽样法分为对照组与试验组,每组40例。在与伴侣同时服用甲硝唑片的基础上,对照组采取甲硝唑片治疗,试验组采取复方甲硝唑阴道栓治疗,均采用阴道穹窿处给药。比较两组患者的治疗效果及治疗前后阴道健康指数评分（VHIS）评分和Nugent评分。结果 试验组治疗总有效率为97.5%,显著高于对照组的80.0%,差异有统计学意义（P<0.05）。治疗前,两组VHIS评分和Nugent评分比较,差异无统计学意义（P>0.05）;治疗后,试验组VHIS评分高于对照组,Nugent评分低于对照组,差异有统计学意义（P<0.05）。结论 复方甲硝唑阴道栓治疗细菌性阴道炎患者,可显著改善阴道健康情况,疗效显著,值得临床推广与应用。     

复方沙棘籽油栓联合蛇床子散治疗阴道炎疗效观察

目的探讨复方沙棘籽油栓联合蛇床子散治疗湿热型阴道炎的疗效。方法选择我院门诊湿热型阴道炎患者90例,其中滴虫阴道炎40例,外阴道假丝酵母菌病50例,采用蛇床子散煎汤坐浴后复方沙棘籽油栓阴道纳药,10天为1个疗程,1个疗程结束后观察疗效。结果复方沙棘籽油栓联合蛇床子散煎汤坐浴治疗湿热型阴道炎,两组治愈率及总有效率与常规的治疗方案相近,并且复发率低。结论复方沙棘籽油栓联合蛇床子散可以在湿热型滴虫阴道炎、外阴道假丝酵母菌病的治疗中推广应用。     

达克宁栓治疗霉菌性阴道炎的疗效分析

目的：探讨迭克宁栓治疗霉菌性阴道炎的临床疗效。方法：选取我院在2010年01月到2013年01月收治的110例霉菌性阴道炎患者随机分为对照组和观察组,对照组患者使用克霉唑栓进行治疗,观察组患者使用达克宁栓进行治疗。结果：对照组临床疗效总有效率为85．5％,观察组临床疗效总有效率为96．4％,两组在临床疗效上存在的差异性具有统计学意义（P〈0．05）;观察组患者经过治疗复发率明显低于对照组（P〈0．05）。结论：达克宁栓治疗霉菌性阴道炎取得的临床疗效显著,具有安全、可靠性。     

复方沙棘籽油栓治疗外阴硬化性苔藓的疗效观察

目的分析复方沙棘籽油栓治疗女性外阴硬化性苔藓的疗效。方法选取2013年8月~2015年8月我院收治的外阴硬化性苔藓患者116例为研究对象,将其随机分为治疗组和对照组,各58例。治疗组采用复方沙棘籽油栓治疗,对照组采用0.3%黄体酮油膏治疗。连用60天后,观察两组患者的疗效。结果治疗组总有效率、痊愈率均显著高于对照组,且治疗组复发率低于对照组,差异均有统计学意义(P0.05)。结论复方沙棘籽油栓治疗外阴硬化性苔藓,疗效显著,复发率低,值得临床推广。     

达克宁栓治疗妊娠期念珠菌性阴道炎60例疗效分析

妊娠期的特殊生理变化使念珠菌性阴道炎的发病率明显升高 ,易复发 ,且难以根治 ,在临床治疗中更要注意药物对胎儿的影响。我院门诊应用达克宁栓治疗妊娠期念珠菌性阴道炎 6 0例取得了良好的临床效果 ,现报道如下。1　资料与方法1 1　一般资料　　 1998年 3月至 1999年 3月在我院门诊就诊的妊娠期念珠菌性阴道炎的妇女 6 0例 ,年龄 2 0～ 36岁 ,平均 2 8岁 ,妊娠 12～ 33周 ,有外阴瘙痒、烧灼感、肿胀 ,白带增多 ,排尿时烧灼感等症状 ,妇科检查发现小阴唇内侧及阴道粘膜被覆白色膜状物 ,白带粘稠、呈豆渣状或凝乳样 ,局部充血、湿疹、糜烂或…     

