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Ji-Sung Park MD Young-Mi Park MD Eun-Kyung Kim MD Suk-Jung Kim MD Sang-Suk Han MD Sun-Joo Lee MD Hyun-Sin In MD Ji-Hwa Ryu MD 《Journal of ultrasound in medicine》2010,29(12):1687-1697
Objective. The purpose of this study was to differentiate between high‐grade and non–high‐grade ductal carcinoma in situ (DCIS) of the breast on sonography. Methods. From October 2003 to August 2009, 76 DCIS lesions in 73 women who underwent sonography and mammography were included in this study. Lesions were confirmed by mastectomy, breast‐conserving surgery, or surgical biopsy. Images were analyzed by 2 radiologists with consensus and were correlated with histologic grades. Results. Of the 76 lesions, 44 were classified as high‐‐grade and 32 as non–high‐grade DCIS. Fifty‐seven lesions (75.0%) were identified on sonography, which revealed a mass in 30 cases, microcalcifications in 20, ductal changes in 4, and architectural distortion in 3. All cases with false‐negative findings on sonography (n = 19) showed microcalcifications on mammography. On sonography, masses were more frequently found in non–high‐grade (62.5%) than high‐grade DCIS (22.7%; P < .01). No significant difference was seen in the sonographic features of masses between high‐grade and non–high‐grade DCIS. Microcalcifications were more common in high‐grade (43.2%) than non–high‐grade (3.1%) DCIS (P = .02). Most sonographically visible microcalcifications had associated findings such as ductal changes (n = 11), a mass (n = 7), or a hypoechoic area (n = 5). The detection rate of microcalcifications on sonography was higher in high‐grade (62.9%) than non–high‐grade DCIS (25.0%; P = .023). Conclusions. Microcalcifications with associated ductal changes (11 of 31 [35.5%]) were the most common sonographic findings in high‐grade DCIS. An irregular hypoechoic mass with an indistinct and microlobulated margin (13 of 26 [50.0%]) was the most frequent finding in non–high‐grade DCIS. 相似文献
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目的:探讨乳腺导管内癌的超声表现及误诊原因。方法:回顾分析经手术病理证实的17例乳腺导管内癌的超声声像图特征。结果:17例病灶中,超声诊断恶性肿瘤14例,良性病变2例,1例未发现肿块;超声诊断符合率为82.3%。根据文献和本研究中病灶的声像图特征,将17例病变分为5类:实性肿块型(6例),导管扩张型(5例),结构紊乱型(4例),囊性病灶型(1例),其他类型(1例)。结论:乳腺导管内癌的超声表现多样,充分认识乳腺导管内癌的超声声像图特征可减少误诊,结合钼靶及乳腺导管内镜检查可以减少漏诊。 相似文献
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目的:探讨早期乳腺导管癌超声声像图特点,提高超声诊断水平。方法:回顾性分析33例经病理证实为早期乳腺导管癌的超声图像资料。结果:早期乳腺导管癌超声表现复杂,肿瘤大小为9~80mm形态:类圆形8例,分叶状4例,不规则形20例;边界:模糊12例,尚清晰20例;微小钙化斑:未见16例,少量11例,呈满天繁星状5例;后方回声:衰减8例,增强5例,无改变19例。根据肿块二维超声表现,将其分为6种类型。超声诊断准确率81.8%,漏诊1例。结论:超声检查为早期乳腺导管癌有效检查方法。充分认识其超声表现,对正确诊断有一定帮助。 相似文献
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超声与钼靶摄影诊断乳腺导管内癌的对照研究 总被引:13,自引:2,他引:13
目的评价超声、钼靶摄影以及二者综合对乳腺导管内癌的诊断准确性。
方法分析经病理证实的83例乳腺导管内癌的钼靶摄影和超声表现,并比较其诊断准确性。
结果(1)超声表现腺体内低回声实性病变52例(62.7%),导管内实性结节16例(19.3%),囊性病变或乳腺导管扩张7例(8.4%),阴性8例(9.6%);(2)钼靶摄影表现簇状微小钙化53例(63.9%),软组织结节或局部密度增高50例(60.2%),未发现明确病变者9例(10.8%);(3)分类比较超声、钼靶摄影和二者综合分类为可能恶性者分别为47例、53例、67例,2种方法准确率差异无统计学意义(56.6%和63.9%,P=0.169);综合2种方法后诊断准确率高于钼靶摄影(80.7%和63.9%,P〈0.001)。
结论超声和钼靶摄影诊断导管内癌的准确率较低。综合应用2种检查方法可提高诊断准确率。 相似文献
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乳腺照相辅以导丝定位活检对诊断乳腺原位癌的意义 总被引:7,自引:1,他引:7
目的 探讨乳腺X线钼靶照相辅以细针穿刺导丝定位活检技术对提高原位癌诊断率的意义。方法 收集1997—2000年病理确诊的乳腺癌679例;以及近半年来手术或活检病理证实的乳腺癌74例,术前51例行乳腺钼靶照相,其中4例行定位活检。比较两个时期乳腺原位癌的发现率。结果 1997—2000年679例乳癌患者原位癌18例,占乳癌2.7%。近半年来74例乳癌患者中,原位癌4例,发现率为5.4%。比1997—2000年明显增高。结论 乳腺钼靶X线照相及穿刺定位活检技术可以提高原位癌的诊断率。 相似文献
