透刺法治疗肱骨外上髁炎34例

目的 观察透穴法治疗肱骨外上髁炎疗效.方法 78例患者随机分成透刺法治疗组34例和传统针刺法组34例,治疗2个疗程后观察比较两组疗效.观察组:取穴:曲池,阿是穴(肱骨外上髁处)采用透穴法.对照组:取曲池、手三里,阿是穴、采用直刺.结果 透刺法与侍统针刺法疗效比较,差异有显著性意义(P<0.05).结论 透穴法治疗肱骨外上髁炎,疗效确切,安全实用,值得临床推广.优于传统针刺效果.     

电针结合TDP治疗仪治疗肱骨外上髁炎临床观察

目的观察电针结合TDP治疗仪治疗肱骨外上髁炎的临床疗效。方法 60例肱骨外上髁炎患者被随机分为两组。治疗组采用电针结合TDP电磁波治疗仪治疗,对照组采用穴位注射治疗。结果治疗组总有效率高于对照组(P0.05);治疗后两组VSA积分呈下降趋势,治疗组下降更明显(P0.05)。结论采用电针结合TDP治疗仪治疗肱骨外上髁炎疗效确切,操作简单,安全。     

综合治疗肱骨外上髁炎39例

目的:寻找治疗肱骨外上髁炎有效的治疗方法。方法:采用电针、局部封闭配合神灯综合治疗肱骨外上髁炎39例(治疗组),并与局部封闭配合超短波治疗28例(对照组)作对比,判断分析结果。结果:治疗组与对照组之间的疗效差异有显著性意义(P<0.05),治疗组的疗效优于对照组。结论:采用电针、局部封闭配合神灯综合治疗肱骨外上髁炎疗效显著,值得临床推广应用。     

针刀配合手法治疗肱骨外上髁炎疗效观察

目的观察针刀配合手法治疗肱骨外上髁炎的临床疗效,探索治疗肱骨外上髁炎的有效方法。方法将86例患者随机分为治疗组和对照组,治疗组46例采用针刀配合手法治疗,对照组采用针刺配合按摩治疗,2个疗程后观察疗效。结果治疗组的治愈率及总有效率显著高于对照组,两组比较,差异有高度统计意义(P0.01)。结论针刀配合手法治疗肱骨外上髁炎疗效显著,是安全有效的治疗方法。     

火针治疗肱骨外上髁炎疗效观察

目的 观察火针治疗肱骨外上髁炎的临床疗效.方法 将60例肱骨外上髁炎的患者随机分成治疗组和对照组,各30例,治疗组采用火针疗法治疗,对照组采用普通针刺方法治疗.结果 治疗组总有效率93.3%,对照组总有效率76.7%(P<0.05),2组治后的VAS评分、肘部压痛积分均存在统计学意义(P<0.05).结论 火针疗法治疗肱骨外上髁炎,能温通经脉,使气血运行顺畅,通则不痛.     

中西医结合治疗肱骨外上髁炎136例临床观察

目的:观察中西医结合治疗肱骨外上髁炎的临床疗效.方法:将136例肱骨外上髁炎患者随机分为两组,治疗组给予中药外敷结合封闭治疗;对照组单纯给予封闭治疗,3周后观察疗效.结果:两组临床治疗总有效率比较,治疗组明显优于对照组(P＜0.05).结论:中西医结合治疗肱骨外上髁炎临床疗效明显,有推广应用价值.     

针刺结合火针治疗肱骨外上髁炎疗效观察

为观察针刺结合火针治疗肱骨外上髁炎的临床疗效,将62例患者随机分成针刺结合火针组(观察组)及针刺组(对照组),观察组采用针刺患肢曲池、手三里、外关、合谷及压痛点,并用火针点刺肱骨外上髁局部痛点;对照组单纯针刺,选穴以及针法、疗程完全同观察组;治疗2个疗程后评定疗效.结果 ,观察组治愈率87.5%,总有效率100%;对照组治愈率63.3%,总有效率86.7%;两组差异有统计学意义(P<0.05).认为针刺结合火针方法治疗肱骨外上髁炎效果较佳.     

经筋刺血法配合运动疗法治疗肱骨外上髁炎40例

目的:比较经筋刺血法配合运动疗法治疗肱骨外上髁炎的临床疗效。方法:将80例符合肱骨外上髁炎诊断、纳入、排除标准的患者随机分配为治疗组(经筋刺血法配合运动疗法)和对照组(常规针刺疗法),每组各40例。2组均在治疗前、治疗3 w后观察整体疗效及VAS疼痛积分、Mayo肘关节功能评估指数(MEPS)。结果:治疗组的有效率为92.5%,显愈率为82.5%;对照组的有效率为82.5%,显愈率为65.0%,2组疗效差异有统计学意义(P0.05);2组均能降低VAS疼痛积分及改善Mayo肘关节功能,但治疗组VAS疼痛积分及Mayo肘关节功能改善情况较对照组明显(P0.01)。结论:经筋刺血法治疗肱骨外上髁炎疗效显著,与常规针刺法治疗肱骨外上髁炎相比优势明显,疗效突出。     

肘关节拍打法联合西医常规治疗肱骨外上髁炎38例临床观察

目的观察肘关节拍打法联合西医常规治疗肱骨外上髁炎的临床疗效。方法将76例肱骨外上髁炎患者随机分为治疗组和对照组,各38例。对照组给予布洛芬缓释胶囊口服联合中药外敷治疗,治疗组给予布洛芬缓释胶囊口服联合肘关节拍打法治疗,连续治疗1月后比较2组的Mayo肘关节功能评分及临床疗效。结果对照组总有效率为78.94%,治疗组为89.47%,2组比较差异有统计学意义(P0.05);治疗后2组Mayo肘关节功能评分均显著升高,与同组治疗前比较差异均有统计学意义(P0.05或P0.01),且治疗组升高更显著,2组治疗后比较差异有统计学意义(P0.05)。结论肘关节拍打法联合西医常规治疗肱骨外上髁炎临床疗效显著,可明显改善肱骨外上髁炎患者的临床症状,依存性较高,值得临床推广。     

电针配合康复训练治疗肱骨外上髁炎临床观察

目的观察电针配合康复训练治疗肱骨外上髁炎的临床疗效。方法 60例肱骨外上髁炎患者随机分为两组。治疗组30例采用电针结合康复训练,对照组30例采用温针灸治疗,疗程结束后进行疗效评定。结果治疗组总有效率优于对照组(P0.05)。治疗后两组mayo肘关节功能评分呈上升趋势,治疗组上升更明显(P0.05);与对照组治疗后比较,差异具有统计学意义(P0.05)。结论电针配合康复训练可作为治疗网球肘的一种行之有效的方法,值得在临床上广泛推广。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.