氧氟沙星栓治疗细菌性阴道炎临床效果评价

氧氟沙星栓（ｏｆｌｏｘａｃｉｎｓｕｐｐｏｓｉｔｏｒｙＯＦＳ）是新喹诺酮（ｎｅｗｑｕｉｎｏｋｅｔｏｎｅ）类广谱抗菌药，正式药名为氟嗪酸（ｎｏｒｆｌｏｐａｃｉｎ），该药抗菌谱广，抗菌作用强，抗革兰氏阳性菌的活性大于氟哌酸（ｎｏｒｆｌｏｘａｃｉｎ）４～８倍...     

妊马雌酮联合复方莪术油栓治疗复发性老年性阴道炎和尿道炎临床观察

目的:观察低剂量妊马雌酮联合复方莪术油栓治疗复发性老年性阴道炎和尿道炎疗效.方法:62例复发性老年性阴道炎和尿道炎患者,用药前后自身对照研究.结果:62例患者用药后,阴道炎、尿道炎症状显著改善.血清FSH水平显著下降,E2水平上升至卵泡早期水平(P＜0.05).用药后体重、子宫内膜厚度较用药前无显著变化.结论:低剂量妊马雌酮联合复方莪术油栓能有效改善阴道及尿道的健康状态.无内膜过度刺激.     

达克宁栓治疗妊娠期念珠菌性阴道炎60例疗效分析

念珠菌性阴道炎是较常见的阴道炎，其发病率仅次于滴虫性阴道炎。妊娠期的特殊生理变化使念珠菌性阴道炎的发病率明显升高，易复发，且难以根治。孕妇在妊娠期间特别是在妊娠中、晚期罹患念珠菌性阴道炎，是常见的妊娠合并症，其发病率约为15％，而非孕妇女的发病率不足5％，可见妊娠是念珠菌性阴道炎的易发因素。为了胎儿的绝对安全，在临床治疗中更要注意药物对胎儿的影响。     

The effect of amniotic fluid on bacterial growth in three population groups

Eighty-five amniotic fluid specimens from women of three racial groups in the third trimester of pregnancy were each tested for antibacterial activity against Escherichia coli, Staphylococcus aureus, Proteus mirabilis, Streptococcus faecalis, and Candida albicans. Seventy-six per cent of fluid samples from white patients were inhibitory, while the corresponding figures for Africans and Indians were 33 and 52, respectively. Of 19 African fluid samples tested against E. coli only, one proved inhibitory.     

The effect of ylang oil and lemon oil inhalation on labor pain and anxiety pregnant women: A randomized controlled trial

Backgroundand purpose: To date, there has been very limited experimental research on the impact of ylang ylang oil and lemon oil inhalation labor pain. This study was conducted to investigate the effects of aromatherapy, one of the non-pharmacological pain methods, on anxiety and labor pain in the active phase in primiparous pregnant women.MethodsA randomized controlled trial design was used in the study, which was conducted with 45 primiparous pregnant women. Volunteers were randomized into the lemon oil group (n = 15), ylang-ylang oil group (n = 15), and control group (n = 15) by using the sealed envelope method. The visual analog scale (VAS) and the state anxiety inventory were applied to the intervention and control groups before the application. After the application, the VAS and the state anxiety inventory were applied at 5–7 cm dilatation and the VAS was applied alone at 8–10 cm dilatation. The trait anxiety inventory was applied to the volunteers after delivery.ResultsThe mean pain scores at 5–7 cm dilatation in the intervention groups (lemon oil 6.90, ylang ylang oil, 7.30) were significantly lower than in the control group (9.20) (p = 0.005). There was no significant difference between the groups in terms of their mean pre-intervention and 5-7-cm-dilatation anxiety scores (p = 0.750; p = 0.663), mean trait anxiety scores (p = 0.094), and mean first-and fifth-minute Apgar scores (p = 0.051; p = 0.051).ConclusionIt was found that aromatherapy applied by inhalation at labor reduced the perception of labor pain but had no effect on anxiety.     

