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1.
Mehmet Giray Ersoz Duygu Kunak Mart Emre Ayintap Leyla Hazar Irfan Botan Gunes Seda Karaca Adiyeke Beysim Dogan 《International ophthalmology》2017,37(4):827-833
Purpose
To investigate whether there is a difference between primary open-angle glaucoma (POAG) patients and control group with regard to choroidal thickness (CT) and the factors influencing CT.Methods
Ninety eyes of 90 patients who were being followed up with POAG and 72 eyes of 72 healthy subjects matched for age and gender were included. Peripapillary retinal nerve fiber layer thickness (RNFLT), peripapillary CT, lamina cribrosa thickness (LCT), and prelaminar tissue thickness (PTT) were measured with spectral-domain optical coherence tomography (SD-OCT) enhanced depth imaging (EDI) in all patients.Results
According to multi-variable linear regression analysis results, the factors influencing CT were found as axial length (AL) (B = ?22.78, p = 0.002), intraocular pressure (IOP) (B = ?7.95, p = 0.001), age (B = ?1.77, p = 0.009), and radial pulse rate (B = 1.42, p = 0.015). A statistically significant relationship was not detected between CT and central corneal thickness, mean deviation value of visual field, cup/disk ratio, RNFLT, LCT, PTT. CT was found significantly thinner in glaucoma group (147.5 ± 61.2 μm) compared to control group (167.1 ± 37.3 μm). However, IOP was found significantly higher (p < 0.001) and pulse rate was found significantly lower (p = 0.021) in POAG group. IOP and pulse rate were considered to have affected CT difference between the groups. In advanced and worser stage patients, there were significant positive correlations between CT and RNFLT in inferior and superior quadrants.Conclusions
In addition to previous studies, IOP and pulse rate were detected to be effective on CT. Further studies are required for determining the whole factors effective on CT and better understanding CT and glaucoma relationship.2.
Sung Wook Park Jeong-Min Hwang 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2015,253(1):135-141
Purpose
The aim of the study was to evaluate the relationship between visual function and retinal nerve fiber layer thickness (RNFLT) determined using Stratus optical coherence tomography (OCT) in patients with autosomal dominant optic atrophy (ADOA).Methods
The study was a retrospective, institutional, and comparative case series. Thirty-six consecutive patients with ADOA and 72 age-matched normal controls were compared with regard to RNFLT, best-corrected visual acuity (BCVA), and visual field.Results
The relative reduction of RNFLT of ADOA patients was most evident in the temporal quadrant (56.8 %), followed by the inferior (35.5 %), superior (27.2 %), and nasal quadrants (26.4 %). In ADOA patients, BCVA decreased with RNFL thinning (p?<?0.001), and was not related to age (p?=?0.210). Papillomacular bundle RNFLT decreased with age throughout the study period of 3.7?±?2.3 years (?3.83?±?9.96 μm, p?=?0.017). The presence of a superotemporal central scotoma (61.1 %) was related to decreased inferotemporal RNFLT (7 and 8 o’clock, p?=?0.016 and p?=?0.036, respectively).Conclusions
The papillomacular bundle RNFL of ADOA is most vulnerable and progressively damaged with age, despite early temporal RNFL loss. Early loss of inferior temporal RNFL in ADOA is related to superotemporal central scotoma.3.
