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目的对比分析骨性Ⅲ类错手术与非手术治疗的临床疗效。方法选取2001年2月至2007年3月福建医科大学附属口腔医院正畸科同一名医生使用固定矫治器矫治的骨性Ⅲ类错患者11例为非手术组,经正畸-正颌手术联合矫治的骨性Ⅲ类错患者11例为手术组。对两组病例治疗后X线头颅侧位片进行测量分析并比较。结果在硬组织方面,手术组与非手术组矫治后ANB角、SNA角、Wits值、L1-NB角及L1-NB距差异有统计学意义(均P<0.05);在软组织方面,除S-N’-Sn角组间差别有统计学意义(P<0.05),其余测量项目无明显差别(P>0.05)。结论骨性Ⅲ类错畸形手术治疗效果较非手术治疗好。     

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?? Objective    To compare the clinical curative effect of different casting fixed function appliances for skeletal Class ?? malocclusion. Methods    Totally 36 patients with skeletal Class ?? malocclusion who visited our hospital from May 2013 to October 2015 were induded as the research objects?? under the patients' informed consent and by random number table method they were divided into control group and experimental group ??18 cases in each group????control group took casting herbst functional appliance as orthodontic treatment??experimental group took casting fixed Twin-block function appliances??compare  clinical curative effect and chairside time between the two groups. Results          There was no statistically significant difference between the two groups concerning the value of head shadow ??P > 0.05??. There was statistical difference on chairside time between the two groups ??P < 0.05??. Conclusion    Treatment effects of two different functional appliances??Twin-block and Herbst??are similar in the early treatment of skeletal Class ?? malocclusion?? Compared with Herbst?? TB is more convenient to both orthodontic doctors and patients.     

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??Objective    To compare the changes of soft and hard tissues before and after treatment in adults with bi-maxillary dentoalveolar treated by miniscrew implants and transpalatal arch anchorage. Methods    Thirty adults aged above 18 with bi-maxillary dentoalveolar in hospital from Jan.2012 to Jan.2015 were included and randomly divided into two groups. All were treated by Mclaughlin Bennett Trevisi??MBT??sliding straight wire appliance??patients in observation group were anchored by miniscrew implants??while patients in control group were anchored by transpalatal arch combined with Nance arch. The changes in hard and soft tissues and the clinical effects were analyzed in both groups by lateral cephalometric measurement before and after active orthodontic treatment. Results    Miniscrew implants in one case in the observation group were lost??while in the control group nine cases showed repeatedly loosening and one case showed desoldering. The differences on anchorage stability had statistical significance??P??0.05??. The clearance time in the observation group was significantly shorter than that in the control group??P??0.05??. The change in U6A-Sv?? U6S-Sv?? L6A-Sv and L6S-Sv in the observation group was significantly less than in the control group??P??0.05???? while the change in U1A-Sv??U1E-Sv and L1E-Sv in the observation group was significantly more than in the control group??P??0.05??. The change in Ls-E in the observation group was significantly more than that in the control group??P??0.05??. Conclusion           For adults with bi-maxillary dentoalveolar??the miniscrew implants anchorage can control molar and incisor better??improve the soft tissue profile and reduce the gap closing time.     

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?? Objective    To evaluate the efficacy between low-level diode laser with 810 nm and rhEGF gel in the treatment of recurrent aphthous ulcer ??RAU??. Methods    A total of 60 RAU patients were randomly divided into experimental and control groups??with 30 cases in each group. Experimental group received diode laser for local irradiation therapy??the control group received drug treatmemt with rhEGF gel until ulcer healing. The course of treatment was one week. Results    Compared with control group??the experimental group has more obvious reduction of pain from baseline values??shorter median healing time and better efficacy. The differences were statistically significant??P??0.05??. There was no statistical difference on recurrence rate ??P > 0.05??. However?? within the next one month??there was no recurrence on treatment areas in experimental group. Conclusion    Diode laser treatment for RAU proves to be more stable and lasting in pain relieving and proves to be more obvious in accelerating healing time. Recurrence rate also can be reduced in the same area in short term. Laser therapy is more effective in the treatment of RAU compared with the rhEGF gel.     

