结节性筋膜炎2例

报告2例结节性筋膜炎.患者均为年轻男性,表现为四肢突然出现的单发皮下结节,组织病理和免疫组化检查结果符合结节性筋膜炎改变.该病较少见,临床表现无明显特征,组织病理形态较复杂,误诊率高,该文结合文献复习了结节性筋膜炎的临床、组织病理学和免疫表型改变,总结了鉴别诊断的要点.     

前臂结节性筋膜炎一例

患者,男,31岁.右前臂皮下结节5天,伴轻度压痛不适.高频超声检查示:表皮连续微隆起,真皮深层及皮下组织可见一类椭圆形低回声结节,边界清楚,体积约6.30 mm×6.23 mm×3.20 mm.皮损组织病理示:真皮及皮下组织大量梭形细胞呈束状排列,胶原纤维增生,间质黏液样变,伴少量淋巴细胞浸润及红细胞渗出.诊断:结节性...     

结节性筋膜炎30例临床病理分析

结节性筋膜炎又称假肉瘤性筋膜炎 ,既非炎症性疾病 ,亦非真性肿瘤 ,而是一种以纤维组织增生为主的软组织瘤样病变。主要累及肢体 ,因生长速度快 ,组织学图像多变 ,核分裂象多见 ,貌似软组织肉瘤 ,极易误诊。现将我们收集的 30例临床病理分析如下。1　临床资料30例患者为 1985年 1月～ 1999年 12月本院及外院会诊病例。年龄 13～ 5 2岁 ,平均 34岁 ,男 18例 ,女 12例。发生于上肢 2 2例 (前臂屈侧 16例 ) ,头颈部和躯干各 4例。 2 0例病变区疼痛、触痛或感觉异常。病程 1～ 2周 2 6例 ,3个月以上 4例。患者无外伤史 ,均因皮下结节手术切除后…     

坏死性筋膜炎1例报告

坏死性筋膜炎１例报告王克威（沪州医学院附属医院皮肤科，６４６０００）朱某某，女，６３岁，因左下肢突然出现大片水肿性红斑、水疱、血疱伴剧烈疼痛于１９９４年８月１５日入院。８月１３日病人感畏寒不适，服感冒冲剂后好转。次日左大腿内侧突然出现大片边界清楚的水...     

坏死性筋膜炎1例

报告1例具有典型症状的坏死性筋膜炎,患者女,70岁,皮损位于左臀部和左大腿,为显著性红斑,硬结、片状坏死,皮损有恶臭,组织中有产气现象,自觉疼痛剧烈,经组织病理检查确诊为坏死性筋膜炎,对患者施行清创术和对症支持治疗,包括消炎,镇痛和补液,获得令人满意的疗效。     

嗜酸性筋膜炎1例

嗜酸性筋膜炎１例候志强（吉林柴油机厂医院皮肤科１３００３１）巫毅，张民夫（白求恩医大二院皮肤科１３００４１）嗜酸性筋膜炎是一种较罕见的疾病，现将我们所诊治１例报告如下：患者女，７８岁，１９９４年１２月２７日入院。２个月前感冒后，腰部出现鲜红色水肿斑块...     

坏死性筋膜炎1例

报告1例坏死性筋膜炎。患者女,57岁。右手背及上肢红肿热痛伴溢脓4d。切开引流见皮下组织及筋膜广泛坏死、液化。皮损组织病理检查示,纤维蛋白样坏死及大量中性粒细胞浸润,脓肿形成。患者乙肝病史多年,住院期间出现大量腹水。经抗生素治疗、局部清创、反复输新鲜血浆和白蛋白,病情稳定,后经植皮痊愈。     

坏死性筋膜炎4例报告

坏死性筋膜炎是由多种细菌混合感染引起的累及筋膜的急性坏死性炎症。现对我院收治的4例该病患者报告如下。     

嗜酸性筋膜炎1例

患者男,22岁。四肢皮肤水肿、硬化1年。查血嗜酸粒细胞340×106/L;ANA1:40(+)。皮损组织病理:真皮血管周围少量淋巴细胞及组织细胞浸润,皮下脂肪可见片状淋巴细胞、较多嗜酸性粒细胞。诊断为嗜酸性筋膜炎。给予强的松、西米替丁、青霉胺口服并联合物理疗法,取得满意效果。     