Hasan Basri Arifoglu Bekir Kucuk Necati Duru Orhan Altunel Ahmet Gulhan Mustafa Ozen Bilal Aygun Mustafa Atas 《International ophthalmology》2018,38(1):119-125
Purpose
The aim of this study was to investigate the effect of β-thalassemia minor on choroidal, macular, and peripapillary retinal nerve fiber layer thickness.Methods
To form the sample, we recruited 40 patients with β-thalassemia minor and 44 healthy participants. We used spectral-domain optical coherence tomography to take all measurements of ocular thickness, as well as measured intraocular pressure, axial length, and central corneal thickness. We later analyzed correlations of hemoglobin levels with ocular parameters.Results
A statistically significant difference emerged between patients with β-thalassemia minor and the healthy controls in terms of mean values of subfoveal, nasal, and temporal choroidal thickness (p = 0.001, p = 0.016, and p = 0.010, respectively). Except for central macular thickness, differences in paracentral macular thicknesses between the groups were also significant (superior: p < 0.001, inferior: p = 0.007, temporal: p = 0.001, and nasal: p = 0.005). Also, no statistically significant differences were noted for retinal nerve fiber layer thickness between two groups.Conclusion
Mean values of subfoveal, nasal, temporal choroidal, and macular thickness for the four quadrants were significantly lower in patients with β-thalassemia minor than in healthy controls.4.
Prakadeeswari Gopalakrishnan Aravind Haripriya Periasamy Sundaresan 《International ophthalmology》2018,38(2):599-606
Purpose
Pseudoexfoliation syndrome (PEX) is a late onset disorder of extracellular matrix turnover, associated systemically with cardiovascular and cerebrovascular disease. To evaluate the suggested association of polymorphisms of homocysteine metabolism genes MTHFR (rs1801131, rs1801133) and MTHFD1 (rs8006686) with PEX.Methods
A case–control association study was undertaken, comprising a total of 1472 individuals including 860 unrelated PEX cases and 612 ethnic-matched cataract controls (CC). All the study subjects were genotyped for three SNPs using the TaqMan allelic discrimination assay. Association and statistical analysis were performed with PLINK 1.07 and STATA 11.1.Results
Among the three SNPs genotyped, MTHFR polymorphisms did not exhibit significant association with PEX (rs1801131; p = 0.549, rs1801133; p = 0.408). The intronic SNP rs8006686 showed nearly significant association (p = 0.069), and however did not remain significant after Bonferroni correction.Conclusion
Our study suggests no significant genetic association of MTHFR (rs1801131, rs1801133) and MTHFD1 (rs8006686) polymorphisms in South Indian PEX patients.5.
Tarannum Mansoori Jayanthi Sivaswamy Jahnavi Sai Gamalapati Nagalla Balakrishna 《International ophthalmology》2018,38(3):967-974
Purpose
To analyse the expansion of radial peripapillary capillary (RPC) network with optical coherence tomography angiography (OCT-A) in normal human eyes and correlate RPC density with retinal nerve fibre layer thickness (RNFLT) at various distances from the optic nerve head (ONH) edge.Methods
Fifty eyes of 50 healthy subjects underwent imaging with RTVue XR-100 Avanti OCT. OCT-A scans of Angio disc (6 × 6 mm) and Angio retina (8 × 8 mm) were combined to create a wide-field montage image of the RPC network. RPC density and RNFLT was calculated at different circle diameter around the ONH, and their correlation was measured.Results
In the arcuate region, RPC was detected as far as 8.5 mm from the ONH edge, but not around the perifoveal area within 0.025 ± 0.01 mm2. The mean RPC density (0.1556 ± 0.015) and RNFLT (245.96 ± 5.79) were highest at 1.5 mm from ONH margin, and there was a trend in its decline, in a distance-dependent manner, with the least density at 8.5 mm (all P < 0.0001). Highest RPC density was noted in the arcuate fibre region at all the distances. Overall mean RPC density correlated significantly (P < 0.0001) with the overall mean RNFLT.Conclusions
Wide-field montage OCT-A angiograms can visualize expansion of the RPC network, which is useful in obtaining information about various retinal disorders. The results obtained support the hypothesis that the RPC network could be responsible for RNFL nourishment.6.
