Extra digital glomus tumor causing scapulothoracic impingement: A case report

Glomus tumor is a painful benign neoplasm which arises from the glomus body. The glomus body is neuromyoarterial receptor responsible for regulating the peripheral skin blood flow and local temperature. The classical clinical symptoms of the glomus tumor are acute local pain, pin point tenderness and hypersensitivity to cold. The commonest location of the glomus tumor is the subungual region of the distal phalanx of the fingers and toes. We hereby describe a very rare case of extradigital glomus tumor in the interspace between the scapula and the posterior chest wall causing paroxysmal severe pain on the movement of the right shoulder. Being deep in location, the tumor was not clinically palpable or identifiable. The lesion was eventually located on MRI. Surgical resection of the tumor led to complete resolution of patient's symptoms.     

Glomus tumor originating within a digital nerve

Glomus tumors are thought to arise from specialized cells normally found within the glomus apparatus of the dermal stratum reticularis. We report the unusual occurrence of a glomus tumor from within a peripheral nerve. Previous investigators have suggested that the rare occurrence of glomus tumors in tissue where the glomus apparatus has not been described arise from ectopic glomus cells or differentiate from nonglomus cell sources. Many of the "ectopic" glomus tumors have been found in regions of extensive arteriovenous shunting such as in the digestive system and lung suggesting the presence of glomera at these locations. The finding of a glomus tumor within a peripheral nerve, a region where extensive arteriovenous shunting and glomus bodies have not been described, supports the occasional origin of a glomus tumor from a nonglomus cell source.     

Subungual glomus tumors of the fingers: ultrasound diagnosis

INTRODUCTION: Glomus tumors of the fingers are rare, benign tumors. These lesions are hamartomas, originating from dermoepidermic glomus, most commonly located at the distal phalanx, and in particular under the nail. Diagnosis is often delayed because of the absence of specific symptoms. Confirmation can only be made by histological study. The aim of this retrospective study is to define the role of ultrasound examination in the diagnosis of glomus tumors of the fingers. METHOD: During the period March 2002-March 2004, 12 cases of subungueal glomus tumors were included in this retrospective study. All patients underwent ultrasound and Doppler examinations before surgery. All Ultrasound Doppler studies were performed by the same radiologist. The mean age of patients was 44 year-old and the sex-ratio was 1/2. RESULTS: Pain was noted as a symptom in all patients. The mean size of the tumor was 3.5 mm. In eleven patients, ultrasound study was able to confirm the diagnosis, but it failed in one case because of the small size of the tumor (less than 2 mm). Ten tumors presented a Doppler hypersignal, located in the tumor and compatible with the diagnosis of glomus tumor. DISCUSSION: Diagnosis of glomus tumor is based on clinical examination, standard radiology, and ultrasound Doppler study. Ultrasound examination and Doppler study gives better visualization of tumors compared to standard radiology. These studies are useful for follow-up of patients in the post-operative period.     

Tumeur glomique extradigitale : une cause rare de douleur chronique de cheville

Glomus tumors are rare benign tumors. The most frequent localization is the hand, particularly, the fingers. An atypical anatomical localization remains rare. It can make the diagnosis difficult and delayed, which alters the quality of life of the patients. The diagnosis is confirmed by histological examination. We report a very rare localization of glomus tumor in the ankle region and we discuss the epidemiological, diagnostic, and therapeutic aspects of these tumors.     

Glomus tumor of the mesocolon

Glomus tumors are rare distinctive benign neoplasms, which arise from modified smooth muscle cells of the normal glomus body and are most commonly located in the subungual region of the finger. Intraabdominal locations are relatively rare. We report a case of glomus tumor of the mesocolon in a 10-year-old girl. Surgical exploration showed a lesion in the transverse mesocolon, which was excised. Histopathology showed it to be a glomus tumor of the mesocolon.     

Glomus tumor of the penis

Glomus tumors of the penis are extremely rare. A patient with multiple regional glomus tumors involving the penis is reported. A 16-year-old boy presented with the complaint of painless penile masses and resection of the lesions was performed. The pathologic diagnosis was glomus tumor of the penis. This is the ninth case of glomus tumor of the penis to be reported in the literature.     

Glomus Tumor in a Segmental Bronchus: A Case Report

Glomus tumors originate from a neuroarterial structure called the glomus body, and grow mostly in soft tissue. It is rare for glomus tumors to develop in the respiratory system. The patient of the present case had an abnormal shadow in the right lung on chest X-ray, and computed tomography (CT) findings displayed a lung tumor in the right S6. Bronchoscopy was performed for the diagnosis of the lung tumor, and a polypoid bronchial tumor was unexpectedly found to occupy the right B3. The bronchial tumor was diagnosed as a glomus tumor, and the lung tumor was diagnosed as an adenocarcinoma. The bronchial glomus tumor was cauterized by argon plasma coagulation (APC). Three weeks after the cauterization by APC, the right lower lobectomy was performed for the treatment of the lung adenocarcinoma. The patient has remained disease free for 2 years.     