The effect of aromatherapy with peppermint essential oil on anxiety of cardiac patients in emergency department: A placebo-controlled study

IntroductionAnxiety is an unpleasant feeling that increases the myocardial oxygen demand in acute coronary syndrome. This study aimed to evaluate the effect of peppermint aromatherapy on anxiety in patients with acute coronary syndrome in the emergency department.Materials and methodsIn this clinical trial study, 64 patients with acute coronary syndrome were randomly divided into intervention and control groups. In the intervention group, a cotton ball was soaked in 100% peppermint essential oil and placed about 20 cm from the patient's nose for 1 h while in the control group, the cotton ball was soaked in water. Anxiety was measured before and after the intervention with The Spielberger state-trait anxiety inventory. The data were analyzed in SPSS ver.23 software.ResultsNo significant difference was observed between the two groups in terms of patients’ demographic data. The mean score of trait and state anxiety before the intervention was not significantly different between the two groups. After the intervention, anxiety was significantly lower in the intervention group (37.72 ± 10.41) compared to the control group (42.62 ± 5.99) (P = 0.021). Results indicated a significant decrease in anxiety after the intervention (P < 0.001) in the intervention group. Such a difference was not significant in the control group.ConclusionPeppermint essential oil inhalation significantly reduces anxiety of patients with acute coronary syndrome in emergency department.     

The effect of Aloe vera gel and sweet almond oil on striae gravidarum in nulliparous women

Background and objective: Striae are linear depressions of the skin and causes psychological and sexual problems in person. Different methods are used to prevent and treat them but there is no definitive method. We compared the effect of Aloe vera gel and sweet almond oil on striae gravidarum.

Materials and methods: In this double-blind clinical trial, 160 nulliparous women were enrolled and randomly divided into three case groups and one control group. The four groups were given 700?g Aloe vera, sweet almond oil, and base cream to use topically on the abdominal skin and forth group don’t receive any medication as control group in five steps, they were examined study’s variables (itching, erythema, and spread of striae) using statistical tests in SPSS.

Result: The findings showed that Aloe vera and sweet almond oil creams are more effective than the base cream and the control group to decrease itching and erythema and to prevent the spread of striae on the surface of abdomen (p?p?>?.05).

Conclusions: Aloe vera and sweet almond oil creams reduce the itching of striae and prevent their progression.     

The effect of inhalation aromatherapy with rose essential oil on the anxiety of patients undergoing coronary artery bypass graft surgery

Background and purposeAnxiety is one of the most common responses of patients awaiting coronary artery bypass graft (CABG) surgery to stressful conditions before surgery. This study is intended to examine the effect of inhalation aromatherapy with rose essential oil on the anxiety of patients undergoing CABG surgery.Materials and methodsThis was a single-blind randomized clinical trial of 66 patients undergoing CABG surgery. The experimental group inhaled three drops of 4% rose essential oil for 10 minutes one night and one hour before surgery. The control group did not receive any intervention from the research team.ResultsThe level of anxiety was measured before and 30 minutes after the intervention using the Spielberger's Anxiety Inventory. Prior to surgery, an independent t-test showed that the mean score of anxiety was not significantly different between the experimental and control groups (p = 0.41). Aromatherapy with rose essential oil did not cause any significant differences in state anxiety (P = 0.41), trait anxiety (P = 0.90), and total anxiety (P = 0.69).ConclusionOur results revealed that inhalation aromatherapy with rose essential oil could not significantly reduce anxiety in CABG patients. Future research with larger sample sizes and using different concentrations of rose essential oil are needed to achieve more definitive conclusions.     