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??Abstract??Objective To make doctor perform operation accurately on patients with dentomaxillofacial deformity by preoperative simulation based on digital data which was collected by digital software. Methods Fifteen patients had previously undergone 3-dimensional computed tomography and the data from CT scan were input into digital software. We used the software to simulate operations preoperatively including fixing point??osteotomies and movements of jaw bones. The collected information from software was applied to actual operations. Results All the operations had been completed successfully without serious complication. The patients were satisfied with the effect of operation 6 months after operation??with a satisfaction rate of 93.3%. Conclusion The digital simulation technique is a precise method which provides practical and effective basis for establishing the preoperative planning of individual optimal surgical procedure for patients with dentomaxillofacial deformities in orthognathic surgery.     

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目的探讨腮腺多形性腺瘤的治疗方法。方法通过对1992—2009年江苏省徐州市第六人民医院口腔科收治的148例腮腺多形性腺瘤患者的临床资料进行总结,比较分析腮腺浅叶切除术(88例患者)与腮腺区域性切除术(60例患者)两种术式治疗腮腺多形性腺瘤的效果。结果采用腮腺区域性切除术治疗的病例,术后瘢痕、局部凹陷畸形、暂时性面瘫、涎瘘、Frey综合征及腮腺功能等方面明显优于采用腮腺浅叶切除术的病例。两种术式的术后复发率差异无统计学意义。结论应根据肿瘤的部位及大小选择不同的术式,对界限清楚、体积较小的腮腺浅叶多形性腺瘤应尽量采用腮腺区域性切除术,预防面部凹陷畸形,减少并发症;对过大或边界不清的肿瘤仍宜采用传统腮腺浅叶切除术,以减少复发。     

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目的探讨关节腔注射透明质酸钠治疗间接性颞下颌关节(TMJ)损伤后并发关节功能紊乱患者的临床疗效。方法选择2009年5月至2011年5月甘肃省嘉峪关市第一人民医院口腔科收治的因间接性TMJ损伤并发关节功能紊乱且经保守治疗无效的患者40例,将其随机分为两组:治疗组20例,关节腔冲洗后注射透明质酸钠;对照组20例,单纯行关节腔冲洗。观察两组患者治疗前后关节疼痛、开口度和侧向活动度的变化。结果经过1个疗程(每周1次,3周为1个疗程)治疗后,两组患者的关节疼痛、开口度和侧向活动度均较治疗前改善;组间比较结果显示,治疗组关节疼痛、开口度和侧向活动度的改善程度均较对照组明显,差异有统计学意义(P<0.01)。结论关节腔注射透明质酸钠治疗间接性TMJ损伤后并发关节功能紊乱病的疗效优于单纯进行关节腔冲洗;透明质酸钠可以明显改善间接性TMJ损伤并发关节功能紊乱患者的疼痛症状、开口度和侧向活动度。     

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目的评价含生物活性玻璃成分的脱敏剂与氟保护漆联合应用对牙本质小管的堵塞效果及治疗牙本质过敏症(dentin hypersensitivity,DH)的临床疗效。方法选择2013年6月到2014年6月到中国医科大学口腔医学院干诊科就诊的59例DH患者的120颗患牙,随机分为A组(41颗)、B组(39颗)、C组(40颗),分别使用氟保护漆、奥敏清及氟保护漆与奥敏清联合涂布敏感处,应用视觉模拟评分(visual analogue scale,VAS)法评价其疗效。另选择因正畸需要拔除的完整无龋坏前磨牙20颗,制备成敏感模型后随机分为a、b、c、d四组,每组5颗,a、b、c三组处理方法同上述A、B、C组,d组为空白对照组,用蒸馏水进行处理,扫描电镜观察各组牙本质小管的堵塞情况。结果 A、B、C三组的VAS评分值在处理即刻均明显下降,且随时间推移均有增高趋势;有效率比较,A、C两组在1个月时差异有统计学意义(P<0.05),其他各组间在各时点差异均无统计学意义(P>0.05);各组内比较,A组即刻与1个月时差异具有统计学意义(P<0.05)。扫描电镜观察a、b、c三组牙本质小管均有不同程度堵塞,其中以联合应用组效果最佳。结论含生物活性玻璃成分的脱敏剂与氟保护漆联合应用堵塞牙本质小管的效果最佳,且具有较好的临床效果。     

