共查询到20条相似文献,搜索用时 15 毫秒
1.
Yuan Li Ze-Hong Wu Ke-Wu Zeng Ming-Bo Zhao Yong Jiang 《Journal of Asian natural products research》2017,19(7):738-743
A new prenylated flavone, 3,5,7,3′-tetrahydroxy-8,4′-dimethoxy-6-(3-methylbut-2- enyl)flavone (1), together with three known flavone derivatives (2–4), two known dihydrophenanthrenes (5–6), two known lignin derivatives (7–8), and three known phenolic glycoside compounds (9–11) were isolated from the n-BuOH extract of Pleione bulbocodioides. High-resolution electrospray ionization mass spectroscopy (HRESIMS), FTIR spectroscopy, and NMR techniques were used to elucidate the structures of these compounds. Biological investigations showed that compound 5, 4,7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene, exhibited potent anti-inflammatory activity on LPS-stimulated NO production in BV-2 microglial cells, with IC50 value of 5.44 μM. 相似文献
2.
Xiao Hu Mei-Hua Yu Gui-Rui Yan He-Yao Wang Ai-Jun Hou 《Journal of Asian natural products research》2018,20(5):488-493
A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (2–4) and five known Diels–Alder adducts (5–9), were isolated from the twigs of Morus nigra. Their structures were elucidated by spectroscopic methods. Sanggenon M (2), chalcomoracin (5), sorocein H (6), kuwanon J (7), sanggenon C (8), and sanggenon O (9) showed significant inhibitory effects on mushroom tyrosinase. 相似文献
3.
Chun-Lei Zhang Guo-Ru Shi Yan-Fei Liu Yan Wang Ruo-Yun Chen 《Journal of Asian natural products research》2017,19(2):128-133
Phytochemical investigation of the rhizomes of Iris tectorum resulted in the isolation and characterization of three new apocynin derivatives, apocynin-4-O-β-D-(6′-O-syringyl)glucopyranoside (1), scrophenoside C-7-ethyl ether (2, 3), together with a new naturally occurring compound but known by synthesis, apocynin-4-O-β-D-xylopyranoside (4), and five known ones (5–9). Their structures were elucidated on the basis of spectroscopic data interpretation. 相似文献
4.
Qing Zhao Jing-Zhi Yang Chuang-Jun Li Nai-Hong Chen 《Journal of Asian natural products research》2013,15(4):361-366
A new megastigmane glucoside (6S,7E,9S)-6,9,10-trihydroxy-4,7-megastigmadien-3-one 9-O-β-d-glucopyranoside (1) and a new amide alkaloid (E)-N-(4-methoxyphenethyl)-2-methylbut-2-enamide (2), together with three known amide alkaloids (3–5), were isolated from the leaves of Clausena lansium (Lour.) Skeels. Their structures were elucidated by their physicochemical properties and analysis of their spectral data. 相似文献
5.
Tran Thu Huong Le Huyen Tram Tran Thuong Quang Le Van Duong Nguyen Hoai Nam 《Journal of Asian natural products research》2013,15(9):923-928
Phytochemical study of the methanol extract of Artocarpus altilis resulted in the isolation of a new prenylated aurone, artocarpaurone (1), together with eight known compounds including two prenylated chalcones (2 and 3), three prenylated flavanones (4–6), and three triterpenes (7–9). The structure of 1 was elucidated as 6-hydroxy-2-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-ylmethylene]-3(2H)-benzofuranone by spectroscopic methods including 1D and 2D NMR spectra and FT-ICR-MS. Compound 1 showed moderate nitric oxide radical scavenging activity, whereas 2 and 3 had moderate 2,2-diphenyl-1-picrylhydrazyl radical scavenging effect, compared with the positive control (+)-catechin. 相似文献
6.