Glomus tumor and glomangioma of the nerve. Report of two cases

As a rule, normal human nerve does not contain glomus bodies. Nonetheless, rare examples of glomus tumors do arise in peripheral nerves of various sizes. Their pathobiological characteristics are poorly understood, but reported examples have been small and clinically benign. The authors identified in 1 patient each a glomus tumor and a glomangioma involving nerve. Clinical histories as well as imaging and surgical findings were reviewed. All available H & E-stained slides were examined in both cases. Immunohistochemical stains and electron microscopy, as appropriate, were also performed. The lesions were subtotally and completely resected, respectively. An uneventful postoperative recovery was noted in both patients. Glomus tumors and glomangiomas can involve major nerves on rare occasions. They seem to follow a favorable clinical course, and conservative resection can be of benefit.     

Renal glomus tumor in an adolescent: a conservative approach

The most common renal neoplasms in the second decade of life are renal cell carcinomas and Wilms' tumors. Glomus tumors arising in the kidney are rare. We report an adolescent with a benign renal glomus tumor excised by wedge resection. Nephron-sparing surgery is the therapy of choice for children with benign renal tumors. Glomus tumor should be considered in the differential diagnosis of a renal mass in a young patient.     

Pediatric glomus tumors

Glomus tumors of the middle ear are unusual in adults, but exceedingly rare in children. While a dull, red bulging tympanic membrane in the adult may suggest a glomus tumor, it generally signifies infection in the child. This report details our management of a 10-year-old girl afflicted with bilateral chronic middle ear cleft infection that obscured bilateral glomus tumors. Review of the current English language literature reveals seven additional case reports of otologic glomus tumors in children less than fourteen years of age. Two additional cases are presented that were given to the senior author by personal communication, producing a total of 10 cases for review. Glomus tumors in children may be hidden by otitis media and appear more likely to be endocrine active. Failure to cure the lesion is apparent in five of six case reports of children with glomus jugulare tumors; three of these children are reported to have expired. Complete surgical extirpation is advocated for childhood glomus tumors.     

Glomus tumor of the glans penis

Glomus tumors of the penis are extremely rare. We report a patient with a solitary glomus tumor involving the penis. A 19-year-old man presented with a complaint of a recurrent painful penile mass. Resection of the lesion was performed. The pathologic diagnosis was glomus tumor of the glans penis. This case emphasizes the need for complete extirpation of the glomus tumor to avoid additional surgery.     

Glomus Tumor in the Tarsal Tunnel: A Case Report

Glomus tumors are painful benign neoplasms. They commonly present in the hand and are mostly solitary lesions. We report a rare case of multiple glomus tumors in the lower leg. Moreover, 1 of the tumors was in the tarsal tunnel. Resection of the tumors resulted in the early diagnosis of glomus tumors and complete symptom relief. Because of its rarity, diagnosing an extradigital glomus tumor is difficult. Recognition of glomus tumors allows for an early diagnosis and resection, and preoperative magnetic resonance imaging helps in the detection of multiple lesions. Before resection, we considered tarsal tunnel syndrome in the differential diagnosis because of the symptoms and location of the tumor. Tarsal tunnel syndrome is a comparatively well-known disease in the foot. When tarsal tunnel syndrome is suspected, a glomus tumor should also be considered in the differential diagnosis.     

Tracheobronchial glomus tumor

Glomus tumors are uncommon. A review of the literature for tracheobronchial glomus tumors revealed 13 tracheal glomus tumors. The diagnosis may be elusive and so the true incidence of tracheobronchial glomus tumors may be greater than that reported. Three of the 14 glomus tumors were initially believed to be carcinoid. Glomus tumors should be included in the differential diagnosis of tracheobronchial tumors.     

手指血管球瘤26例临床分析

目的　探讨手指血管球瘤的诊断和手术方法。方法　 1996年 1月 -2 0 0 2年 12月 ,对 2 6例手指血管球瘤进行诊治。术前 2 6例Love氏试验阳性 ,冷敏感试验阳性 ,2 0例Hildreth氏试验阳性 ,15例中 11例透光试验阳性 ,1例X线侧位片显示末节指骨有肿瘤压迹。全部病例均采取肿瘤切除手术。结果　术后随访 11个月～ 7年 9个月 ,无 1例肿瘤复发。 2 6例疼痛完全消失 ,术前阳性症状全部消失。 2 2例指甲生长良好 ,无明显畸形。结论　提高对血管球瘤的认识 ,有助于早期诊断 ,早期治疗 ,完整切除肿瘤是提高临床疗效的关键。     

Glomus Tumor of the Great Toe

Glomus tumor is a rare mesenchymal neoplasm composed of cells that resemble the modified perivascular smooth muscle cells (glomus cells) of the normal glomus body. A glomus tumor can appear in any part of the body, although it mostly appears in the extremities, especially in the subungual area of the hand. It has been less commonly reported in the foot. A case of glomus tumor of the pulp of the hallux is described in the present report.     

