银涟露中游离氨基酸及微量元素的含量测定

对银涟露中游离氨基酸、微量元素含量进行了研究，结果表明本品不仅含有人体必需氨基酸而且含有对人体有益的必需微量元素。重金属铅、砷、镉未检出，铜未超出有关规定。     

20种甘肃地产药材中铅、砷、镉、铜的含量测定

目的 对甘肃20种地产药材进行铅、砷、镉、铜的含量测定.方法 采用石墨炉原子吸收分光光度法对铅、镉进行测定,火焰原子吸收光谱法对铜进行测定,氢化物发生原子吸收分光光度法对砷进行测定.结果 20种药材中不同程度地检出重金属铅、砷、镉、铜元素,除刺五加中镉含量超标外,其余药材中重金属铅、砷、镉、铜含量低于限定值.结论 加强对中药材重金属含量的监测和管理十分必要.     

牛耳枫等五种药材重金属元素含量分析

目的 测定牛耳枫、三叉苦、胆木、青牛胆、山苦茶五种药材中重金属元素含量.方法 采用石墨炉原子吸收光谱法测定五种药材中铜、铝镉含量,用氢化物原子荧光法测定其中的砷、汞含量.结果 牛耳枫中5种重金属元素(铜、镉、铅、汞及砷)含量分别为6.700,0.080,3.000,0.052,0.690mg/kg;三叉苦中5种重金属元素(铜、镉、铅、汞及砷)含量分别为4.300,0.040,1.600,0.040,0.820mg/kg;胆木中5种重金属元素(铜、镉、铅、汞及砷)含量分别为2.700,0.020,1.250,0.038,0.400mg/kg;青牛胆中5种重金属元素(铜、镉、铅、汞及砷)含量分别为5.000,0.120,0.690,0.050,0.620mg/kg;山苦茶中5种重金属元素(铜、镉、铅、汞及砷)含量分别为4.400,0.075,0.520,0.044,0.480mg/kg.结论 5种药材重金属含量均符合药用植物及制剂的外经贸绿色行业标准.     

广西德保和凤山黑糯米中微量元素的测定

采用原子吸收分光光度法测定广西德保产及凤山产黑糯米中的Ｚｎ、Ｃｕ、Ｍｎ、Ｆｅ、Ｃｏ、Ｎｉ、Ｃｄ、Ｐｂ、Ｃｒ、Ｎａ、Ｋ、Ｒｂ、Ｌｉ、Ｓｒ、Ｃａ、Ｍｇ、Ｓｅ、Ｓｅ等１８种微量元素，发现其中的锌、锰、铁、钠、钾、铯、钙、镁等微量元素含量均较高，两地产黑糯米中的锰、铁、钾、钙、镁的含量差异无显著性（Ｐ＞０．０５），锌和锂的含量差异有显著性（Ｐ＜０．０５），铜、钴、镍、镉、铅、铬、钠、铯、锶、钼、硒的含量差异有高度显著性（Ｐ＜０．０１）。此结果表明：黑糯米中含有丰富的人体必需微量元素，提示德保、凤山两地产黑糯米作为天然营养补充物质，具有极高的营养价值。     

广西产土垅大白蚁菌圃中几种重金属的含量测定

目的:探查广西产土垅大白蚁菌圃中铅、镉、砷和汞等重金属的含量.方法:采用原子吸收分光光度法对12批土垅大白蚁菌圃进行铅、镉、砷和汞等元素的测定,其中铅测定采用火焰法,镉采用石墨炉法,砷和汞采用氢化物原子荧光法.结果:铅在0～1.00 mg/L、镉在0～5.0 μg/L、砷在0～64.0 μg/L、汞在0～16.0 μg/L范围内线性关系良好, 12批样品铅含量为6.0～19.1 mg/kg, 镉为0.11～0.40 mg/kg,砷为0.14～0.82 mg/kg,汞为0.050～0.520 mg/kg.结论:广西不同产地的土垅大白蚁菌圃上述重金属含量较低,临床使用具有一定安全性.     