Ling-Jie Meng Qing-Lan Guo Cheng-Bo Xu Cheng-Gen Zhu Yu-Feng Liu Ming-Hua Chen 《Journal of Asian natural products research》2017,19(6):529-540
Six new indole alkaloid diglycosides named isatigotindolediosides A-F (1–6), along with three known analogs (7–9), were isolated from an aqueous extract of the Isatis indigotica roots (ban lan gen). Their structures including the absolute configurations were determined by comprehensive spectroscopic data analysis, combined with enzyme or acid hydrolysis, and comparison of experimental circular dichroism (CD) and calculated electronic circular dichroism (ECD) spectra. In the preliminary assays, compounds 3, 5, and 8 showed antiviral activity against Coxsackie virus B3. 相似文献
7.
Meng-Qin Bian Jie Kang Hong-Qing Wang Qing-Jian Zhang Chao Liu 《Journal of Asian natural products research》2013,15(5):459-464
From the seeds of Alpinia galanga Willd., three new norsesquiterpenoid racemic mixtures, galanols A–C (1–3) were isolated, along with three known sesquiterpenoids (4–6). Their structures were elucidated by means of UV, IR, HR-ESI-MS, 1D NMR and 2D NMR spectroscopic data. 相似文献
8.
Lian-Hai Shan Ji-Fa Zhang Feng Gao Shuai Huang 《Journal of Asian natural products research》2018,20(5):423-430
Five new C18-diterpenoid alkaloids, anthriscifoltines C-G (1–5), along with four known diterpenoid alkaloids anthriscifolcines C-F (6–9), were isolated from the extract of Delphinium anthriscifolium var. majus. Their structures were elucidated by extensive spectroscopic analyses (including 1D-, 2D-NMR, and HR-ESI-MS). Compounds 1–5 were also evaluated for their cytotoxic activity against MCF-7, HepG2, and H460 human cancer cell lines. 相似文献
9.
Ya-Ling Song Jin-Ming Gao Guan-Hua Du 《Journal of Asian natural products research》2013,15(3):214-217
Investigation on the EtOH extract of the fruits of Chaenomeles speciosa led to the isolation of a new triterpene acid bearing an unusual hydroperoxyl substitute group at C-11, speciosaperoxide (1), along with six known triterpenoids, 3β-acetoxyurs-11-en-13β,28-olide (2), 3-O-acetyl ursolic acid (3), oleanolic acid (4), ursolic acid (5), masilinic acid (6), and tormentic acid (7), and three known norsesquiterpenoids, roseoside (8), vomifoliol (9) and (6S,7E,9R)-6,9-dihydroxy-4,7-megastigmadien-3-one 9-O-[β-d -xylopyranosyl (1 → 6)-glucopyranoside] (10). Their structures were elucidated on the basis of spectroscopic data and comparison with reference data. Besides compound 1, compounds 2, 8–10 were obtained from this genus for the first time. None of these compounds exhibited inhibitory activity against T-and B-lymphocyte proliferation. 相似文献
10.
Three new alkaloids namely 8-(4-hydroxyphenyl)-6-methoxy-3,4-dihydroisoquinolin-1(2H)-one (1), 4-aminonigellidine (2), and N-[(4-hydroxy-2-isopropyl-5-methyl)]phenylurea (3), along with six known ones (4–9), were isolated from the seeds of Nigella glandulifera. The structures of 1–3 were determined through spectroscopic analyses (HRESIMS, 1D/2D NMR). Compound 1 was a rare isoquinolinone alkaloid with phenyl substituted at C-8. 相似文献
11.
Tarik A. Mohamed Taha A. Hussien Jui-Hsin Su Jyh-Horng Sheu Mohamed Elamir F. Hegazy 《Journal of Asian natural products research》2017,19(3):201-207
Three new cembrenoids, lobophylins F-H (1–3), along with three known ones, lobophylins A-C (4–6), were isolated from the ethyl acetate extract of the Taiwan water soft coral Lobophytum crassum. The structures of isolated cembrenoids were elucidated on the basis of extensive spectroscopic methods such as IR, 1D, 2D NMR and HR–ESI–MS. 相似文献
12.
