毒隐翅虫成虫活动规律与隐翅虫皮炎关系的观察

隐翅虫皮炎(Dermatitis Peaderus)或称“甲虫皮炎”是人体皮肤接触毒隐翅虫虫体毒液而引起的一种炎症.我们于1983-1985年对南宁市毒隐翅虫的主要种类及成虫发生规律与隐翅虫皮炎发生的关系作了一些观察,现将结果报告如下.     

392例隐翅虫皮炎暴发调查

对十堰市某制鞋厂暴发的一起急性隐翅虫皮炎进行调查,分析其临床特点并找出病因。对该厂所有员工进行现场体检,记录发病情况,并以厂区及周围环境和员工住宿条件进行调查。对现场捕捉到的虫体带回华中科技大学同济医学院寄生虫教研室进行鉴定。根据临床特点此次暴发急性皮炎被诊断为隐翅皮炎。病原体鉴定为毒隐翅虫。在总共420例员工中共有392例发生隐翅虫皮炎,发生率为93.33%。管理人员和工人的发育率分别为42.86%和96.84%。     

自制莲黄苏打液治疗隐翅虫皮炎394例

1999年9月10月,我院新建学生宿舍区出现大量毒隐翅虫(Paederus),从而引起隐翅虫皮炎(Paederus dermatitis)的爆发流行.在学校整治宿舍周边环境的同时,我教研室利用半边莲(Lobelia cknensis Lour)、藤黄(Garcinia henaburyiHook)等配制的莲黄苏打液用于治疗学生的隐翅虫皮炎,取得了较好的疗效,特报道如下:     

昆虫、寄生虫性皮肤病

荆州职院毒隐翅虫皮炎1106例流行病学资料分析;隐翅虫皮炎诱发急性泛发性发疹性脓疱病1例;疥疮62例误诊分析;长效驱蚊霜野外现场驱避效果评价;新疆毒蜘蛛咬伤中毒24例诊治及预防体会     

上海郊区隐翅虫皮炎34例临床分析

目的了解隐翅虫皮炎的临床特征方法对34例门诊就诊的隐翅虫皮炎患者进行回顾性临床分析结果患者均为郊区人士，男19例，女15例，平均年龄32岁，晨起发病14例，傍晚发病20倒结论隐翅虫皮炎发病有季节性，以暴露部位多见。     

隐翅虫皮炎1724例临床分析

目的　总结分析隐翅虫皮炎患者的临床特征及其意义。方法　统计分析 2 0 0 0年 2 0 0 3年来本科就诊的 172 4例隐翅虫皮炎患者临床资料。结果　隐翅虫皮炎发病时间跨度大约为 2 3 9天 ,每年 8,9,10月份为发病高峰期。结论　本组隐翅虫皮炎患者的临床特征与文献报道一致 ,但其发病时间及发病高峰期有所不同。     

隐翅虫皮炎134例临床分析

目的分析本地区隐翅虫皮炎的临床特点，为防治该病提供依据。方法对134例患者的临床资料进行回顾性分析。结果本地区隐翅虫皮炎为散发，男略多于女，以青壮年居多，发病高峰为5月和9月，头面部最易受累，特征性损害为水肿性红斑上有丘疹、水疱等。误诊率达36．57％。结论本地区隐翅虫皮炎的临床表现、发病季节与其他地区略有差别，应提高医生对该病的认识水平，减少误诊率，并应提高户外工作者及集体住宿者的防护意识。     

隐翅虫皮炎71例误诊分析

正隐翅虫皮炎是春、夏、秋季常见皮肤病,如果临床经验不足、或皮损不典型也常被误诊为其他皮肤病,现将我科收集整理的被误诊的71例病例进行归纳总结、分析如下。1临床资料1.1一般资料71例误诊的隐翅虫皮炎病例均为外院误诊,来我科就诊后确诊的2015年至2016年门诊病例,诊断均符合冉玉平~([2])隐翅虫皮炎临床皮疹。其中男53例,女18例,(5～10)岁8例,     

隐翅虫皮炎发病机理的探讨

1986年5月至1987年10月,我科诊洽500例隐翅虫皮炎患者,现结合其临宋资料和实验观察,对隐翅虫支炎的发病机理提出初步探讨.     

隐翅虫皮炎364例报告

隐翅虫皮炎３６４例报告郭仰霖，曾凡伟，李玉珍福建省上杭县卫生防疫站（邮政编码３６４２００）１９９３年７～８月我县发生隐翅虫皮炎近千例。我们随机对市区和郊区３６４例患者进行调查分析，报告如下。一般资料３６４例中男２６７例，女９７例，年龄３～６４岁。郊区...     

