湿润烧伤膏棉片贴补治疗外伤性鼓膜穿孔

湿润烧伤膏棉片贴补治疗外伤性鼓膜穿孔（附２５例报告）杜友红１外伤性鼓膜穿孔如处理不当，常造成穿孔不愈，并诱发中耳感染，影响听力。既往多采用预防感染，自然愈合法或单纯贴补法。作者１９９３～１９９５年间采用湿润烧伤膏棉片贴补法治疗外伤性鼓膜穿孔２５例２５...     

碱性成纤维细胞生长因子对外伤性鼓膜穿孔的治疗观察

目的 观察碱性成纤维细胞生长因子（bFGF）对外伤性鼓膜穿孔的治疗效果。方法 随机将外伤性鼓膜穿孔分为两组：治疗组66例，用浸湿bFGF的压薄无菌棉片贴补，并每日两次用bFGF喷耳；对照组22例仅用贴补治疗。结果治疗4周后，治疗组鼓膜穿孔愈合率为98.3％，平均愈合时间为10．6天；对照组鼓膜穿孔愈合率为63．6％，平均愈合时间为22.2天。结论 bFGF浸湿棉片贴补加喷耳治疗外伤性鼓膜穿孔可促进穿孔愈合。缩短愈合时间。     

宣纸贴补治疗外伤性鼓膜穿孔(附36例报告)

外伤性鼓膜穿孔后,为促进鼓膜尽快自行修复,1996年至1998年我院采用宣纸涂红霉素眼膏贴补鼓膜治疗外伤性鼓膜穿孔36例.现报告如下.     

凡士林纱条贴补治疗外伤性鼓膜穿孔疗效分析

外伤性鼓膜穿孔常行保守治疗,但多数病例因局部因素或继发感染常会成为永久性鼓膜穿孔,为促进鼓膜穿孔早日愈合,许多学者提出了不同的治疗方法,其效果不一.本科自1999年用凡士林纱条贴补治疗84例（91耳）外伤性鼓膜穿孔取得较好疗效,并同60例（69耳）单纯保守疗法作比较.报告如下.     

贴补法治疗不同程度外伤性鼓膜穿孔疗效观察

目的 探讨贴补法治疗不同程度外伤性鼓膜穿孔的疗效.方法　154例外伤性鼓膜穿孔患者按外伤后贴补治疗时间分为伤后12小时内(A组)、伤后12小时以后(B组),分别行贴补法,观察两组的鼓膜愈合情况.结果 A组大、中、小穿孔愈合率及愈合时间比较差异均无统计学意义(P>0.05);B组大、中、小穿孔愈合率分别为96.43%、72.97%、40.90%,愈合时间分别为10.3±1.2、15.6±2.1、18.1±2.2天,三组比较差异均有统计学意义(P<0.05).结论 外伤性鼓膜穿孔贴补干预的时间愈早,愈合率愈高,时间愈短.     

重组表皮生长因子治疗外伤性鼓膜穿孔的临床观察

目的观察重组人表皮生长因子(reconstruct humar epidermic growth factor,rhEGF)明胶海绵贴补治疗外伤性鼓膜穿孔的疗效。方法rhEGF治疗外伤性鼓膜穿孔68例,按随机分组为治疗组37例,对照组31例。结果rhEGF治疗外伤性鼓膜穿孔,依穿孔部位及形态分为前下、下半、后半和后下4组,治疗组较对照组愈合时间(4周内),分别提前7．5,7．6,12．2,12.6天,未见明显不良反应。结论rhEGF贴补治疗可有效地促进外伤性鼓膜穿孔愈合,缩短愈合时间。     

外伤性鼓膜穿孔棉片贴补后鼓膜生长的动态观察

目的探讨鼓膜穿孔修补术后鼓膜生长愈合的情况。方法对56例(56耳)外伤性中央性鼓膜穿孔患者采取棉片贴补治疗,联合应用耳内镜,每日或隔日更换棉片,对鼓膜生长情况进行动态观察并录像记录,并与43例不用棉片贴补治疗的鼓膜穿孔患者进行比较。结果治疗组鼓膜穿孔愈合率100%,对照组鼓膜穿孔愈合率53.49%(23/43),两组差异有统计学意义(χ2=73.42,P<0.05)。治疗组的鼓膜愈合时间较对照组短。贴补后5天内鼓膜生长较快,中央区愈合慢,边缘区生长快。结论采用棉片贴补治疗外伤性鼓膜穿孔,其贴补物可起"搭桥"作用,促进鼓膜生长。     

明胶海绵贴补治疗外伤性鼓膜穿孔

自1998年以来,用明胶海绵贴补治疗外伤性鼓膜穿孔取得较好疗效,现对112例124耳资料完整并有随访的外伤性鼓膜穿孔病例报告如下.     