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??Objective    To evaluate the sealing effect of a dentin adhesive in Class??restorations. Methods    Standardized mixed Class??cavities??2 mm × 2 mm × 2 mm??were prepared in 120 extracted premolars that were randomly assigned to 4 groups??n=30 for each group??. Three adhesive systems??All Bond Universal??total-etch and self-etch????Prime & Bond NT??and G bond and resin composite??were applied to each group following manufactures′ instructions. The teeth were immersed in 50 % ammoniacal silver nitrate and depth of penetration was evaluated under a microscope??and data were statistically analyzed by SPSS 20.0 software. Results    Microleakage was observed in all groups. All Bond Universal??total-etch??scores were lower than the other two groups??P??0.05??. There was no difference between total-etch and self-etch when All Bond Universal was used??P??0.05??. Higher microleakage scores were observed along the gingival margin than along the occlusal margin in all groups??P??0.05??. Conclusion    New universal adhesive ??All Bond Universal?? is a convenient and efficient adhesive. Total-etch and self-etch have no influence on marginal microleakage the long-term effect need further study.     

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目的    探讨重组人表皮生长因子（rhEGF）凝胶治疗复发性口腔溃疡的临床疗效。方法    采用随机平行对照试验方法,将2007-2009年辽宁省人民医院口腔科收治64例复发性口腔溃疡（ROU）患者随机分为试验组和对照组,试验组用rhEGF凝胶局部涂药,对照组给予2%碘甘油局部涂药,分组观察,2组均治疗至溃疡愈合或2周止。结果    试验组患者溃疡平均愈合时间为（3.52±1.29）d,对照组为（7.58±2.07）d,两组比较,差异有统计学意义（P < 0.05）。试验组总有效率（96.9%）明显高于对照组（62.5%）（P < 0.05）。结论    重组人表皮生长因子凝胶对口腔溃疡创面具有明显的促进愈合作用,应用方便、安全。     

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目的探讨透明质酸钠关节上腔和关节下腔注射在治疗颞下颌关节骨关节病中的疗效。方法选择2006年7月至2009年2月威海市立医院口腔门诊适合注射透明质酸钠的46例颞下颌关节骨关节病患者,随机分为试验组和对照组,试验组25例采用关节下腔注射透明质酸钠,对照组21例采用关节上腔注射,比较两组疗效的差异。结果张口度对照组平均增加(0.96±0.13)cm,试验组平均增加(1.28±0.09)cm,两组间差异有统计学意义(P<0.01);关节疼痛对照组平均缓解(23.43±9.62)mm,试验组平均缓解(29.08±10.51)mm,两组间差异有统计学意义(P<0.01)。治疗后3个月至6个月的症状改善进行比较,张口度对照组变化为(0.01±0.03)cm,试验组为(0.08±0.04)cm,差异无统计学意义;关节疼痛改善对照组为(1.64±0.56)mm,试验组为(4.24±0.79)mm,差异具有统计学意义(P<0.01)。结论透明质酸钠关节上、下腔注射对颞下颌关节骨关节病确有疗效,关节下腔注射较上腔注射对缓解患者的关节疼痛和改善张口度的效果更为明显,且对疼痛缓解的作用时间更持久。     

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目的    探讨生芦润燥汤治疗干燥综合征的临床疗效。方法    选取2007年5月至2008年12月上海中医药大学附属市中医医院风湿科及口腔科门诊收治的60例干燥综合征患者,随机分为试验组和对照组,每组30例。试验组服用生芦润燥汤治疗,对照组服用硫酸羟氯喹治疗,两组疗程均为12个月。治疗期间每3个月随访1次,观察并记录两组患者治疗前后的症状、体征及实验室检查结果。结果    试验组疗效与对照组疗效有显著差异（P < 0.01）;在改善症状、体征和中医征候方面,试验组明显优于对照组（P < 0.01）。结论    生芦润燥汤治疗干燥综合征有显著疗效。     

