The cloning controversy

Stem cell research has captured the imagination of many, including the scientific and medical community. But the medical community received a wake-up call early this year when a well-known researcher publicly confessed to deception. While the core question relates to honesty and integrity, it is equally necessary to examine the system that made such deception possible.     

The tonsil and adenoid controversy

This paper will review the anatomy, histology, immunology, bacteriology, indications, complications, and trends in modern tonsil and adenoid surgery. Information on tonsils and adenoids, both in their normal and abnormal states, has proliferated over the last two decades. A considerable variation in opinion remains on the subject. Historical fluctuations in the indications for tonsil and adenoid surgery have resulted in swings in the quantity of surgery performed. This paper will attempt to bring contemporary information together to provide reasonable guidelines for management of disease tonsils and adenoids.     

干细胞与肿瘤干细胞

目的了解干细胞、肿瘤干细胞和恶性肿瘤关系的研究进展。方法复习国内外相关文献,综述肿瘤干细胞与干细胞的关系、肿瘤干细胞与恶性肿瘤发生发展的关系、研究现状、前景及存在的问题。结果正常干细胞和肿瘤干细胞之间存在很强的相似性,其中淋巴造血系统恶性肿瘤和少数实体瘤干细胞分离鉴定的成功有力支持了肿瘤干细胞理论。结论肿瘤干细胞理论可解释很多恶性肿瘤的生物学行为,但目前仍迫切需要相关分离、纯化、鉴定实体瘤干细胞的思路和方法。     

造血干细胞移植应用研究

造血干细胞移植（hematopoietic stem celltransplantation,HSCT）是近30年来开始发展并逐渐完善与推广应用的治疗一些疑难重症的有效疗法。其治疗策略是采用超大剂量化疗和全身放疗,达到清除肿瘤细胞或异常细胞的目的,然后将正常人的造血干细胞植入患者的体内,使患者得以重建,恢复正常的造血功能,达到治愈疾病的目的。HSCT治疗成功,明显提高了恶性肿瘤、白血病、再生障碍性贫血和一些疑难重症的远期疗效,也使一些严重的、临床缺乏有效药物治疗的遗传性血液病和先天性免疫缺陷病得到根治。