Shan He 《Journal of Asian natural products research》2016,18(2):134-140
Three new compounds, including two new diterpenoids, named epianhydrocinnzeylanol (1) and cinnacasiol H (2), and one hydroxylasiodiplodin, (3R,4S,6R)-4,6-dihydroxy-de-O-methyllasiodiplodin (3), together with five known diterpenoids (4–8) and two known phenolic glycosides (9–10) were isolated from the barks of Cinnamomum cassia. Their structures were elucidated by extensive spectroscopic analysis and comparison of the chemical shift values with those of related known compounds. The anti-inflammatory activities of the isolates were evaluated on nitric oxide production in lipopolysaccharide-induced BV-2 microglial cells and the compounds showed weak inhibition activities. 相似文献
13.
Qiu-Fen Hu Yue-De Wang Dong-Lai Zhu Zhen-Hua Yu Jian-Bo Zhan Huan-Huan Xing 《Journal of Asian natural products research》2016,18(12):1115-1121
Phytochemical investigations on the ethanol extract of the twigs of Garcinia tetralata resulted in the isolation of three new biphenyls, tetralatabiphenyls A–C (1–3), along with three known biphenyl derivatives (4–6). Structural elucidations of 1–3 were performed by spectroscopic methods such as 1D and 2D NMR spectra, in addition to high-resolution mass spectra. Compounds 1–6 were also evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compound 3 showed high anti-TMV activity with inhibition rate of 31.1%. Compounds 1, 2, and 4–6 also showed modest anti-TMV activities with inhibition rates in the range of 18.9–24.5%, respectively. 相似文献
14.
From the fruits of Celastrus orbiculatus Thunb., a new dihydroagarofuran sesquiterpene ester named 6α,13β-diacetoxy-1β,8β,9β-tribenzoyloxy-β-dihydroagarofuran (1) has been isolated, along with three known compounds: 1β,6α,8β-triacetoxy-9α-benzoyloxy-β-agarofuran (2), 1β,6α-diacetoxy-9α-benzoyloxy-β-dihydroagarofuran (3) and β-sitostrol (4). The structure of 1 was elucidated on the basis of spectroscopic methods. 相似文献
15.
Diterpenoids from the freshwater green algae Rhizoclonium hieroglyphicum with antibacterial activity
Rosa Martha Perez Gutierrez Efren Garcia Baez 《Journal of Asian natural products research》2013,15(10):934-941
Three new isopimarane diterpenes 7β-hydroxy-19α-methylmalonyloxy-isopimara-8(14),15-diene (1), 7β-hydroxy-14-oxo-isopimara-8(9),15-dien-19oic acid (2), and 7β-hydroxy-14-oxo-19α-methylmalonyloxy-isopimara-9(11),15-diene (3) in addition to the known compounds isopimaric acid (4), 7oxo-13-epi-pimara-14,15-dien-18oic acid (5), 7oxo-13-epi-pimara-8,15-dien-18oic acid (6), and 6β-hydroxyisopimaric acid (7) were isolated from the hexane extract of Rhizoclonium hieroglyphicum. The structures of compounds 1–7 were established by 1D and 2D NMR techniques. The isolated diterpenoids were screened for antimicrobial activity against gram-positive and gram-negative bacteria and yeast strains. 相似文献
16.