Purpose
To compare the visual acuity outcomes, contrast sensitivity function (CS) and reading ability in patients with bilateral multifocal intraocular lenses and patients with bilateral monofocal lenses.Setting
Vizyon Eye Center, Denizli, Turkey.Design
Comparative case series.Methods
Consecutive bilateral cataract patients having implantation of Acriva Reviol MFM 611 multifocal IOLs (Group A) or Acriva BB UD 613 monofocal IOLs (Group B) were included. Parameters analyzed 6 months postoperatively included monocular uncorrected distance (UDVA), binocular uncorrected intermediate (UIVA), binocular uncorrected near (UNVA), CS and bilateral reading performance using MN Read.Results
The study evaluated 42 eyes in Group A and 40 eyes in Group B. There were no statistically significant differences in UDVA between two groups postoperatively (p = .39). Binocular UIVA and binocular UNVA are better in Group A (p = .00, p = .00). Under photopic and scotopic conditions, contrast sensitivity results were decreased in Group A, especially at high spatial frequencies. No statistically difference were found in reading acuity, critical print size and maximum reading speed between two groups (p = .57, p = .62, p = .22).Conclusions
This study concludes that multifocal lenses are reliable and efficient replacements for reading glasses since they significantly improve the vision for near or intermediate distance activities.7.
AyşeÖzköse Çiçek Necati Duru Zeynep Duru Orhan Altunel Arzu Seyhan Karatepe Haşhaş Hasan Basri Arifoğlu Bedirhan Alabay Mustafa Ataş 《International ophthalmology》2017,37(4):843-848
Purpose
The purpose of the study was to evaluate the effect of Valsalva maneuver (VM) on choroidal thickness.Methods
All the volunteers underwent a detailed opthalmic examination. Third-generation Spectralis OCT device (software version 5.6.3.0; Spectralis OCT, Heidelberg Engineering, Dossenheim, Germany) was used for assessment. Subfoveal and perifoveal CT of all volunteers were measured by using EDI-OCT technology. Perifoveal CT was measured 1500 µm nasally and 1500 µm temporally apart from the foveal center. The measurements were repeated while volunteers were performing VM.Results
Sixty-four eyes of 32 healthy volunteers were assessed. The volunteers were aged 29–50. The mean age was 32.8 ± 6.6 years. Choroidal thickness measurements differed with statistical significance between resting position and VMin all regions (p < 0.001). While mean subfoveal CT was 350.64 ± 87.73 µm during resting position, it was 369.95 ± 90.12 µm during VM (p < 0.001). While mean nasal CT was 292.14 ± 81.67 µm during resting position, it was 305.46 ± 85.80 µm during VM (p < 0.001). While mean temporal CT was 325.93 ± 80.91 µm during resting position, it was 343.21 ± 81.53 µm during VM (p < 0.001).Conclusions
We found statistically significant increase in choroidal thickness during the VM in healthy volunteers. This result might be important for future studies researching autoregulation of choroidal and retinal blood flow in physiologic and pathologic conditions. Also, our study is noteworthy to stand out the errors in EDI-OCT measurements caused by unintentional breath holding of patients.8.
Norma Fariña Margarita Samudio Letizia Carpinelli Martin M. Nentwich Herminia Mino de Kaspar 《International ophthalmology》2017,37(4):819-825
Purpose
Coagulase-negative staphylococci have been reported to be the most frequent cause of bacterial postoperative endophthalmitis. Biofilm formation is the major virulence factor of Staphylococcus epidermidis and is often associated with methicillin resistance. This study aims at evaluating the presence of biofilm-producing and methicillin resistance genes (mecA) in S. epidermidis.Methods
S. epidermidis isolated from clinically infected sites (group 1) and from normal human conjunctiva (group 2) were studied. All the isolates were tested for their ability to produce biofilm by the conventional Christensen´s method and the presence of mecA by PCR using the 22-mer oligonucleotides as primers.Results
In total 20 isolates from group 1 and 22 from group 2 were studied. Biofilm and mecA were detected in 15 (75 %) and in 14 (70 %) in group 1 as compared to 8 (36.3 %) and 4 (18.2 %) in group 2 (p = 0.016). Simultaneously, biofilm production and presence of mecA genes were observed in 13/20 (65.0 %) in group 1, and 4/22 (18.2 %) in group 2 (p = 0.002). Multi-resistance was observed in 55 % in group 1 and 9 % in group 2 (p = 0.002); 57 % of the biofilm-producing strains was multi-resistant in contrast to none of the non-producing strains. In all multi-resistant strains, biofilm production was seen.Conclusions
Biofilm formation capacity was widely distributed, particularly among mecA (+) S. epidermidis strains, which also displayed a high diversity of antibiotic resistance profiles.9.