Bullous contact dermatitis caused by self-applied crushed Paederus fuscipes for the treatment of vitiligo

Paederus dermatitis is a linear, blistering contact dermatitis caused by pederin, a potent vesicant agent that is contained in insects belonging to the genus Paederus. This form of dermatitis usually occurs accidentally in those who have contact with this insect during the summer season. We report a peculiar case of a patient developing severe chemical burnlike lesions after application to her skin of many crushed Paederus fuscipes that she collected from the soil of a riverbank in the early spring for the treatment of her vitiligo.     

Paederus dermatitis in Egypt: a clinicopathological and ultrastructural study

Background Outbreaks of paederus dermatitis (PD) have been observed in different parts of the world, yet the histopathological and ultrastructural changes and their relationship to pederin toxin have not been described. Objective To describe the clinical presentations of PD in Egypt and to study the effects of pederin toxin on the skin by evaluating the histopathological and ultrastructural changes of some representative cases. Methods One hundred and thirteen patients with PD were studied clinically and epidemiologically. Skin biopsies were taken from 40 patients for histopathological examination and from 20 patients for electron microscopic (EM) examination. Results Clinically, the most common presentation comprised erythematous plaques with micropustules. Blisters exhibited a linear configuration in 40% of the patients and kissing lesions were observed in 13%. Multiple lesions occurred in 78% of the patients and the face was the most commonly involved site (48%). The insect was identified as Paederus alfierii. Histopathological examination revealed features of acute irritant dermatitis in the upper epidermis. Mitotic figures and apoptotic changes such as chromatin condensation and DNA fragmentation were identified in the basal and suprabasal layers. These features were confirmed by EM. Conclusions Clinical, histopathological and, for the first time, ultrastructural characteristics of paederus dermatitis are described. The pathological abnormalities of the upper epidermis are caused by the irritant effect of pederin toxin. The presence of apoptosis within the lower epidermis can be related to this toxin, a point that needs further research, hoping for its future implications in the management of hyperproliferative disorders.     

Paederus fuscipes dermatitis. A histopathological study

Paederus fuscipes (PF) dermatitis is a self-healing blistering disorder of the skin caused by a small insect belonging to genus Paederus, family Staphylinidae, order Coleoptera. Crushing PF on the skin causes acute dermatitis within 24 hours, corresponding in shape and dimensions to the area affected by the substance released (pederin). The acute vesicular lesions become crusted and scaly within a few days and heal completely in 10-12 days, with a transitory postinflammatory hypercromic patch. Twenty consecutive cases of PF dermatitis at different stages were studied histologically by routine light microscopy. The pederin causes a spectrum of histopathologic changes ranging from acute epidermal necrosis and blistering in acute stages, to marked acanthosis with mitotic figures in the late stages. PF dermatitis is an entomological model of irritant contact dermatitis, having histopathologic features of intraepidermal and subepidermal blistering, epidermal necrosis and acantholysis. The presence of some acantholytic foci, relatively far from the foci of clinically involved skin, in four of the cases considered suggests a possible role of pederin in inducing acantholysis indirectly. Acantholysis is probably caused by the release of epidermal proteases.     

Irritant bullous contact dermatitis caused by a rove beetle: An illustrated clinical course

A 26‐year‐old Australian female traveller in Sierra Leone presented with an irritant bullous contact dermatitis consistent with paederus dermatitis. The lesions were treated with a potent topical corticosteroid with good effect. The affected area resolved in 6 weeks and hyperpigmention persisted for months until complete resolution. This dermatitis occurs when beetles of the genus Paederus (rove beetles) are crushed on the skin, releasing pederin. The same dermatitis ensues with Australian Paederus species. Serial clinical photographs are presented which will aid Australian dermatologists in the diagnosis of this dermatitis, which presents in regional Australian patients and returned overseas travellers.     

An outbreak of 268 cases of Paederus dermatitis in a toy-building factory in central China

Objective  To evaluate the clinical features of and to identify the pathogen responsible for an outbreak of acute dermatitis in a toy-building factory in Chibi city, central China.
Methods  Physical examinations were carried out on all the factory staff. Records were made. The factory district, its surrounding environment and the accommodation conditions were investigated. The insects collected in the area were identified by a parasitologist at the Department of Parasitology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan.
Results  Two hundred and sixty-eight cases of Paederus dermatitis were diagnosed in a total of 316 staff at the toy-building factory. The total incidence rate was 84.81%. The incidence rates in administrators and workers were 43.75% and 87%, respectively. The face and neck were the most common sites of involvement. The most common lesions consisted of linear erythema and papulopustules. In 71.27% of patients, more than one lesion was present.
Conclusion  This outbreak of acute dermatitis was diagnosed as Paederus dermatitis caused by Paederus fuscipes . The favorable environment, lighting, humidity, and poor accommodation may have been responsible for the outbreak. Increased public awareness of this condition may decrease the incidence of Paederus dermatitis.     