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??Objective    To explore the responses of patients with all types of burning mouth syndrome to low-level laser therapy. Methods    Totally 90 BMS patients were randomly divided into 3 groups??30 cases in each group. Group A and B were treated with low-level laser?? and therapeutic regimens were one time a day for continuous irradiation of 20 days??group A???? and every other day for ten times??group B???? respectively. Group C was treated with non-irradiation light?? one time a day for continuous irradiation of 20 days. Group A?? B and C were all given routine medication. Before and after the treatment and in the one-month follow-up?? the pain ??VAS score?? and the total effective rates were measured. Results    Statistically significant difference ??P??0.05?? was found between group A and B in the change of VAS after treatment?? and the total effective rates of group A and B were significantly higher than that of group C. The total effective rate of type 2 BMS was significantly higher than that of type1 and 3. There was no significant difference among groups and types of BMS in the VAS scores and the total effective rates between one-month follow-up and after the treatment ??P??0.05??. Conclusion    Low-level laser is effective in the treatment of BMS?? especially for type 2. In a certain period of time?? there is no difference in the effect with different irradiation times under the same irradiation dose parameters.     

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目的研究前方牵引联合唇挡矫治替牙期骨性Ⅲ类错的临床疗效。方法选择2010—2011年大庆油田总医院集团五官医院口腔正畸科门诊就诊的替牙期上颌发育不足的骨性Ⅲ类错患者30例。随机分为试验组和对照组,各15例。试验组使用前方牵引联合唇挡进行矫治;对照组则仅使用前方牵引矫治。在治疗前后对所有患者进行X线头影测量分析并比较组间差异。结果试验组治疗前后变化差值与对照组比较,X线头影测量分析结果显示,SNA、ANB、U1-SN、U1-NA角、U1-NA距、Ptm-U6差异均有统计学意义(P<0.01);模型测量结果显示,TAL、AD、拥挤度差异亦均有统计学意义(P<0.01)。结论采用前方牵引和唇挡联合矫治替牙期骨性Ⅲ类错,可有效消除单一采用前方牵引矫治带来的负面影响,是一种切实可行的办法。     

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目的    探讨可吸收性胶原生物膜应用于齿槽裂植骨修复的临床效果。方法    选择2006—2009年在广东省口腔医院口腔颌面外科就诊的单侧齿槽裂患者108例,年龄9 ~ 13岁,随机分为2组。对照组60例单纯应用髂骨松质骨行植骨修复,试验组48例应用髂骨松质骨加可吸收胶原生物膜覆盖行植骨修复。术后1周及3、6、12个月行X线检查。结果    试验组植骨成活率和临床成功率（97.9%、79.2%）高于对照组（86.7%、58.3%）,差异有统计学意义（P < 0.05）。结论    自体髂骨加可吸收胶原生物膜联合应用于齿槽裂植骨修复中,可有效提高植骨成功率,为后续治疗提供更好保障,值得临床推广。     

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??Objective??To assess the efficacy of oral propranolol combined with topical timolol maleate in the treatment of infantile parotid hemangiomas. Methods??Twenty-seven infants with parotid hemangiomas were hospitalized in Department of Oral and Maxillofacial Surgery?? Hospital of Stomatology?? China Medical University??from September 2013 to September 2015. The study group consisted of 9 males and 17 females?? aged between 2 months to 9 months?? with a median age of 4.8 months. The lesions were all located in the parotid region??and measured between 1.5 cm × 2.0 cm × 1.0 cm and 7.0 cm × 6.0 cm ×3.0 cm in size. Propranolol was administered orally at a dose of 1.0??1.5 mg/??kg·d???? 0.5% timolol maleate eye drop solution was applied topically with medical cotton swabs to the area of the lesion twice a day. The therapy duration was 12 to 32 weeks?? averaged 20.3 weeks. The follow-up duration was from 3 months to 12 months?? averaged 8.4 months. Record the colors?? volumes?? textures?? and ultrasonic results of hemangiomas before the treatments and at the end of treatments. Results??Of the 27 patients??21 demonstrated an excellent response ??77.8%????4 showed a good response ??14.8%????and 2 displayed a moderate response ??7.4%????cure rate was 77.8%??and effective rate was 100%. Conclusion??Overall??oral propranolol combined with topical timolol maleate is an effective treatment method for infantile parotid hemangioma??and is worth promoting.     