Marlon M. Maducdoc Asghar Haider Angèle Nalbandian Julie H. Youm Payam V. Morgan Robert W. Crow 《International ophthalmology》2017,37(2):433-439
Background
With the increasing prevalence of electronic readers (e-readers) for vocational and professional uses, it is important to discover if there are visual consequences in the use of these products. There are no studies in the literature quantifying the incidence or severity of eyestrain, nor are there clinical characteristics that may predispose to these symptoms with e-reader use.Purpose
The primary objective of this pilot study was to assess the degree of eyestrain associated with e-reader use compared to traditional paper format. The secondary outcomes of this study were to assess the rate of eyestrain associated with e-reader use and identify any clinical characteristics that may be associated with the development of eyestrain.Methods
Forty-four students were randomly assigned to study (e-reader iPAD) and control (print) groups. Participant posture, luminosity of the room, and reading distance from reading device were measured during a 1-h session for both groups. At the end of the session, questionnaires were administered to determine symptoms.Results
Significantly higher rates of eyestrain (p = 0.008) and irritation (p = 0.011) were found among the iPAD study group as compared to the print ‘control’ group. The study group was also 4.9 times more likely to report severe eyestrain (95 % CI [1.4, 16.9]). No clinical characteristics predisposing to eyestrain could be identified.Conclusions
These findings conclude that reading on e-readers may induce increased levels of irritation and eyestrain. Predisposing factors, etiology, and potential remedial interventions remain to be determined.10.
Purpose
We performed a prospective cohort study to evaluate the effectiveness of disc synoptoscope on binocularity in patients with abnormal binocular vision.Methods
39 eligible subjects were recruited for visual therapy with disc synoptoscope in treatment group and 38 were just observed as control.Results
Simultaneous perception in treatment group was better than controls at 6-month visit (p < 0.05). Fusional amplitude improved in treatment group but decreased in control group at 3- and 6-months visits (p < 0.001). Near and distance stereopsis in treatment group were better than controls at 3- and 6-months (p < 0.05). The improvements of monocular and binocular acuity in treatment group were better than controls at 3- and 6-months (p < 0.05). Postoperative recurrence rate in treatment group was lower than controls (p < 0.05).Conclusion
Visual therapy with disc synoptoscope is effective in improving short-term binocular vision for the patients with abnormal binocular vision; disc synoptoscope could serve as an effective home-based visual therapy instrument.11.
Yohei Takahashi Hideki Koizumi Taiji Hasegawa Takahiko Izumi Ichiro Maruko Shozo Sonoda Taiji Sakamoto Tomohiro Iida 《Japanese journal of ophthalmology》2018,62(5):576-583
Purpose
To evaluate and compare the intrachoroidal structures of eyes with typical neovascular age-related macular degeneration (AMD) with those of eyes with polypoidal choroidal vasculopathy (PCV).Study design
Retrospective and comparative case series.Methods
Eighty-four treatment-naïve eyes of 84 patients (22 women and 62 men) with typical neovascular AMD or PCV located in the subfoveal region were studied. Cross-sectional images of the retina and choroid were obtained by swept-source optical coherence tomography (SS-OCT). The horizontal SS-OCT images were analyzed by a manual delineation technique and by a binarization method.Results
Thirty-nine eyes with typical neovascular AMD and 45 eyes with PCV were studied. Although the subfoveal choroidal thickness (SCT) did not differ significantly between the 2 subtypes (255.1?±?86.7 µm in typical neovascular AMD and 289.2?±?116.5 µm in PCV, P?=?0.29), the ratio of the large choroidal vessel layer (LCVL) thickness to the SCT was significantly larger in the eyes with PCV than in the eyes with typical neovascular AMD (0.863?±?0.084 vs 0.803?±?0.125, P?=?0.023). The binarization method did not find significant differences in the choroidal structure between the 2 subtypes. Multivariate logistic regression analyses found the ratio of the LCVL thickness to the SCT to be the only significantly different factor between typical neovascular AMD and PCV (P?=?0.035).Conclusion
The intrachoroidal structures of typical neovascular AMD and PCV eyes differ significantly. In eyes with PCV, there seemed to be a greater dilation of the large choroidal vessels.12.