Primäres Glomangiom der Leber Eine neue Differenzialdiagnose benigner Lebertumoren

Glomus organs are arteriovenous anastomoses which control the thermoregulation of the extremities. Benign tumors of these glomus organs, termed "glomangiomas", are therefore most frequently located in the fingers and toes. Case reports of primary glomangiomas in the respiratory- and gastrointestinal tracts as well as in the genital organs have been published. On the other hand, glomus tumors of the liver have not yet been described. We report the case of a 61-year-old patient with a smooth subcapsular lesion within the liver detected by a routine ultrasound scan. Further diagnostic imaging did not match with one of the common liver tumors. The diagnosis of a glomangioma was finally made by liver biopsy and subsequent histology. A review of the literature revealed a potential transformation of glomangiomas. Since the patient reported on inappetence weight loss and the tumor showed growth tendency, the indication for surgical excision was made. Final histologic investigation revealed no signs of malignancy. The primary glomangioma of the liver is a new differential diagnosis of benign liver tumors. As there is a possibility of malignant degeneration, we propose the decision for surgical removal once there are clinical symptoms and a growth tendency of the lesion.     

Primary glomangiosarcoma of the lung: A case report

Background  

Glomus tumor is an uncommon neoplasm derived from cells of the neuromyoarterial glomus or glomus body. Most glomus tumours occur in the dermis and subcutaneous tissues. A case of a primary pulmonary glomus tumour originating in the right upper lobe is presented.     

Subungual glomus tumors of the hand: Treated by transungual excision

Background:Glomus tumors are benign hamartomas arising from the glomus body, mostly occurring in the subungual region of the digits. A triad of excruciating pain, localized tenderness and cold sensitivity is the key to diagnosing these tumors. Two surgical approaches are described in the literature for excision of subungual glomus tumors-transungual and periungual. We reviewed retrospectively the results of subungual glomus tumors of the hand treated by transungual excision.Results:All patients had complete pain relief. There was no new nail deformity and no recurrence till last followup. One patient had deformity of the nail preoperatively due to previous surgery, which persisted after excision of the tumor. All of them returned to their preoperative occupation and regained full function of the hand.Conclusions:The transungual approach provides good access to the entire lesion and facilitates complete excision. Contrary to reported literature, we did not find the development of any new nail deformity with this approach.     

Glomus tumors: report on eleven cases and a review of the literature

INTRODUCTION: Glomus tumor is a well known pathology in hand surgery; in addition to sites in the upper limbs, it can also affect the lower limbs and develop in other parts of the body. MATERIALS AND METHODS: Seven females and four males with glomus tumors underwent surgery between 1990 and 1998 at our hospital. These cases were retrospectively studied, and immunohistochemical staining was carried out for vimentin, factor VIII and CD34. RESULTS: At the time of diagnosis, the mean age of the patients was 49 years, with a mean follow-up of 18.5 months. Regarding tumor site, there were six digital, one wrist, two neck and two lower limb locations. In this series, familial incidence was observed in two cases, i.e., two sisters with tumor occurrence at the same digital site. Tumor size varied from 0.2 to 5 cm. In agreement with the findings in the literature, the present results showed only a low incidence of locations other than in the upper and lower limbs. Moreover, no multiple locations or degenerative malignancy were observed, both of which are known to be rare. In all cases, the histological aspect of these tumors was typically benign. Immunohistochemical studies of the tumor cells were positive for anti-vimentin antibody in all cases, negative for anti-factor VIII in all cases and irregularly positive for anti-CD34 antibody. DISCUSSION: It was not possible to confirm the specificity of the anti-CD34 antibody for glomus tumor in this series. The hypothesis of the endothelial origin of glomus tumor can probably be dismissed in the absence of the expression of anti-factor VIII and anti-CD34 antibodies.     

Glomus tumor of digital nerve: case report

Glomus tumors consist of modified perivascular, smooth muscle involved in thermoregulatory activity of digital blood flow. Digits, especially in the subungual region, are often affected. These tumors only rarely arise in peripheral nerves; digital nerve involvement is exceptional. We describe a glomus tumor occurring in the digital nerve at the level of the distal phalanx.