Wei-Sheng Feng Xin-Yu Zang Xiao-Ke Zheng Yan-Zhi Wang Hui Chen Zhen Li 《Journal of Asian natural products research》2013,15(7):557-561
Two new dihydrobenzofuran lignanosides, (7R,8S)-4,3′,9′-trihydroxyl-3-methoxyl-7,8-dihydrobenzofuran-1′-propylneolignan-9-O-(6-O-syringoyl)-β-d-glucopyranoside, named lophanthoside B (1) and (7R,8S)-4,9,9′-trihydroxyl-3-methoxyl-7,8-dihydrobenzofuran-1′-propylneolignan-3′-O-β-d-glucopyranoside (2), an enantiomer of umbroside, along with four known dihydrobenzofuran lignans (3–6), were isolated from 50% acetone extract of Rabdosia lophanthoides (Buch.-Ham.ex D.Don) Hara. Their structures were elucidated by NMR and MS experiments. 相似文献
17.
Tong Zhang Ya-Zhong Zhang Jian-Sheng Tao Shanghai University of Traditional Chinese Medicine Cai-Lun Road Shanghai China 《Journal of Asian natural products research》2013,15(5):479-485
Bioassay-guided fractionation led to the isolation of eight compounds from Stemona sessilifolia. Of the eight isolates, three new bibenzyls, stilbostemins M–O (1–3), and a new tocopherol, 6-methoxy-3,4-dehydro-δ-tocopherol (4) were revealed together with four known compounds 3,5-dihydroxy-2′-methoxy bibenzyl (5), 3,5-dihydroxy bibenzyl (6), β-tocopherol (7), and γ-tocopherol (8). Compounds 5, 6, and 8 exhibited strong antibacterial activities against Staphylococcus aureus and S. epidermidis. 相似文献
18.
Phan Nhat Minh Mai Dinh Tri Nguyen Tan Phat Bui Trong Dat Nguyen Ngoc Hanh Ngo Quoc Luan 《Journal of Asian natural products research》2013,15(4):338-342
From the leaves of Cleome chelidonii L.f., two new flavonol glycosides, named cleomesides A (1) and B (2), and four known compounds, quercetin 3-O-β-glucopyranosyl(1 → 2)-α-rhamnoside-7-O-α-rhamnoside (3), ethyl α-galactopyranoside (4), adenine (5) and glycerol monostearate (6), were isolated. The structures of all isolated compounds (1–6) were determined by NMR spectroscopy and mass spectrometry. The data of known compounds (3–6) were further compared with the reported data for these compounds. 相似文献
19.
Hong-Xiu Hu Ran-Ran Gao Zhao-Hui Gao Yue Qiao Xin-Ran Dong Gang Ding 《Journal of Asian natural products research》2018,20(7):624-632
AbstractThree new (6, 9, and 12) and nine known steroidal saponins were obtained from the fermentation broth of pseudoprotodioscin (PPD) incubated with a fungus Gibberella fujikuroi CGMCC 3.4663. Structures of the metabolites were elucidated by 1-D (1H, 13C), 2-D (HMBC, HSQC, NOESY) NMR, and HR-MS analyses. The biotransformation pathway of pseudoprotodioscin by Gibberella fujikuroi CGMCC 3.4663 was proposed. Compounds 1–11 were tested in vitro for their cytotoxic activities against two human cancer cell lines (HepG2 and Hela). Compounds 1, 6, 9, and 10 exhibited cytotoxic activity against HepG2 cells. Compound 10 exhibited cytotoxicity to Hela cells. 相似文献
20.
Ji-Fa Zhang Yu Li Feng Gao Lian-Hai Shan 《Journal of Asian natural products research》2019,21(7):716-724
Four new C20-diterpenoid alkaloids, rotundifosines D-G (1–4), along with eight known ones (5–12) were isolated from the whole plant of Aconitum rotundifolium Kar. & Kir. The structures of the compounds were elucidated on the basis of spectroscopic analyses, including HR-ESI-MS and 1D, 2D NMR. Rotundifosine F (3) is a rare C20-diterpenoid alkaloid with quaternary ammonium salt. Alkaloids 1–4, 5, 6, 9, and 12 were evaluated for cytotoxicity against MCF-7, HCT-116 and HepG2 human cancer cell lines. 相似文献