Aysun Sanal Dogan Mutlu Acar Mustafa Kosker Nese Arslan Canan Gurdal 《International ophthalmology》2018,38(1):53-57
Purpose
To evaluate whether the corneal epithelial thickness (CET) maps obtained by optical coherence tomography (OCT) of the congenital myogenic eyelid ptosis differ from controls.Methods
CET maps of 13 patients with congenital myogenic eyelid ptosis (m/f = 9/4; mean age 20.5 ± 7.5) and randomly selected one eye of 13 controls (m/f = 7/6; mean age 21.5 ± 6.5) were investigated. Three pachymetry scans of each eye were performed by OCT (RTVue-XR, Optovue Inc., USA), and the scan with the highest signal strength index was selected for the analysis.Results
In ptosis group: Minimum corneal epithelial thickness was thinner (p = 0.029), standard deviation of thickness was higher (p = 0.039), the negative of min–max values were higher (p = 0.007). This difference was originating from the significant thinness of the superior sectors (S, SN, ST) of the corneal epithelium than the inferior counterparts (I, IT, IN) (p = 0.001, p = 0.017, p = 0.002), respectively. There was no difference regarding total corneal thickness measurements.Conclusions
The mechanic effects of ptotic eyelid to the ocular surface may reshape the corneal epithelium, which can be objectively detected by OCT.13.
14.
Purpose
To investigate the dry eye after small incision lenticule extraction (SMILE) and explore the correlations between changes in the tear film stability, the tear secretion and the corneal surface regularity.Methods
Sixty-two eyes of 22 men and 13 women who underwent SMILE were included in this study. Corneal topography was measured to assess the index of surface variance (ISV) and the index of vertical asymmetry (IVA). Dry eye tests including subjective symptom questionnaire, tear breakup time (TBUT), corneal fluorescein staining and Schirmer’s test (ST) were evaluated before and at 1 and 6 months postoperatively.Results
TBUT was found to be significantly decreased from 9.8 ± 3.4 s preoperatively to 7.4 ± 3.8 s at 1 month and 6.5 ± 3.6 s at 6 months (both P < 0.001). There was a significant decrease in ST at 1 month postoperatively (P = 0.012); however, ST returned to baseline by 6 months (P = 0.522). Both ISV and IVA significantly increased after the surgery (all P < 0.001). In addition, the changes in TBUT were negatively correlated with the increases in ISV and IVA (r = ?0.343, P = 0.006 and r = ?0.311, P = 0.014, respectively).Conclusions
Patients undergoing SMILE might develop a short-TBUT type of dry eye. Corneal surface regularity indices might be helpful in the assessment of tear film stability following SMILE procedure.15.