0.25%氯霉素浸棉膜片贴补法治疗外伤性鼓膜穿孔

目的　研究 0 .2 5 %氯霉素浸棉膜片贴补法治疗外伤性鼓膜穿孔的疗效。方法　治疗组 4 7例 (5 8耳 )鼓膜穿孔采用 0 .2 5 %氯霉素浸棉膜片贴补修复 ,并于每日早晚用 0 .2 5 %氯霉素滴耳剂滴耳。对照组 4 3例 (5 2耳 )仅用抗生素预防感染。观察并比较两组的鼓膜穿孔愈合情况及听力提高程度。结果　治疗组治愈率 93.6 2 (44 / 4 7) ,语频气导听阈平均提高 2 2 .5± 5 .0dBHL ;对照组治愈率 6 7.4 4 (2 9/ 4 3) ,语频气导听阈平均提高 2 0 .0± 5 .0dBHL ,两组比较 ,有显著性差异 (P <0 .0 1)。结论　 0 .2 5 %氯霉素棉膜片贴补法治疗外伤性鼓膜穿孔效果满意 ,值得推广。     

Sorbalgon贴补治疗外伤性鼓膜穿孔31耳

外伤性鼓膜穿孔是引起听力下降导致中耳炎的原因之一。传统的治疗方法是待其自行愈合，较大的穿孔往往不能自行愈合。2005年11月至今我们采用Sorbalgon藻酸钙伤口敷料行鼓膜复位贴补法治疗外伤性鼓膜穿孔31耳，效果良好，报道如下。     

Tympanic membrane changes in central tympanic membrane perforations

PURPOSE: The objective of this study was to evaluate the histopathological changes in central tympanic membrane perforations caused by chronic otitis media without cholesteatoma. MATERIALS AND METHODS: Twenty-nine temporal bones from 25 patients (13 male patients and 12 female patients) with central tympanic membrane perforations-18 chronic otitis media with perforation and 11 chronic otitis media with perforation caused by ventilation tubes-and 30 aged-matched normal temporal bones were included in this study. A scale was used to evaluate the extension of the migration of stratified squamous epithelium in the inner surface of the tympanic membrane. The thickness of tympanic membranes was measured halfway between the annular ligament and the perforation and compared with that of the normal bones. The presence of tympanosclerosis and papillary projections of squamous epithelium was also noted. RESULTS: The extension of the migration of stratified squamous epithelium in the inner surface of the tympanic membrane was observed in 11 of the 29 perforations (38%). The thickness of tympanic membranes was significantly different between the perforation groups and the control group. Of the 29 tympanic membranes, 13 (44%) had tympanosclerosis and 8 (28%) revealed papillary projections of squamous epithelium. CONCLUSIONS: Our study shows that a central tympanic perforation should not merely be considered as a simple defect. Most of the tympanic membranes showed one or more signs of sequelae or persistent abnormalities such as tympanosclerosis, papillary projections, thickening, and ingrowth without significant differences between the 2 central perforation groups.     

Subglossopalatal membrane

A newborn who experienced respiratory distress just after birth had an oral web that extended from the floor of the mouth anterior to the tongue up to the hard palate. The membrane was slit in the midline to facilitate air exchange. The patient did well without intubation, and the web was resected. To our knowledge, this is the second case of subglossopalatal membrane to be reported. Embryologic and anatomic considerations, along with a review of the literature, are presented.     

Persistent buccopharyngeal membrane

Persistent buccopharyngeal membrane is an extremely rare entity. We report a three-year-old boy who presented with an oral chord-like structure that extended from the base of the tongue up to the posterior part of the vomer. Only seven cases of persistent buccopharyngeal membrane could be found in the review of the literature. Embryology is also discussed.