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目的探讨乳腺导管内原位癌(ductal carcinoma in situ,DCIS)和乳腺导管内癌微小浸润(intraductal carcinoma with microinvasion,DCMI)的声像图改变。
方法使用Philips HDI 3000型超声诊断仪分析8例DCIS或DCMI的声像图,并与病理对照。
结果8例均为单发病灶,其中5例形态不规则,3例呈椭圆形;边界均不清晰;内部均呈低回声,其中1例伴有囊变;6例伴有点状强回声;病变后方回声均无改变;5例内部可见少量血流信号。大体标本均未见有包膜。6例病理诊断为DCMI,2例为DCIS,其中分别有5例和1例伴有粉刺状坏死。
结论DCIS及DCMI在声像图上具有一些特点。 相似文献
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Hyo Soon Lim MD Su Jin Jeong MD Ji Shin Lee MD Min Ho Park MD Jung Han Yoon MD Jin Woong Kim MD Jin Gyoon Park MD Heoung Keun Kang MD 《Journal of ultrasound in medicine》2011,30(5):701-705
The purpose of this series was to evaluate the sonographic features of invasive cribriform carcinoma of the breast. Between 2004 and 2010, 3 patients had confirmed invasive cribriform carcinoma of the breast in our institution, and all of them underwent sonography. Sonograms showed masses with an oval (n = 2) or irregular (n = 1) shape, partially microlobulated (n = 2) or well‐circumscribed (n = 1) margins, and a hypoechoic (n = 2) or an isoechoic (n = 1) internal echo texture. Sonographic assessments were classified as Breast Imaging Reporting and Data System category 4 in all 3 cases. Although invasive cribriform carcinoma is a rare breast malignancy, awareness of its sonographic features will be helpful for the diagnosis. 相似文献
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乳腺原位癌的高频超声诊断评价 总被引:1,自引:0,他引:1
目的评价乳腺原位癌的高频超声诊断意义。方法回顾性分析41例乳腺原位癌的高频超声声像图征象,常规记录病变区形态、边界、内部回声、微钙化、后方回声等声像图改变,并与钼靶摄片检查征象(微小钙化、肿块结节影)进行对照分析。结果41例乳腺原位癌中,高频超声检查有阳性发现的共34例,其声像图表现可归纳为以下三型:(1)肿块型(伴或不伴微小钙化)18例;(2)导管型(伴或不伴微小钙化)13例;(3)单纯微钙化型共3例。41例原位癌中钼靶摄片显示有微钙化的29例,占本组病例的71%,高频超声对微小钙化的检出率为69%(20/29)。钼靶显示肿块结节影的有20例,仅占49%。本组病例中,超声诊断提示恶性倾向的有21例,诊断准确率为51%(21/41)。钼靶摄片的诊断准确率为59%,而超声与钼靶相互结合综合判断,诊断准确率可提高至76%。结论在乳腺原位癌的诊断中,高频超声检查既弥补了钼靶摄片的不足,且可以提高钼靶诊断的特异性。超声检查与钼靶摄片的相互结合、相互补充是提高其诊断准确率的关键。 相似文献
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Although rare, breast CLL/SLL should be considered in the differential diagnosis of a breast mass. A high index of suspicion is needed to differentiate this neoplasm from more common breast carcinomas like solid variant of invasive lobular carcinoma. 相似文献
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目的评价钼钯摄影及超声在乳腺导管内癌诊断中的价值。方法回顾性分析156例经手术病理证实的乳腺导管内癌患者,比较其术前钼钯摄影和超声表现和特点。结果乳腺钼钯摄影表现为97例(62.2%)成簇的微小钙化,15例(9.6%)弥漫性微小钙化。乳腺导管造影显示21例(13.5%)出现导管内充盈缺损或截断。超声显示为实性肿块76例(48.7%),囊实性肿块21例(13.5%)。钼钯摄影和超声诊断乳腺导管内癌的准确率分别为87.8%和62.2%。结论乳腺钼钯摄影和超声均为诊断乳腺导管内癌的重要手段,但前者优于后者。两者结合可以提高诊断的准确性。 相似文献
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目的 探讨动态增强MRI诊断无钙化DCIS的价值.方法 回顾性分析129例接受乳腺X线摄影及MR检查并经手术病理证实的DCIS患者,根据X线摄影判定病灶是否存在钙化;比较有、无钙化DCIS病灶形态、早期强化、延迟强化方式、核分级及免疫组织化学指标差异.结果 133个DSIC病灶,48个无钙化,85个有钙化.MRI对无钙... 相似文献
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目的 分析乳腺浸润性导管癌的钼靶X线特征 ,提高影像学诊断水平。方法 3 7例经病理证实的乳腺浸润性导管癌 ,钼靶摄取乳腺轴、斜位片 ,分析其影像学表现。结果 主要X线表现 :3 7例中显示肿块影 3 3例 ,占 89.2 % ;显示毛刺状改变 18例 ,占 48.6% ;细小钙化如精盐样 12例 ,占 3 2 .4% ;所显示肿块较临床触诊扪及为小 2 6例 ,占显示肿块病例的78.8%。结论 乳腺浸润性导管癌在X线上有较特征性表现 ,乳腺钼靶检查是诊断此病最基本的影像学方法 ,有助于临床制定合理的治疗方案。 相似文献
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目的 探讨乳腺浸润性导管癌中表皮钙黏蛋白(E-cadherin,E-cad)的表达及其意义.方法 选取2005年1月-2009年12月的组织病理切块,用免疫组织化学EnVision二步法检测63例乳腺浸润性导管癌(invasiveductal carcinoma,IDC)组织中E-cad的表达情况,设为IDC组;另检测... 相似文献