Nicola Cardascia Carmela Palmisano Tersa Centoducati Giovanni Alessio 《International ophthalmology》2017,37(5):1127-1131
Purpose
The purpose of the study was to assess adjuvant treatment with topical nonsteroidal anti-inflammatory drugs (NSAIDs) (0.9 % bromfenac, 0.1 % nepafenac, 0.5 % indomethacin, or 0.1 % diclofenac) in addition to topical steroidal treatment with 0.1 % dexamethasone and 0.3 % netilmicin for prevention of cystoid macular edema (CME) after uneventful small incision cataract extraction with foldable intraocular lens (IOL) implantation.Setting
Institute of Ophthalmology, Department of Scienze Mediche di Base, Neuroscienze ed Organi di Senso, Aldo Moro University, Policlinico Consorziale di Bari, Bari, Italy.Design
A retrospective 6-month single center study.Methods
Patients were divided into groups according to treatment with topical drugs for 2 weeks, after phacoemulsification with foldable IOL implantation. CME incidence was evaluated by assessing retinal foveal thickness changes using spectral domain optical coherence tomography. All patients were treated with a fixed combination of dexamethasone and netilmicin, and some patients were additionally treated with NSAIDs (bromfenac, nepafenac, indomethacin, or diclofenac).Results
Fourteen patients were treated with bromfenac, 15 with nepafenac, 12 with indomethacin, and 14 with diclofenac; ten patients were treated with dexamethasone and netilmicin alone. At the end of the follow-up, macular thickness, evaluated at 1-week post-surgery, was reduced only in the group treated with nepafenac (?1.3 %, p = 0.048), was increased in the group treated with dexamethasone and netilmicin alone (+4.3 %, p = 0.04), and did not change in the groups treated with bromfenac (?1.1 %, p = 0.3), indomethacin (+0.1 %, p = 0.19), or diclofenac (+1.2 %, p = 0.74). There were no side effects in any group.Conclusions
Topical treatment with nepafenac, bromfenac, and indomethacin enhanced the efficacy of steroids to reduce postoperative macular edema. Diclofenac did not improve steroids efficacy.16.
Cecilio Velasco-Barona Guadalupe Cervantes-Coste Erick Mendoza-Schuster Claudia Corredor-Ortega Nadia L. Casillas-Chavarín Alejandro Silva-Moreno Manuel Garza-León Roberto Gonzalez-Salinas 《International ophthalmology》2018,38(3):951-957
Purpose
To compare the biometric measurements obtained from the Verion Image-Guided System to those obtained by auto-refracto-keratometer in normal eyes.Methods
This is a prospective, observational, comparative study conducted at the Asociación para Evitar la Ceguera en México I.A.P., Mexico. Three sets of keratometry measurements were obtained using the image-guided system to assess the coefficient of variation, the within-subject standard deviation and intraclass correlation coefficient (ICC). A paired Student t test was used to assess statistical significance between the Verion and the auto-refracto-keratometer. A Pearson’s correlation coefficient (r) was obtained for all measurements, and the level of agreement was verified using Bland–Altman plots.Results
The right eyes of 73 patients were evaluated by each platform. The Verion coefficient of variation was 0.3% for the flat and steep keratometry, with the ICC being greater than 0.9 for all parameters measured. Paired t test showed statistically significant differences between groups (P = 0.0001). A good correlation was evidenced for keratometry values between platforms (r = 0.903, P = 0.0001 for K1, and r = 0.890, P = 0.0001). Bland–Altman plots showed a wide data spread for all variables.Conclusion
The image-guided system provided highly repeatable corneal power and keratometry measurements. However, significant differences were evidenced between the two platforms, and although values were highly correlated, they showed a wide data spread for all analysed variables; therefore, their interchangeable use for biometry assessment is not advisable.17.