制首乌饮片中的砷及重金属元素含量研究

目的提供市售不同产地中药饮片制首乌中的砷及重金属元素的含量水平，为中药标准的制定提供可行性建议。方法采用石墨炉原子吸收光谱法测定市售不同产地制首乌中的铜、铅、镉含量，用氢化物原子荧光法测定其中的砷、汞含量。结果收集的四种市售制首乌饮片样本中仅有一种饮片的铜、铅、镉、砷、汞五种元素含量符合要求，而大多数样本的铅、砷、汞含量超标，有的严重超标。结论不同产地制首乌饮片中铅、砷、汞含量差异较大，在应用时须加以注意。     

曲札茋苷原料中铅、镉、铜、砷、汞残留量的测定

目的建立曲札茋苷原料中铅、镉、砷、汞、铜检测方法,测定不同批次中铅、镉、砷、汞、铜残留量。方法采用微波消解样品,以石墨炉原子吸收分光光谱法测铅、镉含量,以火焰原子吸收分光光度法测铜含量,以氢化物发生-原子荧光光谱法测砷、汞含量,并对方法进行方法学考察。结果铅、镉、铜、砷、汞的回收率（n=9）分别为95.18%、96.29%、101.32%、97.88%、86.76%. 结论本法简单、快速、准确,可用于原料中铅、镉、铜、砷、汞残留量的测定。     

保定市母乳中微量元素及有毒元素含量的研究

目的 了解保定市区产妇的乳汁中3种微量元素锌、铜、锰和4种有毒元素(铅、砷、镉、汞)的含量,从而间接评估该地区婴儿6个月纯母乳喂养期间从母体获得微量元素和有毒元素的情况,从而提出针对性的措施.方法 采用随机抽样的方法选择保定市区健康第1胎足月产妇206例,采集母亲乳汁10mL,用等离子体质谱仪测母乳中3种微量元素及各种重金属元素.结果 与国际原子能机构的标准及国内的一些地区调查结果比较,保定地区母乳中锌、铜、锰3种微量元素的平均含量处在较高水平;铅、砷、镉、汞的污染程度也相对较高.结论 保定市区产妇母乳中3种微量元素平均含量充足;而母乳中重金属元素的污染通过乳汁对婴儿造成的危害也应该引起足够的重视.     

枳壳中重金属及砷的含量测定

目的：测定枳壳主产区枳壳药材中铅、镉、汞和砷的含量。方法：Pb、Cd用石墨炉原子吸收分光光度法(AAS)测定；Hg、As用原子荧光法(AFS)测定。结果与结论：枳壳中未检出Pb和Cd，而且As和Hg的含量均较低，建议枳壳药材中铅、镉、汞和砷可免检。     

烟草中无机元素及氨基酸分析

用原子吸收法分析云南烟草中１１种无机元素的含量；用氨基酸分析仪测定烟草中１７种氨基酸的含量．结果表明：不同样品中Ｍｇ，Ｋ，Ｆｅ等的含量差异较大，除Ｋ，Ｚｎ，Ｌｉ外，其它８种无机元素都是烟末含量最高，人体必需的微量元素如Ｃｕ，Ｚｎ，Ｍｎ，Ｆｅ等都有较高的含量；不同样品中氨基酸总量相差２～３倍，烟末中所含１７种氨基酸量均高于烟叶和烟梗中的含量，烟末中氨基酸总量达６９６４９ｍｇ／ｇ，具有较高的应用价值．     