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目的探讨中药离子导入治疗颞下颌关节紊乱病(TMD)的临床疗效。方法将2000年11月至2007年11月大连大学附属中山医院确诊的TMD患者212例,随机分为试验组(中药离子导入组)109例,采用中药溶液湿热敷配合电脑中频药物导入治疗仪治疗;对照组(药物治疗组)103例,采用传统口服药治疗。治疗2周后对比观察临床疗效。结果试验组及对照组的治疗有效率分别为90.83%和78.64%,两组差异具有统计学意义,(χ2=6.13,P<0.05),试验组有效率明显高于对照组。结论中药离子导入治疗TMD是一种具有较好应用前景的治疗方法,为中药治疗TMD提供了一种新的给药途径。     

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目的探讨金栀洁龈含漱液对中重度牙周炎患者的临床治疗效果。方法选择2009年10月至2010年10月在辽宁省人民医院口腔科就诊的中重度牙周炎患者60例,牙周基础治疗后,随机分为2组,试验组选取中药金栀洁龈含漱液对牙周袋进行冲洗维护,对照组常规选取双氧水进行牙周袋冲洗维护,两组治疗前后均进行牙周病相关临床指标菌斑指数(PLI)、出血指数(BI)、探诊深度(PD)、附着丧失(AL)的记录及龈沟液中炎性因子白细胞介素-6(IL-6)质量浓度的测定。结果经过5周的牙周系统治疗和金栀洁龈含漱液、双氧水的牙周袋冲洗治疗后,试验组和对照组牙周炎患者的BI、PD、AL及龈沟液中IL-6质量浓度均比治疗前有改善,但试验组比对照组改善更加明显,差异有统计学意义(P<0.05)。试验组和对照组PLI的组间对比差异无统计学意义(P>0.05)。结论金栀洁龈含漱液在治疗中重度牙周炎患者时疗效显著,值得在临床上推广使用。     

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目的探讨Cortisomol糊剂对预防根管治疗术后疼痛的临床疗效。方法选择2005年1月至2007年12月在辽宁协和整形外科医院博爱口腔科就诊,患急、慢性根尖周炎及牙髓坏死需接受根管治疗的362例患者共计376颗牙为受试对象,随机分成试验组(n=186)和对照组(n=190)。试验组常规根管消毒后行Cortisomol糊剂加牙胶尖永久性根管充填;对照组行酚醛复合制剂加牙胶尖永久性根管充填。比较两组患牙根管治疗术后指标的情况。结果行Cortisomol糊剂永久充填术后发生疼痛患牙为21颗(11.29%),对照组发生疼痛患牙为41颗(21.58%),经统计学检验,两组有差异有统计学意义(P<0.01)。两组患牙治疗效果评价,试验组治疗效果好171例(91.93%),效果一般12例(6.45%),效果差3例(1.61%);对照组治疗效果好157例(82.6%)效果一般26例(13.68%),效果差7例(3.68%),两组比较差异有统计学意义(P<0.05)。对照组中曾有1例患者发生急性疼痛。结论行Cortisomol糊剂永久根管药物充填,可有效预防根管治疗术后疼痛的发生。     

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目的评价钛酸钡(BaTiO3)压电陶瓷涂层对种植支抗稳定性及其周围骨改建情况的影响。方法本研究于2013年8月至2014年1月在兰州军区总医院进行。选择5只成年杂种犬,将机械处理表面支抗种植钉(对照组)植入犬左侧下颌骨,BaTiO3压电陶瓷涂层支抗种植钉(实验组)植入犬右侧下颌骨,每侧各2枚;术后2周,给予1.96 N交互牵引力持续1个月,测量2枚种植体位移并通过影像学检查、组织学染色分析、生物力学检测观察种植支抗稳定性及其与周围骨结合的效果。结果与对照组相比,实验组BaTiO3压电陶瓷涂层种植支抗移动距离明显减小,骨形成活跃,骨结合率及最大拔出力显著升高,组间差异具有统计学意义(P<0.05)。结论在种植支抗表面制备BaTiO3压电陶瓷涂层可有效增加种植支抗的稳定性。