Isil Sayman Muslubas Mumin Hocaoglu Mehmet Giray Ersoz Serra Arf Murat Karacorlu 《International ophthalmology》2018,38(3):1035-1042
Purpose
To evaluate subfoveal choroidal thickness (SCT) in cases with chronic rhegmatogenous retinal detachment (RRD), before and after pars plana vitrectomy, and cases with acute RRD using optical coherence tomography.Methods
This retrospective study included 24 eyes with chronic RRD and 26 eyes with recent-onset RRD. Best corrected visual acuity, intraocular pressure, and SCT were measured and compared between the two groups. Of 24 eyes with chronic RRD, 11 had primary pars plana vitrectomy. Measurements of operated and fellow eyes were also compared before surgery and 1 week, 1 and 3 months after surgery.Results
The preoperative mean SCT in eyes with chronic RRD was 342.6 ± 111.7 µm and in fellow eyes 342.4 ± 116.7 µm (P = 0.83) and in eyes with acute RRD was 346.2 ± 51 µm and in fellow eyes 262.7 ± 46.8 µm (P < 0.001). There was also no significant change in SCT between baseline before surgery and 3 months after surgery in eyes with chronic RRD (P = 0.20).Conclusion
No significant difference was found in the mean SCT between affected and fellow eyes in chronic RRD. This may be related to intraocular inflammation, which is more limited in chronic than in acute RRD. There was also no significant difference in the SCT in eyes with chronic RRD between the operated and fellow eyes after surgery. It may be concluded that vitrectomy does not affect choroidal thickness.18.
Purpose
Our aim was to compare optic disc parameters, retinal nerve fiber (RNFL) and macular ganglion cell layers between children and adolescents with diabetes mellitus (type 1) and healthy controls.Methods
Sixty-three eyes of 63 pediatric diabetic patients without diabetic retinopathy and 44 eyes of 44 healthy controls were included in this cross-sectional and comparative study. Diabetic and control groups were similar in the aspect of age, gender and refractive error. Measurements of optic disc parameters (i.e., rim area, disc area, cup-to-disc ratio, cup volume), thickness of RNFL and macular ganglion cell—inner plexiform layers (GCL + IPL) were taken with the spectral domain optical coherence tomography.Results
There were not statistically significant differences between the diabetic patients and healthy controls in terms of intraocular pressure (p = 0.14), retinal nerve fiber layer thickness (p = 0.61), rim area (p = 0.92), disc area (p = 0.10), vertical cup-to-disc ratio (p = 0.16), cup volume (p = 0.13), and average macular GCL + IPL thickness (p = 0.43). On the other hand, binocular RNFL thickness symmetry percentage was statistically significantly different in the diabetic and control groups (p = 0.01).Conclusion
Diabetic children and adolescents without diabetic retinopathy have more binocular RNFL thickness asymmetry compared to healthy controls.19.
Zhaotian Zhang Yantao Wei Xintong Jiang Shaochong Zhang 《International ophthalmology》2018,38(4):1505-1513
Purpose
To investigate the use of 27-gauge pars plana vitrectomy (PPV) with short-term tamponade of perfluorocarbon liquid (PFCL) for repair of giant retinal tears (GRT).Methods
Retrospective case series study. Consecutive patients with GRT were treated with 27-gauge PPV and short-term tamponade of PFCL for 7–10 days. PFCL was completely removed with a secondary surgery.Results
Twenty-three eyes of 23 patients were included. All the patients achieved primary anatomic success. Preoperative logarithm of the minimum angle of resolution (logMAR) BCVA was 1.59 ± 0.58 (Snellen 20/778). Five (21.7%), nine (39.1%), eleven (47.8%) and fifteen (65.2%) eyes experienced vision improvement at the Month-1, Month-3, Month-6 and final follow-ups, respectively. The final logMAR BCVA was 0.84 ± 0.51 (Snellen 20/138), being statistically better than the preoperative one (P < 0.001). Surgical complications included foreign body response (n = 7), transient elevated intraocular pressure (n = 5), cataract formation/deterioration (n = 11) and posterior capsule opacity (n = 16).Conclusions
27-Gauge PPV with short-term tamponade of PFCL is safe and effective for the repair of GRT. Side effects of the surgery mainly included foreign body response, transient elevated intraocular pressure, cataract formation/deterioration and posterior capsule opacity.20.