罕见小肠囊腺瘤1例报道

SUMMARY In recent years, there have been more and more reports about cystadenoma. Cystadenoma can occur in many parts of the body, and cystadenoma in different parts may show different clinical symptoms, however, some patients with cystadenoma have no symptoms. The vast majority of cystadenomas are benign lesions, but a small number of cystadenomas can be malignant. For example, a small number of ovarian cystadenomas and pancreatic cystadenomas may be malignant. This study reported a patient with small intestinal cystadenoma diagnosed by pathology. The patient's physical examination revealed a lesion in the left upper abdomen. He had only abdominal distension and no other discomfort. His laboratory examination results were basically normal, i.e. blood routine, urine routine, stool routine, liver function, kidney function, myocardial enzyme, tumor marker, etc. The patient underwent sectional small intestine resection and the pathological sample was analyzed. The histological findings of the resected intestinal sample were consistent with cystadenoma. Computed tomography scan of the abdomen was performed 4 months after the surgery. No recurrence of the tumor was found. The patient recovered in good condition. By consulting the literature, I found very few reports of small intestinal cystadenoma before, it was very rare. This article described the clinical manifestation, diagnosis and differential diagnosis, treatment and prognosis of a case of small intestinal cystadenoma, it suggested that cystadenoma can occur in the small intestine, other than the ovary, pancreas, liver, lung, thyroid, prostate, seminal vesicle, skin, etc. The cystadenoma in small intestine is easy to be mistaken with other tumors, such as small intestine stromal tumor, small intestine adenocarcinoma, small intestine lipoma, small intestine hemangiomas, etc., and it is difficult to fully confirm through imaging examinations, such as computed tomography and magnetic resonance imaging. Laparotomy and histopathological examination are necessary before definitive diagnosis. This disease can be treated by small bowel resection at the affected region and good prognosis can be achieved.     

H-FABP在急性冠状动脉综合征早期诊断及预后评估中的价值

[摘要] 目的 探讨心脏型脂肪酸结合蛋白( heart-typefattyacidbindingprotein , H-FABP )在急性冠状动脉综 合征( acutecoronarysyndrome , ACS )早期诊断及预后评估中的价值。方法 采用前瞻性研究对 173 例胸痛发作 12 h 内的患者分别检测 H-FABP 、肌钙蛋白 I ( troponinI , cTnI )及肌红蛋白( myoglobin , MYO )、肌酸激酶( creatine kinase , CK )、肌酸激酶同工酶( creatinekinase-MB , CK-MB )等生化指标,并观察患者住院期间主要不良心脏事件 ( majoradversecardiacevents , MACE )发生情况,收集、统计并分析相关资料。结果 在胸痛发作 0~3h , H-FABP 在急性心肌梗死( acutemyocardialinfarction , AMI )组的阳性率高于 cTnI 、 MYO 、 CK 、 CK-MB ,其差异有统计学意 义( P <0.05 ); H-FABP 的敏感度、阳性预测值、准确度及 Youden 指数均高于 cTnI 、 MYO 、 CK 、 CK-MB 。 在胸痛 发作 >3~6h , H-FABP 在 AMI 组的阳性率与 cTnI 和 MYO 相似( P >0.05 ),但高于 CK 、 CK-MB ( P <0.05 ); H- FABP 的敏感度、阳性预测值、准确度及 Youden 指数与 cTnI 相似,但高于 MYO 、 CK 、 CK-MB 。 在胸痛发作 >6~12h , H-FABP 的阳性率、敏感度与 cTnI 相似( P >0.05 ),其阳性预测值、准确度及 Youden 指数与 cTnI 、 CK 、 CK-MB 相 似,但高于 MYO 。 在 0~12h 内, H-FABP 的特异度与 cTnI 相似,但高于 MYO 、 CK 、 CK-MB 。 H-FABP 在胸 痛发作 3h 内的诊断价值远远高于其他指标。 H-FABP 、 H-FABP+cTnI 的阴性预测值高于 cTnI 、 MYO 、 CK 、 CK-MB 。 AMI 组住院 1 周内 MACE 发生情况, H-FABP 的 OR 值为 2.761 , 95% CI 为 0. 704~0.902 。结论 H- FABP 可作为早期诊断 AMI 的敏感指标,尤其在 3h 内显著优于其他指标。 cTnI 联合 H-FABP 在 6h 内显著提高 cTnI 的阴性预测值,可用于胸痛早期 AMI 排除诊断。 H-FABP 是 AMI 的 MACE 发生的危险因素。     