New and re-emerging cutaneous infectious diseases in Latin America and other geographic areas

Due to environmental factors and inadequate public health measures in many developing countries, new tropical infections, as well as infections that were previously isolated to remote locales, are becoming more prevalent in several areas of Latin America. This article discusses some tropical infections and infestations with predominantly cutaneous manifestations. Previously uncommon diseases such as gnathostomiasis, mycobacteria ulcerans infection, paederus dermatitis, Balamuthia mandrillaris infection, and human T-lymphotrophic virus 1 dermatitis are increasingly being reported. Well-known tropical infections such as bartonellosis, leishmaniasis, chromomycosis, larva migrans, and larva currens are also becoming more prevalent. On the other hand, the incidence of Hansen's disease, the quintessential tropical infection, is dwindling all over the globe thanks to a highly effective eradication campaign launched by the World Health Organization. Because of increased immigration and tourist travel, the number of cases of these diseases in the United States may escalate.     

An outbreak of paederus dermatitis in a suburban hospital in Sri Lanka

Background In a modern hospital built recently in Sri Lanka the staff members on night shifts and some patients in the open wards were known to be affected by an acute vesicating dermatitis. The study was carried out to identify the cause of the dermatitis and recommend preventive measures. Methods Members of the hospital staff and patients who developed an acute vesicating dermatitis over a period of 2 years were studied using a questionnaire. The clinical features, relationship to night shifts and the month of occurrence were noted. Insects were caught at night on several occasions and identified. Lesions were reproduced in volunteers. Results Out of a total of 124 patients studied, 108 were members of the hospital staff and it was noted that they had all been on night shifts within 2 days prior to the onset of the lesions. The insect caught belongs to class Coleoptera, family Staphylinidae, genus Paederus, and species fuscipes. The incidence was seasonal with clustering of cases seen to occur twice a year. Conclusions This IS an outbreak of dermatltls due to Paederus fusicipes. Awareness of the condition and its clinical features will prevent misdiagnosis and the simple preventive measures suggested are based on the behavioral pattern of this nocturnal beetle.     

Influence of age and severity of dermatitis on the percutaneous absorption of hydrocortisone in children

The results of 55 4-h hydrocortisone absorption tests in 38 children with atopic or seborrhoeic dermatitis were analysed to evaluate the effect of age and severity of the dermatitis on percutaneous absorption of hydrocortisone. The children were divided into three groups on the basis of the severity of the dermatitis. The absorption of hydrocortisone caused a significantly higher mean rise of serum cortisol in 20 children with severe dermatitis (Group A) than in 17 children with moderate dermatitis (Group B). The mean post-application rise of serum cortisol in 18 children with mild dermatitis (Group C) was significantly lower than in the children with moderate dermatitis. There was a significant negative linear correlation between age and the post-application rise of serum cortisol in Groups A and C. In these groups the mean post-application rise of serum cortisol was significantly higher in children aged under 18 months than in children aged 18 months or over. Severe widespread dermatitis and an age under 18 months are two relevant risk factors in the topical use of hydrocortisone.     

Atypical and unusual clinical manifestations of contact dermatitis to clothing (textile contact dermatitis): case presentation and review of the literature

Although the exact incidence of textile contact dermatitis is unknown, recent studies demonstrate that contact dermatitis produced by allergic or irritant reactions to clothing not only is more frequent than previously thought but also increasing. The clinical features of contact dermatitis (CD) caused by clothing may resemble common allergic contact dermatitis or may have atypical presentations. We report on several cases of clothing-induced contact dermatitis with atypical clinical presentations.     

Airborne contact dermatitis from unexpected exposure to rosin (colophony)

We report 3 cases of contact dermatitis in rosin-sensitive individuals caused by exposure to airborne rosin components from different sources. Case no. 1 was a female office worker with a facial dermatitis caused by rosin components which emanated from the linoleum floor covering in her office. Floor material containing wood flour and rosin was released into the air, causing a facial dermatitis in the rosin-sensitive subject. Case no. 2 involved a woman who worked in a factory producing dairy product cartons and had a dermatitis on her lower legs, lower arms and upper chest. Her dermatitis was caused by dust from the paper cartons and contact allergy to rosin components probably aggravated her dermatitis. Case no. 3 was a female office worker with a relapsing dermatitis on her eyelids. Her dermatitis was caused by a rosin-containing floor polish, which was seen as a powder on the office floor. Extracts of suspected material and products were patch tested and analysed for the presence of rosin components with HPLC and GC techniques. A discussion and recommendations on chemical analyses of rosin components follow. We conclude that a thorough investigation, including chemical analyses, can rule out non-specific diagnoses and offer a solution to the patient's skin problems.