The effect of diluted lavender oil inhalation on pain development during vascular access among patients undergoing haemodialysis

ObjectiveThe present study was conducted as a randomised controlled design in order to evaluate the effect of lavender oil inhalation on pain development during vascular access among patients undergoing haemodialysis.MethodsThe study was conducted involving a total of 60 patients receiving treatment at the haemodialysis unit of a public hospital. The data of study were collected using a questionnaire and a Visual Analogue Scale. Lavender oil inhalation containing a 1:10 ratio of lavender and sweet almond oil was prepared.ResultsThe pain mean score of the intervention group was 3.8 ± 0.3 prior to the application of lavender oil inhalation and decreased to 3.0 ± 0.2 following the inhalation application; whereas, the pain mean score of the control group increased from 5.4 ± 0.3 to 5.6 ± 0.6.ConclusionIt was observed that applying lavender oil inhalation to patients undergoing haemodialysis did decrease pain level experienced by patients during vascular access and caused no negative effects.     

Comparing effects of aromatherapy with lavender essential oil and orange essential oil on fatigue of hemodialysis patients: A randomized trial

Background and purposeFatigue is a common complication of hemodialysis. This study aimed to compare the effects of aromatherapy with essential oils of lavender and orange on the fatigue of hemodialysis patients.Materials and methodsNinety subjects were randomly allocated into three groups of aromatherapy with lavender essential oil, aromatherapy with orange essential oil and control. Data collection tool was the Fatigue Severity Scale. In each experimental group, subjects inhaled five drops of lavender essential oil and orange essential oil.ResultsThe difference in the mean of fatigue before and after the intervention in each of the experimental groups was statistically significant, but this difference was not significant in the control group. Between the two groups of aromatherapy, no significant difference was observed in terms of the mean fatigue after the intervention.ConclusionAromatherapy with lavender essential oil and orange essential oil might reduce fatigue in hemodialysis patients.     

三种助孕技术治疗多囊卵巢综合征不孕的疗效比较

目的：观察３种助孕技术：ＩＶＦ ＥＴ、ＧＩＦＴ和控制性超促排卵（ＣＯＨ）后自行同房对多囊卵巢综合征（ＰＣＯＳ）不孕患者的疗效。方法：应用３种方法治疗,观察各组的临床妊娠率和发生卵巢过度刺激综合征（ＯＨＳＳ）的情况。结果：ＩＶＦ ＥＴ和ＧＩＦＴ与ＣＯＨ相比能得到更高的临床妊娠率,而前二者发生ＯＨＳＳ的危险性明显低于后者。结论：为避免ＣＯＨ后发生ＯＨＳＳ,建议对因ＰＣＯＳ不孕的患者采取体外助孕技术治疗。应用何种技术要根据患者的具体情况而定。如果有至少１ 条输卵管完全正常,可先试行ＧＩＦＴ。此外,须将多余的卵子进行体外授精试验,观察其受精及卵裂情况,从而对今后的治疗提出指导性建议,并要将得到的胚胎进行冷冻保存,以备今后使用。     

In vitro study evaluating the instantaneous treatment of ozonised olive oil on human sperm

Objective: The aim of our study was to evaluate the effects of ozonised olive oil (OOO) on human sperm in vitro.

Methods: Human sperm was incubated with OOO for 20?s in vitro. The lowest concentration that completely immobilised all the sperm in 20?s without subsequent recovery of motility was recorded as the minimum effective concentration (MEC). The effects of OOO at MEC on human sperm viability, mitochondrial and acrosomal status, DNA integrity and transmission electron microscopy were observed.

Results: Our findings demonstrate that OOO dose-dependently inhibits sperm motility. The MEC of OOO for 100% sperm immobilisation in 20?s was 6?μg/ml. Further experiments showed that sperm ultrastructure, function and DNA integrity were significantly affected after treatment with 6?μg/ml OOO in vitro.

Conclusions: OOO has spermicidal potential and may be explored as a promising vaginal contraceptive agent.