温度对三种蚊虫发育和繁殖的影响

目的 观察白纹伊蚊、淡色库蚊和中华按蚊等3种江苏省主要传病媒介在不同温度条件下各虫期发育与繁殖情况,了解蚊虫完成全代发育的有效温度,为制定或实时调整蚊虫防制措施提供理论依据。方法 2017年用光照培养箱饲养法,设置10、15、20、25、30、35和40 ℃等7组不同温度,分别观察实验室饲养的白纹伊蚊、淡色库蚊和中华按蚊生殖营养周期、卵期、幼虫和蛹期的发育繁殖和全发育时期情况。结果 在7组温度中,白纹伊蚊和中华按蚊在10、15和40 ℃时不能完成蚊虫全代发育,其余4组温度均能完成全代发育,其中在20、25、30和35 ℃时白纹伊蚊的平均发育时间分别为37.73、18.50、16.92和13.66 d,中华按蚊的平均发育时间分别为29.13、15.46、12.19和10.90 d;淡色库蚊除40 ℃不能完成全代发育外,其余6组温度均能完成全代发育,按照温度递增顺序平均时间分别为80.88、46.32、31.07、24.97、17.14和14.48 d。结论 一定温度范围内,蚊虫的发育周期随着温度升高而缩短,温度过高和过低均对蚊虫发育繁殖起到损害作用;温度对3种蚊虫的发育与繁殖影响有所区别。     

Chemical and Pharmacological Researches on Hyoscyamus niger

The reports on chemical constituents of Hyoscyamus niger were summarized. The compounds include alkaloids, saponins, lignans, coumarinolignans, flavonoids, and some other nonalkaloidal compounds. TLC, HPLC, and GC were used for the qualitative and quantitative analyses of some chemical constituents in H. niger. Modern pharmacological experiments showed that H. niger had the analgesic, anti-inflammatory, antipyretic, anticonvulsant, spasmolytic, antidiarrhoeal, antisecretory, bronchodilatory, urinary bladder relaxant, hypotensive, cardiosuppressant, vasodilator, antitumor, and feeding deterrent properties. In addition, the toxicities of this medicinal plant were also described.     

New Spectacle on Dementia——Concern together brain healthy of humanity

Dementia is a syndrome due to brain disease and is characterized by a progressive, global deterioration in intellectual abilities, including memory, learning, orientation, language, comprehension, and judgment. Alzheimer＇s disease, in particular, is progressive and fatal. It mainly affects older people, especially those o- ver aged 65. From this age, dementia prevalence doubles every five years. Dementia is one of the major causes of disability in late - life. Alzheimer＇ s disease is the most common cause of dementia, vascular dementia, dementia with Lewy bodies, and frontotemporal dementia are the next most common.     

藜草花粉变应原免疫活性分析

目的:分析藜草花粉变应原成分及其变应原性、免疫原性.方法:用Sephacryl S-200HR葡聚糖凝胶层析法分离、纯化藜草花粉变应原,通过十二烷硫酸钠-聚丙烯酰胺凝胶电脉法(SDS-PAGE)测定变应原各组分的分子质量;应用免疫印迹法检测各组分蛋白质与藜草花粉过敏性哮喘患者血清中sIgG和sIgE的反应率.结果:藜草花粉经电泳后得到12条蛋白质区带,分子质量依次为92,63.1,61,52,45,43,39.7,38.9,34,31.6,28.4和18.5～12 ku;免疫印迹可见4条sIgE反应带,蛋白分子质量依次为92,34,31.6和18.5～12 ku;与患者血清反应率分别是70%,50%,80%和90%;与血清sIgG结合的反应带有8条,蛋白分子质量为92,61,52,45,43,39.7,31.6和18.5～12 ku;与患者血清反应率分别是80%,40%,10%,20%,80%,10%,10%和100%.结论:藜草花粉变应原主要含12种蛋白质成分,其中分子质量为18.5～12 ku和92 ku的蛋白质变应原活性及免疫原活性均很强,是主要变应原成分;分子质量在34和31.6 ku的蛋白质有较强的变应原性而无或仅有较弱的免疫原性;而分子质量为43,61,45,52和39.7 ku的蛋白质具有一定的免疫原性而无变应原性.     