嗜酸性筋膜炎1例

<正>1病历摘要患者男,49岁。因右前臂红肿及疼痛1个月,于2019年4月15日来克拉玛依市中心医院就诊。患者1个月前锻炼举哑铃后右侧前臂突然出现手掌大的水肿性红斑,轻微疼痛,当地医院拟诊“丹毒”,予青霉素640万U,静脉滴注,每日2次,复方丹参静脉滴注（具体不详）,15d后症状缓解,停药2d后,红肿再次发作,且手     

Cutaneous nodular fasciitis with genetic analysis: a case series

Nodular fasciitis is a benign self‐limited myofibroblastic neoplasm, which usually involves the upper extremities and trunk of young patients. These tumors have been shown to harbor a translocation involving the MYH9 and USP6 genes, leading to overexpression of the latter. We report seven cases of nodular fasciitis with cutaneous presentations. All cases involved the dermis, with six involving the superficial subcutis, and one auricular tumor extending into cartilage. All cases showed USP6 rearrangement by fluorescence in situ hybridization; in two of three cases, the characteristic MYH9‐USP6 fusion was shown by RT‐PCR. All patients underwent conservative resection. Nodular fasciitis is an uncommon mesenchymal neoplasm that can occasionally present in superficial locations and is sometimes mistaken for a malignant process. Molecular testing can be useful to distinguish this entity from other cutaneous spindle cell tumors.     

Intradermal nodular fasciitis of the face

Nodular fasciitis represents reactive myofibroblastic proliferative lesions in the subcutaneous tissue, skeletal muscles, and fascia. Uncommon clinical and pathological variants of nodular fasciitis, such as intravascular, cranial, ossifying, and proliferative fasciitis, have been described. Six cases documenting a dermal location of nodular fasciitis have been reported in the English literature. Some authors have described that the histopathological features of intradermal nodular fasciitis are virtually identical to those of postoperative/posttraumatic spindle cell nodule of the skin. We herein report a 41-year-old Korean woman presenting with a 0.5 cm facial papule in which nodular fasciitis occurred in the dermis.     

嗜酸性筋膜炎一例

患者女,42岁,因四肢关节反复肿痛10余年,四肢皮肤紧绷感、发硬50余天来我科就诊.     

A case of nodular scleroderma

Nodular scleroderma is a rare complication of systemic sclerosis; the pathogenetic implications are still unknown, although many factors are supposed to play a role in lesion development. We report the case of a young woman suffering from systemic sclerosis, who developed nodular lesions during therapeutic management with D-penicillamine and plasmapheresis. In order to better understand the essence of this disease, we examined all the possible pathogenetic mechanisms that could be implicated in nodular lesion development.     

结节性类弹性纤维病1例

<正>临床资料患者,女性,83岁。主因面部皮肤增厚、变黄伴黑头粉刺、囊肿2年,于2010年3月19日来我科就诊。患者于2年前出现面部皮肤增厚、变黄,皮损中出现多个黑头粉刺和皮下小结节、囊肿。皮损处无自觉症状,表面无破溃。既往体健,有失眠、     

结节性硬皮病一例

患者女,39岁.颈部、躯干和四肢起结节,伴手指发冷麻木感10个月.于2001年3月31日来院门诊.     

Dermal nodular fasciitis: three case reports of the head and neck and literature review

Nodular fasciitis is a benign reactive myofibroblastic proliferative process of unknown etiology. It presents as a solitary painless, rapidly growing nodule over several weeks' duration. The condition is self-limited, and proper diagnosis is essential to avoid unnecessary aggressive treatment. Diagnosis is often a challenge because it may be confused with a malignant tumor due to its aggressive clinical behavior and histological features. Immunohistochemical staining can be a useful tool to aid in the diagnosis. Although most commonly located on the extremities and then the trunk, it is estimated that the head and neck region represents only 10 to 20%. The majority of cases arise in the soft tissue, i.e. fascia, muscle, or subcutaneous tissue. Interestingly, cases in the head and neck region often involve dermal tissue. There have been five separate reports documenting rare cases of dermal nodular fasciitis in the dermatopathology literature and one case series involving 28 of 50 dermal variants from the external ear region. We report three additional cases of dermal nodular fasciitis occurring on the left cheek, base of the scalp, and right medial canthus.