脑室分流术在感染后脑积水患儿中的应用

目的：探讨脑室分流术在感染后脑积水患儿中的应用价值。方法：选取行脑室分流术的脑膜炎后脑积水 患儿24例。对患儿的临床资料进行回顾性分析，包括性别、起病年龄、病程、临床表现、实验室检查结果、治疗经 过、手术方式、并发症及后遗症等。结果：24例患儿，痊愈8例，遗留轻微后遗症11例，严重后遗症2例，植物状态1 例，死亡2例(细菌性脑膜炎1例、结核性脑膜炎1例)，后遗症以癫痫、智力损害、视听损害为主。结论：脑室分流术 对脑膜炎后脑积水患儿有确切的临床疗效，有助于改善患者远期预后，是治疗感染后脑积水的重要方法。     

EFFECTS OF SDS, PBS SOLUTIONS UPON FLUORESCENCE VALUES OF DERMATOPHA GOIDES PTERRONYSSINUS RADIOALLERGOSORBENT TEST INHIBITION

Objective To explore the effects of SDS, PBS re-dissolvent solutions on fluorescence values of radioallergosorbent test (RAST) inhibition. Methods Dermatophagoides pterronyssinus allergen immunoCAP and UniCAP 100 System were used. The Sera Pool consisted of 20 Dermatophagoides pterronyssinus allergic patients sera, their specific IgE fluorescence values were between 12 505 and 24 776. Results Fluorescence value percentages decreased: 62.9%, 54.1%, 43.5%, 6.7%, 3.7%, 2.6%, 2.2%, and 1.4% respectively, when SDS concentrations were at 2%, 1%, 0.5%, 0.25%, 0.1%, 0.05%, 0.025%, and 0.01%. Fluorescence values decreased more than 5% with SDS concentrations equal to 0.25% or higher. PBS in 0. l and 0.01 mol/L concentrations decreased fluorescence values 2.9% and 0.9% respectively. Conclusions SDS is a commonly used surfactants in allergen extract and re-dissolvent prepared allergen precipitation for RAST inhibition. Thus effects of surfactants (e.g. SDS) upon the RAST inhibition tests must be considered when they were used as re-dissolvent agents to improve protein resolution in RAST inhibition.     

Clinical analysis of neurological system complications in AIDS and HIV positive patients

Objective：To report the clinical manifestations of AIDS with nervous system complications. Methods：We collected the clinical material of AIDS and HIV positive patients who were admitted to our hospital from January 1998 to July 2006, and retrospectively analyzed the 39 cases having nervous system complications, among 146 cases in total. Results：Among 39 cases, there were 3 cases of HIV dementia, 1 case of vacuolar myelopathy, 3 cases of Gullain-barre syndrome, 3 cases of myopathy and 26 cases of secondary opportunistic infection of CNS,including 9 cases of tuberculosis, 6 cases of cryptococcus, 5 cases of toxoplasma, 3 cases of herpes zoster virus, 2 cases of herpes simples virus, 1 case of cytomegalovirus, 1 case of progressive multifocal leukoencencephalitis. 2 cases with central nervous system lymphoma.Among them 12 patients gave up treatment, other patients received anti-HIV treatment and antimicroorganism treatment. 5 patients died of respiratory failure, 2 patients died of multiple organs failure. Conclusion：Up to now, AIDS still has not very good management. So prevention is very important.     

子宫内膜癌495例的组织分型和预后分析

本文对495例子宫内膜癌进行了形态特点、组织起源及生物学行为的分析。病例在组织学上可分为内膜样腺癌、腺角化癌、透亮细胞癌、分泌型腺癌、鳞腺癌、浆液乳头状腺癌和粘液型腺癌等七型。根据肿瘤组织形态及生长部位,认为他们均起源于子宫内膜具有多种分化潜能的苗勒管上皮。经统计学处理,发现各型的临床分期、肌层浸润情况和肿瘤分化程度有所不同;生存率也有显著差异(p<0.01),说明组织分型是一项估